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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/32011?offset=1300</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/36405/earth-biogenome-project</guid>
	<pubDate>Wed, 25 Apr 2018 07:48:56 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/36405/earth-biogenome-project</link>
	<title><![CDATA[Earth BioGenome Project]]></title>
	<description><![CDATA[<p><span>The central goal of the Earth BioGenome Project is to understand the evolution and organization of life on our planet by sequencing and functionally annotating the genomes of 1.5 million known species of eukaryotes, a massive group that includes plants, animals, fungi and other organisms whose cells have a nucleus that houses their chromosomal DNA. To date, the genomes of less than 0.2 percent of eukaryotic species have been sequenced.&nbsp;</span></p><p><span>More at&nbsp;https://www.ucdavis.edu/news/earth-biogenome-project-aims-sequence-dna-all-complex-life</span></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/17505/kau-thrissur-biotechbioinformatics-rasrfjrftraineestudentships</guid>
  <pubDate>Fri, 26 Sep 2014 20:07:28 -0500</pubDate>
  <link></link>
  <title><![CDATA[KAU Thrissur Biotech/Bioinformatics RA/SRF/JRF/Trainee/Studentships]]></title>
  <description><![CDATA[
<p>Applications are invited from eligible candidates for the following posts at Bioinformatics Centre (DIC), IT- BT Complex, College of Horticulture, Kerala Agricultural University, Vellanikkara, Thrissur.</p>

<p>1. Research Associate <br />Emoluments*: 14880/- + HRA 	<br />Qualification needed: Ph.D/M.Sc in Bioinformatics or Ph.D/M.Sc in Agriculture or Biotechnology with advanced Diploma in Bioinformatics <br />Desirable: 2 year experience in Bioinformatics.</p>

<p>2 Senior Research Fellow <br />Emoluments*: 10230/- 	<br />Qualification needed: M.Sc/ M.tech in Bioinformatics or M.Sc in Agriculture/ Biotechnology with Diploma in Bioinformatics. <br />Desirable: One year experience in Bioinformatics</p>

<p>3 Junior Research Fellow <br />Emoluments*: 9300/- 	<br />Qualification needed: M.Sc/ M.tech in Bioinformatics or M.Sc in Agriculture/Biotechnology/Plant Sciences with Diploma in Bioinformatics.</p>

<p>4 .Trainee/Studentship Bioinformatics <br />Emoluments*: 5000/- 	<br />Qualification needed: M.Sc in Bioinformatics with good knowledge of Bioinformatics softwares and tools.</p>

<p>5 Trainee/ Studentship Biotechnology <br />Emoluments*: 5000/- 	<br />Qualification needed: M.Sc in Biotechnology, with working knowledge in tissue culture, molecular markers and cloning of genes.</p>

<p>Candidates with the required qualifications and experience may give an application in the prescribed format with attested copies of certificates to prove eligibility on or before 30th November 2014. The applications are to be addressed to The Associate Dean, College of Horticulture and send to "Professor &amp; Coordinator, Bioinformatics Centre (DIC), IT-BT Complex, Kerala Agricultural University, Vellanikkara, Thrissur, Kerala 680 656”. The envelope may be superscribed “Application for the post at Bioinformatics Centre”.</p>

<p>*Emoluments are likely to be revised in 2014-2015</p>

<p>More at http://www.kaubic.in/downloads/Notification_bic.pdf<br />http://www.kaubic.in/downloads/Application%20form.pdf</p>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44635/1000-genomes-chile-project</guid>
	<pubDate>Thu, 08 Aug 2024 01:24:13 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44635/1000-genomes-chile-project</link>
	<title><![CDATA[1000 Genomes Chile Project]]></title>
	<description><![CDATA[<p>Welcome to Chile Sequence to Chile: A Genomic Exploration Project for the Future Genomics, the science that deciphers the complexity of DNA, immerses us in the world of life at its most basic level. On this journey into the depths of genetic information, we find the 1000 Genomes Chile Project, an initiative that seeks to explore and understand the genetic wealth of our country.</p>
<p>Deciphering Life at the Molecular Level DNA sequencing is the key that opens the door to invaluable knowledge. By understanding the genes that make up Chilean species, we unravel the secrets of their evolution, their resistance and their adaptation to the environment. In a world where biodiversity faces constant threats, sequencing becomes crucial for the conservation and understanding of our natural heritage.</p>
<p>Involving Everyone: A Nationwide Effort The 1000 Genomes Chile Project is not just a task for scientists. It is a country-wide effort that seeks the participation of everyone: from citizens to the government to the private sector. We believe in the importance of sharing knowledge, involving society in the selection of species to sequence, in monitoring progress and in applying the results to preserve our environment.</p><p>Address of the bookmark: <a href="https://1000genomas.cl/" rel="nofollow">https://1000genomas.cl/</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/17894/faculty-position-at-national-institute-of-technology-rourkela</guid>
  <pubDate>Sun, 05 Oct 2014 15:45:13 -0500</pubDate>
  <link></link>
  <title><![CDATA[FACULTY POSITION at NATIONAL INSTITUTE OF TECHNOLOGY, ROURKELA]]></title>
  <description><![CDATA[
<p>NIT, Rourkela, an institute of national importance under Ministry of HRD, Govt. of India invites applications from Indian nationals possessing excellent academic background along with commitment to quality teaching and research for faculty positions at the level of Professor, Associate Professor and Assistant Professor in most branches of Engineering, Science, Management and Humanities as per following table:-</p>

<p>    1 Asst. Professor (on Pre-Ph.D. Contract)</p>

<p>    2 Asst. Professor (on Contract)</p>

<p>    3 Asst. Professor</p>

<p>    4 Associate Professor</p>

<p>    5 Professor</p>

<p>Life Sciences:-</p>

<p>    i)Biochemistry and Molecular Biology; ii)Cell and Developmental Biology; iii)Immunology and Molecular Medicine; (iv) Microbiology and Ecology (v)Bioinformatics Group; vi)Biophysical Sciences</p>

<p>HOW TO APPLY:-</p>

<p>a. Candidates willing to apply for one or more posts are requested to apply online at “http://www.nitrkl.ac.in/ JOBS &amp; TENDERS /Faculty Position” .<br />b. Persons employed in Government and Semi-Government organizations may apply directly against the standing advertisement. For this the application should be completed online. The printout of the application generated online should be submitted through employer if shortlisted for interview.<br />c. The online application can be filled in multiple sessions.<br />d. Candidates are required to check the Institute website from time to time for latest information, application status call for interview, change of dates and final results.<br />e. Applications shall be received online only. Please do not send application or CV against this advertisement by email or letter mail.</p>

<p>More Info: http://nitrkl.ac.in/Jobs_Tenders/1FacultyPosition/Default.aspx</p>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42572/the-breeding-api-brapi-project</guid>
	<pubDate>Wed, 06 Jan 2021 19:51:17 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42572/the-breeding-api-brapi-project</link>
	<title><![CDATA[The Breeding API (BrAPI) project]]></title>
	<description><![CDATA[<p><span>The Breeding API (BrAPI) project is an effort to enable interoperability among plant breeding databases. BrAPI is a standardized RESTful web service API specification for communicating plant breeding data. This community driven standard is free to be used by anyone interested in plant breeding data management.</span></p><p>Address of the bookmark: <a href="https://brapi.org/" rel="nofollow">https://brapi.org/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/17924/software-developed-in-pevsner-lab</guid>
	<pubDate>Mon, 06 Oct 2014 12:41:26 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/17924/software-developed-in-pevsner-lab</link>
	<title><![CDATA[Software developed in pevsner lab]]></title>
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<p><a href="http://pevsnerlab.kennedykrieger.org/dragon.htm">DRAGON</a>: Database Referencing of Array Genes Online</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/96">SNOMAD</a>: Standardization and Normalization of Microarray Data</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/70">SNPduo</a>: SNP Analysis Between Two Individuals</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/71">SNPtrio</a>: Analyzing and Visualizing and Inheritance Patterns in Trios</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/64">SNPscan</a>: Data Analysis and Visualization of SNP Data</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/64">pediSNP</a>: Analyze SNP Data From a Pedigree of Two Generations</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/73">kcoeff</a>: Calculate Cotterman Coefficients of SNP Genotype Data</p>
<p><a href="http://pevsnerlab.kennedykrieger.org/php/node/113">triPOD:</a> Detects chromosomal abnormalities in parent-child trio-based microarray data</p>
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</div><p>Address of the bookmark: <a href="http://pevsnerlab.kennedykrieger.org/php/?q=software" rel="nofollow">http://pevsnerlab.kennedykrieger.org/php/?q=software</a></p>]]></description>
	<dc:creator>Robert M Willioms</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/3965/ruby-and-bioruby-tutorials</guid>
	<pubDate>Mon, 26 Aug 2013 17:18:28 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/3965/ruby-and-bioruby-tutorials</link>
	<title><![CDATA[Ruby and BioRuby Tutorials]]></title>
	<description><![CDATA[<p>Collections of Ruby and BioRuby learning materials.</p>
<p>BioRuby paper link :&nbsp;<a href="http://bioinformatics.oxfordjournals.org/content/26/20/2617.abstract">http://bioinformatics.oxfordjournals.org/content/26/20/2617.abstract</a></p><p>Address of the bookmark: <a href="http://www.codeschool.com/paths/ruby" rel="nofollow">http://www.codeschool.com/paths/ruby</a></p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/22318/research-fellows-at-csir-institute-of-himalayan-bioresource-technology-palampur-himachal-pradesh</guid>
  <pubDate>Tue, 19 May 2015 07:17:32 -0500</pubDate>
  <link></link>
  <title><![CDATA[Research Fellows at  CSIR - Institute of Himalayan Bioresource Technology, Palampur, Himachal Pradesh]]></title>
  <description><![CDATA[
<p>CSIR - Institute of Himalayan Bioresource Technology 2 vacancies of Project Fellow</p>

<p>Name of the Post: Project Fellow</p>

<p>No. of the Post: 02 Two</p>

<p>Salary: Rs. 12000/- per month or Rs. 14000/- per month</p>

<p>Age Limit: Max. 28 years as on 10.06.2015 and relaxation as per rules</p>

<p>Required Job Profile:</p>

<p>Candidate must possess first class B.Tech. in bioinformatics or computational biology OR M.Sc. in bioinformatics or computational biology with fifty five percent marks OR M.Tech. in bioinformatics or computational biology with fifty five percent marks.</p>

<p>How to apply:</p>

<p>Eligible and interested candidates should need to appear for walk-in interview on 10.06.2015 at 9:00 am at the above mentioned address.</p>

<p>Refer to http://www.ihbt.res.in/recruit/AdvtNo7_2015.pdf</p>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44865/snp-analysis-unlocking-the-secrets-in-our-dna</guid>
	<pubDate>Wed, 16 Jul 2025 01:31:45 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44865/snp-analysis-unlocking-the-secrets-in-our-dna</link>
	<title><![CDATA[SNP Analysis: Unlocking the Secrets in Our DNA]]></title>
	<description><![CDATA[<p>Single Nucleotide Polymorphisms (SNPs) are the most common type of genetic variation in humans&mdash;and many other organisms. A single base change in the DNA sequence (for example, an A instead of a G) can influence everything from our eye color to our risk of developing diseases. Analyzing these tiny changes has become central to modern genetics, medicine, agriculture, and evolutionary biology.</p><p><strong>What are SNPs?</strong><br />SNPs (pronounced "snips") are positions in the genome where individuals differ by a single nucleotide. For example:</p><p>Reference: ...A T G C A T G A...<br />Variant:&nbsp; &nbsp; &nbsp;...A T G T A T G A...</p><p>Here, the C in the reference genome has been replaced by a T in the variant.</p><p>SNPs occur roughly every 300&ndash;1,000 bases in the human genome, meaning there are millions of them scattered throughout our DNA. Most SNPs have no effect on health, but some are linked to disease susceptibility, drug response, and other traits.</p><p><strong>Why Do We Analyze SNPs?</strong><br />1. Medical Genetics</p><p>Identify disease-associated variants (e.g., BRCA1/2 in breast cancer).</p><p>Predict drug response (pharmacogenomics).</p><p>Enable precision medicine by tailoring treatments.</p><p>2. Population Genetics &amp; Ancestry</p><p>Trace human migration and ancestry.</p><p>Study genetic diversity within and between populations.</p><p>3. Agriculture &amp; Animal Breeding</p><p>Select for desirable traits (drought resistance, yield, disease resistance).</p><p>Improve breeding efficiency in livestock.</p><p>4. Evolutionary Biology</p><p>Track natural selection.</p><p>Study adaptation in wild populations.</p><p><strong>How is SNP Analysis Performed?</strong><br />SNP analysis can be broadly divided into three steps:</p><p>SNP Detection<br />Genotyping arrays: Chips that test hundreds of thousands of known SNP positions simultaneously. Fast and affordable, widely used in consumer ancestry testing.</p><p>Whole-genome or whole-exome sequencing: Can detect known and novel SNPs across the genome.</p><p>Targeted sequencing or PCR: For focused analysis of specific regions.</p><p>Variant Calling<br />Sequencing data is aligned to a reference genome. Bioinformatics tools (e.g., GATK, bcftools) identify positions where the sequenced sample differs from the reference.</p><p>Annotation and Interpretation<br />Tools (e.g., SnpEff, VEP) predict the functional impact of SNPs.</p><p>Are the SNPs in coding regions? Do they cause amino acid changes? Are they known to be pathogenic?</p><p>Databases like dbSNP, ClinVar, and GWAS Catalog provide information on known associations.</p><p>Common Tools for SNP Analysis<br />Alignment: BWA, Bowtie2</p><p>Variant Calling: GATK, FreeBayes</p><p>Visualization: IGV, UCSC Genome Browser</p><p>Annotation: SnpEff, VEP</p><p>Statistical Analysis: PLINK, SNPTEST</p><p><strong>Challenges in SNP Analysis</strong><br />False positives/negatives: Sequencing errors, alignment issues.</p><p>Population stratification: Confounding in association studies.</p><p>Interpretation: Many SNPs have unknown or complex effects.</p><p>Researchers address these with rigorous quality control, large datasets, and increasingly sophisticated statistical models.</p><p><strong>The Future of SNP Analysis</strong><br />With advances in sequencing technology and AI-driven analysis, SNP studies are expanding:</p><p>Polygenic risk scores predict disease risk based on thousands of SNPs.</p><p>Large-scale biobanks (e.g., UK Biobank, All of Us) enable powerful genome-wide association studies (GWAS).</p><p>CRISPR and functional assays help validate SNP effects in the lab.</p><p>SNP analysis is at the heart of the genomic revolution, promising insights into biology, health, and evolution at unprecedented scale.</p><p><strong>Conclusion</strong><br />From diagnosing rare diseases to designing better crops, SNP analysis is a foundational tool in modern science. As our ability to sequence and interpret genomes improves, so will our understanding of these tiny&mdash;but mighty&mdash;variations in DNA.</p><p>&nbsp;</p>]]></description>
	<dc:creator>Abhi</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/18384/big-genomic-data-on-google-cloud-platform</guid>
	<pubDate>Fri, 17 Oct 2014 02:16:00 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/18384/big-genomic-data-on-google-cloud-platform</link>
	<title><![CDATA[Big genomic data on Google Cloud Platform]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/ExNxi_X4qug" frameborder="0" allowfullscreen></iframe>As the cost of DNA sequencing has dropped, the volume of data produced has risen into the petabytes. Google is working with the genomics community to define a standard API for working with big genomic data sets in the cloud. Building on Google Cloud Platform, we show how to store, process, explore and share genomic data using technologies like BigQuery, AppEngine MapReduce, R and more.]]></description>
	
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