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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/37496?offset=250</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40389/sequila-cov-a-fast-and-scalable-library-for-depth-of-coverage-calculations</guid>
	<pubDate>Sun, 15 Dec 2019 10:19:35 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40389/sequila-cov-a-fast-and-scalable-library-for-depth-of-coverage-calculations</link>
	<title><![CDATA[SeQuiLa-cov: A fast and scalable library for depth of coverage calculations]]></title>
	<description><![CDATA[<p><span>The Docker image is available at&nbsp;</span><a href="https://hub.docker.com/r/biodatageeks/" target="">https://hub.docker.com/r/biodatageeks/</a><span>. Supplementary information on benchmarking procedure as well as test data are publicly accessible at the project documentation site&nbsp;</span><a href="http://biodatageeks.org/sequila/benchmarking/benchmarking.html#depth-of-coverage" target="">http://biodatageeks.org/sequila/benchmarking/benchmarking.html#depth-of-coverage</a><span>. An archival copy of the code and supporting data is also available via the GigaScience database GigaDB</span></p>
<p>&bull; Project name: SeQuiLa-cov</p>
<p>&bull; Project home page:&nbsp;<a href="http://biodatageeks.org/sequila/" target="">http://biodatageeks.org/sequila/</a></p>
<p>&bull; Source code repository:&nbsp;<a href="https://github.com/ZSI-Bio/bdg-sequila" target="">https://github.com/ZSI-Bio/bdg-sequila</a></p>
<p>&bull; Operating system: Platform independent</p>
<p>&bull; Programming language: Scala</p>
<p>&bull; Other requirements: Docker</p>
<p>&bull; License: Apache License 2.0</p><p>Address of the bookmark: <a href="https://academic.oup.com/gigascience/article/8/8/giz094/5543653" rel="nofollow">https://academic.oup.com/gigascience/article/8/8/giz094/5543653</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43856/puffaligner-a-fast-efficient-and-accurate-aligner-based-on-the-pufferfish-index</guid>
	<pubDate>Thu, 21 Apr 2022 05:41:39 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43856/puffaligner-a-fast-efficient-and-accurate-aligner-based-on-the-pufferfish-index</link>
	<title><![CDATA[PuffAligner: a fast, efficient and accurate aligner based on the Pufferfish index]]></title>
	<description><![CDATA[<p><span>PuffAligner, a fast, accurate and versatile aligner built on top of the Pufferfish index. PuffAligner is able to produce highly sensitive alignments, similar to those of Bowtie2, but much more quickly. While exhibiting similar speed to the ultrafast STAR aligner, PuffAligner requires considerably less memory to construct its index and align reads. PuffAligner strikes a desirable balance with respect to the time, space and accuracy tradeoffs made by different alignment tools and provides a promising foundation on which to test new alignment ideas over large collections of sequences.</span></p><p>Address of the bookmark: <a href="https://github.com/COMBINE-lab/pufferfish/tree/cigar-strings" rel="nofollow">https://github.com/COMBINE-lab/pufferfish/tree/cigar-strings</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44902/hite-a-fast-and-accurate-dynamic-boundary-adjustment-approach-for-full-length-transposable-elements-detection-and-annotation-in-genome-assemblies</guid>
	<pubDate>Sat, 20 Sep 2025 09:34:04 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44902/hite-a-fast-and-accurate-dynamic-boundary-adjustment-approach-for-full-length-transposable-elements-detection-and-annotation-in-genome-assemblies</link>
	<title><![CDATA[HiTE: a fast and accurate dynamic boundary adjustment approach for full-length Transposable Elements detection and annotation in Genome Assemblies]]></title>
	<description><![CDATA[<p dir="auto"><code>HiTE</code>&nbsp;is a Python software that uses a dynamic boundary adjustment approach to detect and annotate full-length Transposable Elements in Genome Assemblies. In comparison to other tools, HiTE demonstrates superior performance in detecting a greater number of full-length TEs.</p>
<div dir="auto">
<h2 dir="auto">panHiTE</h2>
<a href="https://github.com/CSU-KangHu/HiTE#panhite"></a></div>
<p dir="auto">We have developed panHiTE, a comprehensive and accurate pipeline for TE detection in large-scale population genomes. It has been successfully applied to hundreds of plant population genomes, demonstrating its effectiveness and scalability.</p>
<p dir="auto">For detailed instructions, please refer to the&nbsp;<a href="https://github.com/CSU-KangHu/HiTE/wiki/panHiTE-tutorial">panHiTE tutorial</a>.</p><p>Address of the bookmark: <a href="https://github.com/CSU-KangHu/HiTE" rel="nofollow">https://github.com/CSU-KangHu/HiTE</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40594/gfaviz-flexible-and-interactive-visualization-of-gfa-sequence-graphs</guid>
	<pubDate>Thu, 23 Jan 2020 07:33:46 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40594/gfaviz-flexible-and-interactive-visualization-of-gfa-sequence-graphs</link>
	<title><![CDATA[GfaViz: flexible and interactive visualization of GFA sequence graphs]]></title>
	<description><![CDATA[<p><span>GFA (Graphical Fragment Assembly) is an emerging standard format for representing sequence graphs. Although it was originally conceived as a format for sequence assembly (hence the name), and this remains its core application, it is more general, and able to represent many different types of sequence graphs, including scaffolding graphs, alignment graphs, variant graphs and splicing graphs.</span></p><p>Address of the bookmark: <a href="https://github.com/ggonnella/gfaviz" rel="nofollow">https://github.com/ggonnella/gfaviz</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/2791/ncbi-psi-blast-tutorial</guid>
	<pubDate>Fri, 23 Aug 2013 02:25:02 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/2791/ncbi-psi-blast-tutorial</link>
	<title><![CDATA[NCBI PSI-BLAST Tutorial]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/T3kHEieyylk" frameborder="0" allowfullscreen></iframe>http:--www.biotechnology.jhu.edu-
Tutorial for PSI-BLAST, an extension of BLAST that uses matrix algebra. BLAST is a cornerstone bioinformatics tool at NCBI. BLAST is the
Basic Local Alignment Search tool and will protein and DNA sequences that
are related to a sequence that the user provides.]]></description>
	
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26573/efficient-genome-searching-with-biostrings-and-the-bsgenome-data-package</guid>
	<pubDate>Mon, 07 Mar 2016 05:18:06 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26573/efficient-genome-searching-with-biostrings-and-the-bsgenome-data-package</link>
	<title><![CDATA[Efficient genome searching with Biostrings and the BSgenome data package]]></title>
	<description><![CDATA[<p>Address of the bookmark: <a href="https://www.bioconductor.org/packages/3.3/bioc/vignettes/BSgenome/inst/doc/GenomeSearching.pdf" rel="nofollow">https://www.bioconductor.org/packages/3.3/bioc/vignettes/BSgenome/inst/doc/GenomeSearching.pdf</a></p>]]></description>
	<dc:creator>Aasha</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44559/metagraph-ultra-scalable-framework-for-dna-search-alignment-assembly</guid>
	<pubDate>Sat, 08 Jun 2024 16:15:25 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44559/metagraph-ultra-scalable-framework-for-dna-search-alignment-assembly</link>
	<title><![CDATA[MetaGraph: Ultra Scalable Framework for DNA Search, Alignment, Assembly]]></title>
	<description><![CDATA[<p><span>The MetaGraph framework</span><span>&nbsp;is designed to work with a wide range of input data sets, indexing from a few samples up to the contents of entire archives with hundreds of thousands of records. The indexing workflow always follows the same principle, transforming single input samples into error-removed, refined sample graphs, which are then merged into a joint metagraph index. Each input sample is annotated in the joint index as a subgraph. This graph index enriched with metadata can then be used for downstream applications such as&nbsp;</span><a href="https://metagraph.ethz.ch/#query">sequence search</a><span>&nbsp;or&nbsp;</span><a href="https://metagraph.ethz.ch/#assembly">differential assembly</a><span>.</span></p>
<p><span>Searcg link&nbsp;https://metagraph.ethz.ch/search&nbsp;</span></p>
<p><span>Pre-print&nbsp;https://www.biorxiv.org/content/10.1101/2020.10.01.322164v4&nbsp;</span></p><p>Address of the bookmark: <a href="https://metagraph.ethz.ch/" rel="nofollow">https://metagraph.ethz.ch/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/42664/common-bioinformatics-interview-questions</guid>
	<pubDate>Sat, 23 Jan 2021 06:07:50 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/42664/common-bioinformatics-interview-questions</link>
	<title><![CDATA[Common Bioinformatics Interview Questions !]]></title>
	<description><![CDATA[<p>The possibility of an interview for a bioinformatics position in the life sciences may be very disquieting, but the same concerns emerge time and again in my experience. So, it is exceedingly worthwhile to plan for future bioinformatics interview questions. Doing this will really give you the advantage in obtaining the position.</p><p>The following 5 questions are those that I have heard many times during the job-search process. There is no reason for not planning responses in such situations.</p><p><strong>1. Tell Us About Yourself</strong><br />This is a very typical opener in interviews. It's a perfect question to ask, and getting something planned will really help you concentrate and ease in the conversation. However, you need to make sure that your response is applicable to the job you're interviewing.<br />It's probably better to keep your answer professional. Try to include these in the answer as well: where did your love of science and bioinformatics come from? How the heck did you end up in this field? Why programming and scripting ?</p><p><strong>2. What is your plan for your bioinformatics career? / How do you look at yourself in five years? / How are your personal objectives to accomplish these goals / What are the plan for your research fundings ?</strong></p><p>Your CV/resume has already impressed the selection panel if you have been invited for an interview. The questions from the bioinformatics interview team provide an incentive for you to market yourself and illustrate the work in question with the most appropriate knowledge.</p><p><strong>3. What do you understand about the job description/What would your suggested research path be if you were a successful candidate?</strong><br />Summarize the specifics of the advertised bioinformatics position in your own words. Follow on with some suggestions of how you want to extend your research and create your own projects within the community.</p><p><strong>4. Will you work as a group or do you want to work on your own?</strong><br />This requirement can vary from jobs to job, so when addressing, be alert. A company/research PI may need a bioinformatician that is able to work on a single project autonomously, or they may need a person who can help direct and organize a team. In your response, refer to the job description.</p><p><strong>5. What particular methods have you used to date with your experiments?</strong><br />You might have experience with all the laboratory techniques described in the job description, but stress the ones you highly experienced with. Highlight your professional abilities and stress that you are extremely capable of mastering new techniques with others ...</p><p>At the end of the day, remember that you're questioning the jury as well as they're interviewing you. You will ought to think of any questions you would like the interview panel to pose. This indicates that you have done your homework and serious about the position.</p><p>All the best for your future job interview.</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/933/world-of-omics</guid>
	<pubDate>Tue, 16 Jul 2013 17:11:48 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/933/world-of-omics</link>
	<title><![CDATA[World of Omics]]></title>
	<description><![CDATA[<p>How many variants of "omics" techniques presently in use ?</p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/4100/should-you-get-sequenced-not-all-bad-genes-predict-disease</guid>
	<pubDate>Thu, 29 Aug 2013 15:10:53 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/4100/should-you-get-sequenced-not-all-bad-genes-predict-disease</link>
	<title><![CDATA[Should you get sequenced? Not all bad genes predict disease]]></title>
	<description><![CDATA[<p><span>&ldquo;What we really don&rsquo;t know yet is whether the predictive aspects of the genome are going to turn out to be beneficial or potentially harmful&rdquo;</span></p>
<p><span><span>&ldquo;As we roll out genomic medicine we are fighting against this society-wide misconception that having the bad gene means you&rsquo;re going to get the disease. That&rsquo;s only true in a very few cases.&rdquo;</span></span></p>
<p><span><span><strong>Source</strong>:Today Health</span></span></p><p>Address of the bookmark: <a href="http://www.today.com/health/should-you-get-sequenced-not-all-bad-genes-predict-disease-8C11017154" rel="nofollow">http://www.today.com/health/should-you-get-sequenced-not-all-bad-genes-predict-disease-8C11017154</a></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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