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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/34685?offset=450</link>
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	<description><![CDATA[]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31156/splitbam-splits-a-bam-by-chromosomes</guid>
	<pubDate>Tue, 28 Feb 2017 09:01:28 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31156/splitbam-splits-a-bam-by-chromosomes</link>
	<title><![CDATA[splitbam: splits a BAM by chromosomes]]></title>
	<description><![CDATA[<p><strong>splitbam</strong>&nbsp;splits a BAM by chromosomes.</p>
<p>Using the reference sequence dictionary (<code>*.dict</code>), it also creates some empty BAM files if no sam record was found for a chromosome. A pair of 'mock' SAM-Records can also be added to those empty BAMs to avoid some tools (like samtools) to crash.</p>
<h1>Usage</h1>
<p><code>java -jar splitbam.jar -p OUT/__CHROM__/__CHROM__.bam -R ref.fasta (bam|sam|stdin)</code></p>
<h1>Options</h1>
<ul>
<li>-h help; This screen.</li>
<li>-R (indexed reference file) REQUIRED.</li>
<li>-u (unmapped chromosome name): default:Unmapped</li>
<li>-e | --empty : generate EMPTY bams for chromosome having no read mapped</li>
<li>-m | --mock : if option '-e', add a mock pair of sam records to the empty bam</li>
<li>-p (output file/bam pattern) REQUIRED. MUST contain&nbsp;<strong><code>__CHROM__</code></strong>&nbsp;and end with .bam</li>
<li>-s assume input is sorted.</li>
<li>-x | --index create index.</li>
<li>-t | --tmp (dir) tmp file directory</li>
<li>-G (file) chrom-group file (see below)</li>
</ul><p>Address of the bookmark: <a href="https://code.google.com/archive/p/jvarkit/wikis/SplitBam.wiki" rel="nofollow">https://code.google.com/archive/p/jvarkit/wikis/SplitBam.wiki</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31351/maxbin-software-for-binning-assembled-metagenomic-sequences-based-on-an-expectation-maximization-algorithm</guid>
	<pubDate>Mon, 06 Mar 2017 04:03:38 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31351/maxbin-software-for-binning-assembled-metagenomic-sequences-based-on-an-expectation-maximization-algorithm</link>
	<title><![CDATA[MaxBin: software for binning assembled metagenomic sequences based on an Expectation-Maximization algorithm.]]></title>
	<description><![CDATA[<p><span>MaxBin is software for binning assembled metagenomic sequences based on an Expectation-Maximization algorithm. Users can understand the underlying bins (genomes) of the microbes in their metagenomes by simply providing assembled metagenomic sequences and the reads coverage information or sequencing reads. For users' convenience MaxBin will report genome-related statistics, including estimated completeness, GC content and genome size in the binning summary page.</span><br><br><span>Users can use MEGAN or similar software on MaxBin bins to find the taxonomy of each bin after the binning process is finished.</span></p>
<p>https://academic.oup.com/bioinformatics/article/32/4/605/1744462/MaxBin-2-0-an-automated-binning-algorithm-to<br><br><span>The most recent version of MaxBin is 2.2, which supports the analysis of coassemblies of multiple samples. It is available at this JBEI downloads sites as well as&nbsp;</span><a href="https://sourceforge.net/projects/maxbin/" target="_blank">MaxBin</a><span>&nbsp;and&nbsp;</span><a href="https://sourceforge.net/projects/maxbin2/" target="_blank">MaxBin 2.0</a><span>&nbsp;sourceforge sites.</span></p><p>Address of the bookmark: <a href="http://downloads.jbei.org/data/microbial_communities/MaxBin/MaxBin.html" rel="nofollow">http://downloads.jbei.org/data/microbial_communities/MaxBin/MaxBin.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31382/seqmule-automated-human-exomegenome-variants-detection</guid>
	<pubDate>Tue, 07 Mar 2017 10:12:36 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31382/seqmule-automated-human-exomegenome-variants-detection</link>
	<title><![CDATA[SeqMule: Automated human exome/genome variants detection]]></title>
	<description><![CDATA[<p><span>SeqMule takes single-end or paird-end FASTQ or BAM files, generates a script consisting of more than 10 popular alignment, analysis tools and runs the script line by line. Users can change the pipeline or fine-tune the parameters by modifying its configuration file. SeqMule also has some built-in functions, such as pooling consensus calls from various callers, plotting a Venn diagram showing intersection among different callers, and downloading databases. SeqMule can be used for both Mendelian disease study and cancer genome study.</span></p><p>Address of the bookmark: <a href="http://seqmule.openbioinformatics.org/en/latest/" rel="nofollow">http://seqmule.openbioinformatics.org/en/latest/</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/31881/gbtools-interactive-visualization-of-metagenome-bins-in-r</guid>
	<pubDate>Sun, 26 Mar 2017 15:41:31 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/31881/gbtools-interactive-visualization-of-metagenome-bins-in-r</link>
	<title><![CDATA[gbtools: Interactive Visualization of Metagenome Bins in R]]></title>
	<description><![CDATA[<p><span>We have developed gbtools, a software package that allows users to visualize metagenomic assemblies by plotting coverage (sequencing depth) and GC values of contigs, and also to annotate the plots with taxonomic information. Different sets of annotations, including taxonomic assignments from conserved marker genes or SSU rRNA genes, can be imported simultaneously; users can choose which annotations to plot. Bins can be manually defined from plots, or be imported from third-party binning tools and overlaid onto plots, such that results from different methods can be compared side-by-side. gbtools reports summary statistics of bins including marker gene completeness, and allows the user to add or subtract bins with each other.&nbsp;</span></p>
<p><span>Tool at&nbsp;https://github.com/kbseah/genome-bin-tools</span></p><p>Address of the bookmark: <a href="http://journal.frontiersin.org/article/10.3389/fmicb.2015.01451/full" rel="nofollow">http://journal.frontiersin.org/article/10.3389/fmicb.2015.01451/full</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32709/cabog-celera-assembler-with-best-overlap-graph</guid>
	<pubDate>Mon, 15 May 2017 05:04:39 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32709/cabog-celera-assembler-with-best-overlap-graph</link>
	<title><![CDATA[CABOG: Celera Assembler with Best Overlap Graph]]></title>
	<description><![CDATA[<p>CABOG (Celera Assembler with Best Overlap Graph) is scientific software for&nbsp;<a href="http://bioinformatics.oxfordjournals.org/content/24/24/2818.abstract">DNA research</a>. CABOG has been a critical component of many genome sequencing projects. CABOG operates on small genomes such as bacterial as well as large genomes such as mammalian. CABOG is an extension of the Celera Assembler software that was originally developed at&nbsp;<a href="http://www.celera.com/">Celera</a>&nbsp;for the 2001 publication of the first draft human genome sequence. The software was released to the public domain in 2004. Its open source&nbsp;<a href="http://wgs-assembler.sf.net/">repository</a>&nbsp;on Source Forge is an internet resource for scientists around the world.&nbsp;</p>
<p>CABOG is one of many software programs called genome assemblers. These programs exist to overcome the fundamental limitation of all sequencing machines, namely, that they read out very few DNA letters at a time. These programs reconstruct genomes that are billions of letters long from the hundreds of letters per read that modern sequencers provide. What these programs do is often described as a scaled up version of a family solving a jigsaw puzzle.</p>
<p>The CABOG software was the first to accomplish many scientific goals. It was the first to assemble the genome of a multicellular organism (<em>Drosophila melanogaster</em>, 2000). It was the first to assemble both parental haplotypes of one human genome (J. Craig Venter, 2007). It was the first to assemble environmental sequence from the oceans (Sargasso Sea in 2004 and Global Ocean Sampling in 2007). It was first to combine reads from first-generation Sanger sequencing machines and second-generation pyrosequencing machines (Marine microbes, 2006). Today, CABOG is one of the leading assembly programs for data sets that include paired end data from the Roche 454 line of sequencing machines.</p><p>Address of the bookmark: <a href="http://www.jcvi.org/cms/research/projects/cabog/overview/" rel="nofollow">http://www.jcvi.org/cms/research/projects/cabog/overview/</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/33973/list-of-genome-announcement-notes-and-reporting-journals</guid>
	<pubDate>Wed, 26 Jul 2017 08:01:38 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/33973/list-of-genome-announcement-notes-and-reporting-journals</link>
	<title><![CDATA[List of genome announcement, notes and reporting journals]]></title>
	<description><![CDATA[<p><span>Faced with an increasing number of articles describing DNA data and a need for more appropriate venues to present these data, some publishers and journals have responded by changing the structure and format of genome papers. Specifically, certain journals have started accepting very short manuscripts (500&ndash;1500 words) that present a new chromosome sequence, its GenBank accession number and little else. These pint-sized articles go by various names, such as genome reports, genome announcements, genome notes or genome letters</span><span>, but will be referred to here broadly as genome reports. Their short length and minimal number (or complete absence) of figures, tables and article subheadings are a significant departure from long-form genome papers, which typically span 8&ndash;10 journal pages, contain many supporting items and have formal introduction, methods, results and discussion sections.</span></p><p>Following are the list of journals publishing&nbsp;<span>pint-sized articles go by various names, such as genome reports, genome announcements, genome notes or genome letters</span><span>, but will be referred to here broadly as genome reports.</span></p><p>1. <strong>Genome Announcements</strong>, American Society for Microbiology, Genome announcement, Impact factor 1.3, &nbsp;A 500-word report stating that the genome of a particular organism (prokaryote, eukaryote or virus) has been sequenced and providing a citable record of the corresponding GenBank submission. Must include abstract but no text headings can be used except for &lsquo;Acknowledgments&rsquo; and &lsquo;References&rsquo;. Cannot include figures, tables or supplemental material to present data or analysis.</p><p>Link: https://mra.asm.org/</p><p>2. <strong>Genome Biology and Evolution</strong>, Oxford University Press, Genome report, Impact factor 4.2, Focused 1500-word papers (up to six tables or figures) that publish the main evolutionary message of new genome sequences as they become submitted to GenBank. May also contain specifically focused comparative analyses of previously published genomes that contain a substantial and novel insight of broadest evolutionary significance.</p><p>Link: https://academic.oup.com/gbe</p><p>3. <strong>Journal of Biotechnology</strong>, Elsevier, Genome announcement, Impact factor 2.9, A 500-word report announcing the availability of the completely annotated genome sequence of a biotechnologically relevant organism in the corresponding database (for eukaryotes, advanced draft genomes will also be considered). Articles can contain an Abstract, a brief report on the organism and its biotechnological relevance, a table summarizing the genome features, References and an Acknowledgement. Figures are generally not allowed.</p><p>Link: https://www.journals.elsevier.com/journal-of-biotechnology</p><p>4. <strong>Journal of Genomics</strong>, Ivyspring, Genome note, Impact factor N/A, A 1000-word report (10 reference limit; conclusions not permitted) describing novel data sets from high-throughput analysis of genotypes, phenotypes, gene expression, metabolomes, proteomes or genome assemblies.Standard metrics for data quality and the experimental design must be clearly reported.</p><p>Link: http://www.jgenomics.com/</p><p>5. <strong>Mem&oacute;rias do Instituto</strong>, Oswaldo Cruz Oswaldo Cruz Foundation, Genome announcement and highlight, Impact factor 1.6, Dedicated to publishing new genome information from eukaryote parasites, virus, bacteria and their respective vectors, as well as re-sequencing or comparative genome analyses. Should occupy no more than three printed pages including figures and/or tables.</p><p>Link: http://memorias.ioc.fiocruz.br/</p><p>6. <strong>Molecular Ecology Resources,</strong> Wiley, Genomic resources note, &nbsp;Impact factor 3.7, Short notes on newly assembled and annotated transcriptomes, genome fractions or whole genomes, and/or a library of SNP/SSR markers.Authors submit a short manuscript describing how the resource was developed and where the data can be accessed. Do not appear in journal as individual papers but are instead published as part of a summary article.</p><p>Link: https://onlinelibrary.wiley.com/journal/17550998</p><p>7. <strong>Standards in Genomic Science</strong>, BioMed Central (Springer), Short genome report, Impact factor 3.2,&nbsp;<span>Short (&sim;500-word) article on newly sequenced genome. Article format must follow guidelines and template (available from journal Web site) put forward by the SGS. Any manuscripts not using template or that are missing key figures, tables and/or references (as per the guidelines) will be returned to authors. Rationale of the content model is to provide information that is consistently and uniformly presented for rapid and easy consumption by both human and machine readers.&nbsp;</span></p><p><span>Link: https://standardsingenomics.biomedcentral.com/</span></p><p><span>8. <strong>3biotech</strong>, Springer,&nbsp;<span>Short genome report, Impact factor 1.3,&nbsp;</span><span>Short (&sim;500-word) article on newly sequenced genome. Article format must follow guidelines (available from journal Web site).&nbsp;<span>&nbsp;Genome of a particular organism (prokaryote, eukaryote or virus) has been sequenced and providing a citable record of the corresponding GenBank submission.</span></span></span></p><p><span><span><span>Link: https://link.springer.com/journal/13205</span></span></span></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/35125/eugene-v-koonin-lab</guid>
  <pubDate>Tue, 09 Jan 2018 05:01:15 -0600</pubDate>
  <link></link>
  <title><![CDATA[Eugene V. Koonin Lab]]></title>
  <description><![CDATA[
<p>Interested in understanding the evolution of life. To obtain glimpses of such understanding, we employ existing and new methods of computational biology to perform research in several major areas.</p>

<p>https://www.ncbi.nlm.nih.gov/research/groups/koonin/</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36012/gmol-an-interactive-tool-for-3d-genome-structure-visualization</guid>
	<pubDate>Wed, 21 Mar 2018 12:25:20 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36012/gmol-an-interactive-tool-for-3d-genome-structure-visualization</link>
	<title><![CDATA[GMOL: An Interactive Tool for 3D Genome Structure Visualization]]></title>
	<description><![CDATA[<p><span>GMOL was developed based upon our multi-scale approach that allows a user to scale between six separate levels within the genome. With GMOL, a user can choose any unit at any scale and scale it up or down to visualize its structure and retrieve corresponding genome sequences.</span></p><p>Address of the bookmark: <a href="https://www.nature.com/articles/srep20802" rel="nofollow">https://www.nature.com/articles/srep20802</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36723/hapsembler-an-assembler-for-highly-polymorphic-genomes</guid>
	<pubDate>Tue, 22 May 2018 04:09:53 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36723/hapsembler-an-assembler-for-highly-polymorphic-genomes</link>
	<title><![CDATA[Hapsembler: An Assembler for Highly Polymorphic Genomes]]></title>
	<description><![CDATA[Hapsembler is a haplotype-specific genome assembly toolkit that is designed for genomes that are rich in SNPs and other types of polymorphism. Hapsembler can be used to assemble reads from a variety of platforms including Illumina and Roche/454. 

http://compbio.cs.toronto.edu/hapsembler/<p>Address of the bookmark: <a href="http://compbio.cs.toronto.edu/hapsembler/" rel="nofollow">http://compbio.cs.toronto.edu/hapsembler/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36997/cgview-circular-genome-viewer</guid>
	<pubDate>Wed, 20 Jun 2018 10:15:57 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36997/cgview-circular-genome-viewer</link>
	<title><![CDATA[CGView - Circular Genome Viewer]]></title>
	<description><![CDATA[CGView is a Java package for generating high quality, zoomable maps of circular genomes. Its primary purpose is to serve as a component of sequence annotation pipelines, as a means of generating visual output suitable for the web. Feature information and rendering options are supplied to the program using an XML file, a tab delimited file, or an NCBI ptt file. CGView converts the input into a graphical map (PNG, JPG, or Scalable Vector Graphics format), complete with labels, a title, legends, and footnotes. In addition to the default full view map, the program can generate a series of hyperlinked maps showing expanded views. The linked maps can be explored using any web browser, allowing rapid genome browsing, and facilitating data sharing. The feature labels in maps can be hyperlinked to external resources, allowing CGView maps to be integrated with existing web site content or databases. For examples of the various output types, see the CGView gallery.

http://wishart.biology.ualberta.ca/cgview/gallery.html

http://stothard.afns.ualberta.ca/downloads/CCT/index.html

https://www.gview.ca/wiki/GView/WebHome

https://server.gview.ca/

http://stothard.afns.ualberta.ca/cgview_server/

Paper https://academic.oup.com/bib/advance-article/doi/10.1093/bib/bbx081/4037458<p>Address of the bookmark: <a href="http://wishart.biology.ualberta.ca/cgview/" rel="nofollow">http://wishart.biology.ualberta.ca/cgview/</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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