BOL: Related items

Dahak: benchmarking and containerization of tools for analysis of complex non-clinical metagenomes.

BioStar — Thu, 09 Apr 2020 04:56:09 -0500

Dahak is a software suite that integrates state-of-the-art open source tools for metagenomic analyses. Tools in the dahak software suite will perform various steps in metagenomic analysis workflows including data pre-processing, metagenome assembly, taxonomic and functional classification, genome binning, and gene assignment. We aim to deliver the analytical framework as a robust and reliable containerized workflow system, which will be free from dependency, installation, and execution problems typically associated with other open-source bioinformatics solutions. This will maximize the transparency, data provenance (i.e., the process of tracing the origins of data and its movement through the workflow), and reproducibility.

More at https://dahak-metagenomics.github.io/dahak/

Address of the bookmark: https://github.com/dahak-metagenomics/dahak

Two postdoc positions to study multiscale genome evolution and cephalopod gene regulation (University of Vienna, Austria)

Thu, 17 Dec 2020 11:45:16 -0600

Vienna Biocenter are seeking two postdoctoral researchers to join our team and work on the ERC funded project "METASCALE: Modes of genome evolution during major metazoan transitions". The task of both positions will be to study co-evolutionary trends within animal genomes and their association with the emergence of new gene regulation. Our group employs methods of comparative and regulatory genomics to study the regulatory impact of transitions in animal genome architecture. More recently, we have identified a major genome reorganization in the "smart" coleoid cephalopod molluscs (squid, octopus, cuttlefish) that, together with other genomic changes, potentially comprises a unique path or mode of genome evolution among animals. We are thus interested in quantifying these modes of genome evolution across all available animal genomes and to test whether their shifts are associated with the emergence of novel regulation (e.g., in cephalopods). One of our main model species is the Hawaiian bobtail squid species Euprymna scolopes. The tasks of the two candidates will be complimentary and highly collaborative with one position focusing on comparative genomics analyses across all metazoans and the other position on regulatory genomics in the squid. A solid background in in bioinformatics and comparative genomics is highly desired for the first position, whereas the second position will benefit from experience in molecular and regulatory genomics methods such as HiC, ATAC-seq, RNA-seq or single cell transcriptomics.

The postdocs will join an international group and network of researchers at the University of Vienna studying a diverse range of species and questions in molecular evolution, development, morphology and genomics. Our group is also part of the large evolVienna network of more than 50 evolutionary biology labs in Vienna, across several universities and research institutes. Our Faculty will be relocating to a new campus at the Vienna Biocenter in summer 2021 (https://biologiezentrum.univie.ac.at/en/). Vienna is a vibrant historic European capital with a high QOL. Information about postdoctoral salaries in Austria can be found on this webpage: https://www.fwf.ac.at/en/research-funding/personnel-costs/

Earliest start date will be after July 2021. Initial term of employment is for two years with the possibility of extension. Remote working, at least initially, is a possibility.

Requirements:
- PhD degree or equivalent by the start date
- Publishing record in peer-reviewed journals or evidence thereof
- At least 2 letters of support

Applications including a letter of motivation should be submitted via the Job Center to the University of Vienna (https://personalwesen.univie.ac.at/en/jobs-recruiting/job-center/,
job reference number 11615).

Application deadline: January 15th 2021.
Application link: https://univis.univie.ac.at/ebewerbung

DnaSP: DNA Sequence Polymorphism, is a software package for the analysis of DNA polymorphisms

Neel — Wed, 25 Nov 2020 19:51:38 -0600

DnaSP, DNA Sequence Polymorphism, is a software package for the analysis of DNA polymorphisms using data from a single locus (a multiple sequence aligned -MSA data), or from several loci (a Multiple-MSA data, such as formats generated by some assembler RAD-seq software). DnaSP can estimate several measures of DNA sequence variation within and between populations in noncoding, synonymous or nonsynonymous sites, or in various sorts of codon positions), as well as linkage disequilibrium, recombination, gene flow and gene conversion parameters.

Address of the bookmark: http://www.ub.edu/dnasp/

Bioinformatics in Africa:- Part 1

BioStar — Sun, 31 Jan 2021 09:04:01 -0600

The Institut Pasteur de Côte d’Ivoire was created by the N°72511 law of July 27th, 1972 under the Presidency of his Excellency Felix Houphouët Boigny and Professor Jacques Monod, then Leading of the Pasteur institute of Paris.

The objectives of the Bioinformatics pole are:

• Encourage the access to innovations in research and the best exploitation of research data management.

• Develop the critical spirit of the researchers around their axis of research.

• Bring an active help to the improvement of the public health while having for constant worries to feed it by research and the innovation.

• Start training researchers to use bioinformatics as an indispensable tool to research.

• Encourage interdisciplinary creating a network of scientific information available to the researchers of the institute and partners

Longterm training activities:

• To integrate the bioinformatics in the training programs of academic scientists.

• Development of West Africa Centre training in bioinformatics and genome data analysis.

Shortterm training activities:

The IPCI will organize in the month of May 2007 a yearly regional course of initiation and using genome data analysis with the participation of the Centre Biotechnologique de Sfax, Tunisia (Pr Ahmed Rebaï, Department of bioinformatics).

More at https://www.pasteur.ci/

GenomeTools: The versatile open source genome analysis software

Neel — Wed, 02 Feb 2022 04:00:21 -0600

The GenomeTools genome analysis system is a free collection of bioinformatics tools (in the realm of genome informatics) combined into a single binary named gt. It is based on a C library named “libgenometools” which consists of several modules.

If you are interested in gene prediction, have a look at GenomeThreader.

http://genometools.org/pub/

Address of the bookmark: http://genometools.org/

Bioinformatics in Africa: Part5 - Nigeria

BioStar — Sat, 06 Feb 2021 21:13:47 -0600

Covenant University (CU)Ota:
Covenant University (with her enriching and growing stateoftheart laboratories in the area of science and technology, arts, business and social sciences) is presently the Best University in Nigeria (Private University category), based on the recent overall rating just concluded by the Nigeria University Commission (NUC). Recently, Covenant University has initiated the establishment of a Centre for Applied Biotech, BioInformatics and Microbiology (CBBM) to be situated at the University. The institute has been designed to be a PublicPrivate Partnership for a productive synergy b/w Academia, Industry and Government. The whole concept is still evolving and more details will be release soon. As regards CBBM, a dedicated computing lab is in plan, but even our computing capacity is presently enormous. In the department of Computer and Information Sciences, we have more than 250 Pentium 4 PCs set aside for teaching and research purposes. Furthermore, we have several moderate speed PCs at the Postgraduate research lab and our engineering departments and units. Our wet lab facilities is presently minimal (basic for teaching), the Centre requirement as it touches the wetlaboratories is also set to upgrade this to basic tools expected at an international centre of learning.

University of Ibadan (UIB)Ibadan:
There has been significant increase in the number of bioinformatics activities in Nigeria (and West Africa) since 2003 when the program was initiated by the West African Biotechnology Workshops Series (WABWS, http://www.wabw.org) at the University of Ibadan, Nigeria (in collaboration with the South African National Bioinformatics Institute (SANBI, http:/www.sanbi.ac.za). Workshops that were open to scientists from all African countries have seen a very high number of applications from scientists based in West Africa. The encouraging desire to acquire cuttingedge skills to computational process data and extract useful knowledge from genome projects led to the interest of the West African Biotechnology Workshops (WABW) to develop an agenda to address the bioinformatics skills gap among scientists in West Africa. An increased commitment from agencies like NEPAD would be required in the provision of infrastructure to establish and sustain regional and national networks.

University of Ilorin (UIL)Ilorin:
The University of Ilorin was established in 1976 by the Federal Government of Nigeria. Bioinformatics activities started at the University in February 2003 with the establishment of the West African Bioinformatics Research Initiative (WABRI). However, progress has been rather slow due to inadequate funding. We are mainly engaged in Bioinformatics training at the introductory level and proteomics studies on various species of malaria parasites. Recently, we became interested in comparative genome analysis of various species of Plasmodium and the comparison of chloroquine sensitive and chloroquine resistant strains of Plasmodium falciparum. Other activities and areas of interest can be seen on our website, http://www.wabri.org, although not all our proposed interests have been fully implemented due to our level of funding.

Training:
The University of Ilorin has introduced M.Sc. and Ph.D. programmes in Computer Science (with options in Bioinformatics). The programme is based in the Department of Computer Science and emphasis is on the development of algorithms to solve problems in bioinformatics. The Covenant University offers M.Sc. and Ph.D in Computer Science with option in Bioinformatics (Computational Biology). Furthermore, through affiliated departments, the CBBM is been design to award Diploma and Degree certificates in Biotechnology.

Web sites and links: http://www.covenantuniversity.com http://www.run.edu.ng http://www.uniben.edu http://www.wabri.org http://www.wabw.org http://www.unilorin.edu.ng http://www.wabri.org http://www.asopah.org

Calculate the significance of the difference between two trends

BioStar — Tue, 14 Mar 2023 05:41:53 -0500

To calculate the significance of the difference between two trends, you can use a statistical test such as a t-test or ANOVA (analysis of variance). Here are the general steps to follow:

Define your null hypothesis (H0) and alternative hypothesis (H1). For example, H0 might be that there is no significant difference between the two trends, while H1 might be that there is a significant difference.
Collect data on the two trends. Make sure that the data is independent, normally distributed, and has equal variances.
Calculate the means and standard deviations of each trend.
Calculate the test statistic using a t-test or ANOVA. The test statistic will depend on the specific test you choose, but it will generally compare the difference in means between the two trends to the variability within each trend.
Determine the p-value associated with the test statistic. The p-value represents the probability of obtaining a test statistic as extreme as the one you calculated, assuming that the null hypothesis is true.
Compare the p-value to your chosen significance level (usually 0.05 or 0.01). If the p-value is less than or equal to the significance level, reject the null hypothesis and conclude that there is a significant difference between the two trends. If the p-value is greater than the significance level, fail to reject the null hypothesis and conclude that there is not enough evidence to support a significant difference.

It's important to note that the specific details of each step will depend on the type of test you choose and the software you use to perform the analysis.

The most common methods for comparing means include:

Methods	R function	Description
T-test	t.test()	Compare two groups (parametric)
Wilcoxon test	wilcox.test()	Compare two groups (non-parametric)
ANOVA	aov() or anova()	Compare multiple groups (parametric)
Kruskal-Wallis	kruskal.test()	Compare multiple groups (non-parametric)

RA Bioinformatics at Sir Ganga Ram Hospital, New Delhi

Sun, 14 Mar 2021 10:40:18 -0500

Opportunities available at Institute of Medical Genetics & Genomics, Sir Ganga Ram Hospital, New Delhi.

1) Senior Research Fellow under ICMR Project: M.Sc. (Life Sciences) with 2 years of experience (preferable in the field of Bioinformatics) or MBBS Degree.

2) Research Associate under ICMR Project: . Ph.D.(Life Science/Biotechnology/Bioinformatics) or equivalent degree or having 3 years of research, teaching and design and development experience after M.Tech with at least one research paper in science Citation Indexed (SCI) Journal.
Work experience in the area of Human genomics/Next Generation Sequencing data analysis/Big data genomics would be preferred.
Application link:

https://sgrh.com/joblist

Post Code: 2023, 2024

Nigerian Bioinformatics and Genomics Network (NBGN)

Tue, 31 Aug 2021 08:29:40 -0500

This is to announce the second official conference of the Nigerian Bioinformatics and Genomics Network (NBGN). October 11-13,2021 at Landmark University, Omu-Aran, Kwara State and Zoom ( conference link to be announced soon

#NBGN21

www.nbgn21conference.com

Selecting between Python 2 and Python 3?

Rahul Agarwal — Wed, 10 Jul 2013 16:30:58 -0500

Which version is best for bioinformatician to work on?