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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/38055?offset=90</link>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/38590/senior-bioinformatics-scientist-strand-life-sciences-bangalore-india</guid>
  <pubDate>Wed, 02 Jan 2019 09:23:49 -0600</pubDate>
  <link></link>
  <title><![CDATA[Senior Bioinformatics Scientist @ Strand Life Sciences -- Bangalore, India]]></title>
  <description><![CDATA[
<p>RESPONSIBILITIES<br />The candidate is expected to work on a variety of projects related to analysis of data from NGS, Mass Spectrometry, Flow Cytometry and other related modalities. The position expects hands-on work and a strong eye for detail. The candidate will be able to contribute to impactful work spanning patient care, clinical research, and new assay and method development.<br />REQUIREMENTS<br />A PhD in a quantitative field (statistics, math, bioinformatics, computer science, physics or similar) and work experience or post-doc experience handling high throughout genomics data.<br />PREFERENCES<br />Experience in working in inter-disciplinary groups and ability to author research publications are additional desired qualities.<br />LOCALE<br />The position is in Bangalore and reports to the Chief Scientific Officer.<br />HOW TO APPLY<br />Write to ramesh[at]strandls.com.</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32134/lifemap</guid>
	<pubDate>Mon, 10 Apr 2017 05:42:37 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32134/lifemap</link>
	<title><![CDATA[Lifemap]]></title>
	<description><![CDATA[<p><strong>Lifemap</strong> is an interactive tool to explore the WHOLE NCBI TAXONOMY. The concept used in <strong>Lifemap</strong> is similar to the one used in cartography with tools like Google Maps&copy; or Open Street Maps: exploring is done by zooming and panning.</p>
<div>
<p>&nbsp;The current tree contains ALL species present in NCBI taxonomy as of <span style="text-decoration: underline;">October 18th, 2016</span>: 1,135,169 species including 10,545 Archaea, 418,777 Bacteria and 705,847 Eukaryotes. The Lifemap tree is updated every two weeks.</p>
</div>
<p>&nbsp;All the nodes in the tree are clickable. This displays various information and options:</p>
<ul>
<li>The species name (and the associated common name if there is one)</li>
<li>The rank (kingdom, family, class, species...)</li>
<li>Ability to go to the corresponding node/species on NCBI web site (displayed in a new window)</li>
<li>Possibility to download the corresponding subtree in newick extended format</li>
<li>Possibilty to get the whole lineage from the current node/tip to the root of the tree.</li>
</ul><p>Address of the bookmark: <a href="http://lifemap-ncbi.univ-lyon1.fr/" rel="nofollow">http://lifemap-ncbi.univ-lyon1.fr/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/41899/stay-at-home-revbayes-workshop</guid>
  <pubDate>Sat, 20 Jun 2020 11:53:24 -0500</pubDate>
  <link></link>
  <title><![CDATA[Stay-at-Home RevBayes Workshop]]></title>
  <description><![CDATA[
<p>Stay-at-Home RevBayes Workshop<br />Location: Anywhere (online-only event)<br />Dates: 7/13, 2020 to 8/12, 2020<br />Instructors: Joëlle Barido-Sottani, Walker Pett, Josh Justison, Wade Dismukes, Luiza Fabreti, Tracy Heath, Jeremy M. Brown, Rosana Zenil-Ferguson<br />Register: https://iastate.qualtrics.com/jfe/form/SV_02sCYRWbxYK9I5D</p>

<p>Description<br />This free online-only RevBayes workshop will provide an introduction to the theory and use of RevBayes, with a focus on (1) tree inference from molecular data, (2) analyses combining fossil and extant taxa, and (3) evaluating MCMC performance, with advanced topics including assessing model adequacy and macroevolutionary analyses. Additional topics may be added depending on the interests of selected participants. The format will be a combination of interactive video sessions (via Zoom or similar tools), real-time discussions over Slack, self-guided tutorials, and pre-recorded videos.</p>

<p>The initial session will resolve technical issues and present the basics of using RevBayes. Participants will then be expected to work through several tutorials on their own schedule, with the help of pre-recorded materials. A Slack forum will be open for questions and issues. The workshop will conclude with several online Q&amp;A sessions with the instructors. The dates for the interactive sessions are currently tentative and may be adjusted depending on the schedules of the participants and instructors.</p>

<p>We are hoping to identify up to 15 participants for this online course. While we hope we are able to accommodate everyone who applies, we realize that this may not be possible because of time-zones and availability. If the number of applicants exceeds our capacity, we hope to organize a second round of sessions later in the year. Participants will not be charged for the course, but we will request that they commit to completing the tutorials and attending a majority of interactive sessions.</p>

<p>To apply to this course, please go to the registration form and submit your application by July 6, 2020.</p>

<p>More at https://revbayes.github.io/workshops/online2020.html</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40946/free-genomics-data</guid>
	<pubDate>Fri, 07 Feb 2020 14:08:31 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40946/free-genomics-data</link>
	<title><![CDATA[Free Genomics data !]]></title>
	<description><![CDATA[<p><span>The specimens were collected by the Oxford Wytham Woods and Edinburgh Lohse lab teams. DNA extraction and sequencing was carried out by the Sanger Institute Scientific Operations teams. Assemblies were carried out by the Tree of Life team (Shane McCarthy) and colleagues in Pacific Biosciences (Jonas Korlach).</span></p>
<p><a href="https://www.darwintreeoflife.org/an-initial-set-of-raw-genome-assemblies-from-the-darwin-tree-of-life-project/">https://www.darwintreeoflife.org/an-initial-set-of-raw-genome-assemblies-from-the-darwin-tree-of-life-project/</a></p><p>Address of the bookmark: <a href="https://www.darwintreeoflife.org/an-initial-set-of-raw-genome-assemblies-from-the-darwin-tree-of-life-project/" rel="nofollow">https://www.darwintreeoflife.org/an-initial-set-of-raw-genome-assemblies-from-the-darwin-tree-of-life-project/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44513/mike-an-ultrafast-assembly-and-alignment-free-approach-for-phylogenetic-tree-construction</guid>
	<pubDate>Mon, 08 Apr 2024 06:19:52 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44513/mike-an-ultrafast-assembly-and-alignment-free-approach-for-phylogenetic-tree-construction</link>
	<title><![CDATA[MIKE: an ultrafast, assembly-, and alignment-free approach for phylogenetic tree construction]]></title>
	<description><![CDATA[<p><span>MIKE (MinHash-based&nbsp;</span><em>k</em><span>-mer algorithm). This algorithm is designed for the swift calculation of the Jaccard coefficient directly from raw sequencing reads and enables the construction of phylogenetic trees based on the resultant Jaccard coefficient. Simulation results highlight the superior speed of MIKE compared to existing state-of-the-art methods. We used MIKE to reconstruct a phylogenetic tree, incorporating 238 yeast, 303&nbsp;</span><em>Zea</em><span>, 141&nbsp;</span><em>Ficus</em><span>, 67&nbsp;</span><em>Oryza</em><span>, and 43&nbsp;</span><em>Saccharum spontaneum</em><span>&nbsp;samples. MIKE demonstrated accurate performance across varying evolutionary scales, reproductive modes, and ploidy levels, proving itself as a powerful tool for phylogenetic tree construction.</span></p><p>Address of the bookmark: <a href="https://github.com/Argonum-Clever2/mike" rel="nofollow">https://github.com/Argonum-Clever2/mike</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32849/car-reconstructing-contiguous-regions-of-an-ancestral-genome</guid>
	<pubDate>Thu, 18 May 2017 05:24:01 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32849/car-reconstructing-contiguous-regions-of-an-ancestral-genome</link>
	<title><![CDATA[CAR: Reconstructing Contiguous Regions of an Ancestral Genome]]></title>
	<description><![CDATA[<div id="abstract-1">
<p id="p-5">We describe a new method for predicting the ancestral order and orientation of those intervals from their observed adjacencies in modern species. We combine the results from this method with data from chromosome painting experiments to produce a map of an early mammalian genome that accounts for 96.8% of the available human genome sequence data. The precision is further increased by mapping inversions as small as 31 bp. Analysis of the predicted evolutionary breakpoints in the human lineage confirms certain published observations but disagrees with others. Although only a few mammalian genomes are currently sequenced to high precision, our theoretical analyses and computer simulations indicate that our results are reasonably accurate and that they will become highly accurate in the foreseeable future. Our methods were developed as part of a project to reconstruct the genome sequence of the last ancestor of human, dogs, and most other placental mammals;</p>
</div><p>Address of the bookmark: <a href="http://www.bx.psu.edu/miller_lab/car/" rel="nofollow">http://www.bx.psu.edu/miller_lab/car/</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/35823/regen-ancestral-genome-reconstruction-for-bacteria</guid>
	<pubDate>Tue, 06 Mar 2018 05:02:36 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/35823/regen-ancestral-genome-reconstruction-for-bacteria</link>
	<title><![CDATA[REGEN: Ancestral Genome Reconstruction for Bacteria]]></title>
	<description><![CDATA[<p><span>REGEN infers evolutionary events, including gene creation and deletion and replicon fission and fusion. The reconstruction can be performed by either a maximum parsimony or a maximum likelihood method. Gene content reconstruction is based on the concept of neighboring gene pairs. REGEN was designed to be used with any set of genomes that are sufficiently related, which will usually be the case for bacteria within the same taxonomic order.&nbsp;</span></p><p>Address of the bookmark: <a href="http://www.mdpi.com/2073-4425/3/3/423" rel="nofollow">http://www.mdpi.com/2073-4425/3/3/423</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/33960/mgra-breakpoint-graphs-and-ancestral-genome-reconstructions</guid>
	<pubDate>Tue, 25 Jul 2017 08:48:25 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/33960/mgra-breakpoint-graphs-and-ancestral-genome-reconstructions</link>
	<title><![CDATA[MGRA: Breakpoint graphs and ancestral genome reconstructions]]></title>
	<description><![CDATA[<p>MGRA (Multiple Genome Rearrangements and Ancestors) is a tool for reconstruction of ancestor genomes and evolutionary history of extant genomes.</p>
<p>It takes as an input a set of genomes represented as sequences of genes (or synteny blocks) and produces such sequences for ancestral genomes at the internal nodes of the phylogenetic tree.</p>
<p>The phylogenetic tree may be also specified completely or partially, in the latter case MGRA can reconstruct conserved ancestral regions (CARs) of the ancestral genome of interest.</p>
<p>Since version 2 MGRA supports gene insertion and deletions in addition to genome rearrangements and allows the input genomes to have different gene content.</p>
<p>It also can reconstruct most plausible phylogenetic tree based on the rearrangement characters.</p><p>Address of the bookmark: <a href="http://mgra.cblab.org/" rel="nofollow">http://mgra.cblab.org/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/34685/tools-for-bacterial-whole-genome-annotation</guid>
	<pubDate>Sat, 16 Dec 2017 17:37:47 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/34685/tools-for-bacterial-whole-genome-annotation</link>
	<title><![CDATA[Tools for bacterial whole genome annotation]]></title>
	<description><![CDATA[<p><a href="http://rast.nmpdr.org/">RAST</a>&nbsp;&ndash;&nbsp;Web tool (upload contigs), uses the subsystems in the SEED database and&nbsp;provides detailed annotation and pathway analysis. Takes several hours per genome but I think this is the best way to get a high quality annotation (if you have only a few genomes to annotate).</p><p><a href="http://www.vicbioinformatics.com/software.prokka.shtml">Prokka</a>&nbsp;&ndash;&nbsp;Standalone command line tool, takes just a few minutes per genome.&nbsp;This is the best way to get good quality annotation in a flash, which is particularly useful if you have loads of genomes or need to annotate a pangenome or metagenome. Note however that the quality of functional information is not as good as RAST, and you&nbsp;will need several extra steps if you want to do&nbsp;functional profiling and pathway analysis of your genome(s)&hellip; which is in-built in RAST.</p><p>NCBI Prokaryotic Genome Annotation Pipeline is designed to annotate bacterial and archaeal genomes (chromosomes and plasmids).</p><p>Genome annotation is a multi-level process that includes prediction of protein-coding genes, as well as other functional genome units such as structural RNAs, tRNAs, small RNAs, pseudogenes, control regions, direct and inverted repeats, insertion sequences, transposons and other mobile elements.</p><p><a href="https://www.ncbi.nlm.nih.gov/genome/annotation_prok/">PGAP</a>: NCBI has developed an automatic prokaryotic genome annotation pipeline that combines&nbsp;<em>ab initio</em>&nbsp;gene prediction algorithms with homology based methods. The first version of NCBI Prokaryotic Genome Automatic Annotation Pipeline (PGAAP;&nbsp;<a href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=18416670">see Pubmed Article</a>) developed in 2005 has been replaced with an upgraded version that is capable of processing a larger data volume.&nbsp; NCBI's annotation pipeline depends on several internal databases and is not currently available for download or use outside of the NCBI environment.</p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC453985">BEACON</a> (automated tool for Bacterial GEnome Annotation ComparisON), a fast tool for an automated and a systematic comparison of different annotations of single genomes. The extended annotation assigns putative functions to many genes with unknown functions. BEACON is available under GNU General Public License version 3.0 and is accessible at:&nbsp;<a href="http://www.cbrc.kaust.edu.sa/BEACON/" target="pmc_ext">http://www.cbrc.kaust.edu.sa/BEACON/</a>.</p><p><a href="http://www.kegg.jp/blastkoala/">BlastKOLA</a>: Assigns K numbers to the user's sequence data by BLAST searches, respectively, against a nonredundant set of KEGG GENES. KOALA (KEGG Orthology And Links Annotation) is KEGG's internal annotation tool for K number assignment of KEGG GENES using SSEARCH computation. Annotate Sequence in KEGG Mapper and Pathogen Checker in KEGG Pathogen are special interfaces to this server and can be executed in an interactive mode. BlastKOALA is suitable for annotating fully sequenced genomes.</p><p><a href="http://www.sanger.ac.uk/science/tools/pagit">PAGIT</a>: Provides a toolkit for improving the quality of genome assemblies created via an assembly software. PAGIT compiled four tools: (i) ABACAS which classifies and orientates contigs and estimates the sizes of gaps between them; (ii) IMAGE uses paired-end reads to extend contigs and close gaps within the scaffolds; (iii) ICORN for identifying and correcting small errors in consensus sequences and; (iv) RATT for help annotation. The software was mainly created to analyze parasite genomes of up to about 300 Mb.</p><p><a href="http://www.yandell-lab.org/software/maker.html">MAKER: </a>A portable and easily configurable genome annotation pipeline. MAKER allows smaller eukaryotic and prokaryotic genome projects to independently annotate their genomes and to create genome databases. It identifies repeats, aligns ESTs and proteins to a genome, produces ab-initio gene predictions and automatically synthesizes these data into gene annotations having evidence-based quality values. MAKER's inputs are minimal and its ouputs can be directly loaded into a Generic Model Organism Database (GMOD). They can also be viewed in the Apollo genome browser; this feature of MAKER provides an easy means to annotate, view and edit individual contigs and BACs without the overhead of a database. MAKER is available for download and can be tested online via the MAKER Web Annotation Service (MWAS).</p><p><a href="https://www.sciencedirect.com/science/article/pii/S0167701215001207">MyPro</a> is a software pipeline for high-quality prokaryotic genome assembly and annotation. It was validated on 18 oral streptococcal strains to produce submission-ready, annotated draft genomes. MyPro installed as a virtual machine and supported by updated databases will enable biologists to perform quality prokaryotic genome assembly and annotation with ease.</p>]]></description>
	<dc:creator>Radha Agarkar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42042/cluego-a-cytoscape-plug-in-that-visualizes-the-non-redundant-biological-terms-for-large-clusters-of-genes</guid>
	<pubDate>Thu, 13 Aug 2020 10:24:29 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42042/cluego-a-cytoscape-plug-in-that-visualizes-the-non-redundant-biological-terms-for-large-clusters-of-genes</link>
	<title><![CDATA[ClueGO: a Cytoscape plug-in that visualizes the non-redundant biological terms for large clusters of genes]]></title>
	<description><![CDATA[<p>ClueGO is a Cytoscape plug-in that visualizes the non-redundant biological terms for large clusters of genes in a functionally grouped network and it can be used in combination with GOlorize. The identifiers can be uploaded from a text file or interactively from a network of Cytoscape. The type of identifiers supported can be easely extended by the user. ClueGO performs single cluster analysis and comparison of clusters. From the ontology sources used, the terms are selected by different filter criteria. The related terms which share similar associated genes can be fused to reduce redundancy. The ClueGO network is created with kappa statistics and reflects the relationships between the terms based on the similarity of their associated genes. On the network, the node colour can be switched between functional groups and clusters distribution. ClueGO charts are underlying the specificity and the common aspects of the biological role. The significance of the terms and groups is automatically calculated. ClueGO is easy updatable with the newest files from Gene Ontology and KEGG.</p><p>Address of the bookmark: <a href="http://www.ici.upmc.fr/cluego/" rel="nofollow">http://www.ici.upmc.fr/cluego/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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