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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/35805?offset=730</link>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/23121/senior-sas-programmer-urgent-role-permanant-welwyn-garden-city-uk</guid>
  <pubDate>Fri, 03 Jul 2015 08:14:23 -0500</pubDate>
  <link></link>
  <title><![CDATA[Senior SAS Programmer - URGENT ROLE - Permanant - Welwyn Garden City - UK]]></title>
  <description><![CDATA[
<p>SAS Programmer URGENTLY required !! My client is looking for an experienced Senior SAS Programmer, to join their bubbly dynamic team in Welwyn Garden City. You must have experience within SAS and/or R programming language. I am looking for someone with a background within either Life Sciences, Statistics, Computer Science, Bioinformatics etc. I am looking for someone with leadership qualities, you must have excellent analyst skills. Please call Dareen Evans on 01772 278050 or email your cv to dareen.evans@itworkshealth.co.uk</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/34552/edit-distance-application-in-bioinformatics</guid>
	<pubDate>Thu, 07 Dec 2017 08:46:51 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/34552/edit-distance-application-in-bioinformatics</link>
	<title><![CDATA[Edit distance application in bioinformatics !]]></title>
	<description><![CDATA[<p>There are other popular measures of&nbsp;<a href="https://en.wikipedia.org/wiki/Edit_distance" title="Edit distance">edit distance</a>, which are calculated using a different set of allowable edit operations. For instance,</p><ul>
<li>the&nbsp;<a href="https://en.wikipedia.org/wiki/Damerau%E2%80%93Levenshtein_distance" title="Damerau&ndash;Levenshtein distance">Damerau&ndash;Levenshtein distance</a>&nbsp;allows insertion, deletion, substitution, and the&nbsp;<a href="https://en.wikipedia.org/wiki/Transposition_(mathematics)" title="Transposition (mathematics)">transposition</a>&nbsp;of two adjacent characters;</li>
<li>the&nbsp;<a href="https://en.wikipedia.org/wiki/Longest_common_subsequence_problem" title="Longest common subsequence problem">longest common subsequence</a>&nbsp;(LCS) distance allows only insertion and deletion, not substitution;</li>
<li>the&nbsp;<a href="https://en.wikipedia.org/wiki/Hamming_distance" title="Hamming distance">Hamming distance</a>&nbsp;allows only substitution, hence, it only applies to strings of the same length.</li>
<li>the&nbsp;<a href="https://en.wikipedia.org/wiki/Jaro_distance" title="Jaro distance">Jaro distance</a>&nbsp;allows only&nbsp;<a href="https://en.wikipedia.org/wiki/Transposition_(mathematics)" title="Transposition (mathematics)">transposition</a>.</li>
</ul><p>&nbsp;</p><pre><span>use</span> Text<span>::</span>Levenshtein <span>qw</span><span>(</span>distance<span>);</span>

 <span>print</span> <span>distance</span><span>(</span><span>"foo"</span><span>,</span><span>"four"</span><span>);</span>
 <span># prints "2"</span>

 <span>my</span> <span>@words</span>     <span>=</span> <span>qw</span><span>/ four foo bar /</span><span>;</span>
 <span>my</span> <span>@distances</span> <span>=</span> <span>distance</span><span>(</span><span>"foo"</span><span>,</span><span>@words</span><span>);</span>

 <span>print</span> <span>"@distances"</span><span>;</span>
 <span># prints "2 0 3"</span><br /><br /><br /></pre><pre><span>use</span> Algorithm<span>::</span>LCSS <span>qw</span><span>(</span> LCSS CSS CSS_Sorted <span>);</span>
    <span>my</span> <span>$lcss_ary_ref</span> <span>=</span> <span>LCSS</span><span>(</span> <span>\</span><span>@SEQ1</span><span>,</span> <span>\</span><span>@SEQ2</span> <span>);</span>  <span># ref to array</span>
    <span>my</span> <span>$lcss_string</span>  <span>=</span> <span>LCSS</span><span>(</span> <span>$STR1</span><span>,</span> <span>$STR2</span> <span>);</span>    <span># string</span>
    <span>my</span> <span>$css_ary_ref</span> <span>=</span> <span>CSS</span><span>(</span> <span>\</span><span>@SEQ1</span><span>,</span> <span>\</span><span>@SEQ2</span> <span>);</span>    <span># ref to array of arrays</span>
    <span>my</span> <span>$css_str_ref</span> <span>=</span> <span>CSS</span><span>(</span> <span>$STR1</span><span>,</span> <span>$STR2</span> <span>);</span>      <span># ref to array of strings</span>
    <span>my</span> <span>$css_ary_ref</span> <span>=</span> <span>CSS_Sorted</span><span>(</span> <span>\</span><span>@SEQ1</span><span>,</span> <span>\</span><span>@SEQ2</span> <span>);</span>  <span># ref to array of arrays</span>
    <span>my</span> <span>$css_str_ref</span> <span>=</span> <span>CSS_Sorted</span><span>(</span> <span>$STR1</span><span>,</span> <span>$STR2</span> <span>);</span>    <span># ref to array of strings<br /><br /><br /><br /></span></pre><p>There are many different modules on CPAN for calculating the edit distance between two strings. Here's just a selection.</p><p><a href="http://search.cpan.org/perldoc?Text%3A%3ALevenshteinXS">Text::LevenshteinXS</a>&nbsp;and&nbsp;<a href="http://search.cpan.org/perldoc?Text%3A%3ALevenshtein%3A%3AXS">Text::Levenshtein::XS</a>&nbsp;are both versions of the Levenshtein algorithm that require a C compiler, but will be a lot faster than this module.</p><p>The Damerau-Levenshtein edit distance is like the Levenshtein distance, but in addition to insertion, deletion and substitution, it also considers the transposition of two adjacent characters to be a single edit. The module&nbsp;<a href="http://search.cpan.org/perldoc?Text%3A%3ALevenshtein%3A%3ADamerau">Text::Levenshtein::Damerau</a>&nbsp;defaults to using a pure perl implementation, but if you've installed&nbsp;<a href="http://search.cpan.org/perldoc?Text%3A%3ALevenshtein%3A%3ADamerau%3A%3AXS">Text::Levenshtein::Damerau::XS</a>&nbsp;then it will be a lot quicker.</p><p><a href="http://search.cpan.org/perldoc?Text%3A%3AWagnerFischer">Text::WagnerFischer</a>&nbsp;is an implementation of the Wagner-Fischer edit distance, which is similar to the Levenshtein, but applies different weights to each edit type.</p><p><a href="http://search.cpan.org/perldoc?Text%3A%3ABrew">Text::Brew</a>&nbsp;is an implementation of the Brew edit distance, which is another algorithm based on edit weights.</p><p><a href="http://search.cpan.org/perldoc?Text%3A%3AFuzzy">Text::Fuzzy</a>&nbsp;provides a number of operations for partial or fuzzy matching of text based on edit distance.&nbsp;<a href="http://search.cpan.org/perldoc?Text%3A%3AFuzzy%3A%3APP">Text::Fuzzy::PP</a>&nbsp;is a pure perl implementation of the same interface.</p><p><a href="http://search.cpan.org/perldoc?String%3A%3ASimilarity">String::Similarity</a>&nbsp;takes two strings and returns a value between 0 (meaning entirely different) and 1 (meaning identical). Apparently based on edit distance.</p><p><a href="http://search.cpan.org/perldoc?Text%3A%3ADice">Text::Dice</a>&nbsp;calculates&nbsp;<a href="https://en.wikipedia.org/wiki/S%C3%B8rensen%E2%80%93Dice_coefficient">Dice's coefficient</a>&nbsp;for two strings. This formula was originally developed to measure the similarity of two different populations in ecological research.</p><pre><span>&nbsp;</span></pre>]]></description>
	<dc:creator>Neel</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38472/gpsrdocker-docker-based-container-that-contain-all-softwareweb-servers-developed-in-the-field-of-bioinformatics</guid>
	<pubDate>Sun, 16 Dec 2018 13:04:46 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38472/gpsrdocker-docker-based-container-that-contain-all-softwareweb-servers-developed-in-the-field-of-bioinformatics</link>
	<title><![CDATA[gpsrdocker: docker-based container that contain all software/web servers developed in the field of bioinformatics.]]></title>
	<description><![CDATA[<p><span>GPSRdocker (</span><a href="http://webs.iiitd.edu.in/gpsrdocker/">http://webs.iiitd.edu.in/gpsrdocker/</a><span>) is&nbsp; Presently it contain software developed at G. P. S. Raghava's group (</span><a href="http://webs.iiitd.edu.in/raghava/">http://webs.iiitd.edu.in/raghava/</a><span>&nbsp;). </span></p>
<p><span>The programs and the package are free software for academic users. Permission to use, copy, and modify any part of this software for educational, research and non-profit purposes is hereby granted. In this package or Docker image, number of other supported software has been integrated which may be under other licenses, along with any direct or indirect dependencies of the primary software being contained. As for any pre-built image usage, it is the image user's responsibility to ensure that any use of this image complies with any relevant licenses for all software contained within. </span></p>
<p><span>All software packages are distributed in the hope that they will be useful but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. If you have any query, please contact at raghava@iiitd.ac.in.</span></p><p>Address of the bookmark: <a href="https://hub.docker.com/r/raghavagps/gpsrdocker/" rel="nofollow">https://hub.docker.com/r/raghavagps/gpsrdocker/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/39472/louisiana-biomedical-research-network-summer-bioinformatics-training-program</guid>
	<pubDate>Wed, 05 Jun 2019 15:30:01 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/39472/louisiana-biomedical-research-network-summer-bioinformatics-training-program</link>
	<title><![CDATA[Louisiana Biomedical Research Network: Summer Bioinformatics Training Program]]></title>
	<description><![CDATA[<p><img src="https://edu.t-bio.info/wp-content/uploads/2019/06/LBRN-Summer-Program1-CCT.jpg" alt="2019 summer bioinformatics training program" width="600" height="337.5" style="border: 0px;"></p><p>Louisiana Biomedical Research Network (LBRN) announces registration for it's Summer 2019 Bioinformatics Training Program. The program will be focused on processing, analysis and interpretation of next generation sequecning data for biologists. Learn more:</p><p>https://edu.t-bio.info/louisiana-biomedical-research-network-summer-2019-lbrn-bioinformatics-training-program/</p>]]></description>
	<dc:creator>eliabrodsky</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/40115/naegleria-fowleri-brain-eating-amoebae</guid>
	<pubDate>Thu, 10 Oct 2019 22:12:03 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/40115/naegleria-fowleri-brain-eating-amoebae</link>
	<title><![CDATA[Naegleria fowleri: brain eating amoebae]]></title>
	<description><![CDATA[<div><em>Naegleria fowleri</em>&nbsp;is a free living, universally distributed amoeba, which is mostly found in natural, stagnant, warm water bodies such as ponds, lakes, etc. It is also reported to be present even in indoor water bodies, such as swimming pools within a temperature range of 40&ndash;45&deg;C.&nbsp;</div><div>&nbsp;</div><div><img src="https://d.newsweek.com/en/full/351971/naegleria-fowleri.jpg" alt="image" width="720" height="634" style="border: 0px; border: 0px;">&nbsp;</div><div><em style="font-size: 12.8px;">N. fowleri</em>&nbsp;infects the central nervous system of human body by entering through the nose during swimming and outdoor baths in natural stagnant water bodies, leading to meningoencephalitis. It is a condition of inflammation of cerebral tissues and membranes of the brain and is mostly fatal in nature. Casualties due to N. fowleri infections are reported all across the globe including a few in India but only seven survivors in the entire world have been reported till 2015.</div><div>&nbsp;</div><div>You can find two genome assembly at&nbsp;</div><div><a href="https://www.ncbi.nlm.nih.gov/assembly/?term=naegleria%20fowleri">https://www.ncbi.nlm.nih.gov/assembly/?term=naegleria%20fowleri</a></div><div>&nbsp;</div><div>More at&nbsp;<a href="https://www.ncbi.nlm.nih.gov/search/all/?term=naegleria+fowleri">https://www.ncbi.nlm.nih.gov/search/all/?term=naegleria+fowleri</a></div>]]></description>
	<dc:creator>Neel</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/40957/multiple-phd-positions</guid>
  <pubDate>Sun, 09 Feb 2020 03:10:28 -0600</pubDate>
  <link></link>
  <title><![CDATA[Multiple PhD positions]]></title>
  <description><![CDATA[
<p>14 PhD positions in the EU Horizon 2020 Marie Skłodowska-Curie Project PRECODE:<br />International training network which sets a joint research programme to train a new generation of leading scientists in model systems and methods for the development of new therapies for pancreatic cancer (PaCa)</p>

<p>http://precode-project.eu/jobs-board/#1572451761376-39d75f63-c6fb</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/42166/software-for-genome-assembly</guid>
	<pubDate>Sun, 30 Aug 2020 09:51:38 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/42166/software-for-genome-assembly</link>
	<title><![CDATA[Software for genome assembly !]]></title>
	<description><![CDATA[<p>List of bioinformatics tools/Software Website References for genome assembly:</p><p>1 Falcon&nbsp;https://github.com/PacificBiosciences/pb-assembly</p><p>2 Canu assembler http://canu.readthedocs.io/en/latest/index.html</p><p>3 Miniasm assembler https://github.com/lh3/miniasm</p><p>4 PBJelly scaffolding tool https://sourceforge.net/projects/pb-jelly/</p><p>5 ARCS scaffolding tool https://github.com/bcgsc/arcs</p><p>6 Redundans reduction and scaffolding tool https://github.com/Gabaldonlab/redundans</p><p>7 Arrow error correction https://github.com/PacificBiosciences/ GenomicConsensus</p><p>8 PILON error correction https://github.com/broadinstitute/pilon/wiki</p><p>9 BUSCO single copy gene markers http://busco.ezlab.org/</p><p>10 Bandage graph assembly viewer https://rrwick.github.io/Bandage/</p><p>11 Gepard dotter http://cube.univie.ac.at/gepard</p><p>12 MUMmer aligner and plotter http://mummer.sourceforge.net/</p>]]></description>
	<dc:creator>LEGE</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/43256/senior-scientist-bioinformatics-eurofins-genomics-india-pvt-ltd-bengaluru</guid>
  <pubDate>Sat, 14 Aug 2021 13:17:36 -0500</pubDate>
  <link></link>
  <title><![CDATA[Senior Scientist bioinformatics @ Eurofins Genomics India Pvt Ltd, Bengaluru.]]></title>
  <description><![CDATA[
<p>Eurofins hiring @ Eurofins Genomics India Pvt Ltd, Bengaluru.</p>

<p>Designation: Senior Scientist bioinformatics<br />Experience: 8-9 years of experience in bioinformatics analysis of various NGS applications such as WGS, RNASeq, Metagenome, small RNA.</p>

<p>Location: Bangalore</p>

<p>Roles &amp; Responsibilities:<br />-Develop NGS pipeline for analysis and interpretation of NGS data<br />-Organizing and managing large scale genomic data<br />-Should have experience in NGS data analysis, such as WGS, RNASeq, Small RNA, Metagenome (16S, ITS, Whole metagenome)etc.<br />-Should also have good programming skills in perl or python, PHP,J Query, MySql.<br />-Manage project timelines and deliverables.<br />-Implement and execute data processing workflows and automate the pipelines.</p>

<p>If you are interested, please send your profile to me at arpitaghosh@eurofins.com with “Senior Scientist bioinformatics for Genomics” as the subject.</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/43890/immediate-opening-for-senior-and-lead-bioinformatics-engineers-at-medgenome</guid>
  <pubDate>Sat, 04 Jun 2022 09:00:57 -0500</pubDate>
  <link></link>
  <title><![CDATA[Immediate opening for senior and lead bioinformatics engineers at MedGenome]]></title>
  <description><![CDATA[
<p>Immediate opening for senior and lead bioinformatics engineers at MedGenome</p>

<p>Mandatory requirements<br />Knowledge of #Python,#PERL,#R (one or more) and shell environment (#linux )<br />Knowledge about database - #mysql, #oracle, #mongodb (one or more)<br />Past industry experience &gt;= 2 years or equivalent</p>

<p>Other skill sets<br />Knowledge of #nextflow and/or #snakemake<br />Basic knowledge of bioinformatics/genomics</p>

<p>Send your applications to careers@medgenome.com</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/43084/frequently-used-bioinformatics-tools-for-viral-genome-analysis</guid>
	<pubDate>Wed, 23 Jun 2021 07:40:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/43084/frequently-used-bioinformatics-tools-for-viral-genome-analysis</link>
	<title><![CDATA[Frequently used bioinformatics tools for viral genome analysis !]]></title>
	<description><![CDATA[<p><strong>IVA: accurate de novo assembly of RNA virus genomes.</strong><br /> Hunt M, Gall A, Ong SH, Brener J, Ferns B, Goulder P, Nastouli E, Keane JA, Kellam P, Otto TD.<br /> Bioinformatics. 2015 Jul 15;31(14):2374-6. doi: <a href="http://bioinformatics.oxfordjournals.org/content/31/14/2374.long">10.1093/bioinformatics/btv120</a>. Epub 2015 Feb 28.</p><p><a href="http://www.nature.com/nmeth/journal/v9/n1/full/nmeth.1814.html"><strong>Adapter sequences</strong></a>:<br /> <strong>Optimal enzymes for amplifying sequencing libraries.</strong><br /> Quail, M. a et al. Nat. Methods 9, 10-1 (2012).</p><p><a href="http://genome.cshlp.org/content/early/2012/01/12/gr.131383.111"><strong>GAGE</strong></a>:<br /> <strong>GAGE: A critical evaluation of genome assemblies and assembly algorithms.</strong><br /> Salzberg, S. L. et al. Genome Res. 22, 557-67 (2012).</p><p><a href="http://www.biomedcentral.com/1471-2105/14/160"><strong>KMC</strong></a>:<br /> <strong>Disk-based k-mer counting on a PC.</strong><br /> Deorowicz, S., Debudaj-Grabysz, A. &amp; Grabowski, S. BMC Bioinformatics 14, 160 (2013).</p><p><a href="http://genomebiology.com/2014/15/3/R46"><strong>Kraken</strong></a>:<br /> <strong>Kraken: ultrafast metagenomic sequence classification using exact alignments.</strong><br /> Wood, D. E. &amp; Salzberg, S. L. Genome Biol. 15, R46 (2014).</p><p><a href="http://genomebiology.com/2004/5/2/r12"><strong>MUMmer</strong></a>:<br /> <strong>Versatile and open software for comparing large genomes.</strong><br /> Kurtz, S. et al. Genome Biol. 5, R12 (2004).</p><p><strong>R</strong>:<br /> <strong>R: A language and environment for statistical computing.</strong><br /> R Core Team (2013). R Foundation for Statistical Computing, Vienna, Austria. URL <a href="http://www.R-project.org/">http://www.R-project.org/</a>.</p><p><a href="http://nar.oxfordjournals.org/content/39/9/e57"><strong>RATT</strong></a>:<br /> <strong>RATT: Rapid Annotation Transfer Tool.</strong><br /> Otto, T. D., Dillon, G. P., Degrave, W. S. &amp; Berriman, M. Nucleic Acids Res. 39, e57 (2011).</p><p><a href="http://bioinformatics.oxfordjournals.org/content/25/16/2078.abstract"><strong>SAMtools</strong></a>:<br /> <strong>The Sequence Alignment/Map format and SAMtools.</strong><br /> Li, H. et al. Bioinformatics 25, 2078-9 (2009).</p><p><a href="http://bioinformatics.oxfordjournals.org/content/early/2014/04/12/bioinformatics.btu170"><strong>Trimmomatic</strong></a>:<br /> <strong>Trimmomatic: A flexible trimmer for Illumina Sequence Data.</strong><br /> Bolger, A. M., Lohse, M. &amp; Usadel, B. Bioinformatics 1-7 (2014).</p>]]></description>
	<dc:creator>Neel</dc:creator>
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