Main research topics:
- Comparative and Population Genomics of Plant Symbionts
- Parasite Genome Evolution
- Experimental Evolution of Microbial Symbionts and Parasites
- Phylogenomics of Early Branching Fungi

More at http://corradilab.weebly.com/

Bioinformatics Textbook Track

Find more about Rosalind puzzle at http://rosalind.info/problems/list-view/?location=bioinformatics-textbook-track

I will provide solution of all the Rosalind problem with Perl for community.

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A: He was getting too Sassy.

What did the bioinformatician say when he found out his team stopped using version control?

A: Y’all better Git!

Why did the computational biologist stay home from work?

A: He had a code!

Why was the bioinformatician's paper was rejected?

A: Journal thought it seemed scripted.

How can you tell that a Bioinformatics is working?

A: You can hear him Grunting!

Why bioinformatician always silence?

A: Because bioinformatician calmly whisper, “SSH”

Why was the bioinformatician always so sleepy?

A: He/She wasn’t given any Java.

Why did the program/software hanged?

A: Because genome float.

Why was the class upset that its parent died?

A: Because it wouldn’t be getting the inheritance!

Why did bioinformatician always works on the command line?

A: Because they don't want to scare you with huge amount of data!

Why did the bioinformatician attend the gay pride parade?

A: They supported polymorphism.

Why did bioinformatician prefer awk, PerlOneliner?

A: Because even computer can't handle to load the data.

Why don’t bioinformatician get along with others?

A: They’re too MEAN.

Why computational biologist are cool?

A: Because they are scripted!!

Why they talk $ unzip; strip; touch; finger; grep; mount; fsck; more; yes; fsck; fsck; umount; clean; sleep;

A: Ah, Ohhh, dude, these are *NIX commands

Did they really hack genome?

A: Yes, I guess so.

 http://metapred2cs.ibers.aber.ac.uk/

Address of the bookmark: https://github.com/martinjvickers/MetaPred2CS

More at

https://www.isas.de/files/redaktion/jobs/2021/18.60.1_Postdoc_deNBI_06_21_AS.pdf

https://www.isas.de/en/news/062021-post-doctoral-position-scientist-mfd-in-bioinformatics

The main features are, it supports many standard file formats such as GFF, BED, GTF, FASTA, VCF, BAM and it can be integrated with other browsers or tools for analysis of genome.

The MicroScope platform is available at this URL:

https://www.genoscope.cns.fr/agc/microscope

Address of the bookmark: http://microscope.readthedocs.org/en/latest/index.html

It was first developed to transfer annotations between different genome assembly versions. However, it can also transfer annotations between strains and even different species, like Plasmodium chabaudi onto P. berghei, between different Leishmania species or Salmonella enterica onto other Salmonella serotypes. RATT is able to transfer any entries present on a reference sequence, such as the systematic id or an annotator's notes; such information would be lost in a de novo annotation.

More at http://ratt.sourceforge.net/

Address of the bookmark: http://ratt.sourceforge.net/

• Automatically improve draft assemblies
• Find variation among strains, including large event detection

Pilon requires as input a FASTA file of the genome along with one or more BAM files of reads aligned to the input FASTA file. Pilon uses read alignment analysis to identify inconsistencies between the input genome and the evidence in the reads. It then attempts to make improvements to the input genome, including:

• Single base differences
• Small indels
• Larger indel or block substitution events
• Gap filling
• Identification of local misassemblies, including optional opening of new gaps

More at https://github.com/broadinstitute/pilon/wiki

Address of the bookmark: https://github.com/broadinstitute/pilon/wiki

Lift over is the process of transferring annotations from one genome assembly to another. Usually lift over is done because there is a new, improved genome assembly for the species and good quality annotations (maybe manually curated or experimentally verified) are available on the old assembly.

The idea is simple: align the new assembly with the old one (e.g., with BLAT), process the alignment data to define how a coordinate or coordinate range on the old assembly should be transformed to the new assembly (e.g., as a chain file), transform the coordinates (e.g., with liftOver).

https://github.com/wurmlab/flo

Address of the bookmark: https://github.com/wurmlab/flo