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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/32709?offset=1120</link>
	<atom:link href="https://bioinformaticsonline.com/related/32709?offset=1120" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/30928/jrf-bioinformatics-job-vacancies-in-tezpur-university</guid>
  <pubDate>Tue, 14 Feb 2017 16:40:26 -0600</pubDate>
  <link></link>
  <title><![CDATA[JRF Bioinformatics job vacancies in Tezpur University]]></title>
  <description><![CDATA[
<p>Memo No. DoRD/CSE/SSS/20-295/112-A Date: 01/02/2017</p>

<p>Project Title : Integrating genome scale metabolic analysis of model plant pathogen Ralstonia solanacearum with RNAseq and fluxomics</p>

<p>Essential qualification : M.Tech. in CSE/IT (With specialization in Computational Biology/Bioinformatics) or M.Sc. in Bioinformatics/Biosciences/Molecular Biology Biotechnology preferably with NET/GATE/BET. Candidates should have minimum 55 % mark both in 10th and 10+2 Science examinations and mathematics at 10+2 Science. Desirable: Preference will be given to the candidates having experience in computational analysis of genome sequences or similar projects.</p>

<p>No. of Post : 01</p>

<p>Remuneration : Rs. 25,000/- for the 1st two years and Rs. 28,000/- for the 3rd year for SRF and applicable to the candidate having post graduate degree in Basic Science with NET/GATE/BET qualification or post graduate degree in professional course. Rs. 12,000/- for the 1st two years and Rs. 14,000/- for the 3 rd year for SRF, </p>

<p>Age : 28 years</p>

<p>Duration : Three (03) years or till completion of the project or until further order, whichever is earlier.</p>

<p>Hiring Process : Walk - In<br />Job Role: Research/JRF/SRF</p>

<p>Walk-in-interview will be held on 17th February, 2017, 11.15 a.m. at the office of the Head, Department of Computer Science and Engineering, Tezpur University.</p>

<p>Interested candidates may appear before the interview board with original documents from 10th standard onwards and photocopies of mark sheets, certificates, testimonials, caste certificate (if applicable), experience certificate certificates of NET/GATE/BET or similar examination qualifications, any other testimonials and a copy of recent curriculum vitae (CV) on the day of interview.</p>

<p>More at http://www.tezu.ernet.in/ProjectWalkin/Advt-DoRD-CSE-SSS-20-295-112-A.pdf</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/32227/postdoctoral-research-position-in-bioinformatics-in-milan</guid>
  <pubDate>Thu, 20 Apr 2017 12:53:12 -0500</pubDate>
  <link></link>
  <title><![CDATA[Postdoctoral Research Position in Bioinformatics in Milan]]></title>
  <description><![CDATA[
<p>The lab of Immunobiology of Neurological Disorders has a main interest in the biological processes associated with multiple sclerosis, an inflammatory disorder of the central nervous system. The projects of interest for this application involve research on translational bioinformatics in complex human neurological disorders.</p>

<p>You have a  PhD in Computational Science, Bioinformatics,  or equivalent, and expertise in analysis and modeling of human RNA-seq data, statistics, data mining and machine learning. Excellent communication skills in English (written and oral) is a must. Flexibility and willingness to work across multiple projects and technologies in a rapidly evolving scientific context is required.<br />Salary will depend on qualification and experience. Starting date: immediate.</p>

<p>Interested candidates should send to farina.cinthia@hsr.it:</p>

<p>1. CV (please show evidences of relevant titles, projects, courses, references, etc.)           <br />2. One page with a list of research topics (i.e. ongoing projects)     <br />3. earliest availability</p>

<p>4. 2-3 contact names</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31976/snpgenie</guid>
	<pubDate>Thu, 30 Mar 2017 17:38:02 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31976/snpgenie</link>
	<title><![CDATA[SNPGenie]]></title>
	<description><![CDATA[<p>SNPGenie is a Perl script for estimating evolutionary parameters, mainly from pooled next-generation sequencing (NGS) single-nucleotide polymorphism (SNP) variant data. SNP reports (acceptable in a variety of formats) much each correspond to a single population, with variants called relative to a single reference sequence (one sequence in one FASTA file). Just run the main script, <strong>snpgenie.pl</strong>, in a directory containing the necessary <a href="https://github.com/hugheslab/snpgenie#snpgenie-input">input files</a>, and we take care of the rest! For the earlier version, see <a href="http://ww2.biol.sc.edu/~austin/">Hughes Lab Bioinformatics Resource</a>.</p><p>Address of the bookmark: <a href="https://github.com/hugheslab/snpgenie" rel="nofollow">https://github.com/hugheslab/snpgenie</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/32358/list-of-goi-approved-peer-reviewed-bioinformatics-and-computational-biology-journals</guid>
	<pubDate>Tue, 25 Apr 2017 05:03:27 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/32358/list-of-goi-approved-peer-reviewed-bioinformatics-and-computational-biology-journals</link>
	<title><![CDATA[List of GOI approved peer reviewed bioinformatics and computational biology journals]]></title>
	<description><![CDATA[<p>Unfortunately, we now live in a world where the integrity of peer-reviewed journals is being threatened by the rise of the academic version of fake news &ndash; something many call &ldquo;predatory publishing". &nbsp;Mostly in academic publishing world, "predatory open access publishing" is an exploitative open-access publishing business model that involves charging publication fees to authors without providing the editorial and publishing services associated with legitimate journals (open access or not).</p><p>Nearly 20% of the such journals have a flashy impact factor and quick publication time, which are quick give-aways. Interestingly, under contact address, some journal websites do not even provide any address to contact. All of this has led to the emergence of a new and dark market of deceptive publishers that exploit the concept of open access and provide channels for &ldquo;scientific journal&rdquo; publication with little or no peer review. For a fee, they will publish almost anything &ndash; even if the study was fatally flawed. And these journals provide a forum that can be used as a channel to publish fraudulent &ldquo;advocacy research.&rdquo; You can find list of certain such publishers at "Beall's List" http://beallslist.weebly.com/</p><p>Keeping all these in mind, Government of India (GOI) decided to approved certain bioinformatics and computational biology journals for your research publication.<br /> <br />Following are the list of GOI validated and peer reviewed bioinformatics and computational biology journals:</p><p><strong>NOTE:Each journal details are in following order Tittle\nSource\nSubject. </strong><br /><strong>Point to remember: The list of journals are NOT sorted in any ascending or descending order.</strong></p><p><em>If I missed any other GOI validated bioinformatics journal, then please report me in comment section.</em></p><p><strong>Open Bioinformatics Journal</strong> <br />Scopus <br />Computer Science; Engineering; Medicine</p><p><strong>PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS</strong> <br />WoS <br />BIOLOGY &amp; BIOCHEMISTRY</p><p><strong>Advances and Applications in Bioinformatics and Chemistry</strong><br />Scopus<br />Biochemistry, Genetics and Molecular Biology Chemistry; Computer Science</p><p><strong>Advances in Bioinformatics</strong><br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science; Engineering</p><p><strong>Applied Bioinformatics</strong><br />Scopus<br />Agricultural and Biological Sciences; Computer Science</p><p><strong>BIOINFORMATICS</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Bioinformatics and Biology Insights</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science; Mathematics</p><p><strong>BMC BIOINFORMATICS</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>BRIEFINGS IN BIOINFORMATICS</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Computational systems bioinformatics / Life Sciences Society. Computational Systems Bioinformatics Conference</strong> <br />Scopus <br />Medicine</p><p><strong>Current Bioinformatics</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Current Protocols in Bioinformatics</strong> <br />Scopus <br />Biochemistry, Genetics and Molecular Biology</p><p><strong>JOURNAL OF COMPUTATIONAL INTELLIGENCE IN BIOINFORMATICS</strong> <br />ICI <br />BIOLOGICAL SCIENCE</p><p><strong>Journal of integrative bioinformatics</strong> <br />Scopus <br />Medicine</p><p><strong>Journal of Proteomics and Bioinformatics</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science</p><p><strong>Mathematical Biology and Bioinformatics</strong> <br />Scopus <br />Engineering; Mathematics</p><p><strong>Trends in Bioinfprmatics</strong><br />Scopus <br />Computer Science</p><p><strong>Eurasip Journal on Bioinformatics and Systems Biology</strong> <br />Scopus<br />General; Computer Science; Mathematics; Medicine</p><p><strong>Evolutionary Bioinformatics</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>Genomics, Proteomics and Bioinformatics</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology;Mathematics</p><p><strong>IEEE/ACM Transactions on Computational Biology and Bioinformatics</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology;Mathematics</p><p><strong>IEEE-ACM Transactions on Computational Biology and Bioinformatics</strong> <br />WoS <br />COMPUTER SCIENCE</p><p><strong>International Journal of Bioinformatics Research and Application</strong><br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Medicine, Health</p><p><strong>International Journal o f Data M ining and Bioinformatics</strong> <br />WoS &amp; Scopus <br />COMPUTER SCIENCE</p><p><strong>IPSJ Transactions on Bioinformatics</strong> <br />Scopus <br />Biochemistry, Genetics and Molecular Biology;Computer Science</p><p><strong>Journal of Bioinformatics and Computational Biology</strong> <br />WoS &amp; Scopus<br />COMPUTER SCIENCE</p><p><strong>Journal of Clinical Bioinformatics</strong> <br />Scopus <br />Medicine</p><p><strong>PLoS Computational Biology</strong> <br />WoS &amp; Scopus <br />BIOLOGY &amp; BIOCHEMISTRY</p><p><strong>Reviews in Computational Chemistry</strong> <br />WoS &amp; Scopus <br />CHEMISTRY</p><p><strong>RSC Theoretical and Computational Chemistry Series</strong><br />Scopus <br />Chemistry; Computer Science</p><p><strong>Annual Reports in Computational Chemistry</strong> <br />Scopus <br />Chemistry; Mathematics</p><p><strong>Computational and Structural Biotechnology Journal</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology; Computer Science</p><p><strong>Computational and Theoretical Chemistry</strong> <br />WoS &amp; Scopus <br />CHEMISTRY</p><p><strong>COMPUTATIONAL BIOLOGY AND CHEMISTRY</strong> <br />WoS &amp; Scopus<br />COMPUTER SCIENCE</p><p><strong>COMPUTATIONAL CHEMISTRY</strong> <br />WoS <br />CHEMISTRY</p><p><strong>Journal of Theoretical and Computational Chemistry</strong> <br />Scopus<br />Chemistry; Computer Science</p><p><strong>Theoretical and Computational Chemistry</strong> <br />Scopus <br />Chemistry</p><p><strong>Wiley Interdisciplinary Reviews: Computational Molecular Science</strong> <br />Scopus<br />Biochemistry, Genetics and Molecular Biology;Chemistry; Computer Science; Materials Science; Mathematics</p><p><strong>Wiley Interdisciplinary Reviews- Computational Molecular Science</strong> <br />WoS <br />CHEMISTRY</p><p><strong>Interdisciplinary sciences, computational life sciences</strong><br />Scopus<br />Medicine</p><p><strong>Interdisciplinary Sciences-Computational Life Science</strong><br />WoS<br />Biology and Biochemistry</p><p><strong>International Journal of Computational Biology and Drug Design</strong><br />Scopus<br />Computer Science; Pharmacology, Toxicology and Pharmaceutics</p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/32496/bioinformatician-at-23andme</guid>
  <pubDate>Sat, 06 May 2017 17:57:39 -0500</pubDate>
  <link></link>
  <title><![CDATA[Bioinformatician at 23andMe]]></title>
  <description><![CDATA[
<p>23andMe’s mission is to help people access, understand, and benefit<br />from the human genome. We are a group of passionate individuals excited<br />to push the boundaries of what’s possible to help turn genetic insight<br />into better health and personal understanding.</p>

<p>Our Research Team prides itself on driving cutting edge, industrial-scale<br />science to make an impact that belies the team’s size, in an environment<br />and culture that fosters creativity, innovation, collaboration, and fun.</p>

<p>More than 80% of our customers consent to participate in research, and as<br />a result of their participation, we have one of the largest recontactable,<br />genotyped, and phenotyped research cohorts in the world. The scope and<br />breadth of our vision means that most of the methods and tools necessary<br />to unlock the potential of this unique resource for discovery have yet<br />to be developed.</p>

<p>Our science has garnered the respect of many members of the<br />broader scientific community. For a list of our publications, see<br />www.23andme.com/publications/for-scientists/.</p>

<p>Join us! Visit our Careers page (www.23andMe.com/careers) to learn more<br />about these open positions:</p>

<p>•	Scientist, Research Communications<br />•	Bioinformaticist<br />•	Computational Biologist, Ancestry R&amp;D<br />•	Scientist/Senior Scientist, Statistical Genetics<br />•	Scientist/Senior Scientist, Survey Methodology<br />•	Scientist/Senior Scientist, Health R&amp;D<br />•	Senior Computational Biologist<br />•	Biostatistician</p>

<p>pfontanillas@23andme.com</p>
]]></description>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/32716/jrfsrf-project-assistant-ii-recruitment-in-national-agri-food-biotechnology-institute-nabi</guid>
  <pubDate>Mon, 15 May 2017 05:37:52 -0500</pubDate>
  <link></link>
  <title><![CDATA[JRF/SRF / Project Assistant-II recruitment in National Agri-Food Biotechnology Institute (NABI)]]></title>
  <description><![CDATA[
<p>National Agri-Food Biotechnology Institute<br />ADVT. No: 2017-Researcher (02)</p>

<p>JRF/SRF / Project Assistant-II recruitment in National Agri-Food Biotechnology Institute (NABI)</p>

<p>Essential Qualification: According to the DST (DST OM No.SR/S9/Z-09/2012 dated 21.10.2014) Post Graduate degree in basic science(M.Sc) in Bioinformatics/Computational Biology/Systems Biology/Information Technology with NET or Graduate degree in professional course with NET or Post Graduate Degree (M.Tech) in professional course in Bioinformatics/Computational Biology/Systems Biology/Information Technology. Desirable qualification/skills: 1) Should be proficient in programming in Perl/Python/R language etc. 2) Should have knowledge and skills for data mining in biological sequence database . sequence analysis tools/packages, NGS Analysis . 3) Should have knowledge and skills to work in linux environment and write shell scripts.</p>

<p>Age : 28 years</p>

<p>Hiring Process : Written-test<br />Job Role : Research/JRF/SRF<br />How to apply</p>

<p>Application should be sent to Administrative officer, National Agri-Food Biotechnology Institute, Knowledge City, Sector-81, Mohali so as to reach latest by 30.05.2017 before 5:30 pm.</p>

<p>More at http://www.nabi.res.in/Vacancies/NABI/ResearchFellowships/JRFSRFRA/2017/ADVT.%20No%202017Researcher%20(02)/ApplicationForm.pdf</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/33856/assembly-course</guid>
	<pubDate>Mon, 10 Jul 2017 09:38:05 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/33856/assembly-course</link>
	<title><![CDATA[Assembly Course]]></title>
	<description><![CDATA[<p>https://ocw.mit.edu/courses/biology/7-91j-foundations-of-computational-and-systems-biology-spring-2014/lecture-slides/MIT7_91JS14_Lecture6.pdf</p><p>Address of the bookmark: <a href="https://ocw.mit.edu/courses/biology/7-91j-foundations-of-computational-and-systems-biology-spring-2014/lecture-slides/MIT7_91JS14_Lecture6.pdf" rel="nofollow">https://ocw.mit.edu/courses/biology/7-91j-foundations-of-computational-and-systems-biology-spring-2014/lecture-slides/MIT7_91JS14_Lecture6.pdf</a></p>]]></description>
	<dc:creator>Shruti Paniwala</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/34814/bioinformatics-web-application-development-with-perl</guid>
	<pubDate>Tue, 26 Dec 2017 18:14:11 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/34814/bioinformatics-web-application-development-with-perl</link>
	<title><![CDATA[Bioinformatics Web Application Development with Perl]]></title>
	<description><![CDATA[<div><p>Perl's second wave of adoption came from the growth of the world wide web. Dynamic web pages&mdash;the precursor to modern web applications&mdash;were easy to create with Perl and CGI. Thanks to Perl's ubiquity as a language for system administrators and its power to manipulate text, it was the default choice for web programming. Its presence everywhere made it popular and, in some ways, the duct tape of the Internet.</p><h4>Web Application Development</h4><p>The old days of CGI programs and the simple development style that represented seem clunky. Web pages have become web applications. Development has moved from generating static HTML to both client and server side programming, with rich client interfaces and powerful backends.</p><p>Perl is still well suited for developing modern web apps. The language grows more powerful and easier to use every year, the available libraries are wonderful and keep getting better, and the inventions and discoveries available in modern Perl are unsurpassed.</p><p>In particular, a modern Perl developer can do amazing things with modern Perl tools. If you still think of Perl web development as a&nbsp;<em>cgi-bin</em>&nbsp;directory full of messy scripts that spew warnings to STDERR, you're a decade out of date. Better yet, you can replace that mess piecemeal, thanks to the new tools and techniques of modern Perl. See, for example, the ever-growing list of technologies&nbsp;<a href="http://www.builtinperl.com/">Built in Perl</a>.</p><h4>Modern Perl Web Frameworks</h4><p>While the old wave of web development may have made the CGI.pm module central, modern Perl web programming follows a stricter separation of business logic, URL and request routing, and output. The days of slinging a string here, an array there, a Perl hash yonder, declaring every variable at the top of the program, and maybe making a subroutine are gone. The Perl world has seen the value of abstraction and ways to mechanize away boilerplate. Perl has dozens of frameworks and toolkits designed to make web development and deployment simpler.</p><p>Any of a dozen of these frameworks will help you do great things, but three in particular stand out. You can build web sites and web applications of tremendous value with all three. These are neither the only good possibilities (think of POE or Jifty or Continuity or...) nor the only mechanisms for web programming with Perl (see Mechanize or LWP or Mojo::UserAgent for more). Yet if you want three good options to choose between, start here.</p><h4>Catalyst</h4><p>The&nbsp;<a href="http://catalystframework.org/">Catalyst</a>&nbsp;framework is a flexible and powerful system for building small to large web apps. It uses the&nbsp;<a href="http://moose.perl.org/">Moose</a>&nbsp;object system to provide great APIs for extension and further development. It's the most mature of the modern top Perl web frameworks, yet it retains its flexibility and vibrancy. In particular, its plugin and extension ecosystem allows it to evolve to provide new and essential features.</p><p>Catalyst has embraced the Plack/PSGI standard for Perl web deployment and recent versions are exploring high-scalability, event-based request handling models.</p><h4>Dancer</h4><p>The&nbsp;<a href="http://perldancer.org/">Dancer</a>&nbsp;framework is deliberately minimal in syntax and scope, but it also has a vibrant plugin ecosystem. Dancer particularly excels for smaller sites and applications, though good programmers can build larger things with it.</p><p>The first version of Dancer was easy to use. Dancer 2 continues that ease while improving the internals and robustness of applications.</p><h4>Mojolicious</h4><p>The&nbsp;<a href="http://mojolicio.us/">Mojolicious</a>&nbsp;(Mojo) framework has a real-time design based on high performance event handling. Its focus is solving new and interesting problems in simple and effective ways, and the project has produced a lot of new code that does old things in better ways.</p><p>In particular, Mojolicious goes to great lengths to support new web standards, such as CSS 3, web sockets, and HTTP 2.</p><p>Where Catalyst embraces the CPAN fully, Mojolicious by design provides most of what an average app might need in a single download. It's still fully compatible with the CPAN, but the intention is to provide good working defaults in a package that's easy to start with. Mojo's fans are quick to praise it as fun to develop.</p><p>A modern Perl web developer should be familiar with at least one of these frameworks.</p><h4>Modern Perl Storage Mechanisms</h4><p>Perl's venerable&nbsp;<a href="http://search.cpan.org/perldoc?DBI">DBI</a>&nbsp;module has been the focal point of database access since its invention. Its design allows it to provide the same interface to huge relational databases and flat files alike through its DBD extension mechanism. Yet the DBI by itself isn't the be-all, end-all of data storage and access in Perl.</p><h4>DBIx::Class</h4><p><a href="http://search.cpan.org/perldoc?DBIx::Class">DBIx::Class</a>&nbsp;sits on top of DBI to provide an API to your database based on the concept of queries and results. This is often sufficient to remove all but the most complicated of SQL from your code, leaving you to manipulate your business models instead of the small details of how a relational database works. The power and maintainability you receive is well the small cost of the learning curve.</p><p>Even better, DBIC can manage (and even generate) your database schema for you.</p><p>Recent versions of DBIC have demonstrated that a well-written ORM can perform much better than even clever hand-written code. Because it builds on the Perl DBI, it scales everywhere from SQLite to PostgreSQL, MySQL, Oracle, and more.</p><h3>Rose::DB</h3><p>The lesser-known but no less powerful&nbsp;<a href="http://search.cpan.org/perldoc?Rose::DB::Object">Rose::DB::Object</a>&nbsp;builds on&nbsp;<a href="http://search.cpan.org/perldoc?Rose::DB">Rose::DB</a>&nbsp;to provide an object-relational mapper for Perl. While its high level features most directly compare to those of DBIx::Class, it's often measurably faster.</p><h4>NoSQL on the CPAN</h4><p>Of course the&nbsp;<a href="http://search.cpan.org/">CPAN</a>&nbsp;has modules for almost any NoSQL database or job queue or persistence mechanism you could name, and several you have never heard of. Everything you need is a quick CPAN or cpanm away!</p><h4>Modern Perl Deployment Strategies</h4><p>In the early days of the web, deploying a Perl web application meant putting one or more&nbsp;<em>.cgi</em>&nbsp;or&nbsp;<em>.pl</em>&nbsp;files in a special directory and hoping that your system administrator had everything configured correctly. The execution model was often slow and cumbersome, and accessing shared resources such as databases was often tricky.</p><p>Modern Perl has better choices. While deployment strategies are the source of many arguments, the return on your investment from learning the modern way is impressive.</p><h4>Plack/PSGI</h4><p>The PSGI specification (as exemplified by&nbsp;<a href="http://plackperl.org/">Plack</a>) describes a strategy for building Perl web apps independent of server and with the possibility to share custom processing behaviors.</p><p>In other words, it's a standard for writing Perl apps to take advantage of the huge ecosystem of Perl development available on the CPAN without tying yourself to a server like Apache, Apache 2, nginx, or anything else.</p><p>Any good modern Perl web framework (including those listed here) supports PSGI. Several deployment mechanisms exist to meet various business needs which also support PSGI. In particular, you can deploy the same application with a local testing server on your own machine as you can to your production server or servers without changing your application at all.</p><h4>mod_perl</h4><p>The older but still viable mod_perl Apache httpd module embeds Perl into the web server. This was the first widespread persistence mechanism for Perl web applications themselves and it's still popular to this day, though PSGI compliance is often the choice for new development. (PSGI handlers to use mod_perl as the backend are available.)</p><p>Modern Perl developers should familiarize themselves with PSGI and the wealth of available Plack middleware.</p><h4>Perl Web Development</h4><p>Of course no discussion of Perl web development would be complete without mentioning the strength of the CPAN. Almost any project will benefit from the wealth of freely available libraries built to solve real problems. These distributions run the gamut from full-blown web frameworks and content management systems to APIs for web services, development tools, testing systems, and interfaces to document formats and external resources.</p><p>For example, if you need to write a web service which accepts JSON data and produces Excel spreadsheets, you can glue together a few CPAN distributions and get the job done early. If you need to consume XML from a remote service and emit a PDF, you're in luck.</p><p>Perl's prowess as a general purpose programming language as well as its flexibility and power in managing text and gluing systems together make it a wonderful fit for web development. The community's adoption of modern Perl standards such as PSGI and Plack only enhance your power.</p><p>Web application development in Perl is still viable, and modern Perl tools and techniques and libraries make it more powerful and pleasant than ever.</p></div>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36893/beap-blast-extension-and-assembly-program</guid>
	<pubDate>Mon, 11 Jun 2018 04:52:56 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36893/beap-blast-extension-and-assembly-program</link>
	<title><![CDATA[BEAP: Blast Extension and Assembly Program]]></title>
	<description><![CDATA[The Blast Extension and Assembly Program (BEAP) is a computer program that uses a short starting DNA fragment, often a EST or partial gene segment, as "primer", to recursively blast nucleotide databases in an attempt to obtain all sequences that overlaps, directly or indirectly, with the "primer" therefore help to "extend" the length of the original sequence for constructing a "full length" sequence for functional analysis, or at least to obtain neighboring regions of the segment for SNP discovery and linkage disequilibrium analysis. The confidence of assembling the resulting sequences is achieved by using a known genome, such as human genome, as a reference.
 
https://www.animalgenome.org/tools/beap/<p>Address of the bookmark: <a href="https://www.animalgenome.org/tools/beap/" rel="nofollow">https://www.animalgenome.org/tools/beap/</a></p>]]></description>
	<dc:creator>Shruti Paniwala</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/35525/linux-commands-cheat-sheet-for-bioinformatics-and-computational-biology-professionals</guid>
	<pubDate>Mon, 05 Feb 2018 18:50:41 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/35525/linux-commands-cheat-sheet-for-bioinformatics-and-computational-biology-professionals</link>
	<title><![CDATA[Linux Commands Cheat Sheet for Bioinformatics and Computational Biology Professionals]]></title>
	<description><![CDATA[<p><span>The purpose of this cheat sheet is to introduce biologist and bioinformatician to the frequently used tools for NGS analysis as well as giving experience in writing one-liners.</span></p><ul>
<li><span></span><span><strong>File System</strong></span><span><strong><br /> </strong></span><span>ls</span><span>&nbsp;&mdash; list items in current directory</span><span><br /> </span><span>ls -l</span><span>&nbsp;&mdash; list items in current directory and show in long format to see perimissions, size, and modification date</span><span><br /> </span><span>ls -a</span><span>&nbsp;&mdash; list all items in current directory, including hidden files</span><span><br /> </span><span>ls -F</span><span>&nbsp;&mdash; list all items in current directory and show directories with a slash and executables with a star</span><span><br /> </span><span>ls dir</span><span>&nbsp;&mdash; list all items in directory dir</span><span><br /> </span><span>cd dir</span><span>&nbsp;&mdash; change directory to dir</span><span><br /> </span><span>cd ..</span><span>&nbsp;&mdash; go up one directory</span><span><br /> </span><span>cd /</span><span>&nbsp;&mdash; go to the root directory</span><span><br /> </span><span>cd ~</span><span>&nbsp;&mdash; go to to your home directory</span><span><br /> </span><span>cd -</span><span>&nbsp;&mdash; go to the last directory you were just in</span><span><br /> </span><span>pwd</span><span>&nbsp;&mdash; show present working directory</span><span><br /> </span><span>mkdir dir</span><span>&nbsp;&mdash; make directory dir</span><span><br /> </span><span>rm file</span><span>&nbsp;&mdash; remove file</span><span><br /> </span><span>rm -r dir</span><span>&nbsp;&mdash; remove directory dir recursively</span><span><br /> </span><span>cp file1 file2</span><span>&nbsp;&mdash; copy file1 to file2</span><span><br /> </span><span>cp -r dir1 dir2</span><span>&nbsp;&mdash; copy directory dir1 to dir2 recursively</span><span><br /> </span><span>mv file1 file2</span><span>&nbsp;&mdash; move (rename) file1 to file2</span><span><br /> </span><span>ln -s file link</span><span>&nbsp;&mdash; create symbolic link to file</span><span><br /> </span><span>touch file</span><span>&nbsp;&mdash; create or update file</span><span><br /> </span><span>cat file</span><span>&nbsp;&mdash; output the contents of file</span><span><br /> </span><span>less file</span><span>&nbsp;&mdash; view file with page navigation</span><span><br /> </span><span>head file</span><span>&nbsp;&mdash; output the first 10 lines of file</span><span><br /> </span><span>tail file</span><span>&nbsp;&mdash; output the last 10 lines of file</span><span><br /> </span><span>tail -f file</span><span>&nbsp;&mdash; output the contents of file as it grows, starting with the last 10 lines</span><span><br /> </span><span>vim file</span><span>&nbsp;&mdash; edit file</span><span><br /> </span><span>alias name 'command'</span><span>&nbsp;&mdash; create an alias for a command</span><span><br /> </span></li>
<li><span></span><span><strong>System</strong></span><span><strong><br /> </strong></span><span>shutdown</span><span>&nbsp;&mdash; shut down machine</span><span><br /> </span><span>reboot</span><span>&nbsp;&mdash; restart machine</span><span><br /> </span><span>date</span><span>&nbsp;&mdash; show the current date and time</span><span><br /> </span><span>whoami</span><span>&nbsp;&mdash; who you are logged in as</span><span><br /> </span><span>finger user</span><span>&nbsp;&mdash; display information about user</span><span><br /> </span><span>man command</span><span>&nbsp;&mdash; show the manual for command</span><span><br /> </span><span>df</span><span>&nbsp;&mdash; show disk usage</span><span><br /> </span><span>du</span><span>&nbsp;&mdash; show directory space usage</span><span><br /> </span><span>free</span><span>&nbsp;&mdash; show memory and swap usage</span><span><br /> </span><span>whereis app</span><span>&nbsp;&mdash; show possible locations of app</span><span><br /> </span><span>which app</span><span>&nbsp;&mdash; show which app will be run by default</span><span><br /> </span></li>
<li><span></span><span><strong>Process Management</strong></span><span><strong><br /> </strong></span><span>ps</span><span>&nbsp;&mdash; display your currently active processes</span><span><br /> </span><span>top</span><span>&nbsp;&mdash; display all running processes</span><span><br /> </span><span>kill pid</span><span>&nbsp;&mdash; kill process id pid</span><span><br /> </span><span>kill -9 pid</span><span>&nbsp;&mdash; force kill process id pid</span><span><br /> </span></li>
<li><span></span><span><strong>Permissions</strong></span><span><strong><br /> </strong></span><span>ls -l</span><span>&nbsp;&mdash; list items in current directory and show permissions</span><span><br /> </span><span>chmod ugo file</span><span>&nbsp;&mdash; change permissions of file to ugo - u is the user's permissions, g is the group's permissions, and o is everyone else's permissions. The values of u, g, and o can be any number between 0 and 7.</span><span><br /> </span><span>7</span><span>&nbsp;&mdash; full permissions</span><span><br /> </span><span>6</span><span>&nbsp;&mdash; read and write only</span><span><br /> </span><span>5</span><span>&nbsp;&mdash; read and execute only</span><span><br /> </span><span>4</span><span>&nbsp;&mdash; read only</span><span><br /> </span><span>3</span><span>&nbsp;&mdash; write and execute only</span><span><br /> </span><span>2</span><span>&nbsp;&mdash; write only</span><span><br /> </span><span>1</span><span>&nbsp;&mdash; execute only</span><span><br /> </span><span>0</span><span>&nbsp;&mdash; no permissions</span><span><br /> </span><span>chmod 600 file</span><span>&nbsp;&mdash; you can read and write - good for files</span><span><br /> </span><span>chmod 700 file</span><span>&nbsp;&mdash; you can read, write, and execute - good for scripts</span><span><br /> </span><span>chmod 644 file</span><span>&nbsp;&mdash; you can read and write, and everyone else can only read - good for web pages</span><span><br /> </span><span>chmod 755 file</span><span>&nbsp;&mdash; you can read, write, and execute, and everyone else can read and execute - good for programs that you want to share</span><span><br /> </span></li>
<li><span></span><span><strong>Networking</strong></span><span><strong><br /> </strong></span><span>wget file</span><span>&nbsp;&mdash; download a file</span><span><br /> </span><span>curl file</span><span>&nbsp;&mdash; download a file</span><span><br /> </span><span>scp user@host:file dir</span><span>&nbsp;&mdash; secure copy a file from remote server to the dir directory on your machine</span><span><br /> </span><span>scp file user@host:dir</span><span>&nbsp;&mdash; secure copy a file from your machine to the dir directory on a remote server</span><span><br /> </span><span>scp -r user@host:dir dir</span><span>&nbsp;&mdash; secure copy the directory dir from remote server to the directory dir on your machine</span><span><br /> </span><span>ssh user@host</span><span>&nbsp;&mdash; connect to host as user</span><span><br /> </span><span>ssh -p port user@host</span><span>&nbsp;&mdash; connect to host on port as user</span><span><br /> </span><span>ssh-copy-id user@host</span><span>&nbsp;&mdash; add your key to host for user to enable a keyed or passwordless login</span><span><br /> </span><span>ping host</span><span>&nbsp;&mdash; ping host and output results</span><span><br /> </span><span>whois domain</span><span>&nbsp;&mdash; get information for domain</span><span><br /> </span><span>dig domain</span><span>&nbsp;&mdash; get DNS information for domain</span><span><br /> </span><span>dig -x host</span><span>&nbsp;&mdash; reverse lookup host</span><span><br /> </span><span>lsof -i tcp:1337</span><span>&nbsp;&mdash; list all processes running on port 1337</span><span><br /> </span></li>
<li><span></span><span><strong>Searching</strong></span><span><strong><br /> </strong></span><span>grep pattern files</span><span>&nbsp;&mdash; search for pattern in files</span><span><br /> </span><span>grep -r pattern dir</span><span>&nbsp;&mdash; search recursively for pattern in dir</span><span><br /> </span><span>grep -rn pattern dir</span><span>&nbsp;&mdash; search recursively for pattern in dir and show the line number found</span><span><br /> </span><span>grep -r pattern dir --include='*.ext</span><span>&nbsp;&mdash; search recursively for pattern in dir and only search in files with .ext extension</span><span><br /> </span><span>command | grep pattern</span><span>&nbsp;&mdash; search for pattern in the output of command</span><span><br /> </span><span>find file</span><span>&nbsp;&mdash; find all instances of file in real system</span><span><br /> </span><span>locate file</span><span>&nbsp;&mdash; find all instances of file using indexed database built from the updatedb command. Much faster than find</span><span><br /> </span><span>sed -i 's/day/night/g' file</span><span>&nbsp;&mdash; find all occurrences of day in a file and replace them with night - s means substitude and g means global - sed also supports regular expressions</span><span><br /> </span></li>
<li><span></span><span><strong>Compression</strong></span><span><strong><br /> </strong></span><span>tar cf file.tar files</span><span>&nbsp;&mdash; create a tar named file.tar containing files</span><span><br /> </span><span>tar xf file.tar</span><span>&nbsp;&mdash; extract the files from file.tar</span><span><br /> </span><span>tar czf file.tar.gz files</span><span>&nbsp;&mdash; create a tar with Gzip compression</span><span><br /> </span><span>tar xzf file.tar.gz</span><span>&nbsp;&mdash; extract a tar using Gzip</span><span><br /> </span><span>gzip file</span><span>&nbsp;&mdash; compresses file and renames it to file.gz</span><span><br /> </span><span>gzip -d file.gz</span><span>&nbsp;&mdash; decompresses file.gz back to file</span><span><br /> </span></li>
<li><span></span><span><strong>Shortcuts</strong></span><span><strong><br /> </strong></span><span>ctrl+a</span><span>&nbsp;&mdash; move cursor to beginning of line</span><span><br /> </span><span>ctrl+f</span><span>&nbsp;&mdash; move cursor to end of line</span><span><br /> </span><span>alt+f</span><span>&nbsp;&mdash; move cursor forward 1 word</span><span><br /> </span><span>alt+b</span><span>&nbsp;&mdash; move cursor backward 1 word</span><span><br /> </span></li>
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</ul>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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