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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/35525?offset=1210</link>
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	<description><![CDATA[]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/11354/genomics-and-personalized-medicine</guid>
	<pubDate>Sun, 01 Jun 2014 23:38:42 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/11354/genomics-and-personalized-medicine</link>
	<title><![CDATA[Genomics and Personalized Medicine]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/pgHAXCMMcro" frameborder="0" allowfullscreen></iframe>(October 20, 2009) Michael Snyder, Professor of Genetics and Chair of the Department of Genetics at Stanford, discusses advances in gene sequencing, the impact of genomics on medicine, the potential for personalized medicine. and efforts at Stanford to further study these issues.

Stanford Mini Med School is a series arranged and directed by Stanford's School of Medicine, and presented by the Stanford Continuing Studies program. Featuring more than thirty distinguished, faculty, scientists and physicians from Stanford's medical school, the series offers students a dynamic introduction to the world of human biology, health and disease, and the groundbreaking changes taking place in medical research and health care.

Stanford University
http://www.stanford.edu

Stanford University School of Medicine
http://med.stanford.edu

Stanford Continuing Studies
http://continuingstudies.stanford.edu

Stanford University Channel on YouTube:
http://www.youtube.com/stanford]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/35559/computational-resources-for-te-discovery-and-te-detection</guid>
	<pubDate>Mon, 12 Feb 2018 10:29:18 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/35559/computational-resources-for-te-discovery-and-te-detection</link>
	<title><![CDATA[Computational resources for TE discovery and TE detection]]></title>
	<description><![CDATA[<p><span>Transposable Elements (TEs) to genome structure and evolution as well as their impact on genome sequencing, assembly, annotation and alignment has generated increasing interest in developing new methods for their computational analysis. </span></p><p><span>Following are the list of r</span><span>esource and location for TE discovery and TE detection:</span></p><p>BLASTER suite&nbsp;http://urgi.versailles.inra.fr/development/blaster/&nbsp;</p><p>Censor&nbsp;http://www.girinst.org/censor/download.php&nbsp;</p><p>find_ltr&nbsp;http://darwin.informatics.indiana.edu/cgi-bin/evolution/ltr.pl&nbsp;</p><p>FINDMITE http://jaketu.biochem.vt.edu/dl_software.htm </p><p>HMMER http://hmmer.janelia.org/ </p><p>LTR_FINDER http://tlife.fudan.edu.cn/ltr_finder/ </p><p>LTR_STRUC http://www.genetics.uga.edu/retrolab/data/LTR_Struc.html </p><p>LTR_MINER http://genomebiology.com/2004/5/10/R79/suppl/s7 </p><p>LTR_par http://www.eecs.wsu.edu/~ananth/software.htm </p><p>MAK http://wesslercluster.plantbio.uga.edu/mak06.html </p><p>MaskerAid http://blast.wustl.edu/maskeraid/ </p><p>mer-engine http://mer-engine.cshl.edu/mer-home.php </p><p>mreps http://bioinfo.lifl.fr/mreps/ </p><p>PILER http://www.drive5.com/piler/ </p><p>PLOTREP http://repeats.abc.hu/cgi-bin/plotrep.pl </p><p>RepBase http://www.girinst.org/ </p><p>RepeatFinder http://cbcb.umd.edu/software/RepeatFinder/ </p><p>RepeatGluer http://nbcr.sdsc.edu/euler/intro_tmp.htm </p><p>RepeatMasker http://www.repeatmasker.org/ </p><p>RepeatRunner http://www.yandell-lab.org/repeat_runner/index.html </p><p>RepeatScout http://repeatscout.bioprojects.org/ </p><p>repeat-match http://mummer.sourceforge.net/ </p><p>REPuter http://www.genomes.de/ </p><p>RetroMap http://www.burchsite.com/bioi/RetroMapHome.html </p><p>SMaRTFinder http://bioinf.dimi.uniud.it/software/software/smartfinder </p><p>Tandem Repeats Finder http://tandem.bu.edu/trf/trf.html </p><p>Transposon Cluster Finder http://www.mssm.edu/labs/warbup01/paper/files.html </p><p>TE nest http://www.plantgdb.org/prj/TE_nest/TE_nest.html </p><p>TRANSPO http://alggen.lsi.upc.es/recerca/search/transpo/transpo.html </p><p>TSDfinder http://www.ncbi.nlm.nih.gov/CBBresearch/Landsman/TSDfinder/ </p><p>Tu Lab TE tools http://jaketu.biochem.vt.edu/dl_software.htm </p><p>WU-BLAST http://blast.wustl.edu</p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/35267/a-computational-postdoc-position-and-a-bioinformatician-position</guid>
  <pubDate>Thu, 18 Jan 2018 16:29:42 -0600</pubDate>
  <link></link>
  <title><![CDATA[A computational postdoc position and a bioinformatician position]]></title>
  <description><![CDATA[
<p>A computational postdoc position and a bioinformatician position are available in Alessandro Romanel's Lab recently established at the Centre for Integrative Biology (CIBIO) in Trento, Italy. The positions are in the context of an AIRC grant and are immediately available.<br /> <br />Successful candidates will be involved in the design and implementation of strategies to study the role of inherited polymorphisms in combination with timedependent variables and somatic events on cancer genesis, progression and resistance.<br />The ideal postdoc candidate will have a PhD in Computer Science, Bioinformatics, Computational Biology or equivalent, experience in the analysis of next generation sequencing and high-density array data from human cells, strong analytical and quantitative background and programming skills. Background in cancer genomics is recommended.<br />The ideal bioinformatician candidate will have a four or five years degree in Computer Science, Bioinformatics or equivalent, experience in the management of large datasets, implementation of processing pipelines and strong programming skills. Background in biology/genomics is a plus.<br />Highly motivated individuals are invited to send a detailed CV, a cover letter describing research interests and experience, and contact information for two references to Alessandro Romanel (alessandro.romanel@unitn.it).</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42201/rosettaantibodydesign-rabd-a-general-framework-for-computational-antibody-design</guid>
	<pubDate>Sun, 20 Sep 2020 06:03:42 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42201/rosettaantibodydesign-rabd-a-general-framework-for-computational-antibody-design</link>
	<title><![CDATA[RosettaAntibodyDesign (RAbD): A general framework for computational antibody design]]></title>
	<description><![CDATA[<p><strong>RosettaAntibodyDesign (RAbD)</strong>&nbsp;is a generalized framework for the design of antibodies, in which a user can easily tailor the run to their project needs.&nbsp;<strong>The algorithm is meant to sample the diverse sequence, structure, and binding space of an antibody-antigen complex.</strong>&nbsp;It can be used for a multitude of project types, from denovo design to redesigns that improve binding affinity, optimize stability, or manipulate function.</p>
<p>The framework is based on rigorous bioinformatic analysis and rooted very much on our&nbsp;<a href="https://www.ncbi.nlm.nih.gov/pubmed/21035459">recent clustering</a>&nbsp;of antibody CDR regions. It uses the&nbsp;<strong>North/Dunbrack CDR definition</strong>&nbsp;as outlined in the North/Dunbrack clustering paper.</p>
<p>More at</p>
<p>https://www.rosettacommons.org/docs/latest/application_documentation/antibody/RosettaAntibodyDesign</p>
<p>https://bio-jade.readthedocs.io/en/latest/installation.html</p><p>Address of the bookmark: <a href="https://www.rosettacommons.org/docs/latest/application_documentation/antibody/RosettaAntibodyDesign" rel="nofollow">https://www.rosettacommons.org/docs/latest/application_documentation/antibody/RosettaAntibodyDesign</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/11609/bioinformatician%E2%80%99s-pocket-reference</guid>
	<pubDate>Sun, 08 Jun 2014 09:56:58 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/11609/bioinformatician%E2%80%99s-pocket-reference</link>
	<title><![CDATA[Bioinformatician’s Pocket Reference !!]]></title>
	<description><![CDATA[<p><span>It is amusing how brain of bioinformaticians work! Learning a new programming language for days feels so much of fun that making 5 minute discussion with neighbours (unless under special circumstances!) in our own mother-tongue. Today every bioinformatician keeps more than few languages and core IT toolkits on their plate. It has become mandatory to be able to mould different code snippets to build our own custom workflows, and thus keeping syntax at our fingertips has become essential.Although Google is best way to get syntax problem solved, it is not a bad idea to keep reference sheets is our smartphones or stick out some printed sheets on the back of your door, in the old fashion way!!</span></p><p>Address of the bookmark: <a href="http://infoplatter.wordpress.com/2014/04/06/bioinformaticians-pocket-reference/" rel="nofollow">http://infoplatter.wordpress.com/2014/04/06/bioinformaticians-pocket-reference/</a></p>]]></description>
	<dc:creator>RAJESH DETROJA</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/34864/installing-perl-environment-on-linux</guid>
	<pubDate>Tue, 26 Dec 2017 21:21:50 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/34864/installing-perl-environment-on-linux</link>
	<title><![CDATA[Installing Perl environment on Linux]]></title>
	<description><![CDATA[<p>By using&nbsp;<code>plenv</code>, you can easily install and switch among different version of Perl. This will be installed under your home directory in<code>~/.plenv</code>.</p><h4>Install latest Perl (with supporting multithreading) and CPANMinus.</h4><pre><code> $ cd
 $ git clone git://github.com/tokuhirom/plenv.git ~/.plenv
 $ git clone git://github.com/tokuhirom/Perl-Build.git ~/.plenv/plugins/perl-build/
 $ echo 'export PATH="$HOME/.plenv/bin:$PATH"' &gt;&gt; ~/.bashrc
 $ echo 'eval "$(plenv init -)"' &gt;&gt; ~/.bashrc
 $ source ~/.bashrc
 $ plenv install 5.18.1 -Dusethreads
 $ plenv rehash
 $ plenv global 5.18.1
 $ plenv install-cpanm
</code></pre><ul>
<li><code>git</code>&nbsp;is a distributed revision control and source code management software which can help you to download files from GitHub server.</li>
<li><code>echo</code>&nbsp;means "print".</li>
<li><code>&gt;&gt;</code>&nbsp;means adding the output into the end of the file, while&nbsp;<code>&gt;</code>&nbsp;means adding the output by overwriting the whole file. Please use<code>&gt;</code>&nbsp;with additional cares.</li>
<li>In Linux system, there are two types of outputs when you execute a command. One is called standard output (or sometimes STDOUT for short), and the other is a standard error (STDERR).&nbsp;<code>1&gt;</code>&nbsp;is for STDOUT only,&nbsp;<code>2&gt;</code>&nbsp;is for STDERR only, and&nbsp;<code>&amp;&gt;</code>means for both. In default&nbsp;<code>&gt;</code>&nbsp;is the same to&nbsp;<code>1&gt;</code>.</li>
<li><code>exec</code>&nbsp;is execution.</li>
<li>Remember to install Perl in supporting multithreading (with option&nbsp;<code>-Dusethreads</code>), which is important for many NGS analysis packages (e.g. Trinity). In this setting, you can use multiple CPU for Perl software.</li>
<li>Install the CPAN (Comprehensive Perl Archive Network) manager software, CPANMinus, by&nbsp;<code>install-cpanm</code>.</li>
</ul><p>You can use&nbsp;<code>plenv global</code>&nbsp;and&nbsp;<code>plenv local</code>&nbsp;to change the different version of Perl to fulfil different needs of your Perl software.</p><p>For example, if the&nbsp;specific version of Perl is not compatible with your script, you can switch to the different version by:</p><pre><code> $ plenv local 
</code></pre><ul>
<li>It is similar to set the local version of your script language when you use&nbsp;<code>pyenv</code>&nbsp;and&nbsp;<code>rbenv</code>&nbsp;as the following.</li>
</ul><p>Put the following path into&nbsp;<code>~/.bashrc file</code>.</p><pre><code>export PERL5LIB="$HOME/.plenv/build/perl-5.18.1/lib"
</code></pre><h4>Install BioPerl and PerlIO::gzip</h4><p>CPANMinus is a very good Perl module manager, use&nbsp;<code>cpanm</code>&nbsp;to install BioPerl can save you a lot of time. Here are some useful modules:</p><pre><code>$ cpanm Bio::Perl
$ cpanm Bio::SearchIO
$ cpanm PerlIO::gzip<br /></code></pre><p><span>For more information, please visit:&nbsp;</span><a href="https://github.com/tokuhirom/plenv">https://github.com/tokuhirom/plenv</a></p><pre><code>&nbsp;</code></pre>]]></description>
	<dc:creator>biogeek</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/12218/assistant-professor-in-medical-bioinformatics</guid>
  <pubDate>Tue, 24 Jun 2014 01:46:36 -0500</pubDate>
  <link></link>
  <title><![CDATA[Assistant Professor in Medical Bioinformatics]]></title>
  <description><![CDATA[
<p>Advt. No : ME-I/A-IV/03/14<br />No.of Posts:01 (SC)<br />Pay Scale:<br />Pay Band of Rs.15600-39100 + Rs.6000/- GP +NPA @ 25% of Basic Pay +Learning Resource Allowance @ Rs.20,000/-P.A.+ Conveyance Allowance @ Rs. 1650/-P.M.+ Academic Allowance @ Rs.2500/- P.M. and other admissible allowances.<br />Qualifications:<br />Area of Specialization:-<br />Bioinformatics/Computational/Biology/Genomics/ Proteomics/ Structural Biology<br />1. Postgraduate qualification, e.g. Master’s Degree in Biotechnology/Bioinformatics/ Biophysics.<br />2. A Doctorate Degree of recognized University/Institute in a basic or allied Medical Science subject e.g. Medical Biotechnology/Biophysics. Bioinformatics/X-ray Crystallography/<br />Immunology/Structural Biology etc<br />Experience:<br />1.Minimum three years teaching and/or research experience in a recognized medical/research Institution in an allied medical subject after obtaining doctorate degree and preferably in Medical<br />Molecular Biology/ Biophysics/Structural Biology/Genomics and Clinical Proteomics/Computational Biology.<br />2. Minimum two publication with atleast one in international journal and atleast one as first author<br />Desirable:-<br />Consistently excellent scholastic/academic record, demonstrated ability to write grant proposal/(s) successfully, Post Doctoral training in a frontier area of medical Bioinformatics Research and of direct relevance to clinical diagnosis or patient care (preferably from a recognized top-ranking medical institution abroad)<br />Send your applications to O/O, Deputy Registrar, Recruitment &amp; Establishment Cell, University of Health Sciences, Rohtak by 08.7.2014<br />For more details,please visit website: http://pgimsrohtak.nic.in/2014%20AP%20Advt.pdf<br />Last Apply Date: 08 Jul 2014</p>
]]></description>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/41043/postdoctoral-scientist-genome-analytics-genome-bioinformatics-mf</guid>
  <pubDate>Sun, 16 Feb 2020 02:57:40 -0600</pubDate>
  <link></link>
  <title><![CDATA[Postdoctoral scientist genome analytics/ genome bioinformatics (m/f/*)]]></title>
  <description><![CDATA[
<p>https://www.uksh.de/jobs/Stellenangebote-nr-20190570-p-8.html<br />Your profile:<br />Degree in bioinformatics, biostatistics, or equivalent<br />Experience in the processing and analysis of large-scale genomics data using compute clusters / high-performance computing<br />Strong competence in working in Unix/Linux environments (shell)<br />Strong programming skills (in particular: Python, R, Perl)<br />Experience with using git and snakemake<br />Fluent English language skills, both spoken and written<br />Strong communication skills and motivation to work in a young, interdisciplinary, dynamic team</p>

<p>Additional Information:</p>

<p>If you have any questions about scientific aspects of this position, please contact Prof. Lars Bertram, head of LIGA (lars.bertram@uni-luebeck.de).</p>

<p>Please contact Ms. Anna Wolbert for further questions about administrative details (recruiting@uksh.de).</p>

<p>Weitere Informationen erhalten Sie auch unter www.uksh.de/karriere.</p>

<p>Wir freuen uns auf Ihre Bewerbung bis zum 15.03.2020 unter Angabe unserer Ausschreibungsnummer 20190570.119.CL.</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/12582/postdoc-position-at-centre-mediterraneen-de-medecine-moleculaire</guid>
  <pubDate>Sun, 06 Jul 2014 11:23:06 -0500</pubDate>
  <link></link>
  <title><![CDATA[Postdoc position at Centre Méditerranéen de Médecine Moléculaire]]></title>
  <description><![CDATA[
<p>The research group of Dr. Michele Trabucchi at the Centre Méditerranéen de Médecine Moléculaire (C3M) at INSERM U1065 (University of Nice Sophia-Antipolis, France) is seeking candidates for a Postdoctoral fellow position to start on October 2014 for 3 years funded by FRM (Fondation pour la Recherche Médicale).<br />The broad interest of the lab is in understanding the expression control and function of small RNAs in activated myeloid cells (visit our webpage to check research interests and publications of the group : http://www.unice.fr/c3m/EN/Equipe10.html ). </p>

<p>The work will focus on the functional studies of small RNAs by using next-generation sequencing approaches.<br /> <br />Candidates should hold a Ph.D. degree and have strong background in bioinformatics.<br />The University of Nice Sophia-Antipolis provides a wide range of facilities and training essential for biomedical research.<br />Interested applicants should send a PDF with a cover letter stating research interests and qualifications, an updated CV, a summary of previous research experience and contact information for two references to Michele Trabucchi ( mtrabucchi@unice.fr )</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/42003/perl-one-liner-for-beginners</guid>
	<pubDate>Fri, 24 Jul 2020 05:58:28 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/42003/perl-one-liner-for-beginners</link>
	<title><![CDATA[Perl one-liner for beginners !]]></title>
	<description><![CDATA[<p>I often use the following arguments to perl:</p><ul>
<li>-e Makes the line of code be executed instead of a script</li>
<li>-n Forces your line to be called in a loop. Allows you to take lines from the diamond operator (or stdin)</li>
<li>-p Forces your line to be called in a loop. Prints $_ at the end</li>
</ul><p>&nbsp;</p><ul>
<li>This counts the number of quotation marks in each line and prints it
<div>
<blockquote>
<div>perl -ne&nbsp;'$cnt = tr/"//;print "$cnt\n"'&nbsp;inputFileName.txt</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>Adds string to each line, followed by tab
<div>
<blockquote>
<div>perl -pe&nbsp;'s/(.*)/string\t$1/'&nbsp;inFile &gt; outFile</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>Append a new line to each line
<div>
<blockquote>
<div>perl -pe&nbsp;'s//\n/'&nbsp;all.sent.classOnly &gt; all.sent.classOnly.sep</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>Replace all occurrences of pattern1 (e.g. [0-9]) with pattern2
<div>
<blockquote>
<div>perl -p -i.bak -w -e&nbsp;'s/pattern1/pattern2/g'&nbsp;inputFile</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>Go through file and only print words that do not have any uppercase letters.
<div>
<blockquote>
<div>perl -ne&nbsp;'print unless m/[A-Z]/'&nbsp;allWords.txt &gt; allWordsOnlyLowercase.txt</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>Go through file, split line at each space and print words one per line.
<div>
<blockquote>
<div>perl -ne&nbsp;'print join("\n", split(/ /,$_));print("\n")'&nbsp;someText.txt &gt; wordsPerLine.txt</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>or in other words, delete every character that is not a letter, white space or line end (replace with nothing)
<div>
<blockquote>
<div>perl -pne&nbsp;'s/[^a-zA-Z\s]*//g'&nbsp;text_withSpecial.txt &gt; text_lettersOnly.txt</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>
<div>
<div>perl -pne&nbsp;'tr/[A-Z]/[a-z]/'&nbsp;textWithUpperCase.txt &gt; textwithoutuppercase.txt;</div>
</div>
</li>
</ul><ul>
<li>Print only the second column of the data when using tabular as a separator
<div>
<blockquote>
<div>perl -ne&nbsp;'@F = split("\t", $_); print "$F[1]";'&nbsp;columnFileWithTabs.txt &gt; justSecondColumn.txt</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>
<div>One-Liner: Sort lines by their length
<blockquote>
<div>perl -e&nbsp;'print sort {length $a &lt;=&gt; length $b} &lt;&gt;'&nbsp;textFile</div>
</blockquote>
</div>
</li>
</ul><ul>
<li>One-Liner: Print second column, unless it contains a number
<blockquote>
<div>perl"&gt;perl -lane&nbsp;'print $F[1] unless $F[1] =~ m/[0-9]/'&nbsp;wordCounts.txt</div>
</blockquote>
</li>
</ul>]]></description>
	<dc:creator>BioStar</dc:creator>
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