<![CDATA[BOL: Related items]]> https://bioinformaticsonline.com/related/35257?offset=1290 https://bioinformaticsonline.com/opportunity/view/35026/junior-research-fellow-position-at-translational-health-group-icgeb-new-delhi Tue, 02 Jan 2018 19:47:28 -0600 <![CDATA[Junior Research Fellow position at Translational Health Group, ICGEB, New Delhi]]> One Junior Research Fellow position, in a DBT funded project, is available in the Translational Health Group, ICGEB, New Delhi

Qualifications: MSc (preferably in Biotechnology, Life Sciences or Zoology, Chemistry, Bioinformatics). Candidates with hands-on experience on GC-MS data acquisition and analysis will be given preference. Bioinformatics expertise required.

Fellowship: As per DBT guidelines.

Tenure: The position is purely on temporary basis with an initial tenure of six months and based on satisfactory performance may continue until the completion of the project.

Application Deadline: Applications will be accepted until 07/01/2018

Please send a "TWO PAGE" CV by email to: th.icgeb@gmail.com on or before the date indicated.

]]> https://bioinformaticsonline.com/videolist/watch/12943/a-history-of-bioinformatics-in-the-year-2039 Wed, 23 Jul 2014 06:37:51 -0500 https://bioinformaticsonline.com/videolist/watch/12943/a-history-of-bioinformatics-in-the-year-2039 <![CDATA[A History of Bioinformatics (in the Year 2039)]]>

C. Titus Brown http://video.open-bio.org/video/1/a-history-of-bioinformatics-in-the-year-2039

]]> https://bioinformaticsonline.com/file/view/1970/indias-own-first-drug-from-biocon Sun, 11 Aug 2013 16:05:39 -0500 https://bioinformaticsonline.com/file/view/1970/indias-own-first-drug-from-biocon <![CDATA[India's own first drug - from Biocon.]]> Psoriasis is immune-mediated disease that effects the skin. the Disease on an average affects about 10-20 million Indians and it attacks the immune system of human beings. In generally occurs, when the immune system mistakes a normal skin cell for a pathogen, and sends out faulty signals that cause overproduction of new skin cells. More at >>

Biocon, India's largest publicly-held biotechnology firm, launched its second novel 'lab-to-market' molecule, Alzumab, to treat chronic plaque psoriasis at a cost 50 per cent lower than the existing one.

Biocon is bringing Alzumab (a biologic) in the form of a vial after working on it for nearly a decade. The work had initially started in a joint effort with the Center of Molecular Immunology, Havana, but Biocon took control of the programme soon after and also bought out its partner a few years ago. Biocon tell to the media that genotypic played a critical role in functional studies and clinical trial Genomics.

The Biocon drug, at around ₹ 7,500 a vial, will cost half as much as the currently available drugs - from Pfizer and J&J - to treat psoriasis, a skin disease that causes rough red areas where the skin comes off in small pieces. A patient is usually prescribed to consume more than 40 vials in a 24-week course.

]]> Jitendra Narayan https://bioinformaticsonline.com/news/view/11144/scientists-map-17294-proteins-produced-in-human-body Thu, 29 May 2014 01:57:55 -0500 https://bioinformaticsonline.com/news/view/11144/scientists-map-17294-proteins-produced-in-human-body <![CDATA[Scientists map 17,294 proteins produced in human body]]> Indian scientists missed the genomic profiling bus, but they've more than made up for it by creating the first human proteome map which is an extension of the genomic study. Till now, here is no direct equivalent for the human proteome. But recently two groups present mass spectrometry-based analysis of human tissues, body fluids and cells mapping the large majority of the human proteome.

The Indian scientists working in Bangalore, along with their American counterparts, have mapped more than 17,000 proteins in 30 organs of the human body. Just like the human genome was sequenced around the turn of the millennium, this is an equivalent mapping of the human proteome.

The researcher estimated there are around 20,500 proteins in the human body. These scientists have profiled around 17,294, which account for around 84% of the total proteins. Apart from this, the team also traced around 2,500 of 3,000 proteins that had been categorised as "missing proteins".

The work, done by group of Indian scientists, and Johns Hopkins University, published in the renowned journal Nature ( http://www.nature.com/nature/journal/v509/n7502/full/nature13302.html ). Of the 72 people who worked on the project, 46 are Indians.

Reference:

http://www.nature.com/nature/journal/v509/n7502/full/nature13302.html

http://www.proteinatlas.org/ -The antibody-based Human Protein Atlas programme

http://www.humanproteomemap.org/ -Proteogenomic analysis by identifying translated proteins from annotated pseudogenes, non-coding RNAs and untranslated regions.

https://www.proteomicsdb.org/ -Assembled protein evidence for 18,097 genes in ProteomicsDB

 

]]> Jit https://bioinformaticsonline.com/researchlabs/view/4546/sowdhamini-lab Sun, 15 Sep 2013 09:19:12 -0500 <![CDATA[SOWDHAMINI Lab]]> Genome sequencing projects have enormous potential for benefiting human endeavors. However, just as acquiring a language's vocabulary does not enable one to speak it, databases that list the amino acid composition of proteins do not directly tell us much about these proteins' higher-level structure and function. The most productive way to indirectly exploit these databases has been to start with the small number of proteins that are fully-characterised and to assume that other "similar" proteins will have a related structure and function. Proteins with very similar amino acid sequence are "no-brainers", but the real test, which our group largely focuses on, is to detect the "essential" similarity in proteins whose non-critical sections have experienced random rearrangements during evolution. In such cases functionally similar proteins may have less than 25% sequence overlap.

More @ http://www.ncbs.res.in/sowdhamini/groups_sowdhamini.htm

]]> https://bioinformaticsonline.com/videolist/watch/11249/how-to-sequence-the-human-genome-mark-j-kiel Fri, 30 May 2014 13:24:11 -0500 https://bioinformaticsonline.com/videolist/watch/11249/how-to-sequence-the-human-genome-mark-j-kiel <![CDATA[How to sequence the human genome - Mark J. Kiel]]> View full lesson: http://ed.ted.com/lessons/how-to-sequence-the-human-genome-mark-j-kiel Your genome, every human's genome, consists of a unique DNA sequence of A's, T's, C's and G's that tell your cells how to operate. Thanks to technological advances, scientists are now able to know the sequence of letters that makes up an individual genome relatively quickly and inexpensively. Mark J. Kiel takes an in-depth look at the science behind the sequence. Lesson by Mark J. Kiel, animation by Marc Christoforidis.]]> https://bioinformaticsonline.com/videolist/watch/11354/genomics-and-personalized-medicine Sun, 01 Jun 2014 23:38:42 -0500 https://bioinformaticsonline.com/videolist/watch/11354/genomics-and-personalized-medicine <![CDATA[Genomics and Personalized Medicine]]> (October 20, 2009) Michael Snyder, Professor of Genetics and Chair of the Department of Genetics at Stanford, discusses advances in gene sequencing, the impact of genomics on medicine, the potential for personalized medicine. and efforts at Stanford to further study these issues. Stanford Mini Med School is a series arranged and directed by Stanford's School of Medicine, and presented by the Stanford Continuing Studies program. Featuring more than thirty distinguished, faculty, scientists and physicians from Stanford's medical school, the series offers students a dynamic introduction to the world of human biology, health and disease, and the groundbreaking changes taking place in medical research and health care. Stanford University http://www.stanford.edu Stanford University School of Medicine http://med.stanford.edu Stanford Continuing Studies http://continuingstudies.stanford.edu Stanford University Channel on YouTube: http://www.youtube.com/stanford]]> https://bioinformaticsonline.com/blog/view/41455/coronavirus-covid-%E2%80%9019-testing-sites-in-india Mon, 16 Mar 2020 16:13:41 -0500 https://bioinformaticsonline.com/blog/view/41455/coronavirus-covid-%E2%80%9019-testing-sites-in-india <![CDATA[Coronavirus COVID ‐19 Testing Sites In India]]> COVID-19 is a new illness that can affect your lungs and airways. It's caused by a virus called coronavirus.

Stay at home if you have coronavirus symptoms

Stay at home if you have either:

  • a high temperature – you feel hot to touch on your chest or back
  • a new, continuous cough – this means you've started coughing repeatedly

DO NOT TAKE

Ibrufen

https://amp.theguardian.com/world/2020/mar/14/anti-inflammatory-drugs-may-aggravate-coronavirus-infection

How to avoid catching and spreading coronavirus (social distancing)

Everyone should do what they can to stop coronavirus spreading.

It is particularly important for people who:

  • are 70 or over
  • have a long-term condition
  • are pregnant
  • have a weakened immune system

image

Below are the 52 Coronavirus COVID-19 Testing sites/locations in India.

State: Andhra Pradesh       

  1. Sri Venkateswara Institute of Medical Sciences, Tirupati
  2. Andhra Medical College, Visakhapatnam, Andhra Pradesh
  3. GMC, Anantapur, AP

State: Andaman & Nicobar islands

  1. Regional Medical Research Centre, Port Blair, Andaman, and Nicobar

State: Assam

  1. Gauhati Medical College, Guwahati
  2.  Regional Medical Research Center, Dibrugarh

State: Bihar

  1. Rajendra Memorial Research Institute of Medical Sciences, Patna

State: Chandigarh

  1. Post Graduate Institute of Medical Education & Research, Chandigarh

State: Chhattisgarh

  1. All India Institute Medical Sciences, Raipur

Union Territory: Delhi-NCT 

  1. All India Institute Medical Sciences, Delhi
  2. National Centre for Disease Control, Delhi

State: Gujarat

  1. BJ Medical College, Ahmedabad
  2. M.P.Shah Government Medical College, Jamnagar

State: Haryana

  1. Pt. B.D. Sharma Post Graduate Inst. of Med. Sciences, Rohtak, Haryana
  2. BPS Govt Medical College, Sonipat

State: Himachal Pradesh

  1. Indira Gandhi Medical College, Shimla, Himachal Pradesh
  2. Dr.Rajendra Prasad Govt. Med. College, Kangra, Tanda, HP

Union Territory: Jammu and Kashmir

  1. Sher‐e‐ Kashmir Institute of Medical Sciences, Srinagar
  2. Government Medical College, Jammu

State: Jharkhand

  1. MGM Medical College, Jamshedpur

State: Karnataka

  1. Bangalore Medical College & Research Institute, Bangalore
  2. National Institute of Virology Field Unit Bangalore
  3. Mysore Medical College & Research Institute, Mysore
  4. Hassan Inst. of Med. Sciences, Hassan, Karnataka
  5. Shimoga Inst. of Med. Sciences, Shivamogga, Karnataka

State: Kerala

  1. National Institute of Virology Field Unit, Kerala
  2. Govt. Medical College, Thiruvananthapuram, Kerala
  3. Govt. Medical College, Kozhikode, Kerala

State: Madhya Pradesh

  1. All India Institute Medical Sciences, Bhopal
  2. National Institute of Research in Tribal Health (NIRTH), Jabalpur

State: Meghalaya

  1. NEIGRI of Health and Medical Sciences, Shillong, Meghalaya

State: Maharashtra

  1. Indira Gandhi Government Medical College, Nagpur
  2. Kasturba Hospital for Infectious Diseases, Mumbai

State: Manipur

  1. J N Inst. of Med. Sciences Hospital, Imphal‐East, Manipur

State: Odisha

  1. Regional Medical Research Center, Bhubaneswar

Union Territory: Puducherry

  1. Jawaharlal Institute of Postgraduate Medical Education & Research, Puducherry

State: Punjab

  1. Government Medical College, Patiala, Punjab
  2. Government Medical College, Amritsar

State: Rajasthan

  1. Sawai Man Singh, Jaipur
  2. Dr. S.N Medical College, Jodhpur
  3. Jhalawar Medical College, Jhalawar, Rajasthan
  4. SP Med. College, Bikaner, Rajasthan

State: Tamil Nadu

  1. King’s Institute of Preventive Medicine & Research, Chennai
  2. Government Medical College, Theni

State: Tripura

  1. Government Medical College, Agartala

State: Telangana

  1. Gandhi Medical College, Secunderabad

State: Uttar Pradesh

  1. King’s George Medical University, Lucknow
  2. Institute of Medical Sciences, Banaras, Hindu University, Varanasi
  3. Jawaharlal Nehru Medical College, Aligarh

State: Uttarakhand

  1. Government Medical College, Haldwani

State: West Bengal

  1. National Institute of Cholera and Enteric Diseases, Kolkata
  2. IPGMER, Kolkata
]]> Neel https://bioinformaticsonline.com/pages/view/11735/search-shell-command-history Thu, 12 Jun 2014 17:43:34 -0500 https://bioinformaticsonline.com/pages/view/11735/search-shell-command-history <![CDATA[Search Shell Command History]]> We use couple of hundreads of command in daily basis. Most of them are actually repeated several time. The question remain open how do I search old command history under bash shell and modify or reuse it?

Now a days almost all modern shell allows you to search command history if enabled by user. Use history command to display the history list with line numbers. Lines listed with with a * have been modified by user.


Shell history search command

Type history at a shell prompt:
$ history

It will display the list of all used commandline history with an serial number.

To search particular command, enter:
$ history | grep command-name
$ history | egrep -i 'scp|ssh|ftp'
Emacs Line-Edit Mode Command History Searching

To get previous command containing string, hit [CTRL]+[r] followed by search string:

(reverse-i-search):

To get previous command, hit [CTRL]+[p]. You can also use up arrow key.

CTRL-p

To get next command, hit [CTRL]+[n]. You can also use down arrow key.

CTRL-n

fc command

Apart from hostory command there are fc command to extract the command from history. The fc stands for either "find command" or "fix command.

For example list last 10 command, enter:
$ fc -l 10
To list commands 130 through 150, enter:
$ fc -l 130 150
To list all commands since the last command beginning with ssh, enter:
$ fc -l ssh
You can edit commands 1 through 5 using vi text editor, enter:
$ fc -e vi 1 5

Delete command history

The -c option causes the history list to be cleared by deleting all of the entries:
$ history -c

]]> Rahul Nayak https://bioinformaticsonline.com/researchlabs/view/42958/claus-peter-stelzer-lab Mon, 15 Mar 2021 15:24:41 -0500 <![CDATA[Claus-Peter Stelzer Lab]]> Interested in various topics at the intersection of ecology and evolution. In my research I use rotifers as model organisms for experimental studies at the individual and population level. Rotifers are ideally suited for this, because populations of thousands can be kept in small containers in the lab, while single individuals can still be handled conveniently.

More at https://www.uibk.ac.at/limno/personnel/stelzer/index.html.en#research

]]>