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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/32152?offset=1060</link>
	<atom:link href="https://bioinformaticsonline.com/related/32152?offset=1060" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/34463/single-cell-rnaseq-data-analysis-tutorial</guid>
	<pubDate>Mon, 27 Nov 2017 16:24:29 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/34463/single-cell-rnaseq-data-analysis-tutorial</link>
	<title><![CDATA[Single Cell RNAseq data analysis tutorial !!]]></title>
	<description><![CDATA[<ul>
<li>A major breakthrough (replaced microarrays) in the late 00&rsquo;s and has been widely used since</li>
<li>Measures the&nbsp;average expression level&nbsp;for each gene across a large population of input cells</li>
<li>Useful for comparative transcriptomics, e.g.&nbsp;samples of the same tissue from different species</li>
<li>Useful for quantifying expression signatures from ensembles, e.g.&nbsp;in disease studies</li>
<li>Insufficient&nbsp;for studying heterogeneous systems, e.g.&nbsp;early development studies, complex tissues (brain)</li>
<li>Does&nbsp;not&nbsp;provide insights into the stochastic nature of gene expression</li>
</ul><p>Following are the useful links:</p><p><a href="http://hemberg-lab.github.io/scRNA.seq.course/scRNA-seq-course.pdf" target="_blank">Single Cell RNAseq data analysis Tutorial</a></p><p><a href="https://f1000research.com/articles/5-2122/v2" target="_blank">A step-by-step workflow for low-level analysis of single-cell RNA-seq data</a></p><p><a href="https://www.bioconductor.org/help/workflows/simpleSingleCell/" target="_blank">A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor</a></p><p>SCell: single-cell RNA-seq analysis software</p><p><a href="https://github.com/diazlab/SCell">https://github.com/diazlab/SCell</a></p><p>Beta-Poisson model for single-cell RNA-seq data analyses</p><p><a href="https://github.com/nghiavtr/BPSC">https://github.com/nghiavtr/BPSC</a></p><p>Sincera: A Computational Pipeline for Single Cell RNA-Seq Profiling Analysis</p><p><a href="https://research.cchmc.org/pbge/sincera.html">https://research.cchmc.org/pbge/sincera.html</a></p><p>SC3 &ndash; consensus clustering of single-cell RNA-Seq data</p><p><a href="http://biorxiv.org/content/early/2016/09/02/036558">http://biorxiv.org/content/early/2016/09/02/036558</a></p><p>Citrus: A toolkit for single cell sequencing analysis</p><p><a href="http://biorxiv.org/content/early/2016/09/14/045070">http://biorxiv.org/content/early/2016/09/14/045070</a></p><p>Single-Cell Resolution of Temporal Gene Expression during Heart Development</p><p><a href="http://www.cell.com/developmental-cell/fulltext/S1534-5807%2816%2930682-7">http://www.cell.com/developmental-cell/fulltext/S1534-5807(16)30682-7</a></p><p>Scalable latent-factor models applied to single-cell RNA-seq data separate biological drivers from confounding effects</p><p><a href="http://biorxiv.org/content/early/2016/11/15/087775">http://biorxiv.org/content/early/2016/11/15/087775</a></p><p>Single cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes</p><p><a href="http://genome.cshlp.org/content/early/2016/11/18/gr.212720.116.abstract">http://genome.cshlp.org/content/early/2016/11/18/gr.212720.116.abstract</a></p><p>SCODE: An efficient regulatory network inference algorithm from single-cell RNA-Seq during differentiation</p><p><a href="http://biorxiv.org/content/early/2016/11/21/088856">http://biorxiv.org/content/early/2016/11/21/088856</a></p><p>SCOUP is a probabilistic model to analyze single-cell expression data during differentiation</p><p><a href="https://github.com/hmatsu1226/SCOUP">https://github.com/hmatsu1226/SCOUP</a></p><p>scLVM is a modelling framework for single-cell RNA-seq data</p><p><a href="https://github.com/PMBio/scLVM">https://github.com/PMBio/scLVM</a></p><p>Selective Locally linear Inference of Cellular Expression Relationships (SLICER) algorithm for inferring cell trajectories</p><p><a href="https://github.com/jw156605/SLICER">https://github.com/jw156605/SLICER</a></p><p>SinQC: A Method and Tool to Control Single-cell RNA-seq Data Quality</p><p><a href="http://www.morgridge.net/SinQC.html">http://www.morgridge.net/SinQC.html</a></p><p>TSCAN: Pseudo-time reconstruction and evaluation in single-cell RNA-seq analysis</p><p><a href="https://github.com/zji90/TSCAN">https://github.com/zji90/TSCAN</a></p><p>Visualization and cellular hierarchy inference of single-cell data using SPADE</p><p><a href="http://www.nature.com/nprot/journal/v11/n7/full/nprot.2016.066.html">http://www.nature.com/nprot/journal/v11/n7/full/nprot.2016.066.html</a></p><p>OEFinder: Identify ordering effect genes in single cell RNA-seq data</p><p><a href="https://github.com/lengning/OEFinder">https://github.com/lengning/OEFinder</a></p>]]></description>
	<dc:creator>Robert M Willioms</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40235/bioinformatics-web-development-course</guid>
	<pubDate>Wed, 06 Nov 2019 20:42:48 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40235/bioinformatics-web-development-course</link>
	<title><![CDATA[Bioinformatics web development course]]></title>
	<description><![CDATA[<p>This web development course, targeted at Biology and Bioinformatics students, aims at teaching from scratch all the skills needed to setup a fully working Linux web server and to develop and deploy web applications for Bioinformatics.</p>
<p>No previous programming knowledge is assumed. By following this tutorial you will learn the fundamental concepts of programming by using scripting languages: variables, types, arrays, cycles, conditional statements, functions, objects, regular expressions, files reading and manipulation et-cetera.</p><p>Address of the bookmark: <a href="http://www.cellbiol.com/bioinformatics_web_development/introduction/" rel="nofollow">http://www.cellbiol.com/bioinformatics_web_development/introduction/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34715/delta-a-new-web-based-3d-genome-visualization-and-analysis-platform</guid>
	<pubDate>Wed, 20 Dec 2017 08:49:55 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34715/delta-a-new-web-based-3d-genome-visualization-and-analysis-platform</link>
	<title><![CDATA[Delta: a new Web-based 3D genome visualization and analysis platform]]></title>
	<description><![CDATA[<p><em>Delta</em><span>&nbsp;is an integrative visualization and analysis platform to facilitate visually annotating and exploring the 3D physical architecture of genomes.&nbsp;</span><em>Delta</em><span>&nbsp;takes Hi-C or ChIA-PET contact matrix as input and predicts the topologically associating domains and chromatin loops in the genome. It then generates a physical 3D model which represents the plausible consensus 3D structure of the genome.&nbsp;</span><em>Delta</em><span>features a highly interactive visualization tool which enhances the integration of genome topology/physical structure with extensive genome annotation by juxtaposing the 3D model with diverse genomic assay outputs.</span></p>
<p>https://github.com/zhangzhwlab/delta</p><p>Address of the bookmark: <a href="https://github.com/zhangzhwlab/delta" rel="nofollow">https://github.com/zhangzhwlab/delta</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/40945/the-clark-lab</guid>
  <pubDate>Fri, 07 Feb 2020 13:57:24 -0600</pubDate>
  <link></link>
  <title><![CDATA[The Clark Lab]]></title>
  <description><![CDATA[
<p>Study the process of Adaptive Evolution, during which species adopt novel traits to overcome challenges. We retrace the evolutionary histories of genomic elements to determine the changes underlying adaptation and to discover previously unknown genetic networks. These discoveries have already led to advances in human health, species conservation, and molecular biology. </p>

<p>More at http://clark.genetics.utah.edu/</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/35384/mgcv-the-microbial-genomic-context-viewer-for-comparative-genome-analysis</guid>
	<pubDate>Mon, 29 Jan 2018 04:55:46 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/35384/mgcv-the-microbial-genomic-context-viewer-for-comparative-genome-analysis</link>
	<title><![CDATA[MGcV: the microbial genomic context viewer for comparative genome analysis]]></title>
	<description><![CDATA[<p><span>MGcV is an interactive web-based visalization tool tailored to facilitate small scale genome analysis. To start using MGcV:</span></p>
<ol>
<li>Supply your genes/genomic segments/phylogenetic tree of interest in the input-box by
<ul>
<li>selecting the type of identifier and pasting identifiers (one per line)</li>
<li><em><strong>or</strong></em>&nbsp;by using the&nbsp;<a>gene ID search tool</a></li>
<li><em><strong>or</strong></em>&nbsp;with the&nbsp;<a>BLAST search tool</a></li>
</ul>
</li>
<li>Click "Visualize context".</li>
</ol>
<p><span>Consult the&nbsp;</span><a href="http://mgcv.cmbi.ru.nl/help.html" target="_blank">documentation</a><span>&nbsp;to learn more about MGcV.</span></p><p>Address of the bookmark: <a href="http://mgcv.cmbi.ru.nl/" rel="nofollow">http://mgcv.cmbi.ru.nl/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37239/kat-a-k-mer-analysis-toolkit-to-quality-control-ngs-datasets-and-genome-assemblies</guid>
	<pubDate>Fri, 06 Jul 2018 03:36:45 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37239/kat-a-k-mer-analysis-toolkit-to-quality-control-ngs-datasets-and-genome-assemblies</link>
	<title><![CDATA[KAT: a K-mer analysis toolkit to quality control NGS datasets and genome assemblies]]></title>
	<description><![CDATA[<p>KAT is a suite of tools that analyse jellyfish hashes or sequence files (fasta or fastq) using kmer counts. The following tools are currently available in KAT:</p>
<ul>
<li><span>hist</span>: Create an histogram of k-mer occurrences from a sequence file. Adds metadata in output for easy plotting.</li>
<li><span>gcp:</span>&nbsp;K-mer GC Processor. Creates a matrix of the number of K-mers found given a GC count and a K-mer count.</li>
<li><span>comp</span>: K-mer comparison tool. Creates a matrix of shared K-mers between two (or three) sequence files or hashes.</li>
<li><span>sect</span>: SEquence Coverage estimator Tool. Estimates the coverage of each sequence in a file using K-mers from another sequence file.</li>
<li><span>blob</span>: Given, reads and an assembly, calculates both the read and assembly K-mer coverage along with GC% for each sequence in the assembly.SEquence Coverage estimator Tool.</li>
<li><span>filter</span>: Filtering tools. Contains tools for filtering k-mer hashes and FastQ/A files:
<ul>
<li><span>kmer</span>: Produces a k-mer hash containing only k-mers within specified coverage and GC tolerances.</li>
<li><span>seq</span>: Filters a sequence file based on whether or not the sequences contain k-mers within a provided hash.</li>
</ul>
</li>
<li><span>plot</span>: Plotting tools. Contains several plotting tools to visualise K-mer and compare distributions. The following plot tools are available:
<ul>
<li><span>density</span>: Creates a density plot from a matrix created with the "comp" tool. Typically this is used to compare two K-mer hashes produced by different NGS reads.</li>
<li><span>profile</span>: Creates a K-mer coverage plot for a single sequence. Takes in fasta coverage output coverage from the "sect" tool</li>
<li><span>spectra-cn</span>: Creates a stacked histogram using a matrix created with the "comp" tool. Typically this is used to compare a jellyfish hash produced from a read set to a jellyfish hash produced from an assembly. The plot shows the amount of distinct K-mers absent, as well as the copy number variation present within the assembly.</li>
<li><span>spectra-hist</span>: Creates a K-mer spectra plot for a set of K-mer histograms produced either by jellyfish-histo or kat-histo.</li>
<li><span>spectra-mx</span>: Creates a K-mer spectra plot for a set of K-mer histograms that are derived from selected rows or columns in a matrix produced by the "comp".</li>
</ul>
</li>
</ul>
<p>In addition, KAT contains a python script for analysing the mathematical distributions present in the K-mer spectra in order to determine how much content is present in each peak.</p>
<p>This README only contains some brief details of how to install and use KAT. For more extensive documentation please visit:&nbsp;<a href="https://kat.readthedocs.org/en/latest/">https://kat.readthedocs.org/en/latest/</a></p>
<p><a href="https://academic.oup.com/bioinformatics/article/33/4/574/2664339">https://academic.oup.com/bioinformatics/article/33/4/574/2664339&nbsp;</a></p><p>Address of the bookmark: <a href="https://github.com/TGAC/KAT" rel="nofollow">https://github.com/TGAC/KAT</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/42165/bioinformatics-scientistresearch-software-engineer-at-university-of-dundee-dundee-united-kingdom</guid>
  <pubDate>Wed, 26 Aug 2020 10:31:25 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics Scientist/Research Software Engineer at University of Dundee Dundee, United Kingdom]]></title>
  <description><![CDATA[
<p>We are recruiting for an exceptional individual to join us as a computational scientist, bioinformatician, or (research) software engineer with an interest in interactive data analysis platforms for biology and medicine within our Jalview (www.jalview.org) research software engineering team.</p>

<p>More at https://www.jobs.dundee.ac.uk/fe/tpl_uod01.asp?s=4A515F4E5A565B1A&amp;jobid=104342,2382988671&amp;key=147934117&amp;c=99413415238921&amp;pagestamp=sesxbbuyifokdsfygf</p>

<p>Last date: 30th August 2020</p>

<p>Informal enquiries about this position may be made to Prof. Geoff Barton (gjbarton@dundee.ac.uk) or Dr Jim Procter (jprocter@dundee.ac.uk). To find out more about Jalview research software engineering team please visit www.jalview.org and www.compbio.dundee.ac.uk</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40611/deepvariant-an-analysis-pipeline-that-uses-a-deep-neural-network-to-call-genetic-variants-from-next-generation-dna-sequencing-data</guid>
	<pubDate>Sat, 25 Jan 2020 13:28:09 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40611/deepvariant-an-analysis-pipeline-that-uses-a-deep-neural-network-to-call-genetic-variants-from-next-generation-dna-sequencing-data</link>
	<title><![CDATA[DeepVariant : an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.]]></title>
	<description><![CDATA[<p><span>DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data.</span></p>
<p><span><span>DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants from next-generation DNA sequencing data. DeepVariant relies on&nbsp;</span><a href="https://github.com/google/nucleus">Nucleus</a><span>, a library of Python and C++ code for reading and writing data in common genomics file formats (like SAM and VCF) designed for painless integration with the&nbsp;</span><a href="https://www.tensorflow.org/">TensorFlow</a><span>&nbsp;machine learning framework.</span></span></p>
<p><span><a href="https://ai.googleblog.com/2017/12/deepvariant-highly-accurate-genomes.html">https://ai.googleblog.com/2017/12/deepvariant-highly-accurate-genomes.html</a></span></p>
<p><span><a href="https://www.biorxiv.org/content/10.1101/092890v6">https://www.biorxiv.org/content/10.1101/092890v6</a></span></p>
<p><span><img src="https://4.bp.blogspot.com/-2KlXZO60sWE/WiGc8qlZfxI/AAAAAAAACOs/s1pNiKI8jsAvJLr1E_po5udDO8eObm_awCLcBGAs/s640/image3.png" width="640" height="427" alt="image" style="border: 0px;"></span></p><p>Address of the bookmark: <a href="https://github.com/google/deepvariant" rel="nofollow">https://github.com/google/deepvariant</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/42227/two-faculty-positions-at-national-taiwan-university-taipei-taiwan</guid>
  <pubDate>Thu, 22 Oct 2020 04:53:12 -0500</pubDate>
  <link></link>
  <title><![CDATA[Two Faculty Positions at National Taiwan University, Taipei, Taiwan]]></title>
  <description><![CDATA[
<p>The Department of Agronomy at National Taiwan University, Taipei, Taiwan,<br />invites applications for two full-time faculty positions beginning August<br />1, 2021 at the rank of Assistant Professor, Associate Professor or<br />Professor in Biometry and Bioinformatics and Plant Breeding and Genetics,<br />respectively.</p>

<p>A qualified candidate should hold a Ph.D. in a relevant field including<br />Agronomy, Statistics, Bioinformatics, Plant Breeding, Plant Genetics or<br />Quantitative Genetics. For the position in Biometry and Bioinformatics, the<br />applicants capable of teaching fundamental statistics/bioinformatics<br />courses or with experience in crop science are preferable; for Plant<br />Breeding and Genetics, the applicants capable of teaching fundamental plant<br />breeding courses, with experience in crop breeding, or training in<br />quantitative genetics are preferred.</p>

<p>The application package should include two letters of reference and five<br />printed copies of the following documents (1) curriculum vitae, (2)<br />publication list, (3) undergraduate and graduate transcripts if applying<br />for the Assistant Professorship, (4) a photocopy of the Ph.D. diploma, (5)<br />teaching plan and course outline or syllabus (6) research proposal, (7) a<br />cover letter indicating the rank to apply, and one representative original<br />research article which was published by the applicant being the 1st or<br />corresponding author in an SCI peer-reviewed journal within 5 years (after<br />August 1, 2016); a copy of doctoral dissertation can be the representative<br />article if applying for the Assistant Professorship; (8) reprints of the<br />selected publications published within 7 years (after August 1, 2014).</p>

<p>The application package should mail to the Chair, Dr. Li-yu Daisy Liu<br />(lyliu@ntu.edu.tw), in the Department of Agronomy, National Taiwan<br />University, No. 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan, before<br />December 15, 2020 for full consideration.</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41209/juicebox-visualization-and-analysis-software-for-hi-c-data</guid>
	<pubDate>Fri, 21 Feb 2020 00:33:38 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41209/juicebox-visualization-and-analysis-software-for-hi-c-data</link>
	<title><![CDATA[Juicebox: Visualization and analysis software for Hi-C data]]></title>
	<description><![CDATA[<p>Juicebox is visualization software for Hi-C data. This distribution includes the source code for Juicebox,&nbsp;<a href="https://github.com/theaidenlab/juicer/wiki/Download">Juicer Tools</a>, and&nbsp;<a href="https://aidenlab.org/assembly/">Assembly Tools</a>.&nbsp;<a href="https://github.com/theaidenlab/juicebox/wiki/Download">Download Juicebox here</a>, or use&nbsp;<a href="https://aidenlab.org/juicebox">Juicebox on the web</a>. Detailed documentation is available&nbsp;<a href="https://github.com/theaidenlab/juicebox/wiki">on the wiki</a>. Instructions below pertain primarily to usage of command line tools and the Juicebox jar files.</p>
<p>Juicebox can now be used to visualize and interactively (re)assemble genomes. Check out the Juicebox Assembly Tools Module website&nbsp;<a href="https://aidenlab.org/assembly">https://aidenlab.org/assembly</a>&nbsp;for more details on how to use Juicebox for assembly.</p>
<p>GUI at&nbsp;<a href="https://aidenlab.org/juicebox/">https://aidenlab.org/juicebox/</a></p><p>Address of the bookmark: <a href="https://github.com/aidenlab/Juicebox" rel="nofollow">https://github.com/aidenlab/Juicebox</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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