BOL: Related items

2 positions on the evolutionary analysis of biological sequences in Montpellier - France

Mon, 28 Sep 2015 08:25:48 -0500

The Methods and Algorithms for Bioinformatics (MAB) team at the LIRMM (computer science, robotics and microelectronics laboratory at the CNRS & University of Montpellier, France) is looking for talented individuals to fill two postdoctoral positions. We are seeking candidates with a strong background in computational evolutionary biology. The positions will start by the end of 2015.

The first of the positions (duration: 18-24 months), associated with the European VIROGENESIS project (http://www.kuleuven.be/english/research/EU/p/horizon2020/sc/sc1/Virogenesis), concerns the evolutionary analysis of viral sequences. Topics include -- but are not limited to -- phylogenetic classification of metagenomic reads and the recombination history of viruses.

The second position (duration: 1 year), associated with the Institute for Computational Biology (IBC, http://www.ibc-montpellier.fr), concerns evolutionary analyses of large-scale genomic data -- including the inference of very large phylogenies, gene/species tree reconciliation, comparative genomics, phylogenetic network inference and verification, phylogeography, the use of phylogenies to study the evolution of characters.

A one thousand year old city, Montpellier is a thriving research community with a multitude of biology and biomedical research centers. It is the fastest growing city in France where approximately one third of the population are students, and a wonderful location for outdoor activities (kite/wind surfing, sailing, river/sea kayaking, hiking and rock climbing). The LIRMM is one of the most visible computer science laboratories in France.

Quick next generation sequencing (NGS) terms definition

Neel — Fri, 09 Jun 2017 04:52:26 -0500

fragment size: the Illumina WGS protocol generates paired-end reads from both ends of longer fragments. The lengths of these fragments are assumed to be sampled from a normal distribution. Therefore, in the absence of structural variants, mapping locations of the paired ends span within an interval [δmin,δmax]. Most (>90%) of paired-end reads are sampled from no-SV regions, therefore the fragment size distribution can be learned empirically for each WGS data set separately.

concordant reads: a read pair is called concordant if they can be mapped to the reference genome as “expected”: (a) mapped to opposing strands where the upstream read is mapped to the forward strand and the downstream read is mapped to the reverse strand2, (b) the distance between ends is between the minimum and maximum expected fragment size.

discordant reads: briefly, any non-concordant read pair is considered discordant. Note that, by definition, the discordant read pairs signal potential SVs. The sequence signature produced by these type of reads is known as read-pair signature.

split reads: a read that can only be mapped to the reference genome by breaking into two sub-reads is called a split-read. These types of reads also indicate a potential SV or a short insertion or deletion (indel).

read depth: number of reads that map within a region of the genome. Overall genome-wide read depth is also referred to as depth of coverage. It is expected that the number of reads that “cover” each base-pair to follow a Poisson distribution. Therefore, if the read depth over a certain region deviates significantly from this distribution, it signals for a potential copy number variation (CNV).

SRF/JRF Bioinformatics at IARI

Sun, 29 Nov 2015 03:00:44 -0600

Agricultural Knowledge Management Unit

ICAR-INDIAN AGRICULTURAL RESEARCH INSTITUTE

L.B.S Building, Pusa Campus,

New Delhi-110012

Walk-in-Interview: 18th December 2015

DBT funded project: Distributed Information Centre under BTISnet (PI: Dr. A.K.Mishra)

Senior Research Fellow Two

Rs 28000/- + HRA

i) Master’s degree in Bioinformatics or Computer Science+ NET qualification and two years research experience, or

ii) M. Tech degree in Bioinformatics or Computer Science /Engineering with two years research experience Efficiency to handle agricultural databases and bioinformatics tool development

#Junior Research Fellow

Rs. 25000/- + HRA

i) Master’s degree in Bioinformatics or Computer Science + NET qualification, or

ii) M. Tech degree in Bioinformatics or Computer Science/Engineering Efficiency to handle agricultural databases and bioinformatics tool development

Traineeship Two

Rs. 8000/- consolidated

M.Sc./M. Tech (Bioinformatics) with 60 % marks from a recognized University

Studentship Four

Rs. 8000/- consolidated

Final year M.Sc./ M.Tech (Bioinformatics) Students from a recognized University

* M. Tech with Four Years Bachelor’s degree followed by Master’s degree

# In case suitable person is not found for SRF position, it may be filled at the JRF level The interview will be held on 18 th December 2015 at 10:00 AM at AKMU, LBS Building, IARI, Pusa Campus, New Delhi-110012. Terms and Conditions:  Maximum age limit is 35 years for all positions. Age relaxation of 5 yrs for SC/ST/OBC and woman candidates will be given.  The above post is purely temporary and is co-terminus with the project. The candidate shall not claim for regular appointment.  No TA/DA will be paid for attending the interview.  Bring self attested copies and originals of all certificates ( class 10th )onwards along with biodata in the attached format, proof of date of birth, one passport size photo, NOC from present employer, if any  Canvassing in any form will disqualify the candidate. 

Reporting time for interview: 9.30-10.00 AM at AKMU, IARI, New Delhi -110 012

www.iari.res.in/files/SRF_JRF_Akkmu-27112015-20151127-124003.pdf

RA Bioinformatics at NIPGR

Tue, 20 Oct 2015 04:11:56 -0500

Applications are invited from suitable candidates for filling up the purely temporary positions of one Research Associate (RA) and one Junior Research Fellow (JRF) in the DBT Part-B Sub-project-1&2 entitled Transcriptome and epigenome diversity analysis during seed development for discovery of molecular markers and gene regulatory mechanism in chickpea of Seed Biology

Research Associate (one post): Emoluments as per DST/DBT norms & as sanctioned in the project
Qualification: Candidates having Ph.D. degree (awarded) in Life Sciences/Molecular Biology/Bioinformatics or related field are eligible to apply.

Junior Research Fellow (one post): Emoluments as per DST/DBT norms & as sanctioned in the project
Qualification: Candidates having M.Sc. degree or equivalent (with minimum 55% marks) in Life Sciences, Biotechnolgy, Bioinformatics, Molecular Biology or any other related field are eligible to apply

Additional Information

Address:
Staff Scientist
National Institute of Plant Genome Research (NIPGR)
Aruna Asaf Ali Marg, P.O. Box NO. 10531,
New Delhi - 110067

States & U.T
State & Union Territories Delhi

How To Apply

Apply Details
Eligible candidates may apply by sending their complete application in the given format. The attested copies of the certificates and proof of research experience (if any) are to be attached with the hard copy of application. The applications should reach at the address given below within 15 days from the date of advertisement.

Web/Notification URL
http://www.nipgr.res.in/careers/vacancie s_latest.php

RNA-seq Analysis Workshop Course Materials

Jit — Tue, 03 Jul 2018 08:14:14 -0500

RNAseq can be roughly divided into two "types": Reference genome-based - an assembled genome exists for a species for which an RNAseq experiment is performed. It allows reads to be aligned against the reference genome and significantly improves our ability to reconstruct transcripts. This category would obviously include humans and most model organisms but excludes the majority of truly biologically intereting species (e.g., Hyacinth macaw); Reference genome-free - no genome assembly for the species of interest is available. In this case one would need to assemble the reads into transcripts using de novo approaches. This type of RNAseq is as much of an art as well as science because assembly is heavily parameter-dependent and difficult to do well. In this lesson we will focus on the Reference genome-based type of RNA seq. http://chagall.med.cornell.edu/RNASEQcourse/

Address of the bookmark: http://chagall.med.cornell.edu/RNASEQcourse/

Project Assistant BioInformatics

Mon, 02 Nov 2015 03:23:09 -0600

Project Assistant BioInformatics

Eligibility : ME/M.Tech(Bio-Informatics/Bio-Chemistry Engg), MSc(Bio-Informatics), BE/B.Tech

Location : Pune

Last Date : 16 Nov 2015

Hiring Process : Face to Face Interview

No. Bio/NCIM/3

Project Assistant II Jobs opportunity in National Chemical Laboratory (NCL) on temporary basis

Project Code No. : GAP312626

Title of the Project : Microbial ecology and distribution of geochemical cycling genes in an hot spring ecosystem

No. of Post : 01

Qualifications : M.Sc./B.Tech/M.Tech in Computational biology/ Bioinformatics from recognized university with minimum 60 % marks (aggregate)

Desirable : Good knowledge of computational skills, Linux (command line and GUI) and Unix; Perl / Python / R /C-programming. Practical knowledge of analysis of Next generation sequence datasets (amplicon sequencing, whole metagenome, and complete genome sequencing) with reference to microbes. Analysis and statistical validation of NGS data generated from different chemistry platforms. Some wet-lab experience in microbial system would be an added advantage as project involves some travel.

Emoluments : Rs. 16,000/-

Age Limit : 28 years

The application with the above information duly signed together with photo-copies of relevant certificates/testimonials should be addressed to : The Head, NCIM Resource Centre (Attn Dr. M.S. DHARNE), National Chemical Laboratory, Pune 411 008, so as to reach on or before 16th November 2015.

More at http://www.ncl-india.org/files/JoinUs/JobVacancies/TemporaryJobs.aspx?menuid=ql6&childmenustripid=divSubQL6

Pre- or postdoctoral research fellowship in Structural Bioinformatics at Padova

Thu, 05 Nov 2015 22:15:12 -0600

A research fellowship for a software developer is available at the BioComputing UP Laboratory, University of Padova (URL: http://protein.bio.unipd.it/).
A highly motivated and creative candidate is sought to work on structural bioinformatics. Specifically, the project entails the development of novel methods, tools and databases for the analysis of protein structures.

The BioComputing UP Laboratory, headed by Prof. Silvio Tosatto, is a dynamic group of a dozen people working on several aspects of prediction of protein structure & function employing techniques at the intersection between biology, medicine, chemistry, physics & computer science.
Our aim is to integrate the development of novel methods and their application to biologically relevant problems.

We are looking for candidates with a solid Bioinformatics background, programming experience (Python, C++ and/or Java) and good knowledge of molecular biology (protein structure/function). Good knowledge of statistics as well as experience in using database systems (MongoDB, MySQL and/or Postgres) is desirable. Candidates should have a degree with top marks, optionally hold a PhD, and be highly motivated to work on interdisciplinary research. Good knowledge of English, an open-minded spirit, being collaborative and creative are crucial.

The fellowship, which should start as soon as possible, is renewable and initially for one year. It will be commensurate to experience, can be extended depending on performance and may lead to a PhD degree. The successful candidate will be working full-time at the BioComputing UP Laboratory, University of Padova. Travel support for conferences and/or research visits abroad is provided.
To apply, please send your CV, with a motivation letter and brief description of your research background as well as the names of two (or more) references to: biocomp@bio.unipd.it.

Start date: As soon as possible

Duration: 1 year, renewable

Salary on grant: Commesurate to experience

Contact Person (Referent): Silvio Tosatto

Ref. E-Mail: biocomp@bio.unipd.it

Tel: +39 049 827 6269
Fax: +39 049 827 6260

Group Web Page: http://protein.bio.unipd.it/

Research opening @ IBAB, Bengaluru

Mon, 28 Jan 2019 17:45:54 -0600

Applications are invited for the position of Project Assistant in Bio-IT centre at IBAB, Electronic city, Bengaluru. The successful candidate will work in the next-generation sequencing (NGS) facility to perform nucleic acid isolations, quality and quantity analyses, NGS library preparations, and maintenance of sequencing related instruments and other related lab equipment. In addition, the candidate is expected to assist in various administrative matters including procurement, maintaining inventory of laboratory consumables etc. The person will have opportunity to get expertise in entire pipeline of NGS. After sufficient training, the person will act as a demonstrator in the workshops conducted by Bio-IT centre.
Essential Qualifications, Experiences, and Skills:

1. MSc. or B. Tech. or equivalent degree in Biotechnology or related life sciences discipline.
2. Strong aptitude for laboratory work and should be detail-oriented person.
3. Hands-on experience in basic molecular biology techniques.
4. Prior experience in working in a research laboratory or industry.
5. Basic IT skills that include familiarity with Microsoft Office packages.
6. Ability to carry out basic maintenance of general lab equipments and laboratory resources.
7. Ability to maintain accurate records of laboratory work.
8. Willingness to learn, and should be a team player.
Desirable Experience and Skills:
1. Familiarity with NGS technology.
2. Experience in preparation of NGS libraries.
3. Familiarity with Sanger sequencing technology (capillary electrophoresis based)

Remuneration: Remuneration will commensurate with expertise and experience.

How to Apply: Interested applicants fulfilling the criteria may send their detailed CV and a cover letter that explains their suitability for this position, in a single PDF, to Dr. Sreekanth Reddy at careers_bioit@ibab.ac.in. Last date for submission of application is 23rd February 2019. Please mention the position applying for in the subject line of the email.

About IBAB: The Bio-IT Centre at IBAB has state-of-art sequencing facility with the HiSeq 2500 and accessories such as Qubit, Covaris, Agilent 2200 TapeStation, Stratagene Mx 3000 for next generation sequencing, 3500 Dx Genetic Analyzer for capillary electrophoresis based sequencing, and HiScan for microarray imaging. The facility is fully operational and providing services to the scientific community. The Institute of Bioinformatics and Applied Biotechnology (IBAB) is a unique institute engaged in education, research and entrepreneur support programs and is based at Electronic City, Bangalore. IBAB’s mission is to catalyze the growth of the biotechnology and bioinformatics industries in India. To know more please visit: http://www.ibab.ac.in/index.php/bioit/

LAST

Archana Malhotra — Wed, 09 Mar 2016 14:27:01 -0600

LAST can:

Handle big sequence data, e.g:
- Compare two vertebrate genomes
- Align billions of DNA reads to a genome
Indicate the reliability of each aligned column.
Use sequence quality data properly.
Compare DNA to proteins, with frameshifts.
Compare PSSMs to sequences
Calculate the likelihood of chance similarities between random sequences.
Do split and spliced alignment.
Train alignment parameters for unusual kinds of sequence (e.g. nanopore).

Address of the bookmark: http://last.cbrc.jp/

Scientist-B (Bioinformatics) at AIIMS, Delhi

Sun, 20 Dec 2020 04:34:55 -0600

Name of the Project: “Artificial intelligence in Oncology, Harnessing big data and advanced computing to provide personalized diagnosis and treatment for Cancer patients”

Age Limit: 35

How to Apply for the AIIMS Life Science Job:

Interested applicants are asked to send out a detailed CV to Dr Ashok Sharma (aioncoaiims@gmail.com). Laboratory of Chromatin and also Cancer Epigenetics, Department of Biochemistry with the subject line “Application for Scientist-B position for MeitY project” latest by January 01st, 2021.
Complete Information of the year of passing, experience, marks, etc. ought to be mentioned in the CV Incomplete. applications will certainly be rejected Just shortlisted applicants will be called for interview. Chosen candidates will certainly be intimated by email/phone.
No TA/DA will certainly be paid for appearing in the interview.
Note, The institute reserved the right to fill up or not to fill up the post advertised.

Emoluments: Rs. 56,000/- plus 24 percent HRA

Eligibility:
2nd class Master’s Degree with a PhD in a pertinent subject (Bioinformatics) from.a recognized University
1st class Master’s degree in Life Sciences (Bioinformatics) from a recognized university OR.
Bachelor’s Degree in Engineering or-Technology with minimal 60% marks from a recognized University or equivalent.

Desirable Qualifications:
Experience in Bioinformatics/NGS data. Analysis/System Biology/Computer Science/ statistics with experience in Machine learning/Al project.
Experience of Deep learning applications in biological data ( image/text).
Proficient in Rf Python machine learning libraries.
Prior experience in the cancer-related project (ML-based) will be advantageous.
Experience with PyTorch/TensorFlow will certainly be very desirable.
Applicant should have strong scientific writing as well as. verbal abilities.
Papers in sci-indexed journals demonstrating ML skill sets.
Database handling will certainly be plus yet not required.

More detail at https://www.aiims.edu/images/pdf/recruitment/advertisement/biochem-16-12-20.pdf