<![CDATA[BOL: Related items]]> https://bioinformaticsonline.com/related/39236?offset=380 https://bioinformaticsonline.com/news/view/40789/complete-genome-sequence-of-wuhan-seafood-market-pneumonia-virus-is-out Fri, 31 Jan 2020 02:36:59 -0600 https://bioinformaticsonline.com/news/view/40789/complete-genome-sequence-of-wuhan-seafood-market-pneumonia-virus-is-out <![CDATA[Complete genome sequence of Wuhan seafood market pneumonia virus is out !]]> Wuhan-Hu-1 claimed at least 40 lives and infected at least 1300 others in China. Cases are now being reported from Thailand, Singapore, Malaysia, South Korea, Japan, Vietnam, Nepal, France, Australia and even as far as the US. On Jan 10 2020, while news of the first fatality was barely trickling in, the 29,903 letters constituting the viral genome from an affected individual in Wuhan had already been elucidated (even though a few corrections were made subsequently). All the viral genome sequences from affected individuals are very very close to each other. Several are identical and none has more than 5 differences (99.983% similarity). This strongly suggests that transmission into humans came from a single pointed source and happened very recently, between Sep-Dec 2019.

Check out the detail at https://www.ncbi.nlm.nih.gov/nuccore/MN908947

]]> Jit https://bioinformaticsonline.com/bookmarks/view/41459/jcvipython-utility-libraries-on-genome-assembly-annotation-and-comparative-genomics Tue, 17 Mar 2020 06:19:06 -0500 https://bioinformaticsonline.com/bookmarks/view/41459/jcvipython-utility-libraries-on-genome-assembly-annotation-and-comparative-genomics <![CDATA[JCVI:Python utility libraries on genome assembly, annotation and comparative genomics]]> Collection of Python libraries to parse bioinformatics files, or perform computation related to assembly, annotation, and comparative genomics.

https://github.com/tanghaibao/jcvi

More at https://github.com/tanghaibao/jcvi/wiki

Address of the bookmark: https://github.com/tanghaibao/jcvi

]]> Jit https://bioinformaticsonline.com/bookmarks/view/41599/haslr-a-hybrid-assembler-which-uses-both-second-and-third-generation-sequencing-reads Mon, 04 May 2020 02:04:03 -0500 https://bioinformaticsonline.com/bookmarks/view/41599/haslr-a-hybrid-assembler-which-uses-both-second-and-third-generation-sequencing-reads <![CDATA[HASLR: a hybrid assembler which uses both second and third generation sequencing reads]]> HASLR, a hybrid assembler which uses both second and third generation sequencing reads to efficiently generate accurate genome assemblies. Our experiments show that HASLR is not only the fastest assembler but also the one with the lowest number of misassemblies on all the samples compared to other tested assemblers. Furthermore, the generated assemblies in terms of contiguity and accuracy are on par with the other tools on most of the samples. Availability. HASLR is an open source tool available at https://github.com/vpc-ccg/haslr.

Address of the bookmark: https://github.com/vpc-ccg/haslr

]]> BioStar https://bioinformaticsonline.com/bookmarks/view/41991/sequence-ontology-bioinformatics-analysis-soba-tool-to-provide-a-simple-statistical-and-graphical-summary-of-an-annotated-genome Wed, 22 Jul 2020 10:11:13 -0500 https://bioinformaticsonline.com/bookmarks/view/41991/sequence-ontology-bioinformatics-analysis-soba-tool-to-provide-a-simple-statistical-and-graphical-summary-of-an-annotated-genome <![CDATA[Sequence Ontology Bioinformatics Analysis (SOBA) tool to provide a simple statistical and graphical summary of an annotated genome]]> We have developed the Sequence Ontology Bioinformatics Analysis (SOBA) tool to provide a simple statistical and graphical summary of an annotated genome. We envisage its use during annotation jamborees, genome comparison and for use by developers for rapid feedback during annotation software development and testing. SOBA also provides annotation consistency feedback to ensure correct use of terminology within annotations, and guides users to add new terms to the Sequence Ontology when required. SOBA is available at http://www.sequenceontology.org/cgi-bin/soba.cgi.

More at https://pubmed.ncbi.nlm.nih.gov/20494974/

Address of the bookmark: http://www.sequenceontology.org/cgi-bin/soba.cgi

]]> BioStar https://bioinformaticsonline.com/researchlabs/view/42900/svardal-lab Sat, 20 Feb 2021 10:01:19 -0600 <![CDATA[Svardal lab]]> In the Svardal lab they are interested how the astonishing natural diversity we see on earth came into being, by which forces it formed and how it is changing today. Hence, they are trying to understand the process of evolution, with mathematical models and through the analysis of genome sequencing data.

Genomes, and in particular differences between them, are a crucial source of information to understand evolution and biology in general. They provide a record of the evolutionary past of populations, their relatedness patterns, their demography, and their adaptations.

More at https://www.uantwerpen.be/en/staff/hannes-svardal/svardal-lab/

]]> https://bioinformaticsonline.com/bookmarks/view/43088/iva-accurate-de-novo-assembly-of-rna-virus-genomes Wed, 23 Jun 2021 07:51:59 -0500 https://bioinformaticsonline.com/bookmarks/view/43088/iva-accurate-de-novo-assembly-of-rna-virus-genomes <![CDATA[IVA: accurate de novo assembly of RNA virus genomes]]> IVA (Iterative Virus Assembler) designed specifically for read pairs sequenced at highly variable depth from RNA virus samples. We tested IVA on datasets from 140 sequenced samples from human immunodeficiency virus-1 or influenza-virus-infected people and demonstrated that IVA outperforms all other virus de novo assemblers.

Availability and implementation: The software runs under Linux, has the GPLv3 licence and is freely available from http://sanger-pathogens.github.io/iva

https://pubmed.ncbi.nlm.nih.gov/25725497/

Address of the bookmark: https://github.com/sanger-pathogens/iva

]]> Neel https://bioinformaticsonline.com/bookmarks/view/43364/ragtag-a-collection-of-software-tools-for-scaffolding-and-improving-modern-genome-assemblies Sat, 11 Sep 2021 00:28:14 -0500 https://bioinformaticsonline.com/bookmarks/view/43364/ragtag-a-collection-of-software-tools-for-scaffolding-and-improving-modern-genome-assemblies <![CDATA[RagTag: a collection of software tools for scaffolding and improving modern genome assemblies]]> RagTag is a collection of software tools for scaffolding and improving modern genome assemblies. Tasks include:

Address of the bookmark: https://github.com/malonge/RagTag

]]> Jit https://bioinformaticsonline.com/bookmarks/view/43770/chromeister-an-ultra-fast-heuristic-approach-to-detect-conserved-signals-in-extremely-large-pairwise-genome-comparisons Thu, 03 Feb 2022 04:01:55 -0600 https://bioinformaticsonline.com/bookmarks/view/43770/chromeister-an-ultra-fast-heuristic-approach-to-detect-conserved-signals-in-extremely-large-pairwise-genome-comparisons <![CDATA[chromeister: An ultra fast, heuristic approach to detect conserved signals in extremely large pairwise genome comparisons.]]> chromeister: An ultra fast, heuristic approach to detect conserved signals in extremely large pairwise genome comparisons.

USAGE:

  • -query: sequence A in fasta format
  • -db: sequence B in fasta format
  • -out: output matrix
  • -kmer Integer: k>1 (default 32) Use 32 for chromosomes and genomes and 16 for small bacteria
  • -diffuse Integer: z>0 (default 4) Use 4 for everything - if using large plant genomes you can try using 1
  • -dimension Size of the output matrix and plot. Integer: d>0 (default 1000) Use 1000 for everything that is not full genome size, where 2000 is recommended

Address of the bookmark: https://github.com/estebanpw/chromeister

]]> Jit https://bioinformaticsonline.com/researchlabs/view/43817/bioinfo-lab Fri, 04 Mar 2022 00:17:00 -0600 <![CDATA[Bioinfo Lab]]> The Institute of Bioinformatics conducts internationally renowned research and provides profound education in bioinformatics. Its research focuses on development and application of machine learning and statistical methods in biology and medicine.

Contact:
Computer Science Building (Science Park 3)
Altenberger Str. 69, A-4040 Linz, Austria
Tel. +43 732 2468 4520 / Fax +43 732 2468 4539
E-mail secretary@bioinf.jku.at

http://www.bioinf.jku.at/

]]> https://bioinformaticsonline.com/bookmarks/view/44307/genomenotebook Thu, 20 Apr 2023 13:19:01 -0500 https://bioinformaticsonline.com/bookmarks/view/44307/genomenotebook <![CDATA[genomenotebook]]> https://dbikard.github.io/genomenotebook/

Install

pip install genomenotebook

How to use

Create a simple genome browser with a search bar. The sequence appears when zooming in.

import genomenotebook as gn

g=gn.GenomeBrowser(genome_path, gff_path, init_pos=10000)
g.show()

Tracks can be added to visualize your favorite genomics data. See Examples for more !!!!

Address of the bookmark: https://dbikard.github.io/genomenotebook/

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