<![CDATA[BOL: Related items]]> https://bioinformaticsonline.com/related/39903?offset=540 https://bioinformaticsonline.com/news/view/22793/sequencing-by-xpansion Wed, 17 Jun 2015 20:58:11 -0500 https://bioinformaticsonline.com/news/view/22793/sequencing-by-xpansion <![CDATA[Sequencing By Xpansion]]> Sequencing By Xpansion (SBX) is a DNA sequencing method that uses a simple biochemical reaction to encode the sequence of a DNA molecule into a highly measurable surrogate called an Xpandomer. This single molecule approach produces enough Xpandomer in a single drop reaction to sequence an entire human genome 1000X over. To achieve this, an Xpandomer replaces each DNA sequence with a sequence of large, high signal reporter molecules using the SBX molecular expansion technology. The DNA sequence is then read out as the Xpandomer reporters pass sequentially through a nanopore detector. SBX is a molecular engineering platform that benefits from core design principles that separate the multiple molecular functions. This systems approach enables efficient development and incorporation of improvements to SBX and is key to reconfiguring and optimizing Xpandomer measurement for different detection platforms.

http://www.stratosgenomics.com/stratos-genomics-technology

]]> Jitendra Narayan https://bioinformaticsonline.com/researchlabs/view/26499/katju-lab Fri, 26 Feb 2016 03:25:32 -0600 <![CDATA[Katju Lab]]> TheLab seek to understand the genetic factors contributing to genomic variation and phenotypic diversity. To this end, we employ molecular and bioinformatic tools to study evolutionary processes at the level of populations, both experimental and natural, and genomes. Our research interests encompass a wide range of topics, including the evolution of organellar and nuclear genomes, gene duplication and the origin of novel function, and the fitness and phenotypic consequences of mutation in evolution. For details regards ongoing projects, please see the Research page.

http://katjulab.com/research.html

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