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Should you get sequenced? Not all bad genes predict disease
By Rahul Agarwal 4104 days agowww.today.com - “What we really don’t know yet is whether the predictive aspects of the genome are going to turn out to be beneficial or potentially harmful” “As we roll out genomic medicine we are fighting against this society-wide...Comparison of Short Read De Novo Alignment Algorithms
By Rahul Agarwal 4112 days agobiochem218.stanford.edu - Excellent article to introduce different sequencing methods along with tools for de novo assembly of sequencing reads and their relevant references. Title: Comparison of Short Read De Novo Alignment Algorithms Author: Nikhil GopalRNA Bioinformatics and High Throughput Analysis Jena
Research Topics: High Throughput Sequencing Analysis Comparative Genomics Identification and Annotation of Non-coding RNAs Bioinformatic Analysis and System Biology of Viruses Coevolution of Proteins and RNAs Algorithmic...Bio-Rad Acquires GnuBIO
By Rahul Agarwal 3871 days agoGnuBIO-Developer of Droplet-Based DNA Sequencing TechnologyDeadly Human Pathogen Cryptococcus Sequenced
By Rahul Agarwal 3865 days agoCryptococcus neoformans is a fungus responsible for a million cases of pneumonia and meningitis every year- are so malleable and dangerousDrawback of Exome Sequencing
By Rahul Agarwal 3828 days agoSmaller Exome datasets were found to be worse performer than those from larger datasets (WGS)GraphMap - A highly sensitive and accurate mapper for long, error-prone reads
By Rahul Agarwal 3428 days ago Comments (1)github.com - GraphMap is a novel mapper targeted at aligning long, error-prone third-generation sequencing data.It is designed to handle Oxford Nanopore MinION 1d and 2d reads with very high sensitivity and accuracy, and also presents a significant...GRASS: a generic algorithm for scaffolding next-generation sequencing assemblies.
By Abhimanyu Singh 2742 days agogithub.com - GRASS (GeneRic ASsembly Scaffolder)-a novel algorithm for scaffolding second-generation sequencing assemblies capable of using diverse information sources. GRASS offers a mixed-integer programming formulation of the contig scaffolding problem, which...LRSDAY: Long-read Sequencing Data Analysis for Yeasts
By Poonam Mahapatra 1916 days agogithub.com - Long-read sequencing technologies have become increasingly popular in genome projects due to their strengths in resolving complex genomic regions. As a leading model organism with small genome size and great biotechnological importance, the budding...FiNGS: Filters for Next Generation Sequencing
By Neel 1366 days agogithub.com - Key features Filters SNVs from any variant caller to remove false positives Calculates metrics based on BAM files and provides filtering not possible with other tools Fully user-configurable filtering (including which filters to use and their...
