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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/39875?offset=360</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43090/loretta-a-user-friendly-tool-for-assembling-viral-genomes-from-pacbio-sequence-data</guid>
	<pubDate>Wed, 23 Jun 2021 07:54:53 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43090/loretta-a-user-friendly-tool-for-assembling-viral-genomes-from-pacbio-sequence-data</link>
	<title><![CDATA[LoReTTA, a user-friendly tool for assembling viral genomes from PacBio sequence data]]></title>
	<description><![CDATA[<p>LoReTTA (Long Read Template-Targeted Assembler), a tool designed for performing <em>de novo</em> assembly of long reads generated from viral genomes on the PacBio platform. LoReTTA exploits a reference genome to guide the assembly process, an approach that has been successful with short reads.</p>
<p>https://academic.oup.com/ve/article/7/1/veab042/6248116</p><p>Address of the bookmark: <a href="https://academic.oup.com/ve/article/7/1/veab042/6248116" rel="nofollow">https://academic.oup.com/ve/article/7/1/veab042/6248116</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44313/orthovenn3-an-integrated-platform-for-exploring-and-visualizing-orthologous-data-across-genomes</guid>
	<pubDate>Tue, 02 May 2023 00:48:28 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44313/orthovenn3-an-integrated-platform-for-exploring-and-visualizing-orthologous-data-across-genomes</link>
	<title><![CDATA[OrthoVenn3: an integrated platform for exploring and visualizing orthologous data across genomes]]></title>
	<description><![CDATA[<p><span>OrthoVenn3 is a powerful tool for comparative genomics analysis, used as a web server for full genome comparisons, annotation, and evolutionary analysis of orthologous clusters across multiple species. It has already been used by thousands of users from over 60 countries.</span></p><p>Address of the bookmark: <a href="https://orthovenn3.bioinfotoolkits.net/" rel="nofollow">https://orthovenn3.bioinfotoolkits.net/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/21443/a-guide-for-complete-r-beginners-getting-data-into-r</guid>
	<pubDate>Tue, 24 Feb 2015 20:15:08 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/21443/a-guide-for-complete-r-beginners-getting-data-into-r</link>
	<title><![CDATA[A guide for complete R beginners :- Getting data into R]]></title>
	<description><![CDATA[<p>For a beginner this can be is the hardest part, it is also the most important to get right.</p><p>It is possible to create a vector by typing data directly into R using the combine function &lsquo;c&rsquo;</p><blockquote><p><strong>x </strong></p></blockquote><p>same as</p><blockquote><p><strong>x </strong></p></blockquote><p>creates the vector x with the numbers between 1 and 5.</p><p>You can see what is in an object at any time by typing its name;</p><blockquote><p><strong>x</strong></p></blockquote><p>will produce the output<strong> &lsquo;[1] 1 2 3 4 5&prime;</strong></p><p>Note that names need to be quoted</p><blockquote><p><strong>daysofweek </strong><strong>&larr; c(&lsquo;Monday&rsquo;, &lsquo;Tuesday&rsquo;, &lsquo;Wednesday&rsquo;, &lsquo;Thursday&rsquo;, &lsquo;Friday&rsquo;);</strong></p></blockquote><p>Usually however you want to input from a file. We have touched on the &lsquo;read.table&rsquo; function already.</p><blockquote><p><strong>mydata </strong></p></blockquote><p>Now <strong>mydata</strong> is a data frame with multiple vectors</p><p>each vector can be identified by the default syntax</p><p>#if any of these are typed it will print to screen</p><blockquote><p><strong>mydata$V1 mydata$V2 mydata$V3 </strong></p></blockquote><p>By default the function assumes certain things from the file</p><ul>
<li>The file is a plain text file (there are function to read excel files: <em>not covered here</em>)</li>
<li>columns are separated by any number of tabs or spaces</li>
<li>there is the same number of data points in each column</li>
<li>there is no header row (labels for the columns)</li>
<li>there is no column with names for the rows** [I&rsquo;ll explain].</li>
</ul><p><span style="text-decoration: underline;">If any of these are false, we need to tell that to the function</span></p><p>If it has a header column</p><blockquote><p><strong>mydata <em>header=T also works</em></strong></p></blockquote><p>Note that there is a comma between different parts of the functions arguments</p><p>If there is one less column in the header row, then R assumes that the 1<sup>st</sup> column of data after the header are the row names</p><p>Now the vectors (columns) are identified by their name</p><p>#if any of these are typed it will print to screen</p><blockquote><p><strong>mydata$A mydata$B mydata$C </strong></p></blockquote><p># Summary about the whole data frame</p><blockquote><p><strong>summary(mydata)</strong></p></blockquote><p># Summary information of column A</p><blockquote><p><strong>summary(mydata$A) </strong></p></blockquote><p>We can shortcut having to type the data frame each time by attaching it</p><blockquote><p><strong>attach(mydata)</strong></p></blockquote><p># summary of column B as &lsquo;mydata&rsquo; is attached</p><blockquote><p><strong>summary(B)</strong></p></blockquote><p><span style="text-decoration: underline;">Two other important options for </span><em><span style="text-decoration: underline;">read.table</span></em></p><p>If is is separated only by tabs and has a header</p><blockquote><p><strong>mydata </strong></p></blockquote><p>Really useful if you have spaces in the contents of some columns, so R does not mess up reading the columns . However if the columns or of an uneven length it will tell you.</p><p>If you know that the file has uneven columns</p><blockquote><p><strong>mydata </strong></p></blockquote><p>This causes R to fill empty spaces in a columns with &lsquo;NA&rsquo; .</p><p>The last two examples will still work with our file and give the same result as with only headers=T</p><p><span style="text-decoration: underline;">Graphs</span></p><p>to get an idea of what R is capable of type</p><blockquote><p><strong>demo(graphics)</strong></p></blockquote><p>steps through the examples, and the code is printed to the screen</p><p>We will work with simpler examples that have immediate use to biologists.</p><p>Remember to get more information about the options to a function type &lsquo;?function&rsquo;</p><p><span style="text-decoration: underline;">Histogram of A</span><span style="text-decoration: underline;"></span></p><blockquote><p><strong>hist(mydata$A)</strong></p></blockquote><p>If there was more data we could increase the number of vertical columns with the option, breaks=50 (or another relevant number).</p><blockquote><p><strong>boxplot(mydata)</strong></p></blockquote><p>We can get rid of the need to type the data frame each time by using the <strong>attach</strong> function</p><p># if not already done so</p><blockquote><p><strong>attach(mydata) </strong></p><p><strong>boxplot(mydata$A, mydata$B, name=c(&ldquo;Value A&rdquo;, &ldquo;Value B&rdquo;) , ylab=&ldquo;Count of Something&rdquo;)</strong></p></blockquote><p>same as</p><blockquote><p><strong>boxplot(A, B, name=c(&ldquo;Value A&rdquo;, &ldquo;Value B&rdquo;) , ylab=&ldquo;Count of Something&rdquo;)</strong></p></blockquote><p><span style="text-decoration: underline;">Scatter plot</span></p><p># if not already done so</p><blockquote><p><strong>attach(mydata) </strong></p><p><strong>plot(A,B) # or plot(mydata$A, mydata$B)</strong></p></blockquote><p><strong><span style="text-decoration: underline;">SAVING an image</span></strong></p><p>Windows users (Rgui) RIGHT click on image and select which you want.</p><p><span style="text-decoration: underline;">These instructions work for everyone.</span></p><p>You need to create a new device of the type of file you need, then send the data to that device</p><p>to save as a png file (easy to load into the likes of powerpoint, also great for web applications.</p><blockquote><p><strong>png(&lsquo;filename&rsquo;) </strong></p><p><strong>boxplot(A, B, name=c(&ldquo;Value A&rdquo;, &ldquo;Value B&rdquo;) , ylab=&ldquo;Count of Something&rdquo;)</strong></p></blockquote><p>or to save as a pdf</p><blockquote><p><strong>pdf(&lsquo;filename&rsquo;) </strong></p><p><strong>boxplot(A, B, name=c(&ldquo;Value A&rdquo;, &ldquo;Value B&rdquo;) , ylab=&ldquo;Count of Something&rdquo;)</strong></p></blockquote><p><span style="text-decoration: underline;">Note</span></p><ul>
<li>Nothing will appear on screen, the output is going to the file</li>
<li>Also it may not be saved immediately but will once the device (or R) is turned quit.</li>
</ul><p>To quit R type</p><p><strong>q() # </strong>If you save your session, next time you start R, you will have your data preloaded.</p><p>Or if you want to remain in R</p><blockquote><pre><strong>dev.off() #</strong>turns of the png (or pdf etc) device, thus forces the data to save</pre></blockquote>]]></description>
	<dc:creator>Archana Malhotra</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/37586/julia-programming-language-a-python-and-r-rival</guid>
	<pubDate>Sat, 25 Aug 2018 04:46:39 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/37586/julia-programming-language-a-python-and-r-rival</link>
	<title><![CDATA[Julia Programming Language, a Python and R rival]]></title>
	<description><![CDATA[<p>Big data has grown to become one of the most lucrative fields. In fact, data scientists are some of the most sought people. They are usually hired to analyze, control and parse large chunks of data. Implementing these actions using traditional techniques is not a walk in the park. This is why most data scientists prefer using programming languages such as R and Python. However, there is one more programming language that can do the job. That is Julia programming language.</p><p>What Is Julia Language?</p><p>Julia is a programming language that came into the limelight in 2012. It is a general-purpose programming language that was designed for solving scientific computations. Julia was meant to be an alternative to Python, R and other programming languages that were mainly used for manipulating data. This is because it has numerous features that can minimize the complexities of numerical computations.&nbsp;</p><p>Julia optimizes on the best features of Python and R while at the same time overlooks their weaknesses. This explains why it is viewed as an alternative to these programming languages. For instance, it utilizes the readability and simplicity of Python then performs faster.</p><p>Julia is the most preferred programming language for data scientists and mathematicians. This is because its core features are similar to the ones that are used on most data software. Also, the language is ideal for these two subjects because its syntax is similar to the standard mathematical formulas.</p><p>Key Features Of Julia Language<br />Uses JIT Compilation<br />Parallelism<br />Dynamic Typing<br />Simple Syntax<br />Allows Metaprogramming<br />Accessible to Libraries<br />-1-Array Indexing</p><p>Julia Vs Python And R Programming Languages<br />1. Speed<br />Julia is faster than both Python and R. This is a very critical aspect that is given special attention in the big data programming. The high speed of Julia is because of JIT compilers. You will need to install external libraries on Python to achieve similar speed.</p><p>2. Syntax<br />Julia has a math-friendly syntax. The syntax of this programming language is similar to the mathematical formulas hence can be used to perform mathematical and scientific computations. This syntax makes it easier to learn than Python.</p><p>3. Parallelism<br />Although both Python and R use parallelism, Julia uses a top-level parallelism. Julia allows the processor to perform to the optimum level than what Python and R can achieve.</p><p>4. Versatility<br />Julia programming language is more versatile than Python and R. It allows a programmer to move from different codes and functions with ease.</p><p>The only area that Python and R are superior to Julia is in terms of community. Given that Julia is a new programming language, it has a small community as compared to others which have been around for years.</p><p>In overall Julia programming language is a better alternative that you can use to handle Big data projects. Despite having a small community, it is one of those programming languages that you can easily learn.</p>]]></description>
	<dc:creator>Radha Agarkar</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38634/eyechrom-visualizing-chromosome-count-data-from-plants</guid>
	<pubDate>Tue, 08 Jan 2019 10:20:54 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38634/eyechrom-visualizing-chromosome-count-data-from-plants</link>
	<title><![CDATA[EyeChrom: Visualizing Chromosome Count Data From Plants]]></title>
	<description><![CDATA[<p><span>It's goal is to show chromosmal data per genus. Select the genus, and the plot will show the records found for it in the Chromosome Counts Database. note: Report an issue via Gihub: github.com/roszenil/CCDBcurator and github.com/RodrigoRivero/EyeChrom</span></p>
<p>https://bsapubs.onlinelibrary.wiley.com/doi/pdf/10.1002/aps3.1207</p><p>Address of the bookmark: <a href="http://eyechrom.com:3838/EyeChrom/" rel="nofollow">http://eyechrom.com:3838/EyeChrom/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42581/autogluon-automl-for-text-image-and-tabular-data</guid>
	<pubDate>Thu, 07 Jan 2021 05:33:17 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42581/autogluon-automl-for-text-image-and-tabular-data</link>
	<title><![CDATA[AutoGluon: AutoML for Text, Image, and Tabular Data]]></title>
	<description><![CDATA[<p><span>AutoGluon automates machine learning tasks enabling you to easily achieve strong predictive performance in your applications. With just a few lines of code, you can train and deploy high-accuracy machine learning and deep learning models on text, image, and tabular data.</span></p><p>Address of the bookmark: <a href="https://github.com/awslabs/autogluon" rel="nofollow">https://github.com/awslabs/autogluon</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44742/nasa-open-science-data-repository</guid>
	<pubDate>Wed, 18 Dec 2024 11:54:47 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44742/nasa-open-science-data-repository</link>
	<title><![CDATA[NASA Open Science Data Repository]]></title>
	<description><![CDATA[<p><span>The NASA Open Science Data Repository (OSDR) enables access to space-related data from experiments and missions that investigate biological and health responses of terrestrial life to spaceflight. The goal of OSDR is to enable multi-modal and multi-hierarchical fundamental space life science data be reused toward basic science, applied science, and operational outcomes for space exploration and knowledge discovery. These data include &lsquo;omics, phenotypic, physiological, behavioral, hardware, environmental telemetry; raw, processed; tabular, text, code, bioimaging, and video.</span></p>
<p><span>https://www.nasa.gov/reference/osdr-data-processing/</span></p><p>Address of the bookmark: <a href="https://www.nasa.gov/osdr/" rel="nofollow">https://www.nasa.gov/osdr/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36403/ngmlr-long-read-mapper-designed-to-align-pacbio-or-oxford-nanopore</guid>
	<pubDate>Wed, 25 Apr 2018 07:30:54 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36403/ngmlr-long-read-mapper-designed-to-align-pacbio-or-oxford-nanopore</link>
	<title><![CDATA[NGMLR: long-read mapper designed to align PacBio or Oxford Nanopore]]></title>
	<description><![CDATA[<p><span>CoNvex Gap-cost alignMents for Long Reads (ngmlr) is a long-read mapper designed to sensitively align PacBilo or Oxford Nanopore to (large) reference genomes. It was designed to quickly and correctly align the reads, including those spanning (complex) structural variations. Ngmlr uses an SV aware k-mer search to find approximate mapping locations for a read and then a banded Smith-Waterman alignment algorithm to compute the final alignment. Ngmlr uses a convex gap cost model that penalizes gap extensions for longer gaps less than for shorter ones to compute precise alignments. The gap model allows ngmlr to account for both the sequencing error and real genomic variations at the same time and makes it especially effective at more precisely identifying the position of breakpoints stemming from structural variations. The k-mer search helps to detect and split reads that cannot be aligned linearly, enabling ngmlr to reliably align reads to a wide range of different structural variations including nested SVs (e.g. inversions flanked by deletions).</span></p><p>Address of the bookmark: <a href="https://github.com/philres/ngmlr" rel="nofollow">https://github.com/philres/ngmlr</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/39098/sda-long-read-sequence-and-assembly-of-segmental-duplications</guid>
	<pubDate>Tue, 05 Mar 2019 10:00:57 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/39098/sda-long-read-sequence-and-assembly-of-segmental-duplications</link>
	<title><![CDATA[SDA: Long-read sequence and assembly of segmental duplications]]></title>
	<description><![CDATA[<p><span><span>Segmental Duplication Assembler (SDA; https://github.com/mvollger/SDA) constructs graphs in which paralogous sequence variants define the nodes and long-read sequences provide attraction and repulsion edges, enabling the partition and assembly of long reads corresponding to distinct paralogs.<br></span></span></p>
<p><span><span>https://github.com/mvollger/SDA</span></span></p><p>Address of the bookmark: <a href="https://www.nature.com/articles/s41592-018-0236-3" rel="nofollow">https://www.nature.com/articles/s41592-018-0236-3</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/file/view/989/bioinformatics-approach-to-boar-taint</guid>
	<pubDate>Wed, 17 Jul 2013 15:50:37 -0500</pubDate>
	<link>https://bioinformaticsonline.com/file/view/989/bioinformatics-approach-to-boar-taint</link>
	<title><![CDATA[Bioinformatics approach to Boar Taint]]></title>
	<description><![CDATA[<p><span>Meat products obtained from intact male pigs often produce offensive smell or odour which is recognized as a complex genetic trait called boar taint.Androstenone and Skatole&nbsp;in the fat primarily cause boar taint. Metabolism of androstenone and sex steroids share a common pathway which makes removal of boar taint a very challenging task. Castration is a traditional solution to remove boar taint but it also results in bad quality of meat due to low level of steroids which is objectionable to many consumers. Detected functional variant(s) underlying boar taint compounds can be used as genetic markers in selection of male pigs with reduced boar taint levels. Resequencing of a total of 47 samples belong to Norwegian Landrace (NL) and Duroc (D) pigs with varied boar taint levels were done in Illumina HiSeq2000 to &gt;10X average coverage. Short reads generated from these samples mapped to&nbsp;<em>Sus Scrofa</em>&nbsp;version 10.2 reference assembly using Bowtie2. Alignment file then used for calling SNPs and InDels inside previousy identified QTL regions on SSC5,13, and 7 with the aid of FreeBayes , a variant caller tool. A final list of SNPs was prepared after filtering SNPs on the basis of SNP quality, coverage of SNP allele, functional and structural annotation, and repeats, etc. Selected SNPs will be genotyped in sample population for validation and then used for constructing SNPs haplotypes in close linkage disequilibrium with QTLs and fine mapping of QTLs through association mapping of genotyped SNPs.</span><span>&nbsp;</span></p><p><span>&nbsp;</span></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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