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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/38226?offset=30</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/27713/mutabind</guid>
	<pubDate>Mon, 06 Jun 2016 13:34:09 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/27713/mutabind</link>
	<title><![CDATA[MutaBind]]></title>
	<description><![CDATA[<p><span>MutaBind is a new computational method and server created through NCBI research efforts that maps mutations on a protein structural complex, calculates changes in binding affinity, identifies deleterious mutations and produces a downloadable mutant structural model.&nbsp;</span><a href="http://www.ncbi.nlm.nih.gov/projects/mutabind/index.fcgi/" target="_blank">http://www.ncbi.nlm.nih.gov/projects/mutabind/index.fcgi/</a></p><p><img src="http://www.ncbi.nlm.nih.gov/projects/mutabind/prj-sunddg/static/myimgs/CirclesDiamondBlueThiner.png" width="471" height="258" alt="image" style="border: 0px;"></p><p><span>MutaBind guides you through this process, step by step, starting with selecting a protein complex and inputting PDB code or uploading PDB files. You can also retrieve results with a job ID number, view help documents, and review the MutaBind method and references.</span></p><p><span>More at&nbsp;http://www.ncbi.nlm.nih.gov/projects/mutabind/index.fcgi/</span></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32730/ncbi-prokaryotic-genome-annotation-pipeline</guid>
	<pubDate>Tue, 16 May 2017 08:56:03 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32730/ncbi-prokaryotic-genome-annotation-pipeline</link>
	<title><![CDATA[NCBI Prokaryotic Genome Annotation Pipeline]]></title>
	<description><![CDATA[<p>NCBI Prokaryotic Genome Annotation Pipeline is designed to annotate bacterial and archaeal genomes (chromosomes and plasmids).</p>
<p>Genome annotation is a multi-level process that includes prediction of protein-coding genes, as well as other functional genome units such as structural RNAs, tRNAs, small RNAs, pseudogenes, control regions, direct and inverted repeats, insertion sequences, transposons and other mobile elements.</p>
<p>NCBI has developed an automatic prokaryotic genome annotation pipeline that combines&nbsp;<em>ab initio</em>&nbsp;gene prediction algorithms with homology based methods. The first version of NCBI Prokaryotic Genome Automatic Annotation Pipeline (PGAAP;&nbsp;<a href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&amp;db=pubmed&amp;dopt=Abstract&amp;list_uids=18416670">see Pubmed Article</a>) developed in 2005 has been replaced with an upgraded version that is capable of processing a larger data volume. You can find a more detailed description of the new version of&nbsp;the pipeline in&nbsp;<a href="https://www.ncbi.nlm.nih.gov/books/NBK174280/">NCBI Handbook chapter</a>. NCBI's annotation pipeline depends on several internal databases and is not currently available for download or use outside of the NCBI environment.</p>
<p>https://www.ncbi.nlm.nih.gov/genome/annotation_prok/</p><p>Address of the bookmark: <a href="https://www.ncbi.nlm.nih.gov/genome/annotation_prok/" rel="nofollow">https://www.ncbi.nlm.nih.gov/genome/annotation_prok/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/40596/igblast-a-popular-ncbi-package-for-classifying-and-analyzing-immunoglobulin-ig-and-t-cell-receptor-tcr-variable-domain-sequences</guid>
	<pubDate>Thu, 23 Jan 2020 11:34:37 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/40596/igblast-a-popular-ncbi-package-for-classifying-and-analyzing-immunoglobulin-ig-and-t-cell-receptor-tcr-variable-domain-sequences</link>
	<title><![CDATA[IgBLAST: a popular NCBI package for classifying and analyzing immunoglobulin (IG) and T cell receptor (TCR) variable domain sequences]]></title>
	<description><![CDATA[<p>NCBI team released a new version of IgBLAST with four new improvements. IgBLAST is a popular NCBI package for classifying and analyzing immunoglobulin (IG) and T cell receptor (TCR) variable domain sequences. Improvements are:<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>&nbsp;&nbsp;&nbsp; 1. Support for the new FWR4 annotation feature in the AIRR format, both in standard format and in the AIRR alignment format.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>&nbsp;&nbsp;&nbsp; 2. The previous &ldquo;-penalty&rdquo; parameter was renamed as -V_penalty to be consistent with other IgBLAST penalty options.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>&nbsp;&nbsp;&nbsp; 3. Restored constant internal BLAST search parameters for domain annotation (i.e., FWR/CDR) such that this process is not influenced by user parameters.<span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p>&nbsp;&nbsp;&nbsp; 4. Corrected FWR/CDR annotations for certain mouse VK and rat VH germline genes.<span style="font-size: 12.8px;">&nbsp;</span></p><p><span style="text-decoration: underline;"></span></p><p>IgBLAST 1.15.0 is available for&nbsp;<a href="https://ftp.ncbi.nih.gov/blast/executables/igblast/release/LATEST/" target="_blank">download</a>&nbsp;from the BLAST FTP area. See the the new&nbsp;<a href="https://ncbi.github.io/igblast/" target="_blank">manual</a>&nbsp;on GitHub for information about setting up and running IgBLAST.</p><p><span style="text-decoration: underline;"></span></p><p>&nbsp;If you have any questions or concerns, please contact&nbsp;<a href="mailto:blast-help@ncbi.nlm.nih.gov" target="_blank" title="Follow link">blast-help@ncbi.nlm.nih.gov</a><span style="text-decoration: underline;"></span><span style="text-decoration: underline;"></span></p><p><span style="text-decoration: underline;"></span>&nbsp;</p>]]></description>
	<dc:creator>BioJoker</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/44342/ncbi-datasets%E2%80%AFpages</guid>
	<pubDate>Wed, 12 Jul 2023 06:29:31 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/44342/ncbi-datasets%E2%80%AFpages</link>
	<title><![CDATA[NCBI Datasets pages]]></title>
	<description><![CDATA[<p>Update! Assembly and Genome record pages now redirect to new NCBI Datasets pages. NCBI Datasets is a new resource that makes it easier to find and download genome data. Learn more: https://ncbiinsights.ncbi.nlm.nih.gov/2023/07/11/ncbi-datasets-genome-assembly-pages/&nbsp;<a href="https://ow.ly/GU3o50P8QH4"></a><a href="https://www.linkedin.com/feed/hashtag/?keywords=ncbicgr&amp;highlightedUpdateUrns=urn%3Ali%3Aactivity%3A7084592728260386816">#NCBICGR</a></p><p><span>Effective July 10, 2023, NCBI&rsquo;s Assembly and Genome record pages now redirect to&nbsp;</span>new<a href="https://www.ncbi.nlm.nih.gov/datasets/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=datasets-genome-assembly-redirect-20230711"> NCBI Datasets </a><span>pages. As&nbsp;</span><a href="https://ncbiinsights.ncbi.nlm.nih.gov/2023/03/07/ncbi-datasets-genome-taxonomy-pages/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=datasets-genome-assembly-redirect-20230711">previously announced</a><span>, these updates are part of our ongoing effort to modernize and improve your user experience. NCBI Datasets is a new resource that makes it easier to find and download genome data.  </span><span>&nbsp;</span></p><h5>The following pages have been updated:</h5><ul>
<li><span>The NCBI Assembly record pages now redirect to the new </span><a href="https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_023065955.2/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=datasets-genome-assembly-redirect-20230711"><span>NCBI Datasets</span><strong><span> </span></strong><span>Genome</span></a><span> </span><span>record pages that describe assembled genomes and provide links to related NCBI tools such as Genome Data Viewer and BLAST. </span><span>&nbsp;</span></li>
<li><span>The NCBI</span><strong> </strong><span>Genome record pages now redirect to the </span><a href="https://www.ncbi.nlm.nih.gov/datasets/taxonomy/9644/?utm_source=ncbi_insights&amp;utm_medium=referral&amp;utm_campaign=datasets-genome-assembly-redirect-20230711"><span>NCBI Datasets</span><strong><span> </span></strong><span>Taxonomy</span></a><span> </span><span>record pages that provide a taxonomy-focused portal to genes, genomes, and additional NCBI resources.  </span><span>&nbsp;</span></li>
</ul><p><span>During this transition, you will have the option to return to the legacy Genome and Assembly record pages. We will remove the legacy pages in early 2024. </span><span>&nbsp;</span></p>]]></description>
	<dc:creator>BioStar</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34744/foldit-solve-puzzles-for-science</guid>
	<pubDate>Thu, 21 Dec 2017 15:17:47 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34744/foldit-solve-puzzles-for-science</link>
	<title><![CDATA[Foldit: Solve Puzzles for Science]]></title>
	<description><![CDATA[<p><span>Foldit</span><span>&nbsp;is an online puzzle video game about protein&nbsp;</span><span>folding. It</span><span>&nbsp;is part of an experimental research project developed by the University of Washington, Center for Game Science, in collaboration with the UW Department of Biochemistry. The objective of&nbsp;</span><span>Foldit</span><span>&nbsp;is to&nbsp;</span><span>fold</span><span>&nbsp;the structures of selected proteins as perfectly as possible</span></p>
<p>https://fold.it/portal/</p><p>Address of the bookmark: <a href="https://fold.it/" rel="nofollow">https://fold.it/</a></p>]]></description>
	<dc:creator>Robert M Willioms</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/1471/24-mb-genome-size-for-worlds-biggest-virus</guid>
	<pubDate>Thu, 08 Aug 2013 10:05:37 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/1471/24-mb-genome-size-for-worlds-biggest-virus</link>
	<title><![CDATA[2.4 Mb Genome Size for World's Biggest Virus]]></title>
	<description><![CDATA[<p>The genome size of new discovered Pandoraviruses have roughly twice the size of the record-holding Megavirus genomic code. Interestingly only 6 percent of its genes resembled the genes other organisms. It is assume that it may come from a different origin.</p><p>For detail : http://www.sciencemag.org/content/341/6143/281</p><p>http://www.npr.org/blogs/health/2013/07/18/203298244/worlds-biggest-virus-may-have-ancient-roots</p><p>&nbsp;</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/5933/virus-3d-animation</guid>
	<pubDate>Sat, 26 Oct 2013 09:01:27 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/5933/virus-3d-animation</link>
	<title><![CDATA[Virus 3D Animation]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/67ays2ZYr48" frameborder="0" allowfullscreen></iframe>piranha.dl facebook site: http://www.facebook.com/home.php?#!/pages/piranhadl-3D/131721586891915]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/43940/langya-virus-update</guid>
	<pubDate>Fri, 12 Aug 2022 05:31:10 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/43940/langya-virus-update</link>
	<title><![CDATA[Langya Virus Update !]]></title>
	<description><![CDATA[<p>https://www.ncbi.nlm.nih.gov/nuccore/OM101125,OM101126,OM101127,OM101128,OM101129,OM101130?</p><p>Zoonotic Henipavirus</p><p>https://pubmed.ncbi.nlm.nih.gov/35921459/</p><p>https://www.ncbi.nlm.nih.gov/nuccore/OM069646,,OM069567,OM069568,OM069569,OM069570,OM069571,OM069572,OM069573,OM069574,OM069575,OM069576,OM069577,OM069578,OM069579,OM069580,OM069581,OM069582,OM069583,OM069584,OM069585,OM069586,OM069587,OM069588,OM069589,OM069590,OM069591,OM069592,OM069593,OM069594,OM069595,OM069596,OM069597,OM069598,OM069599,OM069600,OM069601,OM069602,OM069603,OM069604,OM069605,OM069606,OM069607,OM069608,OM069609,OM069610,OM069611,OM069612,OM069613,OM069614,OM069615,OM069616,OM069617,OM069618,OM069619,OM069620,OM069621,OM069622,OM069623,OM069624,OM069625,OM069626,OM069627,OM069628,OM069629,OM069630,OM069631,OM069632,OM069633,OM069634,OM069635,OM069636,OM069637,OM069638,OM069639,OM069640,OM069641,OM069642,OM069643,OM069644,OM069645,OM069646</p>]]></description>
	<dc:creator>Neel</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44628/uncovar-workflow-for-transparent-and-robust-virus-variant-calling-genome-reconstruction-and-lineage-assignment</guid>
	<pubDate>Mon, 05 Aug 2024 23:01:29 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44628/uncovar-workflow-for-transparent-and-robust-virus-variant-calling-genome-reconstruction-and-lineage-assignment</link>
	<title><![CDATA[UnCoVar: Workflow for Transparent and Robust Virus Variant Calling, Genome Reconstruction and Lineage Assignment]]></title>
	<description><![CDATA[<p>UnCoVar: Workflow for Transparent and Robust Virus Variant Calling, Genome Reconstruction and Lineage Assignment</p>
<ul>
<li>
<p>Using state of the art tools, easily extended for other viruses</p>
</li>
<li>
<p>Tool and database updates for critical components via Conda</p>
</li>
<li>
<p>Built using modern design patterns with Conda and Snakemake</p>
</li>
<li>
<p>Extensible and easy to customize</p>
</li>
<li>
<p>Submission Ready Genomes</p>
</li>
<li>
<p>Customizable reporting with comprehensive visualization</p>
</li>
</ul>
<p>https://ikim-essen.github.io/uncovar/</p>
<p>Github&nbsp;https://github.com/IKIM-Essen/uncovar</p>
<p>&nbsp;</p>
<p>&nbsp;</p><p>Address of the bookmark: <a href="https://ikim-essen.github.io/uncovar/" rel="nofollow">https://ikim-essen.github.io/uncovar/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/40789/complete-genome-sequence-of-wuhan-seafood-market-pneumonia-virus-is-out</guid>
	<pubDate>Fri, 31 Jan 2020 02:36:59 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/40789/complete-genome-sequence-of-wuhan-seafood-market-pneumonia-virus-is-out</link>
	<title><![CDATA[Complete genome sequence of Wuhan seafood market pneumonia virus is out !]]></title>
	<description><![CDATA[<p>Wuhan-Hu-1 claimed at least 40 lives and infected at least 1300 others in China. Cases are now being reported from Thailand, Singapore, Malaysia, South Korea, Japan, Vietnam, Nepal, France, Australia and even as far as the US.&nbsp;On Jan 10 2020, while news of the first fatality was barely trickling in, the <a href="https://www.ncbi.nlm.nih.gov/nuccore/MN908947">29,903 letters</a> constituting the viral genome from an affected individual in Wuhan had already been elucidated (even though a few corrections were made subsequently). All the viral genome sequences from affected individuals are very very close to each other. Several are identical and none has more than 5 differences (99.983% similarity). This strongly suggests that transmission into humans came from a single pointed source and happened very recently, between Sep-Dec 2019.</p><p>Check out the detail at https://www.ncbi.nlm.nih.gov/nuccore/MN908947</p>]]></description>
	<dc:creator>Jit</dc:creator>
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