<?xml version='1.0'?><rss version="2.0" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:georss="http://www.georss.org/georss" xmlns:atom="http://www.w3.org/2005/Atom" >
<channel>
	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/42359?offset=360</link>
	<atom:link href="https://bioinformaticsonline.com/related/42359?offset=360" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34386/slidesort-bpr</guid>
	<pubDate>Mon, 20 Nov 2017 09:19:52 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34386/slidesort-bpr</link>
	<title><![CDATA[SLIDESORT-BPR]]></title>
	<description><![CDATA[<p>Chromosomal rearrangement events are caused by abnormal breaking and rejoining of DNA molecules. They are responsible for many of the cancer related diseases. Detecting the DNA breaking and repairing mechanism, therefore, may offer vital clues about the pathologic causes and diagnostic/therapeutic target of these diseases. But this effort also poses considerable challenges, because the structural variations and the genomes are different from one person to another. Intermediate comparison via reference genome could lead to the loss information. Unlike the current methods which make use the reference genome, we developed a method to detect the breakpoint reads directly from observing the differences between two (or more) NGS short reads samples. Slidesort-BPR is a command line tool implemented in C++.</p><p>Address of the bookmark: <a href="https://github.com/ewijaya/slidesort-bpr" rel="nofollow">https://github.com/ewijaya/slidesort-bpr</a></p>]]></description>
	<dc:creator>Abhimanyu Singh</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34914/ra-assembler-a-de-novo-dna-assembler-for-third-generation-sequencing-data</guid>
	<pubDate>Wed, 27 Dec 2017 20:36:54 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34914/ra-assembler-a-de-novo-dna-assembler-for-third-generation-sequencing-data</link>
	<title><![CDATA[Ra assembler - a de novo DNA assembler for third generation sequencing data]]></title>
	<description><![CDATA[<p>Integration of the Ra assembler - a de novo DNA assembler for third generation sequencing data developed on Faculty of Electrical Engineering and Computing (FER), Ruder Boskovic Institute (RBI) and Genome Institute of Singapore (GIS).</p>
<p>Ra is in development since 2014 in the form of several separate components that used to be run individually.<br>This project aims to ease the usage of Ra by integrating it into a complete de novo assembly tool.</p>
<p>Unlike other state-of-the-art assemblers,&nbsp;<span>Ra does not have an error correction step.</span>&nbsp;Instead, it relies on detecting overlaps using a very sensitive and specific overlapper ("graphmap -w owler",&nbsp;<a href="https://github.com/isovic/graphmap">https://github.com/isovic/graphmap</a>) and constructing and reducing an overlap graph (Ra layout,&nbsp;<a href="https://github.com/mariokostelac/ra">https://github.com/mariokostelac/ra</a>).</p><p>Address of the bookmark: <a href="https://github.com/mariokostelac/ra-integrate/" rel="nofollow">https://github.com/mariokostelac/ra-integrate/</a></p>]]></description>
	<dc:creator>biogeek</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/36607/tarean-a-computational-tool-for-identification-and-characterization-of-satellite-dna-from-unassembled-short-reads</guid>
	<pubDate>Tue, 15 May 2018 02:53:11 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/36607/tarean-a-computational-tool-for-identification-and-characterization-of-satellite-dna-from-unassembled-short-reads</link>
	<title><![CDATA[TAREAN: A computational tool for identification and characterization of satellite DNA from unassembled short reads]]></title>
	<description><![CDATA[<p><strong>TA</strong>ndem&nbsp;<strong>RE</strong>peat&nbsp;<strong>AN</strong>alyzer -TAREAN &ndash; is a computational pipeline for&nbsp;<strong>unsupervised identification of satellite repeats</strong>&nbsp;from unassembled sequence reads. The pipeline uses low-pass whole genome sequence reads and performs their graph-based clustering. Resulting clusters, representing all types of repeats, are then examined for the presence of circular structures and putative satellite repeats are reported.</p>
<p><em><strong>How to use TAREAN</strong></em>:</p>
<ul>
<li>Install a local instance of the pipeline using its source code available from&nbsp;<a href="https://bitbucket.org/petrnovak/repex_tarean" target="_blank" title="TAREAN source code">bitbucket repository</a>.</li>
<li>Use&nbsp; public Galaxy-based server at&nbsp;<a href="https://repeatexplorer-elixir.cerit-sc.cz/" target="_blank">https://repeatexplorer-elixir.cerit-sc.cz/</a>. The server is provided in frame of the&nbsp;<a href="https://www.elixir-czech.cz/" target="_blank">Elixir CZ project</a>&nbsp;and is maintained by&nbsp;<a href="https://www.cesnet.cz/" target="_blank">CESNET</a>&nbsp;and&nbsp;<a href="https://www.cerit-sc.cz/en/index.html" target="_blank">CERIT-SC</a>. Simple registration is required to use this service.</li>
</ul>
<p>Development of TAREAN was supported by&nbsp;<a href="https://www.elixir-czech.cz/" target="_blank" title="ELIXIR-CZ">ELIXIR CZ</a>&nbsp;research infrastructure project (MEYS Grant No: LM2015047).</p>
<p><strong><em>References</em></strong></p>
<p>Novak, P., Avila Robledillo, L., Koblizkova, A., Vrbova, I., Neumann, P., Macas, J. (2017) &ndash;&nbsp;<a href="https://academic.oup.com/nar/article/3574061/" target="_blank">TAREAN: a computational tool for identification and characterization of satellite DNA from unassembled short reads</a>.&nbsp;<em>Nucleic Acids Res.</em>, doi:10.1093/nar/gkx257</p><p>Address of the bookmark: <a href="https://bitbucket.org/petrnovak/repex_tarean" rel="nofollow">https://bitbucket.org/petrnovak/repex_tarean</a></p>]]></description>
	<dc:creator>Surabhi Chaudhary</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37987/ropebwt2-incremental-construction-of-fm-index-for-dna-sequences</guid>
	<pubDate>Thu, 25 Oct 2018 04:48:54 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37987/ropebwt2-incremental-construction-of-fm-index-for-dna-sequences</link>
	<title><![CDATA[RopeBWT2: Incremental construction of FM-index for DNA sequences]]></title>
	<description><![CDATA[<p><span>RopeBWT2 is an tool for constructing the FM-index for a collection of DNA sequences. It works by incrementally inserting one or multiple sequences into an existing pseudo-BWT position by position, starting from the end of the sequences. This algorithm can be largely considered a mixture of&nbsp;</span><a href="http://dx.doi.org/10.1007/978-3-642-21458-5_20">BCR</a><span>&nbsp;and&nbsp;</span><a href="http://dfmi.sourceforge.net/">dynamic FM-index</a><span>. Nonetheless, ropeBWT2 is unique in that it may&nbsp;</span><em>implicitly</em><span>sort the input into reverse lexicographical order (RLO) or reverse-complement lexicographical order (RCLO) while building the index.</span></p><p>Address of the bookmark: <a href="https://github.com/lh3/ropebwt2" rel="nofollow">https://github.com/lh3/ropebwt2</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40856/3d-de-novo-assembly-3d-dna-pipeline</guid>
	<pubDate>Sun, 02 Feb 2020 13:41:55 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40856/3d-de-novo-assembly-3d-dna-pipeline</link>
	<title><![CDATA[3D de novo assembly (3D DNA) pipeline]]></title>
	<description><![CDATA[<p>For a detailed description of the pipeline and how it integrates with other tools designed by the Aiden Lab see&nbsp;<a href="http://aidenlab.org/assembly/manual_180322.pdf">Genome Assembly Cookbook</a>&nbsp;on&nbsp;<a href="http://aidenlab.org/assembly">http://aidenlab.org/assembly</a>.</p>
<p>For the original version of the pipeline and to reproduce the Hs2-HiC and the AaegL4 genomes reported in&nbsp;<a href="http://science.sciencemag.org/content/356/6333/92">(Dudchenko et al.,&nbsp;<em>Science</em>, 2017)</a>&nbsp;see the&nbsp;<a href="https://github.com/theaidenlab/3d-dna/tree/745779bdf64db6e55bddb70c24e9b58825938c33">original commit</a>.</p>
<p>For the detailed description of the merge section see&nbsp;<a href="https://github.com/theaidenlab/AGWG-merge">https://github.com/theaidenlab/AGWG-merge</a>.</p><p>Address of the bookmark: <a href="https://github.com/theaidenlab/3d-dna" rel="nofollow">https://github.com/theaidenlab/3d-dna</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/42023/encode3-a-collection-of-research-articles-and-related-content-describing-the-encyclopedia-of-dna-elements-its-datasets-and-tools</guid>
	<pubDate>Sat, 08 Aug 2020 08:25:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/42023/encode3-a-collection-of-research-articles-and-related-content-describing-the-encyclopedia-of-dna-elements-its-datasets-and-tools</link>
	<title><![CDATA[ENCODE3: A collection of research articles and related content describing the Encyclopedia of DNA Elements, its datasets and tools.]]></title>
	<description><![CDATA[<p>How cells, tissues and organisms interpret the information encoded in the genome has vital implications for our understanding of development, health and disease. Launched in 2003, the ENCyclopedia Of DNA Elements (ENCODE) project has the aim of mapping the functional elements in the human genome (later expanded to include model organisms).</p><p>During the first phase of ENCODE, published in 2007, microarray-based technologies were used to detect regions associated with transcription factors, certain histone modifications and open chromatin within a pre-specified 1% of the human genome.</p><p>ENCODE&rsquo;s second phase saw a switch to sequencing-based technologies, the addition of new assay types and the analysis of functional elements genome-wide, described in a collection of research articles in 2012.</p><p><span>The&nbsp;</span><a href="https://www.nature.com/articles/s41586-020-2493-4">Encyclopedia paper of ENCODE 3</a><span>, published in&nbsp;</span><em>Nature</em><span>, gives an overview of the various assays that were performed in human and mouse cell lines and tissues and describes a Registry of human and mouse candidate&nbsp;</span><em>cis</em><span>-regulatory elements (cCREs).</span></p><p>More at&nbsp;<a href="https://www.nature.com/immersive/d42859-020-00027-2/index.html">https://www.nature.com/immersive/d42859-020-00027-2/index.html</a></p>]]></description>
	<dc:creator>Shruti Paniwala</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44559/metagraph-ultra-scalable-framework-for-dna-search-alignment-assembly</guid>
	<pubDate>Sat, 08 Jun 2024 16:15:25 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44559/metagraph-ultra-scalable-framework-for-dna-search-alignment-assembly</link>
	<title><![CDATA[MetaGraph: Ultra Scalable Framework for DNA Search, Alignment, Assembly]]></title>
	<description><![CDATA[<p><span>The MetaGraph framework</span><span>&nbsp;is designed to work with a wide range of input data sets, indexing from a few samples up to the contents of entire archives with hundreds of thousands of records. The indexing workflow always follows the same principle, transforming single input samples into error-removed, refined sample graphs, which are then merged into a joint metagraph index. Each input sample is annotated in the joint index as a subgraph. This graph index enriched with metadata can then be used for downstream applications such as&nbsp;</span><a href="https://metagraph.ethz.ch/#query">sequence search</a><span>&nbsp;or&nbsp;</span><a href="https://metagraph.ethz.ch/#assembly">differential assembly</a><span>.</span></p>
<p><span>Searcg link&nbsp;https://metagraph.ethz.ch/search&nbsp;</span></p>
<p><span>Pre-print&nbsp;https://www.biorxiv.org/content/10.1101/2020.10.01.322164v4&nbsp;</span></p><p>Address of the bookmark: <a href="https://metagraph.ethz.ch/" rel="nofollow">https://metagraph.ethz.ch/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40994/biological-databases</guid>
	<pubDate>Wed, 12 Feb 2020 01:16:29 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40994/biological-databases</link>
	<title><![CDATA[Biological databases !]]></title>
	<description><![CDATA[<p>Now a days there are a lots of genomics databases available around the world. This bookmark is created to provide all links in one place ...</p>
<p>ftp://ftp.ncbi.nih.gov/genomes/</p>
<p>https://hgdownload.soe.ucsc.edu/downloads.html</p><p>Address of the bookmark: <a href="ftp://ftp.ncbi.nih.gov/genomes/" rel="nofollow">ftp://ftp.ncbi.nih.gov/genomes/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/21241/pacman</guid>
	<pubDate>Mon, 16 Feb 2015 12:15:17 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/21241/pacman</link>
	<title><![CDATA[Pacman]]></title>
	<description><![CDATA[<p><span>The pacman package is an R package management tool that combines the functionality of base library related functions into intuitively named functions. This package is ideally added to .Rprofile to increase workflow by reducing time recalling obscurely named functions, reducing code and integrating functionality of base functions to simultaneously perform multiple actions.<br /><br />Function names in the pacman package follow the format of p_xxx where &lsquo;xxx&rsquo; is the task the function performs. For instance the p_load function allows the user to load one or more packages as a more generic substitute for the library or require functions and if the package isn&rsquo;t available locally it will install it for you.<br /><br /></span></p><p><strong>Installation</strong></p><p><span>To download the development version of pacman:</span></p><p><span>Download the </span><a href="https://github.com/trinker/pacman/zipball/master">zip ball</a><span> or </span><a href="https://github.com/trinker/pacman/tarball/master">tar ball</a><span>, decompress and run </span><code>R CMD INSTALL</code><span> on it, or use th</span><span>e </span><strong>devtools</strong><span> package to install the development version:</span></p><pre title="">## Make sure your current packages are up to date
update.packages()
## devtools is required
devtools::install_github("trinker/pacman")
</pre><p>Note: Windows users need <a href="http://www.murdoch-sutherland.com/Rtools/">Rtools</a> and <a href="http://CRAN.R-project.org/package=devtools">devtools</a> to install this way.</p><p>More at https://github.com/trinker/pacman</p><p>&nbsp;</p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27850/clusterprofiler</guid>
	<pubDate>Thu, 16 Jun 2016 18:57:03 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27850/clusterprofiler</link>
	<title><![CDATA[clusterProfiler]]></title>
	<description><![CDATA[<p>statistical analysis and visulization of functional profiles for genes and gene clusters<br><br>Bioconductor version: Release (3.3)<br><br>This package implements methods to analyze and visualize functional profiles (GO and KEGG) of gene and gene clusters.<br><br>Author: Guangchuang Yu &lt;guangchuangyu at gmail.com&gt; with contributions from Li-Gen Wang and Giovanni Dall'Olio.<br><br>Maintainer: Guangchuang Yu &lt;guangchuangyu at gmail.com&gt;<br><br>Citation (from within R, enter citation("clusterProfiler")):<br><br>Yu G, Wang L, Han Y and He Q (2012). &ldquo;clusterProfiler: an R package for comparing biological themes among gene clusters.&rdquo; OMICS: A Journal of Integrative Biology, 16(5), pp. 284-287.<br>Installation<br><br>To install this package, start R and enter:<br><br>## try http:// if https:// URLs are not supported<br>source("https://bioconductor.org/biocLite.R")<br>biocLite("clusterProfiler")</p>
<p>https://www.bioconductor.org/packages/devel/bioc/vignettes/clusterProfiler/inst/doc/clusterProfiler.html</p><p>Address of the bookmark: <a href="https://www.bioconductor.org/packages/devel/bioc/vignettes/clusterProfiler/inst/doc/clusterProfiler.html" rel="nofollow">https://www.bioconductor.org/packages/devel/bioc/vignettes/clusterProfiler/inst/doc/clusterProfiler.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

</channel>
</rss>