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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/42806?offset=160</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/37586/julia-programming-language-a-python-and-r-rival</guid>
	<pubDate>Sat, 25 Aug 2018 04:46:39 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/37586/julia-programming-language-a-python-and-r-rival</link>
	<title><![CDATA[Julia Programming Language, a Python and R rival]]></title>
	<description><![CDATA[<p>Big data has grown to become one of the most lucrative fields. In fact, data scientists are some of the most sought people. They are usually hired to analyze, control and parse large chunks of data. Implementing these actions using traditional techniques is not a walk in the park. This is why most data scientists prefer using programming languages such as R and Python. However, there is one more programming language that can do the job. That is Julia programming language.</p><p>What Is Julia Language?</p><p>Julia is a programming language that came into the limelight in 2012. It is a general-purpose programming language that was designed for solving scientific computations. Julia was meant to be an alternative to Python, R and other programming languages that were mainly used for manipulating data. This is because it has numerous features that can minimize the complexities of numerical computations.&nbsp;</p><p>Julia optimizes on the best features of Python and R while at the same time overlooks their weaknesses. This explains why it is viewed as an alternative to these programming languages. For instance, it utilizes the readability and simplicity of Python then performs faster.</p><p>Julia is the most preferred programming language for data scientists and mathematicians. This is because its core features are similar to the ones that are used on most data software. Also, the language is ideal for these two subjects because its syntax is similar to the standard mathematical formulas.</p><p>Key Features Of Julia Language<br />Uses JIT Compilation<br />Parallelism<br />Dynamic Typing<br />Simple Syntax<br />Allows Metaprogramming<br />Accessible to Libraries<br />-1-Array Indexing</p><p>Julia Vs Python And R Programming Languages<br />1. Speed<br />Julia is faster than both Python and R. This is a very critical aspect that is given special attention in the big data programming. The high speed of Julia is because of JIT compilers. You will need to install external libraries on Python to achieve similar speed.</p><p>2. Syntax<br />Julia has a math-friendly syntax. The syntax of this programming language is similar to the mathematical formulas hence can be used to perform mathematical and scientific computations. This syntax makes it easier to learn than Python.</p><p>3. Parallelism<br />Although both Python and R use parallelism, Julia uses a top-level parallelism. Julia allows the processor to perform to the optimum level than what Python and R can achieve.</p><p>4. Versatility<br />Julia programming language is more versatile than Python and R. It allows a programmer to move from different codes and functions with ease.</p><p>The only area that Python and R are superior to Julia is in terms of community. Given that Julia is a new programming language, it has a small community as compared to others which have been around for years.</p><p>In overall Julia programming language is a better alternative that you can use to handle Big data projects. Despite having a small community, it is one of those programming languages that you can easily learn.</p>]]></description>
	<dc:creator>Radha Agarkar</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38634/eyechrom-visualizing-chromosome-count-data-from-plants</guid>
	<pubDate>Tue, 08 Jan 2019 10:20:54 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38634/eyechrom-visualizing-chromosome-count-data-from-plants</link>
	<title><![CDATA[EyeChrom: Visualizing Chromosome Count Data From Plants]]></title>
	<description><![CDATA[<p><span>It's goal is to show chromosmal data per genus. Select the genus, and the plot will show the records found for it in the Chromosome Counts Database. note: Report an issue via Gihub: github.com/roszenil/CCDBcurator and github.com/RodrigoRivero/EyeChrom</span></p>
<p>https://bsapubs.onlinelibrary.wiley.com/doi/pdf/10.1002/aps3.1207</p><p>Address of the bookmark: <a href="http://eyechrom.com:3838/EyeChrom/" rel="nofollow">http://eyechrom.com:3838/EyeChrom/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/42324/comparative-genomics-data-set-including-240-mammals-released</guid>
	<pubDate>Thu, 19 Nov 2020 06:45:39 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/42324/comparative-genomics-data-set-including-240-mammals-released</link>
	<title><![CDATA[Comparative Genomics Data Set Including 240 Mammals Released !]]></title>
	<description><![CDATA[<p>The genome of 130 mammals was sequenced by a large international consortium and the data was analyzed together with 110 existing genomes to allow scientists to identify the important positions in the DNA. This report, published in Nature today will help advance research on human disease mutations and inform how best to protect endangered species.</p><p>In addition to the knowledge of the human genome, all these genomes, widely sampled across mammals, can be used to research how particular organisms respond to different conditions. Some otters, for example, have a thick, water-resistant shell, and some rodents, but not all, have adapted to hibernation. These animal traits will help us to understand human traits, such as metabolic diseases.</p><p><img src="https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41586-020-2876-6/MediaObjects/41586_2020_2876_Fig1_HTML.png?as=webp" alt="image" style="border: 0px; border: 0px;"></p><p>With climate change and more animal ecosystems being threatened by human activity, the protection of endangered species is becoming increasingly important. Scientists have historically researched several people in various populations of a species to understand the genetic variation that occurs in that species. This is important for understanding how particular species can be protected. In this study, animals on the Red List of Endangered Species of the International Union for Conservation of Nature had fewer differences in their genomes, which is consistent with their endangered status.</p><p>Ref @&nbsp;A comparative genomics multitool for scientific discovery and conservation&nbsp;https://www.nature.com/articles/s41586-020-2876-6</p><p>&nbsp;Data at&nbsp;http://zoonomiaproject.org/</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44545/amr-database</guid>
	<pubDate>Tue, 04 Jun 2024 13:37:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44545/amr-database</link>
	<title><![CDATA[AMR Database !]]></title>
	<description><![CDATA[<ul>
<li><a href="http://en.mediterranee-infection.com/article.php?laref=283%26titre=arg-annot">ARG-ANNOT</a>. PMID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/24145532">24145532</a></li>
<li><a href="https://card.mcmaster.ca/">CARD</a>. PMID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/23650175">23650175</a></li>
<li><a href="https://megares.meglab.org/">MEGARes</a>&nbsp;PMID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/27899569">27899569</a></li>
<li><a href="https://www.ncbi.nlm.nih.gov/pathogens/isolates#/refgene/">NCBI</a>&nbsp;BioProject:&nbsp;<a href="https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA313047">PRJNA313047</a></li>
<li><a href="https://cge.cbs.dtu.dk/services/PlasmidFinder/">plasmidfinder</a>&nbsp;PMID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/24777092">24777092</a></li>
<li><a href="https://cge.cbs.dtu.dk//services/ResFinder/">resfinder</a>. PMID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/22782487">22782487</a></li>
<li><a href="http://www.mgc.ac.cn/VFs/">VFDB</a>. PMID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/26578559">26578559</a></li>
<li><a href="https://github.com/katholt/srst2">SRST2</a>'s version of ARG-ANNOT. PMID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/25422674">25422674</a>.</li>
<li><a href="https://cge.cbs.dtu.dk/services/VirulenceFinder/">VirulenceFinder</a>&nbsp;PMID:&nbsp;<a href="http://www.ncbi.nlm.nih.gov/pubmed/24574290">24574290</a>.</li>
</ul><p>Address of the bookmark: <a href="https://github.com/sanger-pathogens/ariba/wiki/Task%3A-getref" rel="nofollow">https://github.com/sanger-pathogens/ariba/wiki/Task%3A-getref</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44852/what-is-data-science-%E2%80%94-a-bioinformatics-perspective</guid>
	<pubDate>Mon, 16 Jun 2025 01:44:34 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44852/what-is-data-science-%E2%80%94-a-bioinformatics-perspective</link>
	<title><![CDATA[What is Data Science? — A Bioinformatics Perspective]]></title>
	<description><![CDATA[<p>In today&rsquo;s era of big biology, we&rsquo;re generating more data than ever before&mdash;genomes, transcriptomes, proteomes, metabolomes, microbiomes&hellip; you name it. But raw biological data doesn&rsquo;t speak for itself. Making sense of it requires more than traditional biology. This is where data science steps in.</p><p><strong>So, What Is Data Science?</strong><br />At its core, data science is the interdisciplinary field that extracts knowledge and insights from data using programming, statistics, and domain expertise. In bioinformatics, data science enables us to turn gigabytes of sequence data into biological meaning.</p><p>Imagine trying to understand gene regulation in cancer by analyzing thousands of RNA-seq samples, or predicting antibiotic resistance from bacterial genomes&mdash;these challenges are not solvable through wet lab experiments alone. They require data-driven thinking.</p><p><strong>Data Science Meets Bioinformatics</strong><br />Bioinformatics is inherently a data science domain. From genomics to systems biology, every field in modern biology relies on data science techniques to:</p><p>Clean and process massive datasets</p><p>Discover patterns in high-dimensional data</p><p>Build predictive models (e.g., for disease classification)</p><p>Visualize complex biological networks and trends</p><p>Integrate diverse data types (e.g., transcriptomic + epigenomic data)</p><p><strong>The Bioinformatics Toolkit</strong><br />Here&rsquo;s what data science typically looks like in bioinformatics:</p><p>Task Data Science Role<br />Sequence alignment Efficient algorithms, indexing, parallel processing<br />Gene expression analysis Statistical modeling (e.g., DESeq2, limma)<br />Variant calling Data filtering, probabilistic models<br />Clustering of cells in single-cell data Unsupervised learning<br />Protein structure prediction Deep learning models (e.g., AlphaFold)<br />Metagenomics Data integration, classification, dimensionality reduction</p><p>Common tools include Python, R, Bioconductor, scikit-learn, Pandas, Seurat, and TensorFlow&mdash;often working together in reproducible workflows.</p><p><strong>It's Not Just About Coding</strong><br />A common misconception is that bioinformatics is just programming or scripting. But being a data scientist in bioinformatics also means:</p><p>Understanding experimental design</p><p>Asking biologically meaningful questions</p><p>Choosing the right statistical or machine learning models</p><p>Communicating findings effectively (e.g., plots, dashboards, papers)</p><p>In other words, data science in bioinformatics is where biology, statistics, and computer science converge.</p><p><strong>Why It Matters</strong><br />The real power of data science in bioinformatics is its ability to scale discovery.</p><p>Instead of studying one gene, we can study thousands.</p><p>Instead of analyzing one species, we can explore entire ecosystems.</p><p>Instead of waiting months for lab results, we can generate hypotheses in days.</p><p>From personalized medicine and cancer diagnostics to agricultural genomics and pandemic surveillance, data science is at the heart of the bioinformatics revolution.</p><p><strong>Final Thoughts</strong><br />If you&rsquo;re a biologist who&rsquo;s curious about code, or a data enthusiast fascinated by life sciences, bioinformatics is your playground&mdash;and data science is your toolkit.</p><p>In bioinformatics, data science isn&rsquo;t just useful. It&rsquo;s essential.</p><p>&nbsp;</p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/29917/gojs</guid>
	<pubDate>Tue, 22 Nov 2016 08:25:37 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/29917/gojs</link>
	<title><![CDATA[GoJS]]></title>
	<description><![CDATA[<p><strong>GoJS</strong> is a feature-rich JavaScript library for implementing custom interactive diagrams and complex visualizations across modern web browsers and platforms. <strong>GoJS</strong> makes constructing JavaScript diagrams of complex nodes, links, and groups easy with customizable templates and layouts.</p>
<p><strong>GoJS</strong> offers many advanced features for user interactivity such as drag-and-drop, copy-and-paste, in-place text editing, tooltips, context menus, automatic layouts, templates, data binding and models, transactional state and undo management, palettes, overviews, event handlers, commands, and an extensible tool system for custom operations.</p>
<p><strong>GoJS</strong> is pure JavaScript, so users get interactivity without requiring round-trips to servers and without plugins. <strong>GoJS</strong> normally runs completely in the browser, rendering to an HTML5 Canvas element or SVG without any server-side requirements. <strong>GoJS</strong> does not depend on any JavaScript libraries or frameworks, so it should work with any HTML or JavaScript framework or with no framework at all. &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;</p>
<p>More at&nbsp;http://gojs.net/latest/index.html</p><p>Address of the bookmark: <a href="http://gojs.net/latest/index.html" rel="nofollow">http://gojs.net/latest/index.html</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40703/%CF%80-cyc-a-reference-free-snp-discovery-application-using-parallel-graph-search</guid>
	<pubDate>Tue, 28 Jan 2020 03:34:23 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40703/%CF%80-cyc-a-reference-free-snp-discovery-application-using-parallel-graph-search</link>
	<title><![CDATA[Π-cyc: A Reference-free SNP Discovery Application using Parallel Graph Search]]></title>
	<description><![CDATA[<p>Reference free SNP search for comparative population genomics: multiple samples run simultanously. **experimental phase, compiles and runs with OpenMPI-1.8.8 with Intel Compiler only</p>
<p><span>Cycles enumeration (aka Bubbles) as part of de novo de bruijn graphs assembly using colours can be unpractical for large error prone genomes which makes the assembly process produce an excessive number of false positive cycles.&nbsp; Our solution is to search the graph in multicores shared memory parallel mode using graph decomposition then use filtering method to generate good quality SNPs.</span></p>
<p><a href="https://arxiv.org/abs/1809.06700">https://arxiv.org/abs/1809.06700</a></p>
<p><a href="https://github.com/redayounsi/2KP2P">https://github.com/redayounsi/2KP2P</a></p>
<blockquote>
<p>/2kp2omp/bin/main_2kp2_K63_C2 -i fastq_files.txt -o fungus_bub.fasta -r stat_fungus.txt -c cov_fungus_hash.txt -k 63 -h 20 -b 100 -g 600 -l 100 -f 16 -t 5.0 -x 1 -v 0 -p 1 -y 1 -u 1</p>
<p>&nbsp;</p>
</blockquote><p>Address of the bookmark: <a href="https://github.com/redayounsi/2KP2P" rel="nofollow">https://github.com/redayounsi/2KP2P</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42198/pggb-the-pangenome-graph-builder</guid>
	<pubDate>Sun, 13 Sep 2020 20:54:20 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42198/pggb-the-pangenome-graph-builder</link>
	<title><![CDATA[pggb: the pangenome graph builder]]></title>
	<description><![CDATA[<p><span>This pangenome graph construction pipeline renders a collection of sequences into a pangenome graph (in the variation graph model). Its goal is to build a graph that is locally directed and acyclic while preserving large-scale variation. Maintaining local linearity is important for the interpretation, visualization, and reuse of pangenome variation graphs.</span></p>
<p><img src="https://raw.githubusercontent.com/pangenome/pggb/master/data/images/DRB1-3123.fa.gz.pggb-s3000-p70-n10-a70-K11-k8-w10000-j5000-W0-e100.smooth.og.viz.png" alt="image" style="border: 0px;"></p><p>Address of the bookmark: <a href="https://github.com/pangenome/pggb" rel="nofollow">https://github.com/pangenome/pggb</a></p>]]></description>
	<dc:creator>biogeek</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44497/graphpath-a-graph-attention-model-for-molecular-stratification-with-interpretability-based-on-the-pathway-pathway-interaction-network</guid>
	<pubDate>Wed, 27 Mar 2024 20:51:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44497/graphpath-a-graph-attention-model-for-molecular-stratification-with-interpretability-based-on-the-pathway-pathway-interaction-network</link>
	<title><![CDATA[GraphPath: A graph attention model for molecular stratification with interpretability based on the pathway-pathway interaction network]]></title>
	<description><![CDATA[<p><span>Achieving accurate and interpretable clinical predictions requires paramount attention to thoroughly characterizing patients at both the molecular and biological pathway levels. In this paper, we present GraphPath, a biological knowledge-driven graph neural network with multi-head self-attention mechanism that implements the pathway-pathway interaction network. We train GraphPath to classify the cancer status of patients with prostate cancer based on their multi-omics profiling.</span></p>
<p><span><img src="https://github.com/amazingma/GraphPath/raw/main/Figures/GraphPath.png" alt="image" style="border: 0px;"></span></p><p>Address of the bookmark: <a href="https://github.com/amazingma/GraphPath" rel="nofollow">https://github.com/amazingma/GraphPath</a></p>]]></description>
	<dc:creator>LEGE</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34525/hic-pro-an-optimized-and-flexible-pipeline-for-hi-c-data-processing</guid>
	<pubDate>Wed, 06 Dec 2017 01:05:21 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34525/hic-pro-an-optimized-and-flexible-pipeline-for-hi-c-data-processing</link>
	<title><![CDATA[HiC-Pro: an optimized and flexible pipeline for Hi-C data processing]]></title>
	<description><![CDATA[<p><span>HiC-Pro was designed to process Hi-C data, from raw fastq files (paired-end Illumina data) to the normalized contact maps. Since version 2.7.0, HiC-Pro supports the main Hi-C protocols, including digestion protocols as well as protocols that do not require restriction enzyme such as DNase Hi-C. In practice, HiC-Pro can be used to process dilution Hi-C, in situ Hi-C, DNase Hi-C, Micro-C, capture-C, capture Hi-C or HiChip data.</span></p>
<p>&nbsp;</p>
<p>http://nservant.github.io/HiC-Pro/</p><p>Address of the bookmark: <a href="http://nservant.github.io/HiC-Pro/" rel="nofollow">http://nservant.github.io/HiC-Pro/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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