BOL: Related items

MATHomics Lab

Tue, 19 Nov 2013 18:17:32 -0600

Mathomics is a collaborative research group of the Center for Mathematical Modeling and the Center for Genome Regulation at University of Chile, created to play a central role in the development of biotechnological projects, providing state of the art bioinformatics and mathematical modeling tools, allowing to face these problems from the point of view of Systems Biology.

Lab page @ http://www.mathomics.cl/

Nieduszynski Group

Fri, 26 Sep 2014 19:35:06 -0500

Complete, accurate replication of the genome is essential for life. All chromosomes in eukaryotic cells must be duplicated and then segregated to daughter cells to ensure genetic integrity and produce the large number of cells that make up a multicellular organism. We are using genetic, genomic and computational methods to understand how chromosome replication is regulated to ensure genome stability. By focusing on the basic biology that underpins cell growth and division we aim to provide new insights that may help our understanding of diseases such as cancer and congenital disorders.

More http://www.nieduszynski.org/index.php
http://www.path.ox.ac.uk/research/cell-biology-and-pathology/conrad-nieduszynski-group

BUSCO

Jitendra Narayan — Sun, 07 Feb 2016 16:02:39 -0600

Assessing genome assembly and annotation completeness with Benchmarking Universal Single-Copy Orthologs

More at http://busco.ezlab.org/

Address of the bookmark: http://busco.ezlab.org/

Bioinformatician - Purdue Cancer Center

Wed, 03 Feb 2021 22:54:14 -0600

The Center for Cancer Research is an NCI-designated cancer center. The center is a catalyst for collaborative cancer research around Purdue University. In this role, the selected individual will have the opportunity to cooperate with Purdue faculty and students in performing cutting-edge research and analyses, with opportunities for professional development, and the possibility of co-authorship in faculty research publications.
Projects will be challenging, including various model organisms, and we are looking for an individual who is excited about interacting with multi-disciplinary cancer research groups and the development of new tools, techniques, and workflows. Independently perform both routine and project-specific analyses, advise faculty on the design of experiments, writing manuscripts for publication, and writing grant proposals. Interact and collaborate with bioinformatics services (i.e. Statistical Consulting Center to provide relevant services to the campus research community), where applicable. Support all of the bioinformatics activities of the Center for Cancer Research at Purdue University
Required:

Master's degree in bioinformatics, computer science, molecular biology, or related field
One year of experience in analyzing RNA-Seq data
In lieu of a degree, consideration will be given to an equivalent combination of related education and required work experience.
Understanding of molecular biology, biochemistry, and genetics
Proficiency in writing scripts using Perl, Python, Java, or equivalent languages
Proficiency in R and UNIX/LINUX
Knowledge of genomics, alignment, annotation, bioinformatics, concepts of sequence assembly
Highly motivated and detail-oriented
Ability, interest, and curiosity to learn new skills
Must possess strong communication skills to work effectively with users across disciplines
Ability to work independently and as part of a multi-disciplinary team
Strong visual, verbal, and written communication skills
Excellent time organizational skills
Preferred:

Experience writing software or building software pipelines
Experience with oncology-specific public databases including TCGA
Experience with deploying and/or running software on high-performance computational systems
Statistical and experimental design knowledge
Additional Information:

This position is contingent on the availability of funding
Purdue will not sponsor employment authorization for this position
A background check will be required for employment in this position
FLSA: Exempt (Not Eligible For Overtime)
Retirement Eligibility: Defined Contribution Waiting Period
Purdue University is an EOE/AA employer. All individuals, including minorities, women, individuals with disabilities, and veterans are encouraged to apply

More at https://careers.purdue.edu/job/West-Lafayette-Bioinformatician-Purdue-Cancer-Center-IN-47906/686617600/

PhD position in Molecular Cell Biology

Sat, 15 Feb 2020 06:09:55 -0600

https://www.jobvector.de/jobs-stellenangebote/biologie-life-sciences/wissenschaftliche-r-mitarbeiter-in/phd-position-molecular-cell-biology-129604.html?suid=0ec057818886c1eceac674ca3f83943367a6cbe2

Essential experience / qualifications:
We are looking for highly motivated candidates holding a Master / Diploma in Biology, Biochemistry, Molecular Medicine or similar; solid knowledge of molecular and cell biological techniques; good English knowledge.

Applications:
Please send your application (including CV, letter of motivation, contact information of two references, and list of publication) by 13.03.2020 at the latest to:

Universitätsklinikum Erlangen
Chirurgische Klinik
Translational Research Center
Prof. Dr. rer. nat. Michael Stürzl
Schwabachanlage 12
91054 Erlangen
E-Mail: michael.stuerzl@uk-erlangen.de

SocBiN Bioinformatics 2014

Tue, 03 Sep 2013 18:50:20 -0500

14th annual conference in Bioinformatics

Date : June 10-13

Organizers: The Society for Bioinformatics in Northern European countries (SocBiN) and the Norwegian Bioinformatics Platform / ELIXIR.NO

Venue: Department of Informatics, University of Oslo, Norway

Topics:
Tools and technologies for integrative bioinformatics
Metagenomics
Comparative genomics and phylogeny
Post-ENCODE bioinformatics
Gene regulation
Cancer genomes
Marine genomics

List of cancer genomics research web resources !

biogeek — Wed, 27 Dec 2017 20:33:09 -0600

Major web resources for cancer genomics research

CGHub
https://cghub.ucsc.edu/
Comprehensive data repository; huge data size

EGA
https://www.ebi.ac.uk/ega/
Comprehensive data repository; huge data size

COSMIC
http://cancer.sanger.ac.uk
Largest somatic mutation database; genome sequencing paper curation

CPRG
http://www.broadinstitute.org/software/cprg
Interface for cancer program resources

GDAC
http://gdac.broadinstitute.org/
Data analysis; automatic pipelines; user-friendly reports

SNP500Cancer
http://snp500cancer.nci.nih.gov
Sequence and genotype verification of SNPs

canEvolve
www.canevolve.org/
Comprehensive analysis of tumor profile; Data from 90 studies involving more than 10,000 patients

MethyCancer
http://methycancer.psych.ac.cn
Relationship among DNA methylation, gene expression and cancer

SomamiR
http://compbio.uthsc.edu/SomamiR/
Correlation between somatic mutation and microRNA; genome-wide displaying

cBioPortal
http://www.cbioportal.org/public-portal/
Graphical summaries; gene alteration; processed data; visualization

UCSC Cancer Genomics Browser
https://genome-cancer.soe.ucsc.edu/
Clinical information; gene expression; copy number variation; visualization

CGWB
https://cgwb.nci.nih.gov/
Visualization; gene mutation and variation; automated analysis pipeline

GDSC
http://www.cancerrxgene.org
Drug sensitivity information; drug response information

canSAR
https://cansar.icr.ac.uk/
Multidisciplinary information; drug discovery

NONCODE
http://www.noncode.org/ ncRNAs;
lncRNAs; up-to-date and comprehensive resource

Multiple PhD positions

Sun, 09 Feb 2020 03:10:28 -0600

14 PhD positions in the EU Horizon 2020 Marie Skłodowska-Curie Project PRECODE:
International training network which sets a joint research programme to train a new generation of leading scientists in model systems and methods for the development of new therapies for pancreatic cancer (PaCa)

http://precode-project.eu/jobs-board/#1572451761376-39d75f63-c6fb

COPE: an accurate k-mer-based pair-end reads connection tool to facilitate genome assembly

Jit — Wed, 06 Dec 2017 02:08:14 -0600

An efficient tool called Connecting Overlapped Pair-End (COPE) reads, to connect overlapping pair-end reads using k-mer frequencies. We evaluated our tool on 30× simulated pair-end reads from Arabidopsis thaliana with 1% base error. COPE connected over 99% of reads with 98.8% accuracy, which is, respectively, 10 and 2% higher than the recently published tool FLASH. When COPE is applied to real reads for genome assembly, the resulting contigs are found to have fewer errors and give a 14-fold improvement in the N50 measurement when compared with the contigs produced using unconnected reads.

Address of the bookmark: ftp://ftp.genomics.org.cn/pub/cope

minialign: fast and accurate alignment tool for PacBio and Nanopore long reads

Jit — Thu, 24 May 2018 08:33:26 -0500

Minialign is a little bit fast and moderately accurate nucleotide sequence alignment tool designed for PacBio and Nanopore long reads. It is built on three key algorithms, minimizer-based index of the minimap overlapper, array-based seed chaining, and SIMD-parallel Smith-Waterman-Gotoh extension.

Address of the bookmark: https://github.com/ocxtal/minialign