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<channel>
	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/32853?offset=50</link>
	<atom:link href="https://bioinformaticsonline.com/related/32853?offset=50" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42405/caretta-%E2%80%93-a-multiple-protein-structure-alignment-and-feature-extraction-suite</guid>
	<pubDate>Fri, 18 Dec 2020 02:09:44 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42405/caretta-%E2%80%93-a-multiple-protein-structure-alignment-and-feature-extraction-suite</link>
	<title><![CDATA[Caretta – A multiple protein structure alignment and feature extraction suite]]></title>
	<description><![CDATA[<h3>Caretta &ndash;&nbsp;a multiple protein structure alignment and feature extraction suite</h3>
<p><span>Caretta, a multiple structure alignment suite meant for homologous but sequentially divergent protein families which consistently returns accurate alignments with a higher coverage than current state-of-the-art tools. Caretta is available as a GUI and command-line application and additionally outputs an aligned structure feature matrix for a given set of input structures, which can readily be used in downstream steps for supervised or unsupervised machine learning.&nbsp;</span></p><p>Address of the bookmark: <a href="http://www.bioinformatics.nl/caretta/" rel="nofollow">http://www.bioinformatics.nl/caretta/</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/33942/mulan-multiple-sequence-local-alignment-and-conservation-visualization-tool</guid>
	<pubDate>Thu, 20 Jul 2017 08:02:32 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/33942/mulan-multiple-sequence-local-alignment-and-conservation-visualization-tool</link>
	<title><![CDATA[Mulan: MUltiple sequence Local AligNment and conservation visualization tool]]></title>
	<description><![CDATA[<p><span>Mulan performs multiple (2 or more) sequence alignments with an efficient and rapid "full local" alignment strategy that ensures a recapitulation of evolutionary sequence rearrangements (such as inversions and reshuffling) in any of the species. It combines&nbsp;</span><a href="http://www.bx.psu.edu/miller_lab/" target="_new"><em>refine</em>&nbsp;and&nbsp;<em>tba</em></a><span>&nbsp;tools to align either "draft" or "finished" quality sequences. Mulan provides a dynamic graphical interface to align and visualize conservation profiles for evolutionarily distant and closely related species.</span><br><span></span></p>
<p><span>Input formats, automated data upload from the&nbsp;</span><a href="http://genome.ucsc.edu/" target="_new">UCSC Genome Browser</a><span>, gene annotation, annotation of repetitive elements, and progress report were previously described in the&nbsp;</span><a href="https://zpicture.dcode.org/zpInstructions.html" target="_zp">zPicture instructions</a><span>&nbsp;and we refer the users to these materials for more details. This introduction is mainly focused on some novel features unique to the Mulan.</span><span><br></span></p><p>Address of the bookmark: <a href="https://mulan.dcode.org/mulanInstructions.php" rel="nofollow">https://mulan.dcode.org/mulanInstructions.php</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/21241/pacman</guid>
	<pubDate>Mon, 16 Feb 2015 12:15:17 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/21241/pacman</link>
	<title><![CDATA[Pacman]]></title>
	<description><![CDATA[<p><span>The pacman package is an R package management tool that combines the functionality of base library related functions into intuitively named functions. This package is ideally added to .Rprofile to increase workflow by reducing time recalling obscurely named functions, reducing code and integrating functionality of base functions to simultaneously perform multiple actions.<br /><br />Function names in the pacman package follow the format of p_xxx where &lsquo;xxx&rsquo; is the task the function performs. For instance the p_load function allows the user to load one or more packages as a more generic substitute for the library or require functions and if the package isn&rsquo;t available locally it will install it for you.<br /><br /></span></p><p><strong>Installation</strong></p><p><span>To download the development version of pacman:</span></p><p><span>Download the </span><a href="https://github.com/trinker/pacman/zipball/master">zip ball</a><span> or </span><a href="https://github.com/trinker/pacman/tarball/master">tar ball</a><span>, decompress and run </span><code>R CMD INSTALL</code><span> on it, or use th</span><span>e </span><strong>devtools</strong><span> package to install the development version:</span></p><pre title="">## Make sure your current packages are up to date
update.packages()
## devtools is required
devtools::install_github("trinker/pacman")
</pre><p>Note: Windows users need <a href="http://www.murdoch-sutherland.com/Rtools/">Rtools</a> and <a href="http://CRAN.R-project.org/package=devtools">devtools</a> to install this way.</p><p>More at https://github.com/trinker/pacman</p><p>&nbsp;</p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27850/clusterprofiler</guid>
	<pubDate>Thu, 16 Jun 2016 18:57:03 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27850/clusterprofiler</link>
	<title><![CDATA[clusterProfiler]]></title>
	<description><![CDATA[<p>statistical analysis and visulization of functional profiles for genes and gene clusters<br><br>Bioconductor version: Release (3.3)<br><br>This package implements methods to analyze and visualize functional profiles (GO and KEGG) of gene and gene clusters.<br><br>Author: Guangchuang Yu &lt;guangchuangyu at gmail.com&gt; with contributions from Li-Gen Wang and Giovanni Dall'Olio.<br><br>Maintainer: Guangchuang Yu &lt;guangchuangyu at gmail.com&gt;<br><br>Citation (from within R, enter citation("clusterProfiler")):<br><br>Yu G, Wang L, Han Y and He Q (2012). &ldquo;clusterProfiler: an R package for comparing biological themes among gene clusters.&rdquo; OMICS: A Journal of Integrative Biology, 16(5), pp. 284-287.<br>Installation<br><br>To install this package, start R and enter:<br><br>## try http:// if https:// URLs are not supported<br>source("https://bioconductor.org/biocLite.R")<br>biocLite("clusterProfiler")</p>
<p>https://www.bioconductor.org/packages/devel/bioc/vignettes/clusterProfiler/inst/doc/clusterProfiler.html</p><p>Address of the bookmark: <a href="https://www.bioconductor.org/packages/devel/bioc/vignettes/clusterProfiler/inst/doc/clusterProfiler.html" rel="nofollow">https://www.bioconductor.org/packages/devel/bioc/vignettes/clusterProfiler/inst/doc/clusterProfiler.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41169/instructions-for-creating-your-own-r-package</guid>
	<pubDate>Wed, 19 Feb 2020 01:22:48 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41169/instructions-for-creating-your-own-r-package</link>
	<title><![CDATA[Instructions for Creating Your Own R Package]]></title>
	<description><![CDATA[<p>The following is a step-by-step guide to creating your own R package.&nbsp; Even beyond this course, youmay find this useful for storing functions you create for your own research or for editing existingR packages to suit your needs.</p>
<p>This guide contains three different sets of instructions.&nbsp; If you use RStudio, you can follow the &ldquo;Ba-sic Instructions&rdquo; in Section 2 which involve using RStudio&rsquo;s interface.&nbsp; </p><p>Address of the bookmark: <a href="http://web.mit.edu/insong/www/pdf/rpackage_instructions.pdf" rel="nofollow">http://web.mit.edu/insong/www/pdf/rpackage_instructions.pdf</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34396/pore-an-r-package-for-the-visualization-and-analysis-of-nanopore-sequencing-data</guid>
	<pubDate>Thu, 23 Nov 2017 09:55:57 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34396/pore-an-r-package-for-the-visualization-and-analysis-of-nanopore-sequencing-data</link>
	<title><![CDATA[poRe: an R package for the visualization and analysis of nanopore sequencing data]]></title>
	<description><![CDATA[<p><strong>Motivation:</strong>&nbsp;The Oxford Nanopore MinION device represents a unique sequencing technology. As a mobile sequencing device powered by the USB port of a laptop, the MinION has huge potential applications. To enable these applications, the bioinformatics community will need to design and build a suite of tools specifically for MinION data.</p>
<p><strong>Results:</strong>&nbsp;Here we present poRe, a package for R that enables users to manipulate, organize, summarize and visualize MinION nanopore sequencing data. As a package for R, poRe has been tested on Windows, Linux and MacOSX. Crucially, the Windows version allows users to analyse MinION data on the Windows laptop attached to the device.</p>
<p><strong>Availability and implementation:</strong>&nbsp;poRe is released as a package for R at&nbsp;<a href="http://sourceforge.net/projects/rpore/" target="">http://sourceforge.net/projects/rpore/</a>&nbsp;. A tutorial and further information are available at&nbsp;<a href="https://sourceforge.net/p/rpore/wiki/Home/" target="">https://sourceforge.net/p/rpore/wiki/Home/</a></p>
<p><strong>Contact:</strong><a href="mailto:mick.watson@roslin.ed.ac.uk" target="">mick.watson@roslin.ed.ac.uk</a></p><p>Address of the bookmark: <a href="https://academic.oup.com/bioinformatics/article/31/1/114/2365693" rel="nofollow">https://academic.oup.com/bioinformatics/article/31/1/114/2365693</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38646/visnetwork-an-r-package-for-network-visualization-using-visjs-javascript-library</guid>
	<pubDate>Wed, 09 Jan 2019 11:00:32 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38646/visnetwork-an-r-package-for-network-visualization-using-visjs-javascript-library</link>
	<title><![CDATA[visNetwork: an R package for network visualization, using vis.js javascript library]]></title>
	<description><![CDATA[<div id="introduction">
<p><strong>visNetwork</strong>&nbsp;is an R package for network visualization, using&nbsp;<strong>vis.js</strong>&nbsp;javascript library (<a href="http://visjs.org/">http://visjs.org/</a>). All remarks and bugs are welcome on github :&nbsp;<a href="https://github.com/datastorm-open/visNetwork">https://github.com/datastorm-open/visNetwork</a>.</p>
</div>
<div id="features">
<h2>Features</h2>
<p>Based on&nbsp;<a href="http://www.htmlwidgets.org/">htmlwidgets</a>, so :</p>
<ul>
<li>compatible with&nbsp;<a href="http://shiny.rstudio.com/">shiny</a>, R Markdown documents, and RStudio viewer</li>
</ul>
<p>The package proposes all the features available in&nbsp;<strong>vis.js</strong>&nbsp;API, and even more with special features for R :</p>
<ul>
<li>easy to use</li>
<li>custom shapes, styles, colors, sizes, &hellip;</li>
<li>works smooth on any modern browser for up to a few thousand nodes and edges</li>
<li>interactivity controls (highlight, collapsed nodes, selection, zoom, physics, movement of nodes, tooltip, events, &hellip;)</li>
<li>visualize&nbsp;<code>rpart</code>&nbsp;tree</li>
<li></li>
</ul>
</div><p>Address of the bookmark: <a href="https://datastorm-open.github.io/visNetwork/" rel="nofollow">https://datastorm-open.github.io/visNetwork/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39114/plumberan-r-package-that-converts-your-existing-r-code-to-a-web-api</guid>
	<pubDate>Wed, 13 Mar 2019 19:20:10 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39114/plumberan-r-package-that-converts-your-existing-r-code-to-a-web-api</link>
	<title><![CDATA[plumber:An R package that converts your existing R code to a web API]]></title>
	<description><![CDATA[<p>plumber allows you to create a REST API by merely decorating your existing R source code with special comments. Take a look at an example.</p>
<pre><code><span># plumber.R
</span><span>
</span><span>#* Echo back the input
#* @param msg The message to echo
#* @get /echo
</span><span>function</span><span>(</span><span>msg</span><span>=</span><span>""</span><span>){</span><span>
  </span><span>list</span><span>(</span><span>msg</span><span> </span><span>=</span><span> </span><span>paste0</span><span>(</span><span>"The message is: '"</span><span>,</span><span> </span><span>msg</span><span>,</span><span> </span><span>"'"</span><span>))</span><span>
</span><span>}</span><span>

</span><span>#* Plot a histogram
#* @png
#* @get /plot
</span><span>function</span><span>(){</span><span>
  </span><span>rand</span><span> </span><span>&lt;-</span><span> </span><span>rnorm</span><span>(</span><span>100</span><span>)</span><span>
  </span><span>hist</span><span>(</span><span>rand</span><span>)</span><span>
</span><span>}</span><span>

</span><span>#* Return the sum of two numbers
#* @param a The first number to add
#* @param b The second number to add
#* @post /sum
</span><span>function</span><span>(</span><span>a</span><span>,</span><span> </span><span>b</span><span>){</span><span>
  </span><span>as.numeric</span><span>(</span><span>a</span><span>)</span><span> </span><span>+</span><span> </span><span>as.numeric</span><span>(</span><span>b</span><span>)</span><span>
</span><span>}</span></code></pre><p>Address of the bookmark: <a href="https://www.rplumber.io/" rel="nofollow">https://www.rplumber.io/</a></p>]]></description>
	<dc:creator>BioJoker</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/40596/igblast-a-popular-ncbi-package-for-classifying-and-analyzing-immunoglobulin-ig-and-t-cell-receptor-tcr-variable-domain-sequences</guid>
	<pubDate>Thu, 23 Jan 2020 11:34:37 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/40596/igblast-a-popular-ncbi-package-for-classifying-and-analyzing-immunoglobulin-ig-and-t-cell-receptor-tcr-variable-domain-sequences</link>
	<title><![CDATA[IgBLAST: a popular NCBI package for classifying and analyzing immunoglobulin (IG) and T cell receptor (TCR) variable domain sequences]]></title>
	<description><![CDATA[<p>NCBI team released a new version of IgBLAST with four new improvements. IgBLAST is a popular NCBI package for classifying and analyzing immunoglobulin (IG) and T cell receptor (TCR) variable domain sequences. Improvements are:<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>&nbsp;&nbsp;&nbsp; 1. Support for the new FWR4 annotation feature in the AIRR format, both in standard format and in the AIRR alignment format.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>&nbsp;&nbsp;&nbsp; 2. The previous &ldquo;-penalty&rdquo; parameter was renamed as -V_penalty to be consistent with other IgBLAST penalty options.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>&nbsp;&nbsp;&nbsp; 3. Restored constant internal BLAST search parameters for domain annotation (i.e., FWR/CDR) such that this process is not influenced by user parameters.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>&nbsp;&nbsp;&nbsp; 4. Corrected FWR/CDR annotations for certain mouse VK and rat VH germline genes.<span style="font-size: 12.8px;">&nbsp;</span></p><p><span style="text-decoration: underline;"></span></p><p>IgBLAST 1.15.0 is available for&nbsp;<a href="https://ftp.ncbi.nih.gov/blast/executables/igblast/release/LATEST/" target="_blank">download</a>&nbsp;from the BLAST FTP area. See the the new&nbsp;<a href="https://ncbi.github.io/igblast/" target="_blank">manual</a>&nbsp;on GitHub for information about setting up and running IgBLAST.</p><p><span style="text-decoration: underline;"></span></p><p>&nbsp;If you have any questions or concerns, please contact&nbsp;<a href="mailto:blast-help@ncbi.nlm.nih.gov" target="_blank" title="Follow link">blast-help@ncbi.nlm.nih.gov</a><span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p><span style="text-decoration: underline;"></span>&nbsp;</p>]]></description>
	<dc:creator>BioJoker</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42012/phewas-r-package-is-designed-to-provide-an-accessible-interface-to-the-phenome-wide-association-study</guid>
	<pubDate>Thu, 30 Jul 2020 22:06:37 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42012/phewas-r-package-is-designed-to-provide-an-accessible-interface-to-the-phenome-wide-association-study</link>
	<title><![CDATA[PheWAS: R package is designed to provide an accessible interface to the phenome wide association study]]></title>
	<description><![CDATA[<p>The PheWAS R package is designed to provide an accessible interface to the phenome wide association study. For a description of the methods available and some simple examples, please see the&nbsp;<a href="https://github.com/PheWAS/PheWAS/blob/master/inst/doc/PheWAS-package.pdf?raw=true">package vignette</a>&nbsp;or the R documentation. For installation help, see below. ##Installing the PheWAS Package The PheWAS package can be installed using the devtools package. The following code when executed in R will get you started:</p>
<pre><code>install.packages("devtools")
#It may be necessary to install required as not all package dependencies are installed by devtools:
install.packages(c("dplyr","tidyr","ggplot2","MASS","meta","ggrepel","DT"))
devtools::install_github("PheWAS/PheWAS")
library(PheWAS)</code></pre><p>Address of the bookmark: <a href="https://github.com/PheWAS/PheWAS" rel="nofollow">https://github.com/PheWAS/PheWAS</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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