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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/40221?offset=50</link>
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	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34812/building-web-uis-with-mojolicious-perl</guid>
	<pubDate>Tue, 26 Dec 2017 18:06:57 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34812/building-web-uis-with-mojolicious-perl</link>
	<title><![CDATA[Building Web UIs With Mojolicious Perl]]></title>
	<description><![CDATA[<p>Mojolicious is one of 3 leading web frameworks available in the perl ecosystem (along with Dancer and Catalyst) and by far my favorite.</p>
<p>Mojolicious aims to provide a complete web development experience. It thus has no hard dependencies, comes with a built-in development and production server and many other features one needs to build a web application. It's easy to install, has an applciation generator script and many plugins and extensions.</p>
<p><em>Libraries for developing Web applications</em></p>
<ul>
<li><a href="https://metacpan.org/pod/Amon2">Amon2</a></li>
<li><a href="https://metacpan.org/pod/Catalyst">Catalyst</a>&nbsp;- Overflowing with features. Very popular.</li>
<li><a href="https://metacpan.org/pod/Dancer">Dancer</a>&nbsp;(<a href="http://perldancer.org/">Official site</a>)</li>
<li><a href="https://metacpan.org/pod/Dancer2">Dancer2</a></li>
<li><a href="https://metacpan.org/pod/Gantry">Gantry</a>&nbsp;- Web application framework for mod_perl, cgi, etc.</li>
<li><a href="https://metacpan.org/pod/Kossy">Kossy</a>&nbsp;- A Web framework with simple interface.</li>
<li><a href="https://metacpan.org/pod/Mojolicious">Mojolicious</a>&nbsp;- An all in one framework.</li>
<li><a href="https://metacpan.org/pod/Poet">Poet</a>&nbsp;- a modern Perl web framework for Mason developers</li>
</ul><p>Address of the bookmark: <a href="https://www.ynonperek.com/2017/09/28/perl-mojolicious-web-development/" rel="nofollow">https://www.ynonperek.com/2017/09/28/perl-mojolicious-web-development/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/35252/hgt-finder-a-new-tool-for-horizontal-gene-transfer-finding-and-application-to-aspergillus-genomes</guid>
	<pubDate>Wed, 17 Jan 2018 05:03:19 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/35252/hgt-finder-a-new-tool-for-horizontal-gene-transfer-finding-and-application-to-aspergillus-genomes</link>
	<title><![CDATA[HGT-Finder: A New Tool for Horizontal Gene Transfer Finding and Application to Aspergillus genomes]]></title>
	<description><![CDATA[<p><span>HGT-Finder: </span></p>
<p><span>(i) can be used for HGT detection in both prokaryotes and eukaryotes, </span></p>
<p><span>(ii) can report a statistical&nbsp;</span><em>P</em><span>&nbsp;value for each gene to indicate how likely it is to be horizontally transferred, and </span></p>
<p><span>(iii) is fully automated (requires minimal human intervention), as well as very easy to install and run.&nbsp;</span></p><p>Address of the bookmark: <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626719/" rel="nofollow">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626719/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/34552/edit-distance-application-in-bioinformatics</guid>
	<pubDate>Thu, 07 Dec 2017 08:46:51 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/34552/edit-distance-application-in-bioinformatics</link>
	<title><![CDATA[Edit distance application in bioinformatics !]]></title>
	<description><![CDATA[<p>There are other popular measures of&nbsp;<a href="https://en.wikipedia.org/wiki/Edit_distance" title="Edit distance">edit distance</a>, which are calculated using a different set of allowable edit operations. For instance,</p><ul>
<li>the&nbsp;<a href="https://en.wikipedia.org/wiki/Damerau%E2%80%93Levenshtein_distance" title="Damerau&ndash;Levenshtein distance">Damerau&ndash;Levenshtein distance</a>&nbsp;allows insertion, deletion, substitution, and the&nbsp;<a href="https://en.wikipedia.org/wiki/Transposition_(mathematics)" title="Transposition (mathematics)">transposition</a>&nbsp;of two adjacent characters;</li>
<li>the&nbsp;<a href="https://en.wikipedia.org/wiki/Longest_common_subsequence_problem" title="Longest common subsequence problem">longest common subsequence</a>&nbsp;(LCS) distance allows only insertion and deletion, not substitution;</li>
<li>the&nbsp;<a href="https://en.wikipedia.org/wiki/Hamming_distance" title="Hamming distance">Hamming distance</a>&nbsp;allows only substitution, hence, it only applies to strings of the same length.</li>
<li>the&nbsp;<a href="https://en.wikipedia.org/wiki/Jaro_distance" title="Jaro distance">Jaro distance</a>&nbsp;allows only&nbsp;<a href="https://en.wikipedia.org/wiki/Transposition_(mathematics)" title="Transposition (mathematics)">transposition</a>.</li>
</ul><p>&nbsp;</p><pre><span>use</span> Text<span>::</span>Levenshtein <span>qw</span><span>(</span>distance<span>);</span>

 <span>print</span> <span>distance</span><span>(</span><span>"foo"</span><span>,</span><span>"four"</span><span>);</span>
 <span># prints "2"</span>

 <span>my</span> <span>@words</span>     <span>=</span> <span>qw</span><span>/ four foo bar /</span><span>;</span>
 <span>my</span> <span>@distances</span> <span>=</span> <span>distance</span><span>(</span><span>"foo"</span><span>,</span><span>@words</span><span>);</span>

 <span>print</span> <span>"@distances"</span><span>;</span>
 <span># prints "2 0 3"</span><br /><br /><br /></pre><pre><span>use</span> Algorithm<span>::</span>LCSS <span>qw</span><span>(</span> LCSS CSS CSS_Sorted <span>);</span>
    <span>my</span> <span>$lcss_ary_ref</span> <span>=</span> <span>LCSS</span><span>(</span> <span>\</span><span>@SEQ1</span><span>,</span> <span>\</span><span>@SEQ2</span> <span>);</span>  <span># ref to array</span>
    <span>my</span> <span>$lcss_string</span>  <span>=</span> <span>LCSS</span><span>(</span> <span>$STR1</span><span>,</span> <span>$STR2</span> <span>);</span>    <span># string</span>
    <span>my</span> <span>$css_ary_ref</span> <span>=</span> <span>CSS</span><span>(</span> <span>\</span><span>@SEQ1</span><span>,</span> <span>\</span><span>@SEQ2</span> <span>);</span>    <span># ref to array of arrays</span>
    <span>my</span> <span>$css_str_ref</span> <span>=</span> <span>CSS</span><span>(</span> <span>$STR1</span><span>,</span> <span>$STR2</span> <span>);</span>      <span># ref to array of strings</span>
    <span>my</span> <span>$css_ary_ref</span> <span>=</span> <span>CSS_Sorted</span><span>(</span> <span>\</span><span>@SEQ1</span><span>,</span> <span>\</span><span>@SEQ2</span> <span>);</span>  <span># ref to array of arrays</span>
    <span>my</span> <span>$css_str_ref</span> <span>=</span> <span>CSS_Sorted</span><span>(</span> <span>$STR1</span><span>,</span> <span>$STR2</span> <span>);</span>    <span># ref to array of strings<br /><br /><br /><br /></span></pre><p>There are many different modules on CPAN for calculating the edit distance between two strings. Here's just a selection.</p><p><a href="http://search.cpan.org/perldoc?Text%3A%3ALevenshteinXS">Text::LevenshteinXS</a>&nbsp;and&nbsp;<a href="http://search.cpan.org/perldoc?Text%3A%3ALevenshtein%3A%3AXS">Text::Levenshtein::XS</a>&nbsp;are both versions of the Levenshtein algorithm that require a C compiler, but will be a lot faster than this module.</p><p>The Damerau-Levenshtein edit distance is like the Levenshtein distance, but in addition to insertion, deletion and substitution, it also considers the transposition of two adjacent characters to be a single edit. The module&nbsp;<a href="http://search.cpan.org/perldoc?Text%3A%3ALevenshtein%3A%3ADamerau">Text::Levenshtein::Damerau</a>&nbsp;defaults to using a pure perl implementation, but if you've installed&nbsp;<a href="http://search.cpan.org/perldoc?Text%3A%3ALevenshtein%3A%3ADamerau%3A%3AXS">Text::Levenshtein::Damerau::XS</a>&nbsp;then it will be a lot quicker.</p><p><a href="http://search.cpan.org/perldoc?Text%3A%3AWagnerFischer">Text::WagnerFischer</a>&nbsp;is an implementation of the Wagner-Fischer edit distance, which is similar to the Levenshtein, but applies different weights to each edit type.</p><p><a href="http://search.cpan.org/perldoc?Text%3A%3ABrew">Text::Brew</a>&nbsp;is an implementation of the Brew edit distance, which is another algorithm based on edit weights.</p><p><a href="http://search.cpan.org/perldoc?Text%3A%3AFuzzy">Text::Fuzzy</a>&nbsp;provides a number of operations for partial or fuzzy matching of text based on edit distance.&nbsp;<a href="http://search.cpan.org/perldoc?Text%3A%3AFuzzy%3A%3APP">Text::Fuzzy::PP</a>&nbsp;is a pure perl implementation of the same interface.</p><p><a href="http://search.cpan.org/perldoc?String%3A%3ASimilarity">String::Similarity</a>&nbsp;takes two strings and returns a value between 0 (meaning entirely different) and 1 (meaning identical). Apparently based on edit distance.</p><p><a href="http://search.cpan.org/perldoc?Text%3A%3ADice">Text::Dice</a>&nbsp;calculates&nbsp;<a href="https://en.wikipedia.org/wiki/S%C3%B8rensen%E2%80%93Dice_coefficient">Dice's coefficient</a>&nbsp;for two strings. This formula was originally developed to measure the similarity of two different populations in ecological research.</p><pre><span>&nbsp;</span></pre>]]></description>
	<dc:creator>Neel</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40937/shinycircos-an-rshiny-application-for-interactive-creation-of-circos-plot</guid>
	<pubDate>Fri, 07 Feb 2020 03:26:58 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40937/shinycircos-an-rshiny-application-for-interactive-creation-of-circos-plot</link>
	<title><![CDATA[shinyCircos: an R/Shiny application for interactive creation of Circos plot]]></title>
	<description><![CDATA[<p><span>shinyCircos, a graphical user interface for interactive creation of Circos plot. shinyCircos can be easily installed either on computers for personal use or on local or public servers to provide online use to the community. Furthermore, various types of Circos plots could be easily generated and decorated with simple mouse-click.</span></p>
<p>Tutorial&nbsp;<a href="http://shinycircos.ncpgr.cn/shinyCircos_Help_Manual.pdf">http://shinycircos.ncpgr.cn/shinyCircos_Help_Manual.pdf</a></p>
<p>Github&nbsp;<a href="https://github.com/venyao/shinyCircos">https://github.com/venyao/shinyCircos</a></p><p>Address of the bookmark: <a href="http://150.109.59.144:3838/shinyCircos/" rel="nofollow">http://150.109.59.144:3838/shinyCircos/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44559/metagraph-ultra-scalable-framework-for-dna-search-alignment-assembly</guid>
	<pubDate>Sat, 08 Jun 2024 16:15:25 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44559/metagraph-ultra-scalable-framework-for-dna-search-alignment-assembly</link>
	<title><![CDATA[MetaGraph: Ultra Scalable Framework for DNA Search, Alignment, Assembly]]></title>
	<description><![CDATA[<p><span>The MetaGraph framework</span><span>&nbsp;is designed to work with a wide range of input data sets, indexing from a few samples up to the contents of entire archives with hundreds of thousands of records. The indexing workflow always follows the same principle, transforming single input samples into error-removed, refined sample graphs, which are then merged into a joint metagraph index. Each input sample is annotated in the joint index as a subgraph. This graph index enriched with metadata can then be used for downstream applications such as&nbsp;</span><a href="https://metagraph.ethz.ch/#query">sequence search</a><span>&nbsp;or&nbsp;</span><a href="https://metagraph.ethz.ch/#assembly">differential assembly</a><span>.</span></p>
<p><span>Searcg link&nbsp;https://metagraph.ethz.ch/search&nbsp;</span></p>
<p><span>Pre-print&nbsp;https://www.biorxiv.org/content/10.1101/2020.10.01.322164v4&nbsp;</span></p><p>Address of the bookmark: <a href="https://metagraph.ethz.ch/" rel="nofollow">https://metagraph.ethz.ch/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36015/repeat-aware-repeat-aware-scaffolding-evaluation-framework-by-igor-mandric</guid>
	<pubDate>Wed, 21 Mar 2018 18:10:00 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36015/repeat-aware-repeat-aware-scaffolding-evaluation-framework-by-igor-mandric</link>
	<title><![CDATA[repeat-aware: Repeat aware scaffolding evaluation framework by Igor Mandric]]></title>
	<description><![CDATA[<p>Genome scaffolding is a classical challenging problem in bioinformatics. It refers to joining assembly contigs into chains (called scaffolds). The join between two contigs A and B is considered correct if:</p>
<ul>
<li>Their relative orientation is correct</li>
<li>Their relative order is correct</li>
<li>The gap estimate is similar to the true distance on the reference</li>
</ul>
<p>The problem of scaffolding validation is also a challenging one. One of the main issues which hinders from an adequate scaffolding evaluation are genome repeats. The previous standard for evaluation&nbsp;<a href="https://genomebiology.biomedcentral.com/articles/10.1186/gb-2014-15-3-r42">(Hunt et al.,&nbsp;<em>Genome Biology</em>, 2014)</a>&nbsp;did not take into account repeats. In this evaluation framework, repeats are taken into account.</p>
<p style="text-align: center;"><a href="https://camo.githubusercontent.com/9675b90205e5bc0dc0b6b84b321b00bc87d8d88e/687474703a2f2f616c616e2e63732e6773752e6564752f7265706561742d61776172652f6669677572652e706e67" target="_blank"><img src="https://camo.githubusercontent.com/9675b90205e5bc0dc0b6b84b321b00bc87d8d88e/687474703a2f2f616c616e2e63732e6773752e6564752f7265706561742d61776172652f6669677572652e706e67" width="75%" alt="image" style="border: 0px;"></a></p>
<p>The new evaluation framework considers the optimal assignment of contigs in the output scaffolding to contigs in the reference scaffolding in the sense of the number of correct links.</p>
<p>&nbsp;</p>
<p>https://github.com/mandricigor/repeat-aware</p><p>Address of the bookmark: <a href="https://github.com/mandricigor/repeat-aware" rel="nofollow">https://github.com/mandricigor/repeat-aware</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38829/nquire-a-statistical-framework-for-ploidy-estimation-using-ngs-short-read-data</guid>
	<pubDate>Thu, 31 Jan 2019 05:12:19 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38829/nquire-a-statistical-framework-for-ploidy-estimation-using-ngs-short-read-data</link>
	<title><![CDATA[nQuire: A statistical framework for ploidy estimation using NGS short-read data]]></title>
	<description><![CDATA[<p>nQuire implements a set of commands to estimate ploidy level of individuals from species, where recent polyploidization occurred and intraspecific ploidy variation is observed. Specifically, nQuire uses next-generation sequencing data to distinguish between diploids, triploids and tetraploids, on the basis of frequency distributions at variant sites where only two bases are segregating.</p>
<p>For more background see also the publication at&nbsp;<a href="https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-018-2128-z">BMC Bioinformatics</a>.</p>
<p>https://github.com/clwgg/nQuire</p><p>Address of the bookmark: <a href="https://github.com/clwgg/nQuire" rel="nofollow">https://github.com/clwgg/nQuire</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44481/unialigner-a-parameter-free-framework-for-fast-sequence-alignment</guid>
	<pubDate>Fri, 08 Mar 2024 23:36:12 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44481/unialigner-a-parameter-free-framework-for-fast-sequence-alignment</link>
	<title><![CDATA[UniAligner: a parameter-free framework for fast sequence alignment]]></title>
	<description><![CDATA[<p>UniAligner (formerly, TandemAligner) is the first parameter-free algorithm for sequence alignment that introduces a sequence-dependent alignment scoring that automatically changes for any pair of compared sequences. Classical alignment approaches, such as the Smith-Waterman algorithm, that work well for most sequences, fail to construct biologically adequate alignments of extra-long tandem repeats (ETRs), such as human centromeres and immunoglobulin loci. This limitation was overlooked in the previous studies since the sequences of the centromeres and other ETRs across multiple genomes only became available recently.</p>
<p>More at https://www.nature.com/articles/s41592-023-01970-4</p><p>Address of the bookmark: <a href="https://github.com/seryrzu/unialigner" rel="nofollow">https://github.com/seryrzu/unialigner</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36368/d3-javascript-for-visualization</guid>
	<pubDate>Mon, 23 Apr 2018 08:42:22 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36368/d3-javascript-for-visualization</link>
	<title><![CDATA[D3 javascript for visualization !]]></title>
	<description><![CDATA[<p><span>Welcome to the&nbsp;</span><span>D3 gallery</span><span>! More examples are available on&nbsp;</span><a href="http://bl.ocks.org/mbostock">bl.ocks.org/mbostock</a><span>. If you want to share an example and don't have your own hosting, consider using&nbsp;</span><a href="http://gist.github.com/">Gist</a><span>&nbsp;and&nbsp;</span><a href="http://bl.ocks.org/">bl.ocks.org</a><span>. If you want to share or view live examples try&nbsp;</span><a href="https://vida.io/explore">vida.io</a><span>.</span></p><p>Address of the bookmark: <a href="https://github.com/d3/d3/wiki/Gallery" rel="nofollow">https://github.com/d3/d3/wiki/Gallery</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/140/python-education-material</guid>
	<pubDate>Wed, 10 Jul 2013 16:38:23 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/140/python-education-material</link>
	<title><![CDATA[Python Education Material]]></title>
	<description><![CDATA[<p><span>Google provide free class for people with a little bit of programming experience who want to learn Python. The google python class includes written materials, lecture videos, and lots of code exercises to practice Python coding. These materials are used within Google to introduce Python to people who have just a little programming experience.</span></p><p><span>Find more @&nbsp;<a href="https://developers.google.com/edu/python/">https://developers.google.com/edu/python/</a></span></p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
</item>

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