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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/43896?offset=30</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/file/view/37581/comparativegenomics-exercise2</guid>
	<pubDate>Wed, 22 Aug 2018 22:10:56 -0500</pubDate>
	<link>https://bioinformaticsonline.com/file/view/37581/comparativegenomics-exercise2</link>
	<title><![CDATA[ComparativeGenomics Exercise2]]></title>
	<description><![CDATA[<p>COMPARATIVE MICROBIAL GENOMICS ANALYSIS WORKSHOP&nbsp; @&nbsp;cbs.dtu.dk</p><p>Free Bioinformatics workbench https://www.mn.uio.no/ifi/english/research/networks/clsi/earlier_seminars/2012/tammivesth_osloseminarfinal.pdf</p>]]></description>
	<dc:creator>Neel</dc:creator>
	<enclosure url="https://bioinformaticsonline.com/file/download/37581" length="139956" type="application/pdf" />
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/42903/katherine-belov-lab</guid>
  <pubDate>Sun, 21 Feb 2021 22:59:35 -0600</pubDate>
  <link></link>
  <title><![CDATA[Katherine Belov Lab]]></title>
  <description><![CDATA[
<p>Evolution of the adaptive immune system Marsupial and monotreme immune genes MHC Diversity and Conservation Marsupial and monotreme genomics Comparative Genomics Genetics of Tasmanian Devil facial tumour disease</p>

<p>More at https://www.sydney.edu.au/science/about/our-people/academic-staff/kathy-belov.html</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/34485/phyloxml-xml-for-evolutionary-biology-and-comparative-genomics</guid>
	<pubDate>Wed, 29 Nov 2017 10:04:48 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/34485/phyloxml-xml-for-evolutionary-biology-and-comparative-genomics</link>
	<title><![CDATA[phyloXML:  XML for evolutionary biology and comparative genomics]]></title>
	<description><![CDATA[<p><a href="http://www.biomedcentral.com/1471-2105/10/356/">phyloXML</a><span>&nbsp;(</span><a href="http://www.phyloxml.org/examples_syntax/phyloxml_syntax_example_1.html">example</a><span>) is an&nbsp;</span><a href="http://en.wikipedia.org/wiki/XML">XML</a><span>&nbsp;language designed to describe phylogenetic trees (or networks) and associated data. PhyloXML provides elements for commonly used features, such as taxonomic information, gene names and identifiers, branch lengths, support values, and gene duplication and speciation events. Using these standardized elements allows interoperability between various applications and databases. Furthermore, both due to extensible nature of XML itself and the provision of &lt;property&gt; elements by phyloXML, extensibility as well as domain specific applications are ensured. The structure of phyloXML is described by&nbsp;</span><a href="http://en.wikipedia.org/wiki/XML_Schema_%28W3C%29">XML Schema Definition (XSD)</a><span>&nbsp;language.</span></p><p>Address of the bookmark: <a href="http://www.phyloxml.org/" rel="nofollow">http://www.phyloxml.org/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40369/phyloxml-xml-for-evolutionary-biology-and-comparative-genomics</guid>
	<pubDate>Sun, 08 Dec 2019 09:41:18 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40369/phyloxml-xml-for-evolutionary-biology-and-comparative-genomics</link>
	<title><![CDATA[phyloXML: XML for evolutionary biology and comparative genomics]]></title>
	<description><![CDATA[<p><a href="http://www.biomedcentral.com/1471-2105/10/356/">phyloXML</a><span>&nbsp;(</span><a href="http://www.phyloxml.org/examples_syntax/phyloxml_syntax_example_1.html">example</a><span>) is an&nbsp;</span><a href="http://en.wikipedia.org/wiki/XML">XML</a><span>&nbsp;language designed to describe phylogenetic trees (or networks) and associated data. PhyloXML provides elements for commonly used features, such as taxonomic information, gene names and identifiers, branch lengths, support values, and gene duplication and speciation events. Using these standardized elements allows interoperability between various applications and databases. Furthermore, both due to extensible nature of XML itself and the provision of &lt;property&gt; elements by phyloXML, extensibility as well as domain specific applications are ensured. The structure of phyloXML is described by&nbsp;</span><a href="http://en.wikipedia.org/wiki/XML_Schema_%28W3C%29">XML Schema Definition (XSD)</a><span>&nbsp;language.</span></p>
<p><a href="http://www.phyloxml.org/archaeopteryx-js/adh.html">http://www.phyloxml.org/archaeopteryx-js/adh.html</a></p><p>Address of the bookmark: <a href="http://www.phyloxml.org/" rel="nofollow">http://www.phyloxml.org/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/42143/sibelia-a-comparative-genomics-tool</guid>
	<pubDate>Sat, 22 Aug 2020 02:49:00 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/42143/sibelia-a-comparative-genomics-tool</link>
	<title><![CDATA[Sibelia: A comparative genomics tool]]></title>
	<description><![CDATA[<p><strong>Sibelia</strong>: A comparative genomics tool: It assists biologists in analysing the genomic variations that correlate with pathogens, or the genomic changes that help microorganisms adapt in different environments. Sibelia will also be helpful for the evolutionary and genome rearrangement studies for multiple strains of microorganisms.&nbsp;</p>
<p><strong>Sibelia</strong>&nbsp;is useful in finding: (1) shared regions, (2) regions that present in one group of genomes but not in others, (3) rearrangements that transform one genome to other genomes.</p>
<p>More at&nbsp;<a href="http://bioinf.spbau.ru/sibelia">http://bioinf.spbau.ru/sibelia</a></p>
<p>Sibelia docs&nbsp;<a href="http://gensoft.pasteur.fr/docs/Sibelia/3.0.7/SIBELIA.md">http://gensoft.pasteur.fr/docs/Sibelia/3.0.7/SIBELIA.md</a></p><p>Address of the bookmark: <a href="https://github.com/bioinf/Sibelia" rel="nofollow">https://github.com/bioinf/Sibelia</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43683/genview-a-phylogeny-based-comparative-genomics-software-to-analyze-the-genetic-environment-of-genes</guid>
	<pubDate>Tue, 28 Dec 2021 01:49:03 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43683/genview-a-phylogeny-based-comparative-genomics-software-to-analyze-the-genetic-environment-of-genes</link>
	<title><![CDATA[GEnView: A phylogeny based comparative genomics software to analyze the genetic environment of genes]]></title>
	<description><![CDATA[<p><span>A phylogeny based comparative genomics software to analyze the genetic environment of genes. The user can select one or several taxa and provide one or several reference protein(s). Genomes and plasmids (based on user choice) will be downloaded from the NCBI Assembly/NR database and searched for the respective gene. Alternatively, custom genomes can be provided. User selected stretches (20kbp by default) of the genes genetic environment are extracted, annotated and aligned between all genomes. The sequences are then visualized, enabling comparison of synteny and gene content.</span></p>
<p><span>More at&nbsp;https://pubmed.ncbi.nlm.nih.gov/34951622/</span></p><p>Address of the bookmark: <a href="https://github.com/EbmeyerSt/GEnView" rel="nofollow">https://github.com/EbmeyerSt/GEnView</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/20454/comparative-genomics-in-ensembl</guid>
	<pubDate>Wed, 21 Jan 2015 08:31:11 -0600</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/20454/comparative-genomics-in-ensembl</link>
	<title><![CDATA[Comparative Genomics in Ensembl]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/dDRdCnZOMCM" frameborder="0" allowfullscreen></iframe>The Ensembl browser provides viewable whole-genome alignments, homologues and phylogenetic gene trees, protein families, and ancestral sequences.  Learn how to view and export these data in this video.]]></description>
	
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26525/ensembl-comparative-genomics-resources</guid>
	<pubDate>Sun, 28 Feb 2016 17:10:20 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26525/ensembl-comparative-genomics-resources</link>
	<title><![CDATA[Ensembl comparative genomics resources]]></title>
	<description><![CDATA[<div>
<p>The Ensembl comparative genomics resources are one such reference set that facilitates comprehensive and reproducible analysis of chordate genome data. Ensembl computes pairwise and multiple whole-genome alignments from which large-scale synteny, per-base conservation scores and constrained elements are obtained. Gene alignments are used to define Ensembl Protein Families, GeneTrees and homologies for both protein-coding and non-coding RNA genes. These resources are updated frequently and have a consistent informatics infrastructure and data presentation across all supported species. Specialized web-based visualizations are also available including synteny displays, collapsible gene tree plots, a gene family locator and different alignment views. The Ensembl comparative genomics infrastructure is extensively reused for the analysis of non-vertebrate species by other projects including Ensembl Genomes and Gramene and much of the information here is relevant to these projects. The consistency of the annotation across species and the focus on vertebrates makes Ensembl an ideal system to perform and support vertebrate comparative genomic analyses. We use robust software and pipelines to produce reference comparative data and make it freely available.</p>
<p><strong>Database URL:</strong> <a href="http://www.ensembl.org" target="pmc_ext">http://www.ensembl.org</a>.</p>
</div><p>Address of the bookmark: <a href="http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761110/" rel="nofollow">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761110/</a></p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44002/interesting-bioinformatics-resources</guid>
	<pubDate>Fri, 11 Nov 2022 06:30:46 -0600</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44002/interesting-bioinformatics-resources</link>
	<title><![CDATA[Interesting Bioinformatics Resources !]]></title>
	<description><![CDATA[<p>1. a reproducible workflow.&nbsp;<a href="https://www.youtube.com/watch?v=s3JldKoA0zw">https://www.youtube.com/watch?v=s3JldKoA0zw</a>&nbsp;This two minute video will change your mind on reproducible research&nbsp;</p><p>2. Parallel sequencing lives, or what makes large sequencing projects successful&nbsp;<a href="https://academic.oup.com/gigascience/article/6/11/gix100/4557140?login=false">https://academic.oup.com/gigascience/article/6/11/gix100/4557140?login=false</a></p><p>3. Common-sense approaches to sharing tabular data alongside publication&nbsp;<a href="https://www.sciencedirect.com/science/article/pii/S2666389921002300">https://www.sciencedirect.com/science/article/pii/S2666389921002300</a></p><p>4. A Reproducible Data Analysis Workflow with R Markdown, Git, Make, and Docker&nbsp;<a href="https://psyarxiv.com/8xzqy/">https://psyarxiv.com/8xzqy/</a></p><p>5. Practical Computational Reproducibility in the Life Sciences&nbsp;<a href="https://www.cell.com/cell-systems/fulltext/S2405-4712(18)30140-6">https://www.cell.com/cell-systems/fulltext/S2405-4712(18)30140-6</a></p><p>6. A video by Dr.Keith A. Baggerly from MD Anderson [The Importance of Reproducible Research in High-Throughput Biology](<a href="https://www.youtube.com/watch?v=7gYIs7uYbMo">https://www.youtube.com/watch?v=7gYIs7uYbMo</a>) highly recommended.</p><p>7. Ten Simple Rules for Reproducible Computational Research&nbsp;<a href="http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003285">http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1003285</a>)</p><p>8. Good Enough Practices in Scientific Computing&nbsp;<a href="http://arxiv.org/abs/1609.00037">http://arxiv.org/abs/1609.00037</a>&nbsp;</p><p>9. Best Practices for Scientific Computing&nbsp;<a href="https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001745">https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.1001745</a></p><p>10. A Quick Guide to Organizing Computational Biology Projects&nbsp;<a href="http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.100042">http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.100042</a>&nbsp; A must read for computational biologists!</p><p>11. Reproducibility of computational workflows is automated using continuous analysis&nbsp;<a href="https://www.nature.com/articles/nbt.3780">https://www.nature.com/articles/nbt.3780</a></p><p>12. Five selfish reasons to work reproducibly&nbsp;<a href="https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0850-7">https://genomebiology.biomedcentral.com/articles/10.1186/s13059-015-0850-7</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/36384/binding-site-prediction-in-protein</guid>
	<pubDate>Wed, 25 Apr 2018 04:35:57 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/36384/binding-site-prediction-in-protein</link>
	<title><![CDATA[Binding Site Prediction in Protein !]]></title>
	<description><![CDATA[<p><span>The interaction between proteins and other molecules is fundamental to all biological functions. In this section we include tools that can assist in prediction of interaction sites on protein surface and tools for predicting the structure of the intermolecular complex formed between two or more molecules (docking).</span></p><h4>Pockets Identification</h4><p><a href="http://sts.bioengr.uic.edu/castp/" target="_blank">CASTp</a></p><div style="text-align: justify;">Automatic Identification of pockets and cavities in proteins structure, and quantitation of their volumes using Delaunay triangulation. Available also as PyMOL plugin</div><p><a href="http://www.bioinformatics.leeds.ac.uk/pocketfinder/" target="_blank">Pocket-Finder</a></p><div style="text-align: justify;">Automatic identification of pockets and cavities in proteins structure, and quantitation of their volumes.</div><p><a href="http://gecco.org.chemie.uni-frankfurt.de/pocketpicker/index.html" target="_blank">PocketPicker</a></p><div style="text-align: justify;">Grid-based technique for the analysis of protein pockets. PocketPicker available as a plugin for&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/pymol.htm">PyMOL</a></div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;"><h4>Binding Site Prediction</h4>
<p><a href="http://consurf.tau.ac.il/" target="_blank">ConSurf</a></p>
</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">Identification of functional regions in proteins by surface-mapping of phylogenetic information</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;"><a href="http://www-cryst.bioc.cam.ac.uk/~crescendo/crescendo.php" target="_blank">CRESCENDO</a></div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">Identification protein interaction sites. It uses sequence conservation patterns in homologous proteins to distinguish between residues that are conserved due to structural restraints from those due to functional restraints.&nbsp;&nbsp;</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;"><strong>Ligand Binding Sites</strong></div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;"><a href="http://www.sbg.bio.ic.ac.uk/~3dligandsite/" target="_blank">3DLigandSite</a></div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">The server utilizes protein-structure prediction to provide structural models of the binding site. Ligands bound to structures are superimposed onto the model and use to predict the binding site.</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">F<a href="http://cssb.biology.gatech.edu/skolnick/files/FINDSITE/" target="_blank">INDSITE</a></div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">A threading-based method for ligand-binding site prediction and functional annotation based on binding-site similarity across superimposed groups of threading templates.</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">
<p><a href="http://scoppi.biotec.tu-dresden.de/pocket/" target="_blank">LIGSITE<sup>csc</sup></a></p>
<div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">Prediction of binding site by pocket identification using the Connolly surface and degree of conservation</div>
<p><a href="http://metapocket.eml.org/" target="_blank"></a></p>
</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;"><a href="http://metapocket.eml.org/" target="_blank">metaPocket</a>A meta server for ligand-binding site prediction. metaPocket use&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/binding.htm#ligsite">LIGSITE<sup>csc</sup></a>,&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/binding.htm#pass">PASS</a>,&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/binding.htm#qsite">Q-SiteFinder</a>&nbsp;and&nbsp;<a href="http://www.biochem.ucl.ac.uk/~roman/surfnet/surfnet.html" target="_blank">SURFNET</a></div>]]></description>
	<dc:creator>Poonam Mahapatra</dc:creator>
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