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<channel>
	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/36607?offset=40</link>
	<atom:link href="https://bioinformaticsonline.com/related/36607?offset=40" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44318/proksee-in-depth-characterization-and-visualization-of-bacterial-genomes</guid>
	<pubDate>Tue, 09 May 2023 19:38:52 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44318/proksee-in-depth-characterization-and-visualization-of-bacterial-genomes</link>
	<title><![CDATA[Proksee: in-depth characterization and visualization of bacterial genomes]]></title>
	<description><![CDATA[<p><span>Proksee is an expert system for genome assembly, annotation and visualization. To begin using Proksee, provide a complete genome sequence, sequencing reads or a CGView/Proksee map JSON file.</span></p><p>Address of the bookmark: <a href="https://proksee.ca/" rel="nofollow">https://proksee.ca/</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/33903/visiting-scientist-computational-genomics</guid>
  <pubDate>Mon, 17 Jul 2017 07:20:18 -0500</pubDate>
  <link></link>
  <title><![CDATA[Visiting Scientist - Computational Genomics]]></title>
  <description><![CDATA[
<p>ICRISAT is a non-profit, non-political organization that conducts agricultural research for development in Asia and sub-Saharan Africa with a wide array of partners throughout the world. ICRISAT and its partners help empower those living in the semi-arid tropics, especially smallholder farmers, to overcome poverty, hunger, malnutrition and a degraded environment through more efficient and profitable agriculture. </p>

<p>ICRISAT is headquartered in Patancheru near Hyderabad, India, with two regional hubs and five country offices in sub-Saharan Africa. ICRISAT, established in 1972, is a member of the CGIAR Consortium. For more details, see www.icrisat.org.</p>

<p>Job Responsibilities:<br />Planning and execution of different NGS/genomics data analysis<br />Apply, maintain, and support cutting-edge pipelines for the analysis and interpretation of NGS data<br />Analyze large-scale genomic datasets generated internally and through collaboration with others<br />Genome wide analysis- LD analysis, hapmap, genetic map construction and qtl mapping<br />Expression analysis based on RNA-seq, gene ontology and metabolic pathway data<br />Sequence level analysis like gene family analysis, orthology/paralogy etc.<br />Familiarity with genomic and biological information databases<br />Compilation and interpretation of results and writing reports<br />Experience working independently and in a team environment<br />Requirements:</p>

<p>PhD or M.Sc with 2-3 years experience from reputed institute in the area of life science or similar Knowledge in Next Generation Sequencing (NGS) data analysis. Should be familiar with various sequencing platforms. Sound knowledge of genomics and molecular biology is must. Proficient in any one of the programming/scripting in languages: Python, Perl, PHP, R, Shell Scripting. Must be experienced in working on Linux and CLI environment. Ability to work as team as well as independently with minimal support. Fluency in spoken and written English is essential. </p>

<p>NGS techniques like sequence alignment, variant calling based on whole genome re-sequencing and genotyping-by-sequencing (GBS), RNA-Seq/transcriptome analysis<br />Knowledge of various standard NGS related tool<br />Ability to solve complex problems in advanced genomics research areas<br />Ease and interest in working with people from diverse backgrounds<br />Excellent oral/written communication and interpersonal/networking skills<br />General: <br />This position is contract for a period of two years.</p>

<p>How to apply:<br />Applicants should apply on or before 27-July-2017, with latest Curriculum Vitae, and the names and contact information of three references that are knowledgeable about your professional qualifications and work experience. All applications will be acknowledged, however only short listed candidates will be contacted<br />Please CLICK HERE to submit your application. <br />ICRISAT is an equal opportunity employer</p>

<p>http://icrisat.careersitemanager.com/job-listings-Visiting-Scientist-Computational-Genomics-ICRISAT-Hyderabad-Secunderabad-2-to-4-years-060717000278</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/35525/linux-commands-cheat-sheet-for-bioinformatics-and-computational-biology-professionals</guid>
	<pubDate>Mon, 05 Feb 2018 18:50:41 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/35525/linux-commands-cheat-sheet-for-bioinformatics-and-computational-biology-professionals</link>
	<title><![CDATA[Linux Commands Cheat Sheet for Bioinformatics and Computational Biology Professionals]]></title>
	<description><![CDATA[<p><span>The purpose of this cheat sheet is to introduce biologist and bioinformatician to the frequently used tools for NGS analysis as well as giving experience in writing one-liners.</span></p><ul>
<li><span></span><span><strong>File System</strong></span><span><strong><br /> </strong></span><span>ls</span><span>&nbsp;&mdash; list items in current directory</span><span><br /> </span><span>ls -l</span><span>&nbsp;&mdash; list items in current directory and show in long format to see perimissions, size, and modification date</span><span><br /> </span><span>ls -a</span><span>&nbsp;&mdash; list all items in current directory, including hidden files</span><span><br /> </span><span>ls -F</span><span>&nbsp;&mdash; list all items in current directory and show directories with a slash and executables with a star</span><span><br /> </span><span>ls dir</span><span>&nbsp;&mdash; list all items in directory dir</span><span><br /> </span><span>cd dir</span><span>&nbsp;&mdash; change directory to dir</span><span><br /> </span><span>cd ..</span><span>&nbsp;&mdash; go up one directory</span><span><br /> </span><span>cd /</span><span>&nbsp;&mdash; go to the root directory</span><span><br /> </span><span>cd ~</span><span>&nbsp;&mdash; go to to your home directory</span><span><br /> </span><span>cd -</span><span>&nbsp;&mdash; go to the last directory you were just in</span><span><br /> </span><span>pwd</span><span>&nbsp;&mdash; show present working directory</span><span><br /> </span><span>mkdir dir</span><span>&nbsp;&mdash; make directory dir</span><span><br /> </span><span>rm file</span><span>&nbsp;&mdash; remove file</span><span><br /> </span><span>rm -r dir</span><span>&nbsp;&mdash; remove directory dir recursively</span><span><br /> </span><span>cp file1 file2</span><span>&nbsp;&mdash; copy file1 to file2</span><span><br /> </span><span>cp -r dir1 dir2</span><span>&nbsp;&mdash; copy directory dir1 to dir2 recursively</span><span><br /> </span><span>mv file1 file2</span><span>&nbsp;&mdash; move (rename) file1 to file2</span><span><br /> </span><span>ln -s file link</span><span>&nbsp;&mdash; create symbolic link to file</span><span><br /> </span><span>touch file</span><span>&nbsp;&mdash; create or update file</span><span><br /> </span><span>cat file</span><span>&nbsp;&mdash; output the contents of file</span><span><br /> </span><span>less file</span><span>&nbsp;&mdash; view file with page navigation</span><span><br /> </span><span>head file</span><span>&nbsp;&mdash; output the first 10 lines of file</span><span><br /> </span><span>tail file</span><span>&nbsp;&mdash; output the last 10 lines of file</span><span><br /> </span><span>tail -f file</span><span>&nbsp;&mdash; output the contents of file as it grows, starting with the last 10 lines</span><span><br /> </span><span>vim file</span><span>&nbsp;&mdash; edit file</span><span><br /> </span><span>alias name 'command'</span><span>&nbsp;&mdash; create an alias for a command</span><span><br /> </span></li>
<li><span></span><span><strong>System</strong></span><span><strong><br /> </strong></span><span>shutdown</span><span>&nbsp;&mdash; shut down machine</span><span><br /> </span><span>reboot</span><span>&nbsp;&mdash; restart machine</span><span><br /> </span><span>date</span><span>&nbsp;&mdash; show the current date and time</span><span><br /> </span><span>whoami</span><span>&nbsp;&mdash; who you are logged in as</span><span><br /> </span><span>finger user</span><span>&nbsp;&mdash; display information about user</span><span><br /> </span><span>man command</span><span>&nbsp;&mdash; show the manual for command</span><span><br /> </span><span>df</span><span>&nbsp;&mdash; show disk usage</span><span><br /> </span><span>du</span><span>&nbsp;&mdash; show directory space usage</span><span><br /> </span><span>free</span><span>&nbsp;&mdash; show memory and swap usage</span><span><br /> </span><span>whereis app</span><span>&nbsp;&mdash; show possible locations of app</span><span><br /> </span><span>which app</span><span>&nbsp;&mdash; show which app will be run by default</span><span><br /> </span></li>
<li><span></span><span><strong>Process Management</strong></span><span><strong><br /> </strong></span><span>ps</span><span>&nbsp;&mdash; display your currently active processes</span><span><br /> </span><span>top</span><span>&nbsp;&mdash; display all running processes</span><span><br /> </span><span>kill pid</span><span>&nbsp;&mdash; kill process id pid</span><span><br /> </span><span>kill -9 pid</span><span>&nbsp;&mdash; force kill process id pid</span><span><br /> </span></li>
<li><span></span><span><strong>Permissions</strong></span><span><strong><br /> </strong></span><span>ls -l</span><span>&nbsp;&mdash; list items in current directory and show permissions</span><span><br /> </span><span>chmod ugo file</span><span>&nbsp;&mdash; change permissions of file to ugo - u is the user's permissions, g is the group's permissions, and o is everyone else's permissions. The values of u, g, and o can be any number between 0 and 7.</span><span><br /> </span><span>7</span><span>&nbsp;&mdash; full permissions</span><span><br /> </span><span>6</span><span>&nbsp;&mdash; read and write only</span><span><br /> </span><span>5</span><span>&nbsp;&mdash; read and execute only</span><span><br /> </span><span>4</span><span>&nbsp;&mdash; read only</span><span><br /> </span><span>3</span><span>&nbsp;&mdash; write and execute only</span><span><br /> </span><span>2</span><span>&nbsp;&mdash; write only</span><span><br /> </span><span>1</span><span>&nbsp;&mdash; execute only</span><span><br /> </span><span>0</span><span>&nbsp;&mdash; no permissions</span><span><br /> </span><span>chmod 600 file</span><span>&nbsp;&mdash; you can read and write - good for files</span><span><br /> </span><span>chmod 700 file</span><span>&nbsp;&mdash; you can read, write, and execute - good for scripts</span><span><br /> </span><span>chmod 644 file</span><span>&nbsp;&mdash; you can read and write, and everyone else can only read - good for web pages</span><span><br /> </span><span>chmod 755 file</span><span>&nbsp;&mdash; you can read, write, and execute, and everyone else can read and execute - good for programs that you want to share</span><span><br /> </span></li>
<li><span></span><span><strong>Networking</strong></span><span><strong><br /> </strong></span><span>wget file</span><span>&nbsp;&mdash; download a file</span><span><br /> </span><span>curl file</span><span>&nbsp;&mdash; download a file</span><span><br /> </span><span>scp user@host:file dir</span><span>&nbsp;&mdash; secure copy a file from remote server to the dir directory on your machine</span><span><br /> </span><span>scp file user@host:dir</span><span>&nbsp;&mdash; secure copy a file from your machine to the dir directory on a remote server</span><span><br /> </span><span>scp -r user@host:dir dir</span><span>&nbsp;&mdash; secure copy the directory dir from remote server to the directory dir on your machine</span><span><br /> </span><span>ssh user@host</span><span>&nbsp;&mdash; connect to host as user</span><span><br /> </span><span>ssh -p port user@host</span><span>&nbsp;&mdash; connect to host on port as user</span><span><br /> </span><span>ssh-copy-id user@host</span><span>&nbsp;&mdash; add your key to host for user to enable a keyed or passwordless login</span><span><br /> </span><span>ping host</span><span>&nbsp;&mdash; ping host and output results</span><span><br /> </span><span>whois domain</span><span>&nbsp;&mdash; get information for domain</span><span><br /> </span><span>dig domain</span><span>&nbsp;&mdash; get DNS information for domain</span><span><br /> </span><span>dig -x host</span><span>&nbsp;&mdash; reverse lookup host</span><span><br /> </span><span>lsof -i tcp:1337</span><span>&nbsp;&mdash; list all processes running on port 1337</span><span><br /> </span></li>
<li><span></span><span><strong>Searching</strong></span><span><strong><br /> </strong></span><span>grep pattern files</span><span>&nbsp;&mdash; search for pattern in files</span><span><br /> </span><span>grep -r pattern dir</span><span>&nbsp;&mdash; search recursively for pattern in dir</span><span><br /> </span><span>grep -rn pattern dir</span><span>&nbsp;&mdash; search recursively for pattern in dir and show the line number found</span><span><br /> </span><span>grep -r pattern dir --include='*.ext</span><span>&nbsp;&mdash; search recursively for pattern in dir and only search in files with .ext extension</span><span><br /> </span><span>command | grep pattern</span><span>&nbsp;&mdash; search for pattern in the output of command</span><span><br /> </span><span>find file</span><span>&nbsp;&mdash; find all instances of file in real system</span><span><br /> </span><span>locate file</span><span>&nbsp;&mdash; find all instances of file using indexed database built from the updatedb command. Much faster than find</span><span><br /> </span><span>sed -i 's/day/night/g' file</span><span>&nbsp;&mdash; find all occurrences of day in a file and replace them with night - s means substitude and g means global - sed also supports regular expressions</span><span><br /> </span></li>
<li><span></span><span><strong>Compression</strong></span><span><strong><br /> </strong></span><span>tar cf file.tar files</span><span>&nbsp;&mdash; create a tar named file.tar containing files</span><span><br /> </span><span>tar xf file.tar</span><span>&nbsp;&mdash; extract the files from file.tar</span><span><br /> </span><span>tar czf file.tar.gz files</span><span>&nbsp;&mdash; create a tar with Gzip compression</span><span><br /> </span><span>tar xzf file.tar.gz</span><span>&nbsp;&mdash; extract a tar using Gzip</span><span><br /> </span><span>gzip file</span><span>&nbsp;&mdash; compresses file and renames it to file.gz</span><span><br /> </span><span>gzip -d file.gz</span><span>&nbsp;&mdash; decompresses file.gz back to file</span><span><br /> </span></li>
<li><span></span><span><strong>Shortcuts</strong></span><span><strong><br /> </strong></span><span>ctrl+a</span><span>&nbsp;&mdash; move cursor to beginning of line</span><span><br /> </span><span>ctrl+f</span><span>&nbsp;&mdash; move cursor to end of line</span><span><br /> </span><span>alt+f</span><span>&nbsp;&mdash; move cursor forward 1 word</span><span><br /> </span><span>alt+b</span><span>&nbsp;&mdash; move cursor backward 1 word</span><span><br /> </span></li>
<li></li>
</ul>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/42137/plant-computational-genomics-lab-%E2%80%93-jill-wegrzyn</guid>
  <pubDate>Thu, 20 Aug 2020 19:49:12 -0500</pubDate>
  <link></link>
  <title><![CDATA[PLANT COMPUTATIONAL GENOMICS LAB – JILL WEGRZYN]]></title>
  <description><![CDATA[
<p>Our research focuses on the computational analysis of genomic and transcriptomic sequences from non-model plant species. We do this by developing approaches to examine gene finding, gene expression, transcriptome assembly, and conserved element identification, through machine learning and computational statistics. We use these novel methods to address questions related to genome biology and population genomics.</p>

<p>We also develop web-based applications that integrate data across domains to facilitate the forest geneticist or ecologist’s ability to analyze, share, and visualize their data. Such integration requires the implementation of semantic technologies and ontologies to connect genotype, phenotype, and environmental data.</p>

<p>http://plantcompgenomics.com/</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/42804/one-year-position-for-a-bioinformatician-computational-biologist-in-population-genetics</guid>
  <pubDate>Fri, 05 Feb 2021 11:19:02 -0600</pubDate>
  <link></link>
  <title><![CDATA[One-year position for a bioinformatician / computational biologist in population genetics]]></title>
  <description><![CDATA[
<p>The successful candidate will work as support staff mainly in the development, application and maintenance of pipelines for handling large omics datasets (including whole-genome sequences, high-density genotypes and mRNA sequences). These pipelines cover pre-processing of data, statistical analyses and genome bioinformatics. The postholder will also provide support in producing high-level graphic representations of<br />these data and of results from their analysis.  Our team is part of UMR<br />7268 ADES research unit (Anthropologie bio-culturelle, Droit, Ethique<br />et Sant=E9), located at the Timone Faculty of Medicine (Aix-Marseille<br />University, 13005 Marseille). </p>

<p>JOB QUALIFICATION<br />- PhD/Engineer/MSc in bioinformatics, biostatistics, genetics/genomics<br />  or any related field.<br />- Advanced knowledge of Bash/Perl scripting and job management on a Unix<br />  HPC and in at least one basic language for data<br />  manipulation/statistics (such as R/Python/Matlab) are required.<br />- Knowledge of at least one programming language (e.g. C), experience<br />  processing -omics data or skills in advanced graphical representation<br />  of data would be a plus.</p>

<p>DURATION<br />1 year, not extensible</p>

<p>SALARY<br />Gross salary is commensurate with experience and grade (MSc from<br />1,882=80/month and PhD/equivalent from 2,099=80/month).</p>

<p>APPLICATIONS/OPENING<br />Please send a motivation letter, a CV and the names of two referees to<br />pierre.faux@univ-amu.fr. The expected starting date is April 1st, 2021;<br />the job offer will however remain opened until the position is filled.</p>

<p>Pierre Faux</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/40882/troyanskaya-lab</guid>
  <pubDate>Tue, 04 Feb 2020 06:40:36 -0600</pubDate>
  <link></link>
  <title><![CDATA[Troyanskaya Lab]]></title>
  <description><![CDATA[
<p>The goal of our research is to interpret and distill this complexity through accurate analysis and modeling of molecular pathways, particularly those in which malfunctions lead to the manifestation of disease. We are inventing integrative methods for systems-level pathway modeling through integrative analysis of genome-scale datasets. We apply these approaches in studying challenging biological problems, such as how pathways function in diverse cell types and how they change dynamically.</p>

<p>https://function.princeton.edu/</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/file/view/989/bioinformatics-approach-to-boar-taint</guid>
	<pubDate>Wed, 17 Jul 2013 15:50:37 -0500</pubDate>
	<link>https://bioinformaticsonline.com/file/view/989/bioinformatics-approach-to-boar-taint</link>
	<title><![CDATA[Bioinformatics approach to Boar Taint]]></title>
	<description><![CDATA[<p><span>Meat products obtained from intact male pigs often produce offensive smell or odour which is recognized as a complex genetic trait called boar taint.Androstenone and Skatole&nbsp;in the fat primarily cause boar taint. Metabolism of androstenone and sex steroids share a common pathway which makes removal of boar taint a very challenging task. Castration is a traditional solution to remove boar taint but it also results in bad quality of meat due to low level of steroids which is objectionable to many consumers. Detected functional variant(s) underlying boar taint compounds can be used as genetic markers in selection of male pigs with reduced boar taint levels. Resequencing of a total of 47 samples belong to Norwegian Landrace (NL) and Duroc (D) pigs with varied boar taint levels were done in Illumina HiSeq2000 to &gt;10X average coverage. Short reads generated from these samples mapped to&nbsp;<em>Sus Scrofa</em>&nbsp;version 10.2 reference assembly using Bowtie2. Alignment file then used for calling SNPs and InDels inside previousy identified QTL regions on SSC5,13, and 7 with the aid of FreeBayes , a variant caller tool. A final list of SNPs was prepared after filtering SNPs on the basis of SNP quality, coverage of SNP allele, functional and structural annotation, and repeats, etc. Selected SNPs will be genotyped in sample population for validation and then used for constructing SNPs haplotypes in close linkage disequilibrium with QTLs and fine mapping of QTLs through association mapping of genotyped SNPs.</span><span>&nbsp;</span></p><p><span>&nbsp;</span></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
	<enclosure url="https://bioinformaticsonline.com/file/download/989" length="19688" type="image/jpeg" />
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/2518/genome-browsers</guid>
	<pubDate>Fri, 16 Aug 2013 19:04:47 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/2518/genome-browsers</link>
	<title><![CDATA[Genome Browsers]]></title>
	<description><![CDATA[<p>Genome Browser is the platform/database used for searching and retreiving sequences and annotation of genomes belong to various eukaryotes, prokaryotes, etc.</p><p>Following are the weblink for different available browsers:</p><p><a href="http://www.ensembl.org/index.html">http://www.ensembl.org/index.html</a></p><p><a href="http://ensemblgenomes.org/">http://ensemblgenomes.org/</a></p><p><a href="http://genome.ucsc.edu/">http://genome.ucsc.edu/</a></p><p><a href="http://www.ncbi.nlm.nih.gov/genome">http://www.ncbi.nlm.nih.gov/genome</a></p><p><a href="http://www.ebi.ac.uk/genomes/">http://www.ebi.ac.uk/genomes/</a></p><p><a href="http://flybase.org/">http://flybase.org/</a></p><p><a href="http://cmr.jcvi.org/tigr-scripts/CMR/CmrHomePage.cgi">http://cmr.jcvi.org/tigr-scripts/CMR/CmrHomePage.cgi</a></p><p><a href="http://www.sanger.ac.uk/resources/databases/">http://www.sanger.ac.uk/resources/databases/</a></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4297/how-genes-are-regulated-transcription-factors</guid>
	<pubDate>Thu, 05 Sep 2013 16:54:19 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4297/how-genes-are-regulated-transcription-factors</link>
	<title><![CDATA[How Genes are Regulated: Transcription Factors]]></title>
	<description><![CDATA[<iframe src="http://player.vimeo.com/video/30034882?byline=0" width="" height="" frameborder="0" webkitAllowFullScreen allowFullScreen></iframe>Each cell in our body inherits the same master copy of DNA, but different cell types use it differently. Transcription Factors help influence which genes are used in which cell. Understanding how these dynamic proteins physically interact with DNA allows us to better understand and model their binding to DNA and their regulation of gene expression.  Scientific Direction by the Wasserman Lab at the University of British Columbia: http://www.cmmt.ubc.ca/research/investigators/wasserman/lab  Animation and editing by Blair Lyons of Stroma Studios: http://www.stromastudios.com]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/4943/molecular-genetics-lecture</guid>
	<pubDate>Fri, 27 Sep 2013 04:24:45 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/4943/molecular-genetics-lecture</link>
	<title><![CDATA[Molecular Genetics Lecture]]></title>
	<description><![CDATA[<p><span>"Robert Sapolsky makes interdisciplinary connections between behavioral biology and molecular genetic influences. He relates protein synthesis and point mutations to microevolutionary change, and discusses conflicting theories of gradualism and punctuated equilibrium and the influence of epigenetics on development theories."&nbsp;</span></p>
<p><span>"<span><strong>Robert Sapolsky</strong> is an American neuroendocrinologist, professor of biology, neuroscience, and neurosurgery at Stanford University, researcher and author" ----Wikipedia</span></span></p><p>Address of the bookmark: <a href="http://www.youtube.com/watch?v=_dRXA1_e30o" rel="nofollow">http://www.youtube.com/watch?v=_dRXA1_e30o</a></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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