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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/32376?offset=1310</link>
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	<description><![CDATA[]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39913/twinblast-when-two-is-better-than-one</guid>
	<pubDate>Sat, 07 Sep 2019 08:50:08 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39913/twinblast-when-two-is-better-than-one</link>
	<title><![CDATA[TwinBLAST: When Two Is Better than One]]></title>
	<description><![CDATA[<p>TwinBLAST is a web-based tool for viewing 2 BLAST reports simultaneouslyside-by-side. It uses ExtJS (www.sencha.com/products/extjs/) to provide 2independently scrollable panels. BioPerl (www.bioperl.org) is used to indexraw BLAST reports and Bio::Graphics is used to draw pictograms of the BLASThits.</p>
<p><a href="https://github.com/IGS/twinblast">https://github.com/IGS/twinblast</a></p>
<p><a href="https://mra.asm.org/content/8/35/e00842-19">https://mra.asm.org/content/8/35/e00842-19</a></p><p>Address of the bookmark: <a href="https://github.com/IGS/twinblast" rel="nofollow">https://github.com/IGS/twinblast</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/10881/special-project-scientist-%E2%80%93-sorghum-genomics</guid>
  <pubDate>Tue, 20 May 2014 00:34:39 -0500</pubDate>
  <link></link>
  <title><![CDATA[Special Project Scientist – Sorghum Genomics]]></title>
  <description><![CDATA[
<p>ICRISAT is seeking applications from Indian Nationals for a Special Project Scientist to work on a sorghum genomics activities related to sequencing/re-sequencing projects utilizing New Generation Sequencing platforms.</p>

<p>The Job detail</p>

<p>    Advancing the SNP-discovery and polymorphism assessment work across several germplasm panels representing global genetic diversity<br />    Population genetic and genomic analyses, testing the hypothesis related to adaptation in multiple geographic regions<br />    Develop SNP assays from large scale GBS and other re-sequencing data for several target traits utilizing available phenotyping data<br />    Combined analyses of genotypic and phenotypic data for discovery of marker-trait associations, and conducting GWAS<br />    Processing, analyzing, and archiving large-scale genomic data sets, assessing data quality, conducting analyses, interpreting findings, and communicating findings to others including preparation of reports, presentations, posters and journal articles<br />    Providing support to MSc and PhD students on topic related to its major core of research<br />    Any other work assigned by the supervisor</p>

<p>The Person:</p>

<p>    PhD in bioinformatics, genetics, computational biology preferably with 1 to 2 years of experience;<br />    familiar with standard bioinformatics tools and scripting languages and emerging and evolving software platforms relevant to bioinformatics and computational biology;<br />    ability to create new analytical pipelines; experience with handling large data sets;<br />    ability to program in at least two of the following: C++, PERL, Python, R, Java.<br />    will use next-generation sequencing technologies to generate marker data for genetic mapping and transcriptome data for expression QTL mapping, and will be responsible for data generation as well as data analysis.</p>

<p>Period and Remuneration: The assignment is for a period of two years, and can be extended for another year depending on performance. ICRISAT pays a very attractive all inclusive lump sum assignment fee payable in Indian Rupees.</p>

<p>How to Apply: Please send your application by email to icrisatjobs@cgiar.org, stating the job title (Special project Scientist-Sorghum Genomics) clearly in the subject column, addressed to the Director, Human Resources and Operations, ICRISAT, Patancheru, Andhra Pradesh 502 324, India, latest by 10 June 2014. The application should include an up-to-date Curriculum Vitae, a short statement of competencies and experience for the position, and the names and addresses (including phone/e-mail) of three referees. Only short-listed candidates will be contacted.</p>

<p>More at: http://www.icrisat.org/careers/Special-Project-Scientist-Sorghum-Genomics.htm</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/10739/science-for-life-laboratory-scilifelab-sweden</guid>
  <pubDate>Sat, 10 May 2014 06:22:30 -0500</pubDate>
  <link></link>
  <title><![CDATA[Science for Life Laboratory (SciLifeLab)-Sweden]]></title>
  <description><![CDATA[
<p>Science for Life Laboratory (SciLifeLab) is a national center for molecular biosciences with focus on health and environmental research. The center combines frontline technical expertise with advanced knowledge of translational medicine and molecular bioscience. SciLifeLab is a national resource and a collaboration between four universities: Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University.</p>

<p>Webpage : https://www.scilifelab.se/about-us/<br />Opportunity: https://www.scilifelab.se/about-us/career/</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44711/blast-5-key-updates-and-enhancements-for-modern-bioinformatics</guid>
	<pubDate>Sat, 07 Dec 2024 22:37:48 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44711/blast-5-key-updates-and-enhancements-for-modern-bioinformatics</link>
	<title><![CDATA[BLAST+ 5: Key Updates and Enhancements for Modern Bioinformatics]]></title>
	<description><![CDATA[<p>The BLAST+ 5 (Basic Local Alignment Search Tool) update has introduced several key enhancements aimed at improving performance, user experience, and compatibility with evolving genomic data standards. Here are the major updates:</p><ol>
<li>
<p><strong>Database Enhancements</strong>:</p>
<ul>
<li>The BLAST databases have shifted fully to the version 5 (v5) format, which integrates built-in taxonomy information. This allows for more detailed and efficient sequence annotation and analysis.</li>
<li>Protein databases in v5 are now accession-based, supporting a broader range of sequences, including those from high-throughput projects and the Pathogen Detection Project. These databases also accommodate structural proteins with multi-character chain identifiers.</li>
</ul>
</li>
<li>
<p><strong>Performance Improvements</strong>:</p>
<ul>
<li>Adaptive Composition-Based Statistics (CBS) is available as an experimental feature, enhancing the detection of novel results in protein-protein comparisons.</li>
<li>Updated algorithms improve the stability of search results, especially when fewer hits are requested than the default output.</li>
</ul>
</li>
<li>
<p><strong>Compatibility</strong>:</p>
<ul>
<li>Support for the older v4 databases has been discontinued. The v5 format is now the default for all BLAST database updates, ensuring alignment with current standards in bioinformatics.</li>
</ul>
</li>
<li>
<p><strong>User-Friendly Changes</strong>:</p>
<ul>
<li>Naming conventions for databases have been simplified to enhance clarity and ease of use. For example, database names no longer include version tags like "_v5".</li>
</ul>
</li>
<li>
<p><strong>Future-Proofing</strong>:</p>
<ul>
<li>BLAST+ 5 aligns with current and upcoming data requirements, ensuring that researchers have access to the most comprehensive and modern resources for sequence alignment.</li>
</ul>
</li>
</ol><p>These updates reflect NCBI's commitment to maintaining BLAST as a leading tool for sequence analysis. For detailed release notes and additional guidance, refer to NCBI Insights <a href="https://ncbiinsights.ncbi.nlm.nih.gov/">here</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/10841/ra-at-iisr-kozhikode</guid>
  <pubDate>Thu, 15 May 2014 10:08:09 -0500</pubDate>
  <link></link>
  <title><![CDATA[RA at IISR Kozhikode]]></title>
  <description><![CDATA[
<p>INDIAN INSTITUTE OF SPICES RESEARCH<br />(Indian Council of Agricultural Research)<br />Marikunnu P.O., Kozhikode – 673 012, Kerala</p>

<p>Walk- in- Test cum Interview (based on test) for the selection of Research Associate</p>

<p>under the scheme “Distributed Information Sub Centre –DISC” &amp; Research Assistant under scheme “Phytophthora, Fusarium and Ralstonia diseases of Horticultural and Field Crops” will be held at this Institute as per details indicated below.</p>

<p>WALK -IN- TEST CUM INTERVIEW</p>

<p>Name of the post : Research Associate</p>

<p>Date of Interview : 21-05-2014 at 10.00 AM</p>

<p>No. of posts : One</p>

<p>Qualifications : a)Essential</p>

<p>Ph.D Degree in Bioinformatics OR :  Masters degree in Bioinformatics with a minimum of<br />60% marks or equivalent OGPA with at least two years research experience as evidenced from fellowship/ associateship/training/published papers etc.</p>

<p>b)Desirable: Experience in NGS data analysis.</p>

<p>Emoluments : Rs. 23,000/- per month + HRA (Masters Degree Holders)</p>

<p>Rs. 24,000/- per month + HRA (Ph.D Degree Holders)</p>

<p>Upper age limit : 40 years for Men &amp; 45 years for Women as on date of Interview (Upper Age limits are relaxable for SC, ST and OBC candidates as per Govt. of India norms (at present 5 years for SC/ST and 3 years for OBC)</p>

<p>Duration of Project : Till 31-03-2017.</p>

<p>Title of Assigment : Research Assistant (on contract basis)</p>

<p>No. of vacancy : One</p>

<p>Qualification : Essential : Post Graduation in Bioinformatics and  Minimum one year experience in NGS data analysis</p>

<p>Desirable : Experience in Perl/Python/R</p>

<p>Remuneration : Rs. 20,000/- per month (consolidated)</p>

<p>Scope of work :</p>

<p>1. Analysis of different file formats and their conversions.</p>

<p>2. Assessing the quality of data and filtering of raw reads.<br />3. Assembling the raw reads-de novo as well as reference  mapping.<br />4. Compression of aligned reads using Jam tools<br />5. RNA-seq. Analysis<br />6. Differential expression testing involving Normalization,  Statistical testing, heat map generation &amp; hierarchical  clustering<br />7. Annotating the assembled genome and geneet testing  and their validation<br />8. Metabolic pathway analysis<br />9. Comparative genomics<br />10. Setting up of genome browsers.</p>

<p>Period of Assigment : Initially for six months.</p>

<p>Date &amp; Venue of Interview : 21-05-2014 at IISR, Kozhikode at 10.00 AM</p>

<p>More at http://www.spices.res.in/pdf/disc-advtmnt.pdf</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/view/1926</guid>
	<pubDate>Sun, 11 Aug 2013 11:42:32 -0500</pubDate>
	<link>https://bioinformaticsonline.com/view/1926</link>
	<title><![CDATA[Want to Know which genome assembler rule the world ?]]></title>
	<description><![CDATA[<p><span><strong>Assemblathon 2</strong>: evaluating de novo methods of genome assembly&nbsp;</span></p><p><span><a href="http://www.gigasciencejournal.com/content/2/1/10/abstract">http://www.gigasciencejournal.com/content/2/1/10/abstract</a></span></p><p><span><a href="http://blogs.nature.com/news/2013/07/genome-assembly-contest-prompts-soul-searching.html">http://blogs.nature.com/news/2013/07/genome-assembly-contest-prompts-soul-searching.html</a></span></p><p><a href="http://assemblathon.org/post/44431915644/feedback-and-analysis-of-the-assemblathon-2-p">http://assemblathon.org/post/44431915644/feedback-and-analysis-of-the-assemblathon-2-p</a></p><p>&nbsp;</p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
</item>

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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/11000/professorassociate-professor-assistant-professor-at-chettinad-academy-of-research-and-education</guid>
  <pubDate>Sat, 24 May 2014 00:00:15 -0500</pubDate>
  <link></link>
  <title><![CDATA[Professor/Associate Professor/ Assistant Professor at Chettinad Academy of Research and Education]]></title>
  <description><![CDATA[
<p>OPEN FACULTY POSITION</p>

<p>Chettinad Academy of Research and Education (CARE) invites applications from eligible and translational research-oriented candidates to the posts of Professor/Associate Professor/ Assistant Professor  Computational Biology, Bioinformatics, and Pharmaceutical Chemistry.</p>

<p>Emoluments: As per UGC norms (Adequate Compensation for Postdoctoral/Teaching experience)</p>

<p>Candidates fulfilling the eligibility criteria as per the UGC norms can send their full CV with copies of certificates and reference letters to the following address by post or by e-mail on or before 31st May 2014</p>

<p>The Registrar,<br />Chettinad Academy of Research and Education,<br />Chettinad Health City<br />Kelambakkam, Chennai 603 103<br />Tamil Nadu<br />T +91 (0)44 4741 1000<br />F +91 (0)44 4741 1011<br />Email: jobs @chettinadhealthcity.com</p>

<p>Advertisement: http://182.73.176.163/chc/ads2014.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/3918/the-human-genome-project-video-3d-animation-introduction-low</guid>
	<pubDate>Sat, 24 Aug 2013 19:01:19 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/3918/the-human-genome-project-video-3d-animation-introduction-low</link>
	<title><![CDATA[The Human Genome Project Video   3D Animation Introduction Low)]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/YxoQFSBwyms" frameborder="0" allowfullscreen></iframe>]]></description>
	
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/11107/the-minerva-research-group-for-bioinformatics</guid>
  <pubDate>Tue, 27 May 2014 15:48:14 -0500</pubDate>
  <link></link>
  <title><![CDATA[The Minerva Research Group for Bioinformatics]]></title>
  <description><![CDATA[
<p>The focus of the bioinformatics group is to use computational approaches to gain an insight into genome evolution in primates.</p>

<p>http://www.eva.mpg.de/genetics/bioinformatics/overview.html?Fsize=0%2C%20%40%2F%27</p>

<p>Kelso Group<br />Department of Evolutionary Genetics<br />Max Planck Institute for Evolutionary Anthropology<br />Deutscher Platz 6<br />04103 Leipzig<br />Germany<br />Phone: +49 341 3550 500</p>

<p>Job: <br />http://www.eva.mpg.de/genetics/bioinformatics/jobs.html?Fsize=0%2C%2B%40</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4762/how-dna-is-packaged-advanced</guid>
	<pubDate>Mon, 23 Sep 2013 18:08:34 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4762/how-dna-is-packaged-advanced</link>
	<title><![CDATA[How DNA is Packaged (Advanced)]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/gbSIBhFwQ4s" frameborder="0" allowfullscreen></iframe>Each chromosome consists of one continuous thread-like molecule of DNA coiled tightly around proteins, and contains a portion of the 6,400,000,000 basepairs (DNA building blocks) that make up your DNA. 
Originally created for DNA Interactive ( http://www.dnai.org ).
TRANSCRIPT: In this animation we'll see the remarkable way our DNA is tightly packed up to fit into the nucleus of every cell. The process starts with assembly of a nucleosome, which is formed when eight separate histone protein subunits attach to the DNA molecule. The combined tight loop of DNA and protein is the nucleosome. Six nucleosomes are coiled together and these then stack on top of each other. The end result is a fiber of packed nucleosomes known as chromatin. This structure, is then looped and further packaged using other proteins (which are not shown here) to give the final "chromosomal" shapes. It is this remarkable multiple folding which allows six feet of DNA to fit into the nucleus of each cell in our body. And a typical cell nucleus is so small that ten thousand could fit on the tip of a needle. It is important to realize that chromosomes are not always present, they form only when cells are dividing. At other times, as we can see here at the end of cell division, our DNA becomes less highly organized.)]]></description>
	
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