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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/43374?offset=480</link>
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	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42923/flanker</guid>
	<pubDate>Sat, 27 Feb 2021 22:04:53 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42923/flanker</link>
	<title><![CDATA[Flanker]]></title>
	<description><![CDATA[<p><span>Flanker, a Python package which performs alignment-free clustering of gene flanking sequences in a consistent format, allowing investigation of&nbsp;<span>mobile genetic elements (</span>MGEs) without prior knowledge of their structure.&nbsp;<span>Flanker can be flexibly parameterised to finetune outputs by characterising upstream and downstream regions separately and investigating variable lengths of flanking sequence.</span></span></p>
<p><span><img src="https://github.com/wtmatlock/flanker/raw/main/docs/frontpage.png" alt="image" style="border: 0px;"></span></p><p>Address of the bookmark: <a href="https://github.com/wtmatlock/flanker" rel="nofollow">https://github.com/wtmatlock/flanker</a></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43088/iva-accurate-de-novo-assembly-of-rna-virus-genomes</guid>
	<pubDate>Wed, 23 Jun 2021 07:51:59 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43088/iva-accurate-de-novo-assembly-of-rna-virus-genomes</link>
	<title><![CDATA[IVA: accurate de novo assembly of RNA virus genomes]]></title>
	<description><![CDATA[<p>IVA (Iterative Virus Assembler) designed specifically for read pairs sequenced at highly variable depth from RNA virus samples. We tested IVA on datasets from 140 sequenced samples from human immunodeficiency virus-1 or influenza-virus-infected people and demonstrated that IVA outperforms all other virus de novo assemblers.</p>
<p><strong> Availability and implementation: </strong> The software runs under Linux, has the GPLv3 licence and is freely available from http://sanger-pathogens.github.io/iva</p>
<p>https://pubmed.ncbi.nlm.nih.gov/25725497/</p><p>Address of the bookmark: <a href="https://github.com/sanger-pathogens/iva" rel="nofollow">https://github.com/sanger-pathogens/iva</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43364/ragtag-a-collection-of-software-tools-for-scaffolding-and-improving-modern-genome-assemblies</guid>
	<pubDate>Sat, 11 Sep 2021 00:28:14 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43364/ragtag-a-collection-of-software-tools-for-scaffolding-and-improving-modern-genome-assemblies</link>
	<title><![CDATA[RagTag: a collection of software tools for scaffolding and improving modern genome assemblies]]></title>
	<description><![CDATA[<p>RagTag is a collection of software tools for scaffolding and improving modern genome assemblies. Tasks include:</p>
<ul>
<li>Homology-based misassembly&nbsp;<a href="https://github.com/malonge/RagTag/wiki/correct">correction</a></li>
<li>Homology-based assembly&nbsp;<a href="https://github.com/malonge/RagTag/wiki/scaffold">scaffolding</a>&nbsp;and&nbsp;<a href="https://github.com/malonge/RagTag/wiki/patch">patching</a></li>
<li>Scaffold&nbsp;<a href="https://github.com/malonge/RagTag/wiki/merge">merging</a></li>
</ul><p>Address of the bookmark: <a href="https://github.com/malonge/RagTag" rel="nofollow">https://github.com/malonge/RagTag</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43661/maftools</guid>
	<pubDate>Fri, 17 Dec 2021 03:18:28 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43661/maftools</link>
	<title><![CDATA[maftools]]></title>
	<description><![CDATA[<p>With advances in Cancer Genomics, <a href="https://docs.gdc.cancer.gov/Data/File_Formats/MAF_Format/">Mutation Annotation Format</a> (MAF) is being widely accepted and used to store somatic variants detected. <a href="http://cancergenome.nih.gov">The Cancer Genome Atlas</a> Project has sequenced over 30 different cancers with sample size of each cancer type being over 200. <a href="https://wiki.nci.nih.gov/display/TCGA/TCGA+MAF+Files">Resulting data</a> consisting of somatic variants are stored in the form of <a href="https://docs.gdc.cancer.gov/Data/File_Formats/MAF_Format/">Mutation Annotation Format</a>. This package attempts to summarize, analyze, annotate and visualize MAF files in an efficient manner from either TCGA sources or any in-house studies as long as the data is in MAF format.</p>
<p>https://www.bioconductor.org/packages/devel/bioc/vignettes/maftools/inst/doc/maftools.html</p><p>Address of the bookmark: <a href="https://github.com/PoisonAlien/maftools" rel="nofollow">https://github.com/PoisonAlien/maftools</a></p>]]></description>
	<dc:creator>Surabhi Chaudhary</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/43817/bioinfo-lab</guid>
  <pubDate>Fri, 04 Mar 2022 00:17:00 -0600</pubDate>
  <link></link>
  <title><![CDATA[Bioinfo Lab]]></title>
  <description><![CDATA[
<p>The Institute of Bioinformatics conducts internationally renowned research and provides profound education in bioinformatics. Its research focuses on development and application of machine learning and statistical methods in biology and medicine.</p>

<p>Contact:<br />Computer Science Building (Science Park 3)<br />Altenberger Str. 69, A-4040 Linz, Austria<br />Tel. +43 732 2468 4520 / Fax +43 732 2468 4539<br />E-mail secretary@bioinf.jku.at</p>

<p>http://www.bioinf.jku.at/</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44307/genomenotebook</guid>
	<pubDate>Thu, 20 Apr 2023 13:19:01 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44307/genomenotebook</link>
	<title><![CDATA[genomenotebook]]></title>
	<description><![CDATA[<p><a href="https://dbikard.github.io/genomenotebook/">https://dbikard.github.io/genomenotebook/</a></p>
<h2>Install<a href="https://dbikard.github.io/genomenotebook/#install"></a></h2>
<pre><code>pip install genomenotebook</code></pre>
<h2>How to use<a href="https://dbikard.github.io/genomenotebook/#how-to-use"></a></h2>
<p>Create a simple genome browser with a search bar. The sequence appears when zooming in.</p>
<div>
<div id="cb2">
<pre><code><span><a href="https://dbikard.github.io/genomenotebook/#cb2-1"></a><span>import</span> genomenotebook <span>as</span> gn</span>
<span><a href="https://dbikard.github.io/genomenotebook/#cb2-2"></a></span>
<span><a href="https://dbikard.github.io/genomenotebook/#cb2-3"></a>g<span>=</span>gn.GenomeBrowser(genome_path, gff_path, init_pos<span>=</span><span>10000</span>)</span>
<span><a href="https://dbikard.github.io/genomenotebook/#cb2-4"></a>g.show()</span></code><button title="Copy to Clipboard"></button></pre>
</div>
</div>
<p>Tracks can be added to visualize your favorite genomics data. See&nbsp;<code>Examples</code>&nbsp;for more !!!!</p><p>Address of the bookmark: <a href="https://dbikard.github.io/genomenotebook/" rel="nofollow">https://dbikard.github.io/genomenotebook/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/44377/mitochondrial-genome-assembly-tools</guid>
	<pubDate>Wed, 06 Sep 2023 00:37:18 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/44377/mitochondrial-genome-assembly-tools</link>
	<title><![CDATA[Mitochondrial genome assembly tools !]]></title>
	<description><![CDATA[<p>Mitochondrial genome assembly tools are specialized software and algorithms designed to accurately reconstruct the mitochondrial genome (mitogenome) from sequencing data, typically obtained through techniques like next-generation sequencing (NGS). The mitochondrial genome is relatively small compared to the nuclear genome, making it an ideal target for assembly. Here are some commonly used mitochondrial genome assembly tools:</p><p><strong>MitoFinder:</strong> Mitofinder is a pipeline to assemble mitochondrial genomes and annotate mitochondrial genes from trimmed read sequencing data.</p><p><strong>MitoHiFi:</strong> a python pipeline for mitochondrial genome assembly from PacBio high fidelity reads</p><p>MITObim: MITObim is a tool specifically developed for the iterative assembly of mitochondrial genomes. It starts with a reference mitogenome and iteratively refines the assembly using the read data.</p><p><strong>MITOS:</strong> MITOS is a web-based platform that provides a pipeline for annotating mitochondrial genomes. It integrates multiple software tools for assembly, annotation, and visualization of mitogenomes.</p><p><strong>MIRA:</strong> MIRA (Mimicking Intelligent Read Assembly) is a versatile genome assembly tool that can be used for mitochondrial genome assembly. It supports various sequencing technologies and allows for reference-based or de novo assembly.</p><p><strong>NOVOPlasty:</strong> NOVOPlasty is a user-friendly tool designed for de novo assembly of organelle genomes, including mitochondria. It utilizes a seed-and-extend algorithm and is suitable for both short-read and long-read data.</p><p><strong>MITOS2:</strong> MITOS2 is an updated version of the MITOS pipeline, which automates the annotation of mitochondrial genomes. It provides improved accuracy and additional features for mitochondrial genome analysis.</p><p><strong>GetOrganelle:</strong> While primarily designed for chloroplast genome assembly, GetOrganelle can also be used for mitochondrial genome assembly. It is particularly useful for dealing with high-throughput sequencing data.</p><p><strong>SPAdes:</strong> SPAdes (St. Petersburg genome assembler) is a versatile genome assembly tool that can be employed for mitochondrial genome assembly, especially when dealing with complex datasets that may contain nuclear mitochondrial DNA sequences (numts).</p><p><strong>IDBA-UD:</strong> IDBA-UD (Iterative De Bruijn Graph De Novo Assembler) is another de novo assembly tool that can be used for mitochondrial genome assembly, especially in cases with relatively low coverage.</p><p><strong>Velvet:</strong> Velvet is a de novo assembly tool that can be applied to mitochondrial genome assembly, especially when working with short-read data.</p><p>When selecting a mitochondrial genome assembly tool, it's important to consider the specific characteristics of your sequencing data, such as read length and coverage, as well as the complexity of the mitochondrial genome. Additionally, some tools are better suited for specific organisms or research objectives, so choosing the right tool will depend on your particular project requirements.</p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/view/982</guid>
	<pubDate>Wed, 17 Jul 2013 15:25:09 -0500</pubDate>
	<link>https://bioinformaticsonline.com/view/982</link>
	<title><![CDATA[Is reference genome necessary for gene expression study in transcriptome sequencing or for variant discovery in genome sequencing?]]></title>
	<description><![CDATA[<p><span>Like in case of plant genomes where nature of genome is too complex and huge in size to accomplish complete<em> de novo</em> assembly by current sequencing technology. What would be alternate solution? Can we live in reference free world?</span></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/4183/320000-viruses-in-mammals-yet-to-sequenced-in-future</guid>
	<pubDate>Tue, 03 Sep 2013 08:35:30 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/4183/320000-viruses-in-mammals-yet-to-sequenced-in-future</link>
	<title><![CDATA[320000 viruses in mammals yet to sequenced in future!!!]]></title>
	<description><![CDATA[<p>With current biological technique improvements, finally it is now possible to look at millions of unknown viruses at genomic level and understand the mechanism. According to available data, close to 70 per cent of emerging viral diseases such as HIV/AIDS, West Nile, Ebola, SARS, and influenza, are zoonoses - infections of animals that cross into humans.</p><p>To address the challenges of describing and estimating virodiversity, a team of investigators from Center for Infection and Immunity (CII) and EcoHealth Alliance began in jungles of Bangladesh - home to the flying fox.</p><p>Reference:</p><p><a href="http://economictimes.indiatimes.com/news/news-by-industry/et-cetera/mammals-harbour-at-least-320000-new-viruses/articleshow/22253268.cms">http://economictimes.indiatimes.com/news/news-by-industry/et-cetera/mammals-harbour-at-least-320000-new-viruses/articleshow/22253268.cms</a></p><p><a href="http://www.bbc.co.uk/news/science-environment-23932400">http://www.bbc.co.uk/news/science-environment-23932400</a></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4960/genome-epigenome-new-understanding-of-the-pathogens-in-your-food</guid>
	<pubDate>Fri, 27 Sep 2013 11:30:45 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4960/genome-epigenome-new-understanding-of-the-pathogens-in-your-food</link>
	<title><![CDATA[Genome + Epigenome = New Understanding of the Pathogens in Your Food]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/hGtHs_C1BFA" frameborder="0" allowfullscreen></iframe>UC Davis's Bart Weimer describes foodborne pathogens and their proclivity for rapid genome rearrangement. The 100K Pathogen Genome Project he leads is using PacBio long-read sequencing to close genomes and analyze methylation; Weimer reports that his team has already discovered new epigenetic modifications in Salmonella and Listeria with the technology. www.pacb.com/microbe]]></description>
	
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