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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/39726?offset=200</link>
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	<description><![CDATA[]]></description>
	
	
<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/39827/prof-dr-med-andreas-ramming</guid>
  <pubDate>Wed, 07 Aug 2019 03:25:48 -0500</pubDate>
  <link></link>
  <title><![CDATA[Prof. Dr. med. Andreas Ramming]]></title>
  <description><![CDATA[
<p>In many autoimmune diseases, a misdirected immune response leads to chronic inflammation and subsequently to fibrotic and degenerative tissue remodeling. Therapeutic options are available for inflammatory joint diseases, but only about 40% of patients respond to these existing therapies on a permanent basis. In the remaining cases, these therapies miss their target from the beginning or later during the course of treatment failure. There are currently no causal therapies available for the treatment of fibrotic autoimmune diseases such as systemic sclerosis. Therefore, there is an urgent need to develop new therapeutic options for the treatment of fibrotic and synovitic autoimmune diseases. His group is therefore deal with the molecular mechanisms of these misdirected signaling pathways for the development of novel, targeted therapies</p>

<p>http://www.medizin3.uk-erlangen.de/forschung/arbeitsgruppen/matrixbiologie-entzuendliche-signalwege-in-arthritis-und-fibrose/</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40792/haslr-a-tool-for-rapid-genome-assembly-of-long-sequencing-reads</guid>
	<pubDate>Fri, 31 Jan 2020 05:50:15 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40792/haslr-a-tool-for-rapid-genome-assembly-of-long-sequencing-reads</link>
	<title><![CDATA[HASLR: a tool for rapid genome assembly of long sequencing reads]]></title>
	<description><![CDATA[<p><span>HASLR is a tool for rapid genome assembly of long sequencing reads. HASLR is a hybrid tool which means it requires long reads generated by Third Generation Sequencing technologies (such as PacBio or Oxford Nanopore) together with Next Generation Sequencing reads (such as Illumina) from the same sample.&nbsp;</span></p><p>Address of the bookmark: <a href="https://github.com/vpc-ccg/haslr" rel="nofollow">https://github.com/vpc-ccg/haslr</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42271/mcclintock-meta-pipeline-to-identify-transposable-element-insertions-using-next-generation-sequencing-data</guid>
	<pubDate>Tue, 27 Oct 2020 00:21:18 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42271/mcclintock-meta-pipeline-to-identify-transposable-element-insertions-using-next-generation-sequencing-data</link>
	<title><![CDATA[McClintock: Meta-pipeline to identify transposable element insertions using next generation sequencing data]]></title>
	<description><![CDATA[<p><span>an integrated bioinformatics pipeline for the detection of TE insertions in whole-genome shotgun data, called McClintock (</span><a href="https://github.com/bergmanlab/mcclintock">https://github.com/bergmanlab/mcclintock</a><span>), which automatically runs and standardizes output for multiple TE detection methods. We demonstrate the utility of McClintock by evaluating six TE detection methods using simulated and real genome data from the model microbial eukaryote,&nbsp;</span><em>Saccharomyces cerevisiae</em><span>.&nbsp;</span></p><p>Address of the bookmark: <a href="https://github.com/bergmanlab/mcclintock" rel="nofollow">https://github.com/bergmanlab/mcclintock</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44659/figeno-tool-for-plotting-sequencing-data-along-genomic-coordinates</guid>
	<pubDate>Tue, 17 Sep 2024 02:28:15 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44659/figeno-tool-for-plotting-sequencing-data-along-genomic-coordinates</link>
	<title><![CDATA[Figeno: Tool for plotting sequencing data along genomic coordinates.]]></title>
	<description><![CDATA[<p><span>Tool for plotting sequencing data along genomic coordinates.</span></p>
<div>
<pre><code>FIGENO is a
  FIGure
    GENerator
for GENOmics</code></pre>
</div>
<p dir="auto">With figeno, you can plot various types of sequencing data along genomic coordinates. Video overview:&nbsp;<a href="https://www.youtube.com/watch?v=h1cBeXoSYTA">https://www.youtube.com/watch?v=h1cBeXoSYTA</a>.</p>
<p dir="auto"><a href="https://github.com/CompEpigen/figeno/blob/main/docs/content/images/figeno.png" target="_blank"><img src="https://github.com/CompEpigen/figeno/raw/main/docs/content/images/figeno.png" alt="figeno" style="border: 0px;"></a></p><p>Address of the bookmark: <a href="https://github.com/CompEpigen/figeno" rel="nofollow">https://github.com/CompEpigen/figeno</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38008/quast-lg-versatile-genome-assembly-evaluation</guid>
	<pubDate>Thu, 25 Oct 2018 10:46:55 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38008/quast-lg-versatile-genome-assembly-evaluation</link>
	<title><![CDATA[QUAST-LG: Versatile genome assembly evaluation]]></title>
	<description><![CDATA[<p>QUAST-LG-a tool that compares large genomic de novo assemblies against reference sequences and computes relevant quality metrics. Since genomes generally cannot be reconstructed completely due to complex repeat patterns and low coverage regions, we introduce a concept of upper bound assembly for a given genome and set of reads, and compute theoretical limits on assembly correctness and completeness. Using QUAST-LG, we show how close the assemblies are to the theoretical optimum, and how far this optimum is from the finished reference.</p>
<h4>AVAILABILITY AND IMPLEMENTATION:</h4>
<p>http://cab.spbu.ru/software/quast-lg</p><p>Address of the bookmark: <a href="http://cab.spbu.ru/software/quast-lg/" rel="nofollow">http://cab.spbu.ru/software/quast-lg/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36994/minimap2-a-versatile-pairwise-aligner-for-genomic-and-spliced-nucleotide-sequences</guid>
	<pubDate>Wed, 20 Jun 2018 07:55:29 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36994/minimap2-a-versatile-pairwise-aligner-for-genomic-and-spliced-nucleotide-sequences</link>
	<title><![CDATA[minimap2: A versatile pairwise aligner for genomic and spliced nucleotide sequences]]></title>
	<description><![CDATA[git clone https://github.com/lh3/minimap2
cd minimap2 &amp;&amp; make
# long sequences against a reference genome
./minimap2 -a test/MT-human.fa test/MT-orang.fa &gt; test.sam
# create an index first and then map
./minimap2 -d MT-human.mmi test/MT-human.fa
./minimap2 -a MT-human.mmi test/MT-orang.fa &gt; test.sam
# use presets (no test data)
./minimap2 -ax map-pb ref.fa pacbio.fq.gz &gt; aln.sam       # PacBio genomic reads
./minimap2 -ax map-ont ref.fa ont.fq.gz &gt; aln.sam         # Oxford Nanopore genomic reads
./minimap2 -ax sr ref.fa read1.fa read2.fa &gt; aln.sam      # short genomic paired-end reads
./minimap2 -ax splice ref.fa rna-reads.fa &gt; aln.sam       # spliced long reads
./minimap2 -ax splice -k14 -uf ref.fa reads.fa &gt; aln.sam  # Nanopore Direct RNA-seq
./minimap2 -cx asm5 asm1.fa asm2.fa &gt; aln.paf             # intra-species asm-to-asm alignment
./minimap2 -x ava-pb reads.fa reads.fa &gt; overlaps.paf     # PacBio read overlap
./minimap2 -x ava-ont reads.fa reads.fa &gt; overlaps.paf    # Nanopore read overlap
# man page for detailed command line options
man ./minimap2.1<p>Address of the bookmark: <a href="https://github.com/lh3/minimap2" rel="nofollow">https://github.com/lh3/minimap2</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43766/genometools-the-versatile-open-source-genome-analysis-software</guid>
	<pubDate>Wed, 02 Feb 2022 04:00:21 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43766/genometools-the-versatile-open-source-genome-analysis-software</link>
	<title><![CDATA[GenomeTools: The versatile open source genome analysis software]]></title>
	<description><![CDATA[<p>The&nbsp;<em>GenomeTools</em>&nbsp;genome analysis system is a&nbsp;<a href="http://genometools.org/license.html">free</a>&nbsp;collection of bioinformatics&nbsp;<a href="http://genometools.org/tools.html">tools</a>&nbsp;(in the realm of genome informatics) combined into a single binary named&nbsp;<em>gt</em>. It is based on a C library named &ldquo;libgenometools&rdquo; which consists of several modules.</p>
<p><img src="http://genometools.org/images/annotation.png" alt="image" style="border: 0px;"></p>
<p>If you are interested in gene prediction, have a look at&nbsp;<a href="http://genomethreader.org/" title="GenomeThreader gene prediction        software"><em>GenomeThreader</em></a>.</p>
<p>http://genometools.org/pub/</p><p>Address of the bookmark: <a href="http://genometools.org/" rel="nofollow">http://genometools.org/</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/843/structural-polymorphism-analysis-from-ngs-data</guid>
  <pubDate>Sat, 13 Jul 2013 17:12:47 -0500</pubDate>
  <link></link>
  <title><![CDATA[Structural polymorphism analysis from NGS data]]></title>
  <description><![CDATA[
<p>The LabEx BASC (Biodiversity, Agroecosystems, Society, Climate), a network of 13 laboratories of the Paris-Saclay Scientific Cluster, is seeking a bioinformatician to analyze Next Generation Sequencing (NGS) data analysis. In the context of a flagship project aiming at understanding and improving the adaptive capacity of agroecosystems it will be critical to establish a link between sequence variation, functional variation, gene/protein expression and phenotypic adaptation.</p>

<p>The successful candidate will be in charge of the detection of polymorphisms including structural variants, of the comparison of multiple and diverse genomes of a same species and of the construction of pan- and core-genomes. These challenging tasks will require bioinformatics developments and implementation of methods for accommodating the high level of repetitiveness of complex genomes. The tools will be integrated into pipelines and made available to end-users through the Galaxy platform. The bioinformatician will therefore also have to provide researchers with advices on their experimental designs in order to ensure compliance of produced datasets with pipelines requirements. He/she will be hosted by a bioinformatics/informatics team (7 people) (http://moulon.inra.fr/index.php/fr/equipestransversales/atelier-de-bioinformatique) which has computational facilities and expertise in NGS data analysis, and will benefit as well from national and international collaborative networks (Aplibio http://www.renabi.fr/platforms/aplibio/, Transplant http://transplantdb.eu, AMAIZING http://www.amaizing.fr/).</p>

<p>The position requires a doctoral degree (PhD) in bioinformatics with strong expertise in script writing (Python/Perl) and pipeline development. </p>

<p>Applicants should send a CV and the names of 2 referees willing to provide a letter of recommendation to joets@moulon.inra.fr.</p>
]]></description>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/2054/postdoc-positions-mammalian-transcriptome-evolution-at-sib</guid>
  <pubDate>Mon, 12 Aug 2013 19:58:33 -0500</pubDate>
  <link></link>
  <title><![CDATA[Postdoc Positions - Mammalian Transcriptome Evolution at SIB]]></title>
  <description><![CDATA[
<p>BIOINFORMATICS POSTDOC IN FUNCTIONAL EVOLUTIONARY GENOMICS</p>

<p>Center for Integrative Genomics, University of Lausanne, Switzerland</p>

<p>Two postdoctoral positions (2 years with possible extensions up to 5 years) are available immediately in the evolutionary genomics group of Henrik Kaessmann.</p>

<p>We are seeking highly qualified and enthusiastic applicants with strong skills in computational biology/bioinformatics, preferably also with experience in data mining and comparative or evolutionary genome analysis.</p>

<p>We have been interested in a range of topics related to the functional evolution of genomes from primates (e.g., the emergence of new genes and their functions) and other mammals (e.g., the origin and evolution of mammalian sex chromosomes). In the framework of a recently launched series of projects, a large amount of transcriptome and genome (e.g., epigenome) data are being produced by the wet lab unit of the group using next generation sequencing technologies for a unique collection of tissues from representative mammals and outgroup species (e.g., birds). Topics of current projects based on these data include the origins and/or evolution of protein-coding genes, alternative splicing, microRNAs, long noncoding RNAs, and dosage compensation.</p>

<p>The postdoctoral fellow will perform integrated evolutionary/bioinformatics analyses based on data produced in the lab and available genomic data. The specific project will be developed together with the candidate.</p>

<p>The language of the institute is English, and its members form an international group that is rapidly expanding. The institute is located in Lausanne, a beautiful city at Lake Geneva.</p>

<p>For more information on the group and our institute more generally, please refer to our website: http://www.unil.ch/cig/page7858_en.html</p>

<p>Please submit a CV, statement of research interest, and names of three references to: Henrik Kaessmann (Henrik.Kaessmann@unil.ch).</p>

<p>Webpage : http://www.unil.ch/cig/page7858.html</p>
]]></description>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/6961/research-assistant-national-bureau-of-animal-genetic-resources</guid>
  <pubDate>Tue, 03 Dec 2013 06:17:34 -0600</pubDate>
  <link></link>
  <title><![CDATA[Research Assistant @ NATIONAL BUREAU OF ANIMAL GENETIC RESOURCES]]></title>
  <description><![CDATA[
<p>NATIONAL BUREAU OF ANIMAL GENETIC RESOURCES<br />Near Basant Vihar G.T. Road Bypass<br />P.O. Box No.129, Karnal-132001 (Haryana)</p>

<p>WALK-IN-INTERVIEW</p>

<p>A walk-in-Interview is proposed to be held at National Bureau of Animal Genetic Resources, Karnal (Haryana)-132001 at 11:30 AM on 18.12.2013 to select One RA and One SRF as per details given below:</p>

<p>1. One post of Research Associate under DBT sponsored Support under BIPP for the “SanGenix: A comprehensive Next Generation Sequence (NGS) data analysis solution” as Grants in AID. Thepost duration is Upto 31st March 2015 or earlier.</p>

<p>2. One post of Senior Research Fellow under NAIP (Component-4) Bioprospecting of genes and allele mining for abiotic stress tolerance. The post duration is Upto 31st March 2014 or earlier</p>

<p>Essential Qualifications: Ph.D. in Bioinformatics/ Computer Application or<br />First Class Masters degree in Bioinformatics/ Computer Application with two years experience as evidenced by Publications.</p>

<p>Desirable: Experience in the field of handling Next generation Sequencing Data.</p>

<p>Emolument: Rs. 22,000/- per month + HRA as per admissibility</p>

<p>Age Limit:</p>

<p>40 years for Men<br />45 years for women as on date of interview</p>

<p>Research Associate: ONE</p>

<p>Duration of engagement: Upto</p>

<p>31st March 2015 or earlier &amp; Coterminus with the project</p>

<p>Responsibilities: To help the PI for Beta testing and development of the SanGenix Tool for NGS data.</p>

<p>Essential Qualifications: First Class Masters’ degree in Bioinformatics/Biotechnology.</p>

<p>Desirable: Experience in the field of Biotechnology/ Bioinformatics</p>

<p>Emoluments:</p>

<p>Rs. 16,000/- per month + HRA as per admissibility.<br />Senior Research Fellow: ONE<br />Duration of engagement: Upto 31st March 2014 or earlier &amp; Coterminus with the project</p>

<p>Age Limit</p>

<p>35 years for men<br />40 years for women as on date of interview</p>

<p>Note: Relaxation in age will be admissible for SC/ST &amp; OBC candidates as per Govt. of India /ICAR norms</p>

<p>1. The applicants must bring with them original documents and brief of research work done during post graduation along with a set of photocopy and latest two passport size photographs.<br />2. A panel of selected candidates will also be made which may be utilized for filling of positions of shorter durations in future if demand arises.<br />3. Experience certificate in original, if any 4. The above positions are purely on temporary basis and are co-terminus with the project. No TA/DA will be paid to attend the interview.<br />5. Any other clarifications can be had on the date of interview.<br />6. The Director’s decision will be final and binding on all respects.</p>

<p>Advertisement: http://210.212.93.85/rasrfadvertise.pdf</p>
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