https://www.nist.gov/news-events/news/2016/09/nist-releases-new-family-standardized-genomes

Address of the bookmark: https://jimb.stanford.edu/giab/

Address of the bookmark: https://github.com/CMU-SAFARI/SneakySnake

Please take a look at our FAQ section and do not hesitate to report bugs or suggestions for improvements by email.

Address of the bookmark: https://chlorobox.mpimp-golm.mpg.de/OGDraw.html

Address of the bookmark: https://github.com/martinjvickers/KAST

Address of the bookmark: https://genomes.atcc.org/

Here are few companies:

https://mynucleus.com/

https://myome.com/

https://nebula.org/whole-genome-sequencing-dna-test/

What Are piRNAs?

piRNAs are the largest class of small non-coding RNAs, typically 24–32 nucleotides in length. Unlike microRNAs (miRNAs) and small interfering RNAs (siRNAs), piRNAs do not rely on Dicer enzymes for maturation. Instead, they are processed from long single-stranded precursors and associate with PIWI proteins, a subclass of the Argonaute protein family.

The primary functions of piRNAs include:

1. Silencing Transposable Elements: By targeting transposons, piRNAs prevent genomic instability, particularly in germline cells.
2. Regulating Gene Expression: piRNAs modulate gene expression at transcriptional and post-transcriptional levels.
3. Epigenetic Modulation: They guide epigenetic modifications, such as DNA methylation, to specific genomic loci.

Challenges in piRNA Research

Studying piRNAs is fraught with challenges, including:

• Short Length: Their small size complicates sequencing and alignment.
• Lack of Sequence Conservation: Unlike miRNAs, piRNAs exhibit limited sequence conservation across species.
• Complex Biogenesis: The intricate pathways of piRNA generation require sophisticated computational tools to unravel.

Bioinformatics: Illuminating the World of piRNAs

Bioinformatics has emerged as an indispensable tool for studying piRNAs, facilitating their discovery, annotation, and functional analysis. Here's how bioinformatics is transforming piRNA research:

1. Identification and Annotation

The discovery of piRNAs relies on next-generation sequencing (NGS) data. Bioinformatics tools such as piRNApredictor and Piano identify piRNA clusters and predict potential targets. Databases like piRBase and piRNAdb curate information about known piRNAs, their sequences, and associated proteins.

2. Mapping and Alignment

piRNAs often originate from repetitive regions, making their alignment challenging. Tools like Bowtie and STAR handle the unique mapping requirements of piRNAs, enabling accurate identification of piRNA clusters in genomes.

3. Functional Analysis

Bioinformatics approaches predict piRNA functions by analyzing their interactions with transposons, genes, and epigenetic marks. Algorithms such as TargetFinder and RIblast explore piRNA-mRNA interactions, shedding light on regulatory networks.

4. Evolutionary Studies

piRNAs are evolutionarily diverse, reflecting their roles in species-specific genomic defense. Comparative genomics tools help trace the evolution of piRNA clusters and their associated PIWI proteins across species.

5. Epigenomic Insights

piRNAs are key players in epigenetic regulation. Bioinformatics pipelines integrate piRNA data with chromatin immunoprecipitation sequencing (ChIP-seq) and DNA methylation data to uncover their role in shaping the epigenome.

Case Study: piRNAs in Germline Integrity

One of the hallmark functions of piRNAs is the suppression of transposable elements in the germline. For example, in Drosophila melanogaster, piRNAs target retrotransposons like gypsy and copia. Bioinformatics analyses revealed that these piRNAs guide PIWI proteins to transposon-derived RNA, ensuring genome stability during gametogenesis.

Clinical Relevance of piRNAs

Recent studies suggest that piRNAs may serve as biomarkers for diseases such as cancer, infertility, and neurodegenerative disorders. For instance:

• Cancer: Dysregulated piRNA expression has been linked to tumorigenesis, making them potential targets for cancer therapies.
• Infertility: Aberrant piRNA pathways are implicated in male infertility due to their role in spermatogenesis.
• Neurodegeneration: piRNAs may regulate neuronal gene expression, highlighting their potential in neurological research.

Future Directions

The integration of bioinformatics with emerging technologies offers exciting opportunities for piRNA research:

• Single-Cell Sequencing: Unveiling cell-specific piRNA expression and function.
• Machine Learning: Predicting piRNA functions and targets with greater accuracy.
• CRISPR-Based Tools: Editing piRNA clusters to explore their roles in vivo.

Conclusion

piRNAs are the unsung guardians of the genome, safeguarding genetic material from transposable elements and contributing to gene regulation and epigenetic programming. Bioinformatics has opened the floodgates of discovery, unraveling the complexities of piRNAs and their myriad roles in biology and disease.

As we continue to decode the piRNA landscape, these small RNAs promise to unveil big secrets about genome stability, evolution, and human health, cementing their place as a fascinating frontier in molecular biology.

Key Findings:

1. Chromosomal Fusion and Its Molecular Signature:

   • The fusion site is located at 2q13–2q14.1 and is characterized by degenerate telomeric sequences appearing interstitially, indicating the historical head-to-head joining of ancestral chromosomes.
   • Despite being a signature of a past fusion event, these telomeric repeats are no longer functional and have undergone sequence degradation over time.

2. Extensive Duplications in the Surrounding Genomic Region:

   • The study identifies large-scale segmental duplications flanking the fusion site, with several of these regions duplicated and scattered across multiple chromosomes.
   • These duplications are predominantly located in subtelomeric and pericentromeric regions, suggesting their role in genomic instability and chromosomal evolution.

3. Paralogous Regions and Their Evolutionary Relationships:

   • A 168-kilobase (kb) segment near the fusion site has 98%–99% sequence identity with three regions on chromosome 9 (9pter, 9p11.2, and 9q13).
   • Another 67-kb region distal to the fusion site shows a high degree of homology to sequences in chromosome 22qter.
   • Additionally, a 100-kb segment exhibits 96% sequence identity with a region in chromosome 2q11.2.

4. Comparative Genomics and Evolutionary Implications:

   • By comparing the duplicated sequences and their arrangement in primates, the researchers traced the order of duplication events leading to their present distribution.
   • The presence of specific repetitive elements within these duplicated segments serves as evolutionary markers that help infer their historical rearrangements.
   • Some of these duplicated regions are associated with chromosomal inversion breakpoints, potentially contributing to evolutionary changes in primates.
   • Recurrent structural rearrangements in these regions have been linked to human chromosomal disorders.

Conclusions and Implications:

• The findings provide valuable insights into the structural evolution of human chromosome 2, which played a crucial role in human speciation.
• Understanding these segmental duplications and their evolutionary trajectories sheds light on genomic instability, which may contribute to human genetic diseases.
• The study highlights how large-scale chromosomal rearrangements, such as fusion and duplication, have influenced the evolutionary divergence of humans from other primates.

This research advances our understanding of human genome evolution and offers a foundation for studying the effects of structural variants in genetic disorders.

The aims of bio/medical research are also broad, including:
• Understanding mechanism of disease
• Understanding the impact of genetic and external factors on human health
• Designing and evaluating new therapeutic interventions
• Health genomics

List of Research Institutes in India (Biological Sciences)

BANGALORE
Ashoka Trust for Ecology and the Environment
Royal Enclave, Srirampura, Jakkur Post, Bangalore-560064
Email: info@atree.org
Web: www.atree.org/
Research: ATREE deals with issues relating to the environmental, social and economic dimensions, and implications of, biological resources and natural ecosystems

Indian Institute of Science
Indian Institute of Science, Bangalore 560 012, Karnataka
Email:regr@admin.iisc.ernet.in
Web: www.iisc.ernet.in/
Research Areas: Biochemistry, ecological sciences, microbiology & cell biology, molecular biophysics, molecular reproduction, development & genetics.

Jawaharlal Nehru Centre for Advanced Scientific Research
Jakkur, Bangalore 560 064, Karnataka
Email: academic@jncasr.ac.in
Web: www.jncasr.ac.in/
Research Areas: Evolutionary and organismal biology, molecular biology and genetics.

National Centre for Biological Science
GKVK, Bellary Road,
Email: dean@ncbs.res.in
Web: www.ncbs.res.in
Research Areas: The research interests of the faculty range from single molecules to systems biology.

National Institute of Mental Health and Neurosciences
Bangalore 560029, Karnataka
Email: info@nimhans.kar.nic.in
Web: nimhans.kar.nic.in/
Research Areas: Biophysics, biostatistics, clinical psychology, epidemiology, human genetics, mental health education, neuroanaesthesia, neurochemistry, neuro imaging and interventional radiology, neurology, neuromicrobiology, neuropathology, neurophysiology, neurosurgery, neurovirology.

Stem Cell Institute
NCBS, GKVK, Bellary Road,
Email: ramas@ncbs.res.in
Web: underconstruction

University of Agricultural Sciences
GKVK, Bangalore 5600065, Karnataka
Email: root@uas.kar.nic.in
Web: uasbng.kar.nic.in/Default.htm
BARODA

Maharaja Sayajirao University of Baroda
Fatehgunj, Vadodara 390 002, Gujarat
Web: msubaroda.ac.in/

BHOPAL
Indian Institute of Science Education and Research–Bhopal
Govindpura, Bhopal - 23
E-mail: director@iiserbhopal.ac.in
Web: www.iiserbhopal.ac.in/
Research Areas: All areas of basic sciences – Biology, chemistry, math and physics
BHUBANESHWAR
Institute of Life Sciences
Bhubaneswar 751 023, Orissa
Web: www.ils.res.in
Research Areas: Cancer, malaria, age diseases, stress biology, ecophysiology, plant molecular physiology, filariasis, tuberculosis, bio-perspecitve, agricultural biotechnology, bio-informatics.

National Institute of Science Education and Research – Bhubaneshwar
Institute of Physics Campus, Bhubaneswar, Orissa - 751 005,
e-mail : director@niser.ac.in
Web: www.niser.ac.in/
Research Areas: All areas of basic sciences – Biology, chemistry, math and physics.

Regional Research Laboratory
Bhubaneswar 751 013, Orissa
Email: root@csrrlbhu.ren.nic.in
Web: www.icast.org.in/csir/rrl_bhu.html
Research Areas: Survey & cultivation of aromatic, medicinal and other economic plants.

Utkal University
Vani Vihar, Bhubaneswar 751 004, Orissa
Web: www.utkaluniversity.org/
CHANDIGARH
Indian Institute of Science Education and Research –Mohali
Chandigarh
Email: webmaster@iisermohali.ac.in
Web: www.iisermohali.ac.in/
Research Areas: All areas of basic sciences – Biology,
chemistry, math and physics

Institute of Microbial Technology
Sector 39–A, Chandigarh 160 036
Email: raghava@imtech.res.in
Web: www.imtech.res.in/
Research Areas: Molecular biology and microbial genetics,
animal cell/tissue culture and protein engineering.

Panjab University
Chandigarh 160 014
Email: pulib@puchd.ren.nic.in
Web: www.puchd.ac.in/

Postgraduate institute of Medical Education and Research
Sector-12, Chandigarh, 160 012
Email: pgimer@chd.nic.in
Web: pgimer.nic.in/
Research Areas: Obstetrics and gynaecology, psychiatry,
biochemistry, haematology, clinical parasitology etc.
CHENNAI
Indian Institute of Technology Madras
Chennai 600 036, Tamil Nadu
Email: tppro@acer.iitm.ernet.in
Web: www.iitm.ac.in
Research Areas: Engineering: Biotechnology.

University of Madras
University Centenary Building, Chepauk, Chennai 600 005, Tamil Nadu
Email: webmaster@unom.ac.in
Web: www.unom.ac.in/
DARJEELING
University of North Bengal
Raja Rammohunpur, Darjeeling 734 430, West Bengal
Email:(Registrar): regnbu@dte.vsnl.net.in
Web: www.nbu.ac.in/
DELHI
All India Institute of Medical Sciences
New Delhi
Email: webmastr@aiims.ac.in
Web: www.aiims.ac.in/

Institute of Genomics and Integrative Biology
Delhi University Campus, Mall Road, Delhi 110 007
Email: info@igib.res.in
Web: www.igib.res.in/
Research Areas: Allergy and immunology, diagnostics, genetic engineering, bio-organics and high-tech reagents.

Indian Institute of Technology Delhi
Hauz Khas, New Delhi 110 016
Email: malhotra@admin.iitd.ernet.in
Web: www.iitd.ac.in
Research Areas: Engineering: Biochemical engineering & biotechnology.
International Centre for Genetic Engineering and Biotechnology

ICGEB Campus, Aruna Asaf Ali Marg,
New Delhi 110 067
Web: www.icgeb.trieste.it/
Research Areas: Mammalian biology:
Virology immunology, malaria,
recombinant gene products,
Plant molecular biology, plant transformation,
insect resistance, plant resistance.

Jawaharlal Nehru University
New Delhi
Email: webmaster@mail.jnu.ac.in
Web: www.jnu.ac.in

National Centre for Plant Genome Research
JNU Campus, New Delhi
Email: tapas_s3@yahoo.co.in
Web: ncpgr.nic.in/
Research Areas: Nutritional, structural, and functional genomics of various plant systems.

National Institute of Immunology
Aruna Asaf Ali Marg, New Delhi 110 067
Web: www.nii.res.in/
Research Areas: Gene regulation, immunity & infection, molecular design, reproduction & development.

TERI University
Vasant Kunj, New Delhi - 110 070 / India
E-mail: registrar@teri.res.in
Web: www.teriuniversity.ac.in
Research Areas: Environmental Studies, Natural Resources Management, Climate Science and Policy, Plant Biotechnology

University of Delhi
University Road, Delhi 110 007
Email: webmaster@du.ac.in
Web: www.du.ac.in/
GOA
National Centre for Antarctic and Ocean Research
Headland Sada, Vasco-da-Gama 403 804, Goa
Email: info@ncaor.org
Research Areas: Co–ordination and implementation of the Indian Antarctic Programme.


National Institute of Oceanography
Dona Paula 403 004, Goa
Email: webmaster@darya.nio.org
Web: www.nio.org/
Research Areas: International geosphere-bio-sphere programme, marine biotechnology.
GURGAON
National Brain Research Centre
Near NSG Campus, Nainwal Mode, Manesar, Gurgaon, Haryana
Email: info@nbrc.ac.in
Web: www.nbrc.ac.in/
Research Areas: Brain research.
GUWAHATI
Indian Institute of Technology Guwahati
North Guwahati, Guwahati 781 039, Assam
Email: mcb@iitg.ernet.in
Web: www.iitg.ernet.in
Research Areas: Engineering: Biotechnology.


Gauhati University
Gopinath Bordoloi Nagar, Guwahati 781 014, Assam
Web: http://www.gauhati.ac.in/.
HYDERABAD
Centre for Cellular & Molecular Biology
Uppal Road, Hyderabad 500 007, Andhra Pradesh
Email: (Director): lalji@ccmb.res.in
Web: www.ccmb.res.in/
Research Areas: Biophysics & biochemistry, molecular biology, genetics & evolution, biomedicines & biotechnology.


Centre for DNA Fingerprinting and Diagnostics
CDFD, Bldg. 7, Gruhakalpa, 5-4-399/B, Nampally, Hyderabad - 500 001.
Email: director@cdfd.org.in
Web: www.cdfd.org.in/
Research Areas: Automated genome analysis, bacterial genetics, cancer biology, cell biology & gene expression, computational biology, computational & functional genomics, immunology, mammalian genetics, molecular genetics, molecular oncology, molecular virology, structural biology, transcription, developmental neuroscience and drosophila genetics.


Indian Institute of Chemical Technology
Uppal Road, Hyderabad 500 007, Andhra Pradesh
Email: kvr@iict.ap.nic.in, sampath@iict.ap.nic.in
Web: www.iictindia.org/
Research Areas: Pesticides, drugs, organic intermediates and fine chemicals.


LV Prasad Eye Intstitute
Hyderabad, Andhra Pradesh, India
Email: communications@lvpei.org
Web: www.lvpei.org/
LVPEI is a World Health Organization Collaborating Center for Prevention of Blindness. Equipped with cutting-edge technology and distinguished professionals in the field of Eye care


University of Hyderabad
P.O. Central University, Gachibowli, Hyderabad 500 046, Andhra Pradesh
Email: trctcs@uohyd.ernet.in
Web: www.uohyd.ernet.in/
IMPHAL
Institute of Bioresources and Sustainable Development
Takyelpat, Imphal 795 001, Manipur
Email: ibsd_imp@sancharnet.in, ibsd-imphal@man.nic.in
Web: ibsd-imphal.nic.in/
Research Areas: Conservation of biodiversity and sustainable utilisation of biodiversity.
ITANAGAR
North Eastern Regional Institute of Science and Technology
Itanagar, Nirjuli, Papumpare 791 109, Arunachal Pradesh
Email: dir@nerist.ernet.in
Web: www.nerist.ac.in/
Research Areas: Agricultural engineering, forestry.
JAIPUR
University of Rajasthan
Jaipur 320 004, Rajasthan
Email: info@uniraj.org
Web: www.uniraj.org/
JAMMU and KASHMIR
Regional Research Laboratory
Canal Road, Jammu 130 001, Jammu & Kashmir
Email: (Director): qazi_gn@yahoo.com, root@csrrljm.ren.nic.in
Web: www.rrljammu.org/
Research Areas: Natural products & organic chemistry, improvement & cultivation of medicinal and aromatic plants, post harvest technology and applied microbiology & mutation genetics.

University of Jammu
Jammu 180 006, Jammu & Kashmir
Web: www.jammuuniversity.org/

University of Kashmir
Hazratbal,Srinagar-190006,Jammu and Kashmir
Email: info@kashmiruniversity.net
Web: http://www.kashmiruniversity.net/

Sher-i-Kashmir Institute of Medical Science (SKIMS)
Srinagar, Jammu and Kashmir
Email: skimsweb@gmail.com
Web: http://www.skims.ac.in/

Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST)
Shalimar Campus, Srinagar - 191121 Jammu and Kashmir
Email: skuastkashmir@gmail.com
Web: http://www.skuastkashmir.ac.in/
Research Areas: Agricultural Sciences, fisheries and veterinary sciences.
JORHAT
Regional Research Laboratory
Jorhat 785 006, Assam
Email: drrljt@csir.res.in, inform@csir.res.in
Web: jorhat.nic.in/rrl.htm
Research Areas: Agrochemicals, drugs and drug intermediates, organic chemistry, biochemistry.
KANPUR
Indian Institute of Technology Kanpur
GT Road, Kalyanpur, Kanpur 208 016, Uttar Pradesh
Email: infocell@iitk.ac.in
Web: www.iitk.ac.in/
Research Areas: Engineering: Biological sciences & bioengineering.
KHARAGPUR
Indian Institute of Technology Kharagpur
Kharagpur 721 302, West Bengal
Email: (PRO): ashok@hijli.iitkgp.ernet.in
Web: www.iitkgp.ernet.in/
Research Areas: Engineering: Biotechnology.
KOCHI
Cochin University of Science and Technology
South Kalamessery, Kochi 682 022, Kerala
Email: webmaster@cusat.ac.in
Web: www.cusat.ac.in/.
KOLKATA
Bose Institute
93/1, Acharya Prafulla Chandra Road, Kolkata 700 009, West Bengal
Email: sidroy@bic.boseinst.ernet.in
Web: www.boseinstitute.org/
Research Areas: Bioinformatics & computational biology, structure and functional dynamics of biomolecules, drug modeling, molecular genetics of microbes, transgenic plants etc.


Indian Institute of Chemical Biology
4, Raja S.C. Mullick Road, Jadavpur, Kolkata 700 032, West Bengal
Email: (Director): director@iicb.res.in
Web: www.iicb.res.in/
Research Areas: Natural products of medicinal, biological and industrial value, immunoassay techniques, tissue-targeted drug-delivery system.


Indian Institute of Science Education and Research –Kolkata
Mohanpur, Nadia, West Bengal
Web: www.iiserkol.ac.in/
Research Areas: All areas of basic sciences – Biology, chemistry, math and physics


Indian Statistical Institute, Kolkata
203 Barrackpore Trunk Road, Kolkata 700 108, West Bengal
Email: postmaster@isical.ac.in
Web: www.isical.ac.in/
Research Areas: Agricultural and ecological research, biological anthropology, human genetics.


Jadavpur University
188 Raja S.C. Mallik Road, Kolkata 700 032, West Bengal
Email: registrar@jdvu.ac.in
Web: www.jadavpur.edu/


University of Calcutta
Kolkata 700 009, West Bengal
Web: www.kolkata.org/cu/
KURUKSHETRA
Kurukshetra University
Kurukshetra 136 119, Haryana
Email: jskadian@rediffmail.com
Web: kuk.ernet.in/
LUCKNOW
Birbal Sahni Institute of Palaeobotany
53 University Road, Lucknow, Uttar Pradesh
Email: director@bsip.res.in
Web: www.bsip-india.org/index.htm
Research Areas: Botanical palaeobotany: Morphotaxonomy, palaeoecology, palaeogeography, phylogeny and evolution.


Central Drug Research Institute
Chattar Manzil Palace, Post Box No. 173, Lucknow 226 001, Uttar Pradesh
Email: info@cdriindia.org
Web: www.cdriindia.org/
Research Areas: Development of contraceptives, new drugs for tropical diseases (malaria, filariasis, leishmaniasis), cardio-vascular and central nervous system disorders.


Indian Institute of Science Education and Research –Kolkata
Mohanpur, Nadia, West Bengal
Web: www.iiserkol.ac.in/
Research Areas: All areas of basic sciences – Biology, chemistry, math and physics


Indian Statistical Institute, Kolkata
203 Barrackpore Trunk Road, Kolkata 700 108, West Bengal
Email: postmaster@isical.ac.in
Web: www.isical.ac.in/
Research Areas: Agricultural and ecological research, biological anthropology, human genetics.


Central Institute of Medicinal and Aromatic Plants
Lucknow 226 015, Uttar Pradesh
Email: director@cimap.res.in
Web: www.cimap.res.in/
Research Areas: Agrotechnologies for medicinal and aromatic plants, phytochemistry, plant physiology and biochemistry, pathology, genetics, entomology and pharmacognosy.


Industrial Toxicology Research Centre
Mahatma Gandhi Marg, P.O. Box No. 80, Lucknow 226 001, Uttar Pradesh
Email: info@itrcindia.org
Web: www.itrcindia.org/
Research Areas: Neurotoxicology, environmental health, immunotoxicology and environmental biotechnology.


National Botanical Research Institute
Rana Pratap Marg, Lucknow 226 001, Uttar Pradesh
Email: p.pushpangadan@nbri.res.in
Web: www.nbri-lko.org/
Research Areas: Plant biotechnology, environmental sciences, taxonomy and ethnobotany, plant molecular biology.
MUMBAI
Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)
Tata Memorial Centre, Navi Mumbai - 410 210
Web: www.actrec.gov.in/
Research Areas: Research investigations currently focus on molecular mechanisms of cancer, drug development and emerging therapies for treatment and prevention of cancer.


Bhabha Atomic Research Centre
Trombay, Mumbai 400 085, Maharashtra
Email: webmaster@magnum.barc.ernet.in
Web: www.barc.ernet.in/
Research Areas: Chemical and life sciences, nuclear agriculture.


Bombay Natural History Society
Hornbill House, Shaheed Bhagat Singh Road, Mumbai 400 023, Maharashtra
Email: bnhs@bom4.vsnl.net.in
Web: www.bnhs.org/


Indian Institute of Technology Bombay
Powai, Mumbai 400 076, Maharashtra
Email: registrar@iitb.ac.in
Web: www.iitb.ac.in/
Research Areas: Earth sciences; Science: Biology, chemistry, mathematics, physics.


Tata Institute of Fundamental Research
Homi Bhabha Road, Navy Nagar, Colaba, Mumbai 400 005.
Web: www.tifr.res.in/
Department of Biological Sciences: www.tifr.res.in/~dbs
Research Areas: TIFR is a multidisciplinary research organisation working in the area of Natural Sciences (Biology, Chemistry, and Physics), Mathematics and Computer Science.


University of Mumbai
Vidyanagari, Kalina, Santa Cruz (W), Mumbai 400 098, Maharashtra
Web: www.mu.ac.in/


National Botanical Research Institute
Rana Pratap Marg, Lucknow 226 001, Uttar Pradesh
Email: p.pushpangadan@nbri.res.in
Web: www.nbri-lko.org/
Research Areas: Plant biotechnology, environmental sciences, taxonomy and ethnobotany, plant molecular biology.
NAGPUR
National Environmental Engineering Research Institute
Nehru Marg, Nagpur 440 020, Maharashtra
Email: dirneeri@nagpur.dot.net.in
Web: www.neeri.nic.in/
Research Areas: Environmental biotechnology.
PUNE
Agharkar Research Institute
G.G. Agarkar Road, Pune 411 004, Maharashtra
Web: www.aripune.org/
Research Areas: Animal sciences, microbial sciences, plant sciences.


Indian Institute of Science Education and Research–Pune
Email: director@iiserpune.ac.in
Web: www.iiserpune.ac.in/
Research Areas: All areas of basic sciences – Biology, chemistry, math and physics.


National Chemical Laboratory
Dr. Homi Bhabha Road, Pune 411 008, Maharashtra
Email: director@ems.ncl.res.in
Web: www.ncl-india.org/
Research Areas: biotechnology, biochemistry.>


National Centre for Cell Sciences
NCCS Complex, Ganeshkhind, Pune 411 007, Maharashtra
Email: infonccs@giaspn01.vsnl.net.in
Web: www.nccs.res.in/
Research Areas: Cell biology, molecular biology, immunology, parasitology, hybridoma technology, tissue banking & tissue engineering, regenerative biology, virology (HIV), cancer biology, diabetes, cryobiology transplantation, gene therapy.


University of Pune
Ganeshkhind Road, Pune 411 007, Maharashtra Telephone: 020-5601305
Email: Registrar): regis@unipune.ernet.in
Web: www.unipune.ernet.in/
PALAMPUR
Institute of Himalayan Bioresource Technology
Post Box No. 6, Palampur 176 061, Himachal Pradesh
Email: root@csihbt.ren.nic.in, director@ihbt.csir.res.in
Web: www.icast.org.in/csir/ihbt.html
Research Areas: Floriculture, tea sciences, biotechnology and natural plant products.
PATIALA
Punjabi University
Patiala 147 002, Punjab
Email: ucc@pbi.ac.in
Web: www.universitypunjabi.org/
PILANI
Birla Institute of Technology and Science
Vidhya Vihar Campus, Pilani, 333 031, Rajasthan
Email: mmsanand@bits-pilani.ac.in
Web: www.bits-pilani.ac.in/
ROORKEE
Indian Institute of Technology Roorkee
Roorkee 247 667, Uttaranchal
Email: (Registrar): regis@iitr.ernet.in
Web: www.iitr.ernet.in/
Research Areas: Engineering: Biotechnology.
SHANTINIKETAN
Visva-Bharati University
Santiniketan, Birbhum 731 235, West Bengal
Email: Root@vbharat.ernet.in
Web: www.visva-bharati.ac.in/
SHILLONG
North-Eastern Hill University
Umshing, Shillong 793 022, Meghalaya
Email: admin@nehu.ac.in
Web: www.nehu.ac.in/
SILCHAR
Assam University
P.O. Box 63, Silchar 788 011, Assam
Email: auliba@sancharnet.in, asokesen@sancharnet.in
Web: assamuniversity.nic.in/
TRIVANDUM
Indian Institute of Science Education and Research–Trivandum
Trivandrum, Kerala,India.
Web: www.iisertvm.ac.in/
Research Areas: All areas of basic sciences – Biology, chemistry, math and physics


Rajiv Gandhi Centre for Biotechnology
Thycaud P.O., Thiruvananthapuram 695 , Kerala
Email: info@rgcb.res.in
Web: rgcb.res.in/
Research Areas: Disease biology and molecular medicine, Plant biotechnology


Regional Research Laboratory
Industrial Estate P.O., Pappanamcode, Thiruvananthapuram 695 019, Kerala
Email: root@csrrltrd.ren.nic.in
Web: w3rrlt.csir.res.in/
Research Areas: Chemistry of natural products, agroprocessing, photochemical systems including solar energy conversion, analysis of pollutants and waste-water technology.

VARANASI
Banaras Hindu University
Varanasi 221 005, Uttar Pradesh
Email: webmaster@bhu.ac.in
Web: www.bhu.ac.in/index.html

Rajiv Gandhi Centre for Biotechnology
Thycaud P.O., Thiruvananthapuram 695 , Kerala
Email: info@rgcb.res.in
Web: rgcb.res.in/
Research Areas: Disease biology and molecular medicine, Plant biotechnology


Indian Council for Agricultural Research
Main Web site: www.icar.org.in/
Research Institutes under ICAR: www.icar.org.in/icar15.html


CSIR Laboratories
Main CSIR website–www.csir.res.in/

-------------------------------

Department of Atomic Energy
Main CSIR website–www.barc.ernet.in/


Department of Biotechnology
Main CSIR website–dbtindia.nic.in/index.asp

Dept. of Science & Technology
Main Website: Main Website: www.dst.gov.in/


Indian Council for Medical Research
Main Web site: icmr.nic.in/
Research Institutes under ICMR: icmr.nic.in/institute.htm#Permanent%20Institutes/Centres

Ministry of Environment and Forest
Main Web site: envfor.nic.in/
Research Institutes under ICAR: cyberjournalist.org.in/linksr.html

More at https://software.broadinstitute.org/gatk/download/bundle

ftp://ftp.ncbi.nlm.nih.gov/snp/organisms/human_9606/VCF/GATK/.

ftp://ftp.broadinstitute.org/bundle/hg38/hg38bundle/

Address of the bookmark: https://console.cloud.google.com/storage/browser/genomics-public-data/resources/broad/hg38/v0?pli=1