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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/32465?offset=1060</link>
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	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44620/diy-transcriptomics</guid>
	<pubDate>Wed, 31 Jul 2024 01:19:26 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44620/diy-transcriptomics</link>
	<title><![CDATA[DIY Transcriptomics]]></title>
	<description><![CDATA[<p><span>A semester-long course covering best practices for the analysis of high-throughput sequencing data from gene expression (RNA-seq) studies, with a primary focus on empowering students to be independent in the use of lightweight and open-source software using the R programming language and the Bioconductor suite of packages. This course follows a hybrid format in which online lectures are paired with in-person labs where students participate in hands-on, live coding exercises using real &lsquo;omic datasets. The course is focused on datasets and topics central to infectious disease research, immunology, and One-Health, but the concepts and approaches covered are applicable to any genomic study.</span></p>
<p>https://diytranscriptomics.com</p><p>Address of the bookmark: <a href="https://diytranscriptomics.com" rel="nofollow">https://diytranscriptomics.com</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44900/pegas-a-comprehensive-bioinformatic-solution-for-pathogenic-bacterial-genomic-analysis</guid>
	<pubDate>Mon, 01 Sep 2025 01:18:10 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44900/pegas-a-comprehensive-bioinformatic-solution-for-pathogenic-bacterial-genomic-analysis</link>
	<title><![CDATA[PeGAS: A Comprehensive Bioinformatic Solution for Pathogenic Bacterial Genomic Analysis]]></title>
	<description><![CDATA[<p><span>This is PeGAS, a powerful bioinformatic tool designed for the seamless quality control, assembly, and annotation of Illumina paired-end reads specific to pathogenic bacteria. This tool integrates state-of-the-art open-source software to provide a streamlined and efficient workflow, ensuring accurate insights into the genomic makeup of pathogenic microbial strains.</span></p>
<p><span><img src="https://github.com/liviurotiul/PeGAS/raw/main/Features.png" alt="image" style="border: 0px;"></span></p><p>Address of the bookmark: <a href="https://github.com/liviurotiul/PeGAS" rel="nofollow">https://github.com/liviurotiul/PeGAS</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/42165/bioinformatics-scientistresearch-software-engineer-at-university-of-dundee-dundee-united-kingdom</guid>
  <pubDate>Wed, 26 Aug 2020 10:31:25 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatics Scientist/Research Software Engineer at University of Dundee Dundee, United Kingdom]]></title>
  <description><![CDATA[
<p>We are recruiting for an exceptional individual to join us as a computational scientist, bioinformatician, or (research) software engineer with an interest in interactive data analysis platforms for biology and medicine within our Jalview (www.jalview.org) research software engineering team.</p>

<p>More at https://www.jobs.dundee.ac.uk/fe/tpl_uod01.asp?s=4A515F4E5A565B1A&amp;jobid=104342,2382988671&amp;key=147934117&amp;c=99413415238921&amp;pagestamp=sesxbbuyifokdsfygf</p>

<p>Last date: 30th August 2020</p>

<p>Informal enquiries about this position may be made to Prof. Geoff Barton (gjbarton@dundee.ac.uk) or Dr Jim Procter (jprocter@dundee.ac.uk). To find out more about Jalview research software engineering team please visit www.jalview.org and www.compbio.dundee.ac.uk</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/34463/single-cell-rnaseq-data-analysis-tutorial</guid>
	<pubDate>Mon, 27 Nov 2017 16:24:29 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/34463/single-cell-rnaseq-data-analysis-tutorial</link>
	<title><![CDATA[Single Cell RNAseq data analysis tutorial !!]]></title>
	<description><![CDATA[<ul>
<li>A major breakthrough (replaced microarrays) in the late 00&rsquo;s and has been widely used since</li>
<li>Measures the&nbsp;average expression level&nbsp;for each gene across a large population of input cells</li>
<li>Useful for comparative transcriptomics, e.g.&nbsp;samples of the same tissue from different species</li>
<li>Useful for quantifying expression signatures from ensembles, e.g.&nbsp;in disease studies</li>
<li>Insufficient&nbsp;for studying heterogeneous systems, e.g.&nbsp;early development studies, complex tissues (brain)</li>
<li>Does&nbsp;not&nbsp;provide insights into the stochastic nature of gene expression</li>
</ul><p>Following are the useful links:</p><p><a href="http://hemberg-lab.github.io/scRNA.seq.course/scRNA-seq-course.pdf" target="_blank">Single Cell RNAseq data analysis Tutorial</a></p><p><a href="https://f1000research.com/articles/5-2122/v2" target="_blank">A step-by-step workflow for low-level analysis of single-cell RNA-seq data</a></p><p><a href="https://www.bioconductor.org/help/workflows/simpleSingleCell/" target="_blank">A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor</a></p><p>SCell: single-cell RNA-seq analysis software</p><p><a href="https://github.com/diazlab/SCell">https://github.com/diazlab/SCell</a></p><p>Beta-Poisson model for single-cell RNA-seq data analyses</p><p><a href="https://github.com/nghiavtr/BPSC">https://github.com/nghiavtr/BPSC</a></p><p>Sincera: A Computational Pipeline for Single Cell RNA-Seq Profiling Analysis</p><p><a href="https://research.cchmc.org/pbge/sincera.html">https://research.cchmc.org/pbge/sincera.html</a></p><p>SC3 &ndash; consensus clustering of single-cell RNA-Seq data</p><p><a href="http://biorxiv.org/content/early/2016/09/02/036558">http://biorxiv.org/content/early/2016/09/02/036558</a></p><p>Citrus: A toolkit for single cell sequencing analysis</p><p><a href="http://biorxiv.org/content/early/2016/09/14/045070">http://biorxiv.org/content/early/2016/09/14/045070</a></p><p>Single-Cell Resolution of Temporal Gene Expression during Heart Development</p><p><a href="http://www.cell.com/developmental-cell/fulltext/S1534-5807%2816%2930682-7">http://www.cell.com/developmental-cell/fulltext/S1534-5807(16)30682-7</a></p><p>Scalable latent-factor models applied to single-cell RNA-seq data separate biological drivers from confounding effects</p><p><a href="http://biorxiv.org/content/early/2016/11/15/087775">http://biorxiv.org/content/early/2016/11/15/087775</a></p><p>Single cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes</p><p><a href="http://genome.cshlp.org/content/early/2016/11/18/gr.212720.116.abstract">http://genome.cshlp.org/content/early/2016/11/18/gr.212720.116.abstract</a></p><p>SCODE: An efficient regulatory network inference algorithm from single-cell RNA-Seq during differentiation</p><p><a href="http://biorxiv.org/content/early/2016/11/21/088856">http://biorxiv.org/content/early/2016/11/21/088856</a></p><p>SCOUP is a probabilistic model to analyze single-cell expression data during differentiation</p><p><a href="https://github.com/hmatsu1226/SCOUP">https://github.com/hmatsu1226/SCOUP</a></p><p>scLVM is a modelling framework for single-cell RNA-seq data</p><p><a href="https://github.com/PMBio/scLVM">https://github.com/PMBio/scLVM</a></p><p>Selective Locally linear Inference of Cellular Expression Relationships (SLICER) algorithm for inferring cell trajectories</p><p><a href="https://github.com/jw156605/SLICER">https://github.com/jw156605/SLICER</a></p><p>SinQC: A Method and Tool to Control Single-cell RNA-seq Data Quality</p><p><a href="http://www.morgridge.net/SinQC.html">http://www.morgridge.net/SinQC.html</a></p><p>TSCAN: Pseudo-time reconstruction and evaluation in single-cell RNA-seq analysis</p><p><a href="https://github.com/zji90/TSCAN">https://github.com/zji90/TSCAN</a></p><p>Visualization and cellular hierarchy inference of single-cell data using SPADE</p><p><a href="http://www.nature.com/nprot/journal/v11/n7/full/nprot.2016.066.html">http://www.nature.com/nprot/journal/v11/n7/full/nprot.2016.066.html</a></p><p>OEFinder: Identify ordering effect genes in single cell RNA-seq data</p><p><a href="https://github.com/lengning/OEFinder">https://github.com/lengning/OEFinder</a></p>]]></description>
	<dc:creator>Robert M Willioms</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/42227/two-faculty-positions-at-national-taiwan-university-taipei-taiwan</guid>
  <pubDate>Thu, 22 Oct 2020 04:53:12 -0500</pubDate>
  <link></link>
  <title><![CDATA[Two Faculty Positions at National Taiwan University, Taipei, Taiwan]]></title>
  <description><![CDATA[
<p>The Department of Agronomy at National Taiwan University, Taipei, Taiwan,<br />invites applications for two full-time faculty positions beginning August<br />1, 2021 at the rank of Assistant Professor, Associate Professor or<br />Professor in Biometry and Bioinformatics and Plant Breeding and Genetics,<br />respectively.</p>

<p>A qualified candidate should hold a Ph.D. in a relevant field including<br />Agronomy, Statistics, Bioinformatics, Plant Breeding, Plant Genetics or<br />Quantitative Genetics. For the position in Biometry and Bioinformatics, the<br />applicants capable of teaching fundamental statistics/bioinformatics<br />courses or with experience in crop science are preferable; for Plant<br />Breeding and Genetics, the applicants capable of teaching fundamental plant<br />breeding courses, with experience in crop breeding, or training in<br />quantitative genetics are preferred.</p>

<p>The application package should include two letters of reference and five<br />printed copies of the following documents (1) curriculum vitae, (2)<br />publication list, (3) undergraduate and graduate transcripts if applying<br />for the Assistant Professorship, (4) a photocopy of the Ph.D. diploma, (5)<br />teaching plan and course outline or syllabus (6) research proposal, (7) a<br />cover letter indicating the rank to apply, and one representative original<br />research article which was published by the applicant being the 1st or<br />corresponding author in an SCI peer-reviewed journal within 5 years (after<br />August 1, 2016); a copy of doctoral dissertation can be the representative<br />article if applying for the Assistant Professorship; (8) reprints of the<br />selected publications published within 7 years (after August 1, 2014).</p>

<p>The application package should mail to the Chair, Dr. Li-yu Daisy Liu<br />(lyliu@ntu.edu.tw), in the Department of Agronomy, National Taiwan<br />University, No. 1, Section 4, Roosevelt Road, Taipei 10617, Taiwan, before<br />December 15, 2020 for full consideration.</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34715/delta-a-new-web-based-3d-genome-visualization-and-analysis-platform</guid>
	<pubDate>Wed, 20 Dec 2017 08:49:55 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34715/delta-a-new-web-based-3d-genome-visualization-and-analysis-platform</link>
	<title><![CDATA[Delta: a new Web-based 3D genome visualization and analysis platform]]></title>
	<description><![CDATA[<p><em>Delta</em><span>&nbsp;is an integrative visualization and analysis platform to facilitate visually annotating and exploring the 3D physical architecture of genomes.&nbsp;</span><em>Delta</em><span>&nbsp;takes Hi-C or ChIA-PET contact matrix as input and predicts the topologically associating domains and chromatin loops in the genome. It then generates a physical 3D model which represents the plausible consensus 3D structure of the genome.&nbsp;</span><em>Delta</em><span>features a highly interactive visualization tool which enhances the integration of genome topology/physical structure with extensive genome annotation by juxtaposing the 3D model with diverse genomic assay outputs.</span></p>
<p>https://github.com/zhangzhwlab/delta</p><p>Address of the bookmark: <a href="https://github.com/zhangzhwlab/delta" rel="nofollow">https://github.com/zhangzhwlab/delta</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/42326/edanchin-lab</guid>
  <pubDate>Thu, 19 Nov 2020 08:00:07 -0600</pubDate>
  <link></link>
  <title><![CDATA[Edanchin Lab]]></title>
  <description><![CDATA[
<p>My main topics of interest are:</p>

<p>The impact of non tree-like evolution such as horizontal gene transfers and hybridization on species biology<br />Evolution and adaptation of animals in the absence of sexual reproduction and the underlying mechanisms<br />Genomic signatures of adaptation to a parasitic life-style</p>

<p>More at https://edanchin.org/</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/35384/mgcv-the-microbial-genomic-context-viewer-for-comparative-genome-analysis</guid>
	<pubDate>Mon, 29 Jan 2018 04:55:46 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/35384/mgcv-the-microbial-genomic-context-viewer-for-comparative-genome-analysis</link>
	<title><![CDATA[MGcV: the microbial genomic context viewer for comparative genome analysis]]></title>
	<description><![CDATA[<p><span>MGcV is an interactive web-based visalization tool tailored to facilitate small scale genome analysis. To start using MGcV:</span></p>
<ol>
<li>Supply your genes/genomic segments/phylogenetic tree of interest in the input-box by
<ul>
<li>selecting the type of identifier and pasting identifiers (one per line)</li>
<li><em><strong>or</strong></em>&nbsp;by using the&nbsp;<a>gene ID search tool</a></li>
<li><em><strong>or</strong></em>&nbsp;with the&nbsp;<a>BLAST search tool</a></li>
</ul>
</li>
<li>Click "Visualize context".</li>
</ol>
<p><span>Consult the&nbsp;</span><a href="http://mgcv.cmbi.ru.nl/help.html" target="_blank">documentation</a><span>&nbsp;to learn more about MGcV.</span></p><p>Address of the bookmark: <a href="http://mgcv.cmbi.ru.nl/" rel="nofollow">http://mgcv.cmbi.ru.nl/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42672/introduction-to-bioinformatics-and-computational-biology</guid>
	<pubDate>Mon, 25 Jan 2021 01:32:30 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42672/introduction-to-bioinformatics-and-computational-biology</link>
	<title><![CDATA[Introduction to Bioinformatics and Computational Biology]]></title>
	<description><![CDATA[<p><span>This is the course material for STAT115/215 BIO/BST282 at Harvard University.</span></p>
<p>Xiaole Shirley Liu (lead instructor)<br>Joshua Starmer<br>Martin Hemberg<br>Ting Wang<br>Feng Yue</p>
<p>Ming Tang<br>Yang Liu<br>Jack Kang<br>Scarlett Ge<br>Jiazhen Rong<br>Phillip Nicol<br>Maartin De Vries</p>
<p>We thank many colleagues in the community, who helped Dr.&nbsp;Liu in prepare the STAT115/215 BIO/BST282 course over the years.&nbsp;</p><p>Address of the bookmark: <a href="https://liulab-dfci.github.io/bioinfo-combio/" rel="nofollow">https://liulab-dfci.github.io/bioinfo-combio/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37239/kat-a-k-mer-analysis-toolkit-to-quality-control-ngs-datasets-and-genome-assemblies</guid>
	<pubDate>Fri, 06 Jul 2018 03:36:45 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37239/kat-a-k-mer-analysis-toolkit-to-quality-control-ngs-datasets-and-genome-assemblies</link>
	<title><![CDATA[KAT: a K-mer analysis toolkit to quality control NGS datasets and genome assemblies]]></title>
	<description><![CDATA[<p>KAT is a suite of tools that analyse jellyfish hashes or sequence files (fasta or fastq) using kmer counts. The following tools are currently available in KAT:</p>
<ul>
<li><span>hist</span>: Create an histogram of k-mer occurrences from a sequence file. Adds metadata in output for easy plotting.</li>
<li><span>gcp:</span>&nbsp;K-mer GC Processor. Creates a matrix of the number of K-mers found given a GC count and a K-mer count.</li>
<li><span>comp</span>: K-mer comparison tool. Creates a matrix of shared K-mers between two (or three) sequence files or hashes.</li>
<li><span>sect</span>: SEquence Coverage estimator Tool. Estimates the coverage of each sequence in a file using K-mers from another sequence file.</li>
<li><span>blob</span>: Given, reads and an assembly, calculates both the read and assembly K-mer coverage along with GC% for each sequence in the assembly.SEquence Coverage estimator Tool.</li>
<li><span>filter</span>: Filtering tools. Contains tools for filtering k-mer hashes and FastQ/A files:
<ul>
<li><span>kmer</span>: Produces a k-mer hash containing only k-mers within specified coverage and GC tolerances.</li>
<li><span>seq</span>: Filters a sequence file based on whether or not the sequences contain k-mers within a provided hash.</li>
</ul>
</li>
<li><span>plot</span>: Plotting tools. Contains several plotting tools to visualise K-mer and compare distributions. The following plot tools are available:
<ul>
<li><span>density</span>: Creates a density plot from a matrix created with the "comp" tool. Typically this is used to compare two K-mer hashes produced by different NGS reads.</li>
<li><span>profile</span>: Creates a K-mer coverage plot for a single sequence. Takes in fasta coverage output coverage from the "sect" tool</li>
<li><span>spectra-cn</span>: Creates a stacked histogram using a matrix created with the "comp" tool. Typically this is used to compare a jellyfish hash produced from a read set to a jellyfish hash produced from an assembly. The plot shows the amount of distinct K-mers absent, as well as the copy number variation present within the assembly.</li>
<li><span>spectra-hist</span>: Creates a K-mer spectra plot for a set of K-mer histograms produced either by jellyfish-histo or kat-histo.</li>
<li><span>spectra-mx</span>: Creates a K-mer spectra plot for a set of K-mer histograms that are derived from selected rows or columns in a matrix produced by the "comp".</li>
</ul>
</li>
</ul>
<p>In addition, KAT contains a python script for analysing the mathematical distributions present in the K-mer spectra in order to determine how much content is present in each peak.</p>
<p>This README only contains some brief details of how to install and use KAT. For more extensive documentation please visit:&nbsp;<a href="https://kat.readthedocs.org/en/latest/">https://kat.readthedocs.org/en/latest/</a></p>
<p><a href="https://academic.oup.com/bioinformatics/article/33/4/574/2664339">https://academic.oup.com/bioinformatics/article/33/4/574/2664339&nbsp;</a></p><p>Address of the bookmark: <a href="https://github.com/TGAC/KAT" rel="nofollow">https://github.com/TGAC/KAT</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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