<![CDATA[BOL: Related items]]> https://bioinformaticsonline.com/related/3917?offset=290 https://bioinformaticsonline.com/bookmarks/view/44537/the-atcc-genome-portal Wed, 15 May 2024 14:24:16 -0500 https://bioinformaticsonline.com/bookmarks/view/44537/the-atcc-genome-portal <![CDATA[The ATCC Genome Portal]]> The ATCC Genome Portal (AGP, https://genomes.atcc.org/) is a database of authenticated genomes for bacteria, fungi, protists, and viruses held in ATCC’s biorepository. It now includes 3,938 assemblies (253% increase) produced under ISO 9000 by ATCC. Here, we present new features and content added to the AGP for the research community.

Address of the bookmark: https://genomes.atcc.org/

]]> Abhi https://bioinformaticsonline.com/bookmarks/view/44489/proksee Wed, 27 Mar 2024 11:11:54 -0500 https://bioinformaticsonline.com/bookmarks/view/44489/proksee <![CDATA[Proksee]]> Proksee is an expert system for genome assembly, annotation and visualization. To begin using Proksee, provide a complete genome sequence, sequencing reads or a CGView/Proksee map JSON file.

Please Cite the Following
Grant JR, Enns E, Marinier E, Mandal A, Herman EK, Chen C, Graham M, Van Domselaar G, and Stothard P
Nucleic Acids Research, 2023, gkad326, https://doi.org/10.1093/nar/gkad326

Address of the bookmark: https://proksee.ca/

]]> LEGE https://bioinformaticsonline.com/bookmarks/view/44628/uncovar-workflow-for-transparent-and-robust-virus-variant-calling-genome-reconstruction-and-lineage-assignment Mon, 05 Aug 2024 23:01:29 -0500 https://bioinformaticsonline.com/bookmarks/view/44628/uncovar-workflow-for-transparent-and-robust-virus-variant-calling-genome-reconstruction-and-lineage-assignment <![CDATA[UnCoVar: Workflow for Transparent and Robust Virus Variant Calling, Genome Reconstruction and Lineage Assignment]]> UnCoVar: Workflow for Transparent and Robust Virus Variant Calling, Genome Reconstruction and Lineage Assignment

  • Using state of the art tools, easily extended for other viruses

  • Tool and database updates for critical components via Conda

  • Built using modern design patterns with Conda and Snakemake

  • Extensible and easy to customize

  • Submission Ready Genomes

  • Customizable reporting with comprehensive visualization

https://ikim-essen.github.io/uncovar/

Github https://github.com/IKIM-Essen/uncovar

 

 

Address of the bookmark: https://ikim-essen.github.io/uncovar/

]]> BioStar https://bioinformaticsonline.com/blog/view/44754/early-genome-screening-the-new-health-horoscope Thu, 02 Jan 2025 19:44:36 -0600 https://bioinformaticsonline.com/blog/view/44754/early-genome-screening-the-new-health-horoscope <![CDATA[Early Genome Screening: The New Health Horoscope!]]> In an era where precision medicine is reshaping healthcare, genome screening is emerging as the modern equivalent of a health horoscope. It offers insights into our biological "stars," unraveling predispositions to various conditions and empowering individuals with knowledge to navigate their health journeys proactively. But how reliable is this "horoscope," and how does it impact our lives?

Understanding Genome Screening

Genome screening involves analyzing an individual's DNA to identify genetic variations that may influence health and disease susceptibility. This can range from simple single-gene tests to comprehensive whole-genome sequencing. By peering into our genetic blueprint, we can uncover risks for conditions like cancer, diabetes, cardiovascular diseases, and even rare genetic disorders.

The process is straightforward: a saliva or blood sample is collected, and advanced sequencing technologies decipher the genetic code. The results provide a personalized health map, guiding lifestyle modifications, preventive measures, or medical interventions.

A Shift from Reactive to Proactive Healthcare

Traditional healthcare often focuses on treating diseases after they manifest. Genome screening flips this model on its head, enabling a shift toward prevention and early intervention. For instance:

  • Cancer Risk Management: Individuals with BRCA1 or BRCA2 gene mutations can opt for enhanced screening programs or preventive surgeries to mitigate their risk of breast and ovarian cancers.

  • Cardiovascular Health: Genetic predispositions to conditions like familial hypercholesterolemia can prompt early cholesterol monitoring and lifestyle adjustments.

  • Rare Diseases: Identifying carriers of genetic disorders can aid in family planning and reduce the incidence of inherited conditions.

The Ethical and Practical Concerns

While genome screening offers incredible promise, it is not without challenges:

  1. Accuracy and Interpretation: Genetic predisposition does not guarantee disease. Misinterpretation of results can lead to unnecessary anxiety or unwarranted medical interventions.

  2. Privacy and Data Security: Genetic data is highly sensitive. Ensuring robust data protection measures is crucial to prevent misuse.

  3. Accessibility and Equity: High costs and limited availability may restrict access to genome screening, exacerbating health disparities.

Balancing Science and Pseudoscience

The comparison of genome screening to horoscopes isn’t entirely unfounded. Both offer predictive insights, but the scientific foundation of genome screening distinguishes it from astrology. Unlike the alignment of celestial bodies, genetic predictions are based on rigorous data and evidence. However, the probabilistic nature of genetic predispositions underscores the importance of interpreting results in conjunction with clinical and lifestyle factors.

The Road Ahead

As genome screening becomes more affordable and integrated into routine healthcare, its potential to transform lives is immense. Policymakers, healthcare providers, and genetic counselors must collaborate to ensure ethical implementation, public awareness, and equitable access.

Imagine a future where your genetic "horoscope" is a trusted guide, not just a prediction. Early genome screening could help chart a healthier path for generations, making it a cornerstone of personalized medicine. After all, our genes might just hold the key to unlocking a future of better health and well-being.

 

]]> LEGE https://bioinformaticsonline.com/bookmarks/view/44902/hite-a-fast-and-accurate-dynamic-boundary-adjustment-approach-for-full-length-transposable-elements-detection-and-annotation-in-genome-assemblies Sat, 20 Sep 2025 09:34:04 -0500 https://bioinformaticsonline.com/bookmarks/view/44902/hite-a-fast-and-accurate-dynamic-boundary-adjustment-approach-for-full-length-transposable-elements-detection-and-annotation-in-genome-assemblies <![CDATA[HiTE: a fast and accurate dynamic boundary adjustment approach for full-length Transposable Elements detection and annotation in Genome Assemblies]]> HiTE is a Python software that uses a dynamic boundary adjustment approach to detect and annotate full-length Transposable Elements in Genome Assemblies. In comparison to other tools, HiTE demonstrates superior performance in detecting a greater number of full-length TEs.

panHiTE

We have developed panHiTE, a comprehensive and accurate pipeline for TE detection in large-scale population genomes. It has been successfully applied to hundreds of plant population genomes, demonstrating its effectiveness and scalability.

For detailed instructions, please refer to the panHiTE tutorial.

Address of the bookmark: https://github.com/CSU-KangHu/HiTE

]]> LEGE https://bioinformaticsonline.com/videolist/watch/4763/inner-life-of-a-cell-full-versionmkv Mon, 23 Sep 2013 18:09:41 -0500 https://bioinformaticsonline.com/videolist/watch/4763/inner-life-of-a-cell-full-versionmkv <![CDATA[Inner Life Of A Cell - Full Version.mkv]]> Работа аппарата Гольджи и ЭПС при дифференцировке лейкоцита]]> https://bioinformaticsonline.com/videolist/watch/5582/the-human-microbiome-and-what-we-do-to-it Mon, 14 Oct 2013 16:25:10 -0500 https://bioinformaticsonline.com/videolist/watch/5582/the-human-microbiome-and-what-we-do-to-it <![CDATA[The human microbiome and what we do to it]]>

Did you know that you and I are only 1% human — we've 90 trillion cells which don't belong to us. Yes we are more bacteria than human. Have you ever wondered what it means to be human? It turns out that only a tiny percentage of what you and I are made of is actually human — and we need our non-human bits to survive. This part of us now has a name — it's called our microbiome. But we're doing dreadful things to this hidden majority and it's damaging our health as a result. From the Tonic series produced with the assistance of NPS. For more information visit: http://www.nps.org.au

]]> https://bioinformaticsonline.com/videolist/watch/9298/immunology-in-the-gut-mucosa Mon, 17 Mar 2014 11:10:29 -0500 https://bioinformaticsonline.com/videolist/watch/9298/immunology-in-the-gut-mucosa <![CDATA[Immunology in the Gut Mucosa]]> The gut mucosa hosts the body's largest population of immune cells. Nature Immunology in collaboration with Arkitek Studios have produced an animation unravelling the complexities of mucosal immunology in health and disease. Nature Immunology homepage: http://www.nature.com/ni/index.html Nature has full responsibility for all editorial content, including NatureVideo content. This content is editorially independent of sponsors.]]> https://bioinformaticsonline.com/fun/view/14036/introduction-to-programming-write-short-programs-that-generate-graphics-and-animation Thu, 14 Aug 2014 23:29:04 -0500 https://bioinformaticsonline.com/fun/view/14036/introduction-to-programming-write-short-programs-that-generate-graphics-and-animation <![CDATA[Introduction to programming. Write short programs that generate graphics and animation.]]> Introduction to programming. Write short programs that generate graphics and animation.

http://funprogramming.org/

]]> Ram Yash Pal https://bioinformaticsonline.com/pages/view/1897/genetic-test-in-india Sun, 11 Aug 2013 10:54:35 -0500 https://bioinformaticsonline.com/pages/view/1897/genetic-test-in-india <![CDATA[Genetic Test in India]]> 1.Xcode Life Sciences Pvt. Ltd.
6B, Eldorado, 
112, Nungambakkam High Road,
Nungambakkam, Chennai 600034
Tamil Nadu, India 

2.Mapmygenome™
Royal Demeure,HUDA Techno Enclave,
Plot No. 12/2, Sector-1 500 081 
Madhapur,Hyderabad
AP, India

3. DNA Labs India

http://www.dnalabsindia.com/lab.php

 

4.MedGenome Labs Pvt Ltd
(Division of SciGenom Labs Pvt Ltd.)
Plot no: 43A,SDF, 3rd floor
A Block,CSEZ, Kakanad, Cochin
Kerala - 682037 
Phone: 0484 - 2413399
Fax: 0484 - 2413398
Email: info@medgenome.com

5.Narayana Nethralaya

Narayana Hrudayalaya Campus
Narayana Health City
# 258/A, Bommasandra, Hosur Road, 
Bangalore - 560 099 - INDIA.
TEL: +91-80-66660655-0658 
FAX: +91-80-66660650 
Mobile: 9902 821128 (Emergency Only)
e-mail: info@narayananethralaya.com

6.BioAxis DNA Research Centre Private Limited
13-51,Sri Lakshmi Nagar colony,
Besides Big Bazar, Near Kamineni Hospitals
GSI Post BandalGuda (L B Nagar) Hydeabad-500068
Andhra Pradesh (India).
Phone : +91-40-24034503/+91-9246338983

7.Gene Guiide

8th Floor, Embassy Towers, 7 Bungalows Rd, Versova, Andheri West, Mumbai-61 
 09167 117799 
 info@geneguiide.com 

See more at: http://www.geneguiide.com

8.INDIAN BIOSCIENCES
Regd. Office:
G-2 (Ground Floor Rear), Kailash Colony, New Delhi - 110048, India.
Phone: +91 (0)11 29236088, Email: info@inbdna.com.

9.SRL Limited

GP-26, MARUTI INDUSTRIAL ESTATE,

UDYOG VIHAR,SECTOR-18,

GURGAON - 122015

Tel: 0124-3001243 / 0124-3001209

SRL Limited
VASANT VIHAR, 8, PALAM MARG,
NEW DELHI - 110057
Tel: 011 - 4229 5333 

Website: http://www.srlworld.com
National Customer care number:
Call Toll Free : 1800-222-660/1800-102-8282 
E-mail id: customercare@srl.in

10.Tata Memorial Centre,

Advanced Centre for Treatment, Research and Education in Cancer

Kharghar, Navi Mumbai - 410 210, INDIA.

Tel: +91-22-2740 5000

Fax: +91-22-2740 5085

E-mail: mail@actrec.gov.in

 

 

]]> Rahul Agarwal