<![CDATA[BOL: Related items]]> https://bioinformaticsonline.com/related/35798?offset=10 https://bioinformaticsonline.com/pages/view/42810/bioinformatics-in-africa-part3-mali Sat, 06 Feb 2021 13:28:44 -0600 https://bioinformaticsonline.com/pages/view/42810/bioinformatics-in-africa-part3-mali <![CDATA[Bioinformatics in Africa: Part3 - Mali]]> International Center for Excellence in Research (ICER):

The ICER is a research center composed of the following three programs: 1. The Malaria Research and Training Center ­ Parasitology Group,  2. The Malaria Research and Training Center ­ Entomology Group  3. The SEREFO Group.

The first two programs develop biomedical researches in malaria, Filariasis and Leishmaniasis. The  third program develops biomedical researches in tuberculosis and HIV.

Bioinformatics was introduced recently to the ICER and is constantly growing. The ICER has one  team, headed by Sidy SOUMARE, which supports the three programmes in all their needs in  informatics and bioinformatics. This team can beneficiate from some computational facilities (4  blast servers, 15 other servers and around 200 terminals), but the ICER staff needs some training in  order to be able to administrate these facilities.

Research Interest and Activities: The following are the present areas of research interest: 1. Functional genomics 2. Analysis of microarray data 3. Interaction between the vector and the parasite.

]]> BioStar https://bioinformaticsonline.com/opportunity/view/43292/bioinformatics-scientist-production-bioinformatics-south-san-francisco-ca Thu, 19 Aug 2021 08:45:24 -0500 <![CDATA[Bioinformatics Scientist, Production Bioinformatics @ South San Francisco, CA]]> wist is looking for a Bioinformatics Scientist to join our Production Bioinformatics Team. You will work alongside research scientists, software engineers and data scientists to further deliver on our mission to expand access to best-in-class synthetic biology and next-generation sequencing applications. You will be developing and engineering tools to better evaluate and build hardened, production quality pipelines, optimize data quality, and automate lab and bioinformatics processes. Our ideal candidate is an organized problem solver with a background in developing and building novel production-quality bioinformatics tools and packages. Equally excellent communication skills and a proven ability to work independently are required.

More at https://boards.greenhouse.io/twistbioscience/jobs/3135495?gh_src=9ecc0b941us

]]> https://bioinformaticsonline.com/videolist/watch/14218/pimp-your-brain-bioinformatics Wed, 20 Aug 2014 22:09:21 -0500 https://bioinformaticsonline.com/videolist/watch/14218/pimp-your-brain-bioinformatics <![CDATA[Pimp your brain: Bioinformatics]]> Jan Lisec from the Max Planck Institute of Molecular Plant Physiology explains, in this "pimp your brain" episode, what bioinformatics is and why bioinformatics is so important and indispensable for biological research. In the video serial "Pimp your brain" scientists from the Max Planck Institute of Molecular Plant Physiology describe their research. More videos from the 'Pimp your brain' serial are available on www.youtube.com/playlist?list=PL-l9VItC9Gn2Ur2Xj6PTOAkjLUlVPbIOO More videos are available on www.mpimp-golm.mpg.de]]> https://bioinformaticsonline.com/bookmarks/view/27463/bpipe-a-tool-for-running-and-managing-bioinformatics-pipelines Sat, 21 May 2016 22:42:16 -0500 https://bioinformaticsonline.com/bookmarks/view/27463/bpipe-a-tool-for-running-and-managing-bioinformatics-pipelines <![CDATA[Bpipe - a tool for running and managing bioinformatics pipelines]]> Bpipe provides a platform for running big bioinformatics jobs that consist of a series of processing stages - known as 'pipelines'.

Bpipe has been published in Bioinformatics! If you use Bpipe, please cite:

Sadedin S, Pope B & Oshlack A, Bpipe: A Tool for Running and Managing Bioinformatics Pipelines, Bioinformatics

Address of the bookmark: http://docs.bpipe.org/

]]> Radha Agarkar https://bioinformaticsonline.com/videolist/watch/2349/bioinformatics-understanding-of-living-systems-through-information-science Wed, 14 Aug 2013 11:50:17 -0500 https://bioinformaticsonline.com/videolist/watch/2349/bioinformatics-understanding-of-living-systems-through-information-science <![CDATA[Bioinformatics -- Understanding of living systems through information science]]> Recently, the progress of the Human Genome Project, aiming to decode all human DNA sequences, has highlighted a research field called bioinformatics. In this new field, computers and techniques from information science are not just used as tools to advance life science research; they're expected to have a major impact on how we think about the life sciences. Q. The main feature of bioinformatics is, it utilizes computers to analyze life. One is example is the genome. In all organisms, DNA contains genetic information, and this is called the genome. But the amount of information involved is huge, so recently, it's been read using next-generation sequencers, and analyzed by computers. In bioinformatics research, what we do is utilize those genome information to investigate the principles of life. As an organism evolves, its genome sequence changes through sudden mutations. Additionally, at the genome level, mutations called rearrangements, such as inversions, transpositions, and duplications, occur. The genome comparison system developed by the Sakakibara Lab calculates homologous sequences called anchors, which are conserved between species. If the genome is considered as a long text, then anchors can be thought of as words. Q. We're coming to understand the genomes of various organisms - not just humans, but monkeys, chimpanzees, bacteria, and so on. The first method used to analyze a genome is comparing it with the genomes of other organisms, to see where it's the same and where it's different. In that way, the content of the genome is decoded bit by bit, using computers. By contrast, in our method, we've developed software called Murasaki, which we also use to analyze large genomes, by comparing them with those of other organisms. The Sakakibara Lab uses a next-generation sequencer at Keio University, along with a cluster machine with hundreds of CPUs. In this way, the Lab is analyzing genome mutations that cause cancer, and the genome of the natto production strain Bacillus subtilis. Until now, genome analysis could only be done in national-scale projects. But now, next-generation sequencer development has made genome analysis possible in an ordinary lab. In a world-first achievement, the Sakakibara Lab has decoded the natto bacillus genome, through analysis using Keio's next-generation sequencer. Q. In the future, biology and the life sciences may become almost entirely information science and computer science. And in healthcare, that may enable us, for example, to predict whether individuals are susceptible to cancer, or to certain lifestyle-related diseases, by understanding their personal genome data. So, I think it's amply possible that we can make use of such information effectively, to help people live longer and be free from disease, by thinking about their lifestyle habits. Bioinformatics is only two decades old. In this field, many areas are still unknown. Professor Sakakibara, having been involved since the beginning, will continue tackling new, challenging research projects.]]> https://bioinformaticsonline.com/videolist/watch/4043/what-is-bioinformatics Wed, 28 Aug 2013 06:53:05 -0500 https://bioinformaticsonline.com/videolist/watch/4043/what-is-bioinformatics <![CDATA[What is Bioinformatics?]]> Illustration and Animation: Rachel Robinson Script: Tiffany Trent Voice-over: Kris Monger Sound: Glisten Carefully by Guennadi Malyshevski]]> https://bioinformaticsonline.com/pages/view/42813/bioinformatics-in-africa-part5-nigeria Sat, 06 Feb 2021 21:13:47 -0600 https://bioinformaticsonline.com/pages/view/42813/bioinformatics-in-africa-part5-nigeria <![CDATA[Bioinformatics in Africa: Part5 - Nigeria]]> Covenant University (CU)­Ota:
Covenant University (with her enriching and growing state­of­the­art laboratories in the area of  science and technology, arts, business and social sciences) is presently the Best University in  Nigeria (Private University category), based on the recent over­all rating just concluded by the  Nigeria   University   Commission   (NUC).   Recently,   Covenant   University   has   initiated   the  establishment of a Centre for Applied Biotech, Bio­Informatics and Microbiology (CBBM) to be  situated at the University. The institute has been designed to be a Public­Private Partnership for a productive synergy b/w Academia, Industry and Government. The whole concept is still evolving  and more details will be release soon. As regards CBBM, a dedicated computing lab is in plan, but even our computing capacity is  presently enormous. In the department of Computer and Information Sciences, we have more than  250 Pentium 4 PCs set aside for teaching and research purposes. Furthermore, we have several  moderate speed PCs at the Postgraduate research lab and our engineering departments and units.  Our wet lab facilities is presently minimal (basic for teaching), the Centre requirement as it touches  the wet­laboratories is also set to upgrade this to basic tools expected at an international centre of learning.

University of Ibadan (UIB)­Ibadan:
There has been significant increase in the number of bioinformatics activities in Nigeria (and West Africa) since 2003 when the program was initiated by the West African Biotechnology Workshops Series (WABWS, http://www.wabw.org) at the University of Ibadan, Nigeria (in collaboration with  the South African National Bioinformatics Institute (SANBI, http:/www.sanbi.ac.za). Workshops  that were open to scientists from all African countries have seen a very high number of applications  from scientists based in West Africa. The encouraging desire to acquire cutting­edge skills to  computational process data and extract useful knowledge from genome projects led to the interest of  the West African Biotechnology Workshops (WABW) to develop an agenda to address the  bioinformatics skills gap among scientists in West Africa. An increased commitment from agencies  like NEPAD would be required in the provision of infrastructure to establish and sustain regional  and national networks.

University of Ilorin (UIL)­Ilorin:
The University of Ilorin was established in 1976 by the Federal Government of Nigeria.  Bioinformatics activities started at the University in February 2003 with the establishment of the  West African Bioinformatics Research Initiative (WABRI). However, progress has been rather slow  due to inadequate funding. We are mainly engaged in Bioinformatics training at the introductory  level and proteomics studies on various species of malaria parasites. Recently, we became interested  in comparative genome analysis of various species of  Plasmodium  and the comparison of  chloroquine sensitive and chloroquine resistant strains of Plasmodium falciparum. Other activities  and areas of interest can be seen on our website, http://www.wabri.org, although not all our  proposed interests have been fully implemented due to our level of funding.

Training:
The University of Ilorin has introduced M.Sc. and Ph.D. programmes in Computer Science (with  options in Bioinformatics). The programme is based in the Department of Computer Science and  emphasis is on the development of algorithms to solve problems in bioinformatics. The Covenant University offers M.Sc. and Ph.D in Computer Science with option in Bioinformatics  (Computational Biology). Furthermore, through affiliated departments, the CBBM is been design to award Diploma and Degree certificates in Biotechnology.

Web sites and links: http://www.covenantuniversity.com http://www.run.edu.ng http://www.uniben.edu http://www.wabri.org http://www.wabw.org http://www.unilorin.edu.ng http://www.wabri.org http://www.asopah.org

]]> BioStar https://bioinformaticsonline.com/pages/view/35805/python-learning-resources-for-bioinformatics-and-computational-biologist Fri, 02 Mar 2018 06:54:15 -0600 https://bioinformaticsonline.com/pages/view/35805/python-learning-resources-for-bioinformatics-and-computational-biologist <![CDATA[Python learning resources for bioinformatics and computational biologist !]]> Python is a general-purpose language, which means it can be used to build just about anything, which will be made easy with the right tools/libraries.

Professionally, Python is great for backend web development, data analysis, artificial intelligence, and scientific computing. Many developers have also used Python to build productivity tools, games, and desktop apps, so there are plenty of resources to help you learn how to do those as well.

For pros and cons visit http://www.bestprogramminglanguagefor.me/why-learn-python and http://bioinformaticsonline.com/discussion/view/459/python-vs-perl

More resources at https://github.com/CodementorIO/Python-Learning-Resources

Following are the list of useful python programming resources:

]]> Jit https://bioinformaticsonline.com/pages/view/36603/learning-python-programming-a-bioinformatician-perspective Mon, 14 May 2018 16:33:03 -0500 https://bioinformaticsonline.com/pages/view/36603/learning-python-programming-a-bioinformatician-perspective <![CDATA[Learning Python Programming - a bioinformatician perspective !]]> Python Programming is a general purpose programming language that is open source, flexible, powerful and easy to use. One of the most important features of python is its rich set of utilities and libraries for data processing and analytics tasks. In the current era of big biological data, python and biopython is getting more popularity due to its easy-to-use features which supports big data processing.

In this tutorial series article, I will explore features and packages of python which are widely used in the big data, NGS, and bioinformatics. I will also walk through a real biological example which shows NGS data processing with the help of python packages and programming.

Python has a couple of points to recommend it to biologists and scientists specifically:

  • It's widely used in the scientific community
  • It has a couple of very well designed libraries for doing complex scientific computing (although we won't encounter them in this book)
  • It lend itself well to being integrated with other, existing tools
  • It has features which make it easy to manipulate strings of characters (for example, strings of DNA bases and protein amino acid residues, which we as biologists are particularly fond of)

In general, following are some of the important features of python which makes it a perfect fit for rapid application development.

  • Python is interpreted language so the program does not need to be compiled. Interpreter parses the program code and generates the output.
  • Python is dynamically typed, so the variables types are defined automatically.
  • Python is strongly typed. So the developers need to cast the type manually.
  • Less code and more use makes it more acceptable.
  • Python is portable, extendable and scalable.

There are two major Python versions, Python 2 and Python 3. Python 2 and 3 are quite different. This tutorial uses Python 3, because it more semantically correct and supports newer features.

I will post tutorial on daily basis on this page. Check the sub-pages on right side.

]]> Rahul Nayak https://bioinformaticsonline.com/news/view/39606/amity-university-bioinformatics-summer-program-kolkata Tue, 11 Jun 2019 21:27:10 -0500 https://bioinformaticsonline.com/news/view/39606/amity-university-bioinformatics-summer-program-kolkata <![CDATA[Amity University Bioinformatics Summer Program - Kolkata]]> Registrations are now open for the 2019 Summer Bioinformatics Training program at Amity University, Kolkata. The program will focus on introductory topics for life science students. We will review important history, topics and challenges bioinformatics can help address in the context of basic research, discovery and industry.

Read more: https://edu.t-bio.info/amity-university-summer-bioinformatics-program-registrations-are-open/

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