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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/44213?</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/36384/binding-site-prediction-in-protein</guid>
	<pubDate>Wed, 25 Apr 2018 04:35:57 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/36384/binding-site-prediction-in-protein</link>
	<title><![CDATA[Binding Site Prediction in Protein !]]></title>
	<description><![CDATA[<p><span>The interaction between proteins and other molecules is fundamental to all biological functions. In this section we include tools that can assist in prediction of interaction sites on protein surface and tools for predicting the structure of the intermolecular complex formed between two or more molecules (docking).</span></p><h4>Pockets Identification</h4><p><a href="http://sts.bioengr.uic.edu/castp/" target="_blank">CASTp</a></p><div style="text-align: justify;">Automatic Identification of pockets and cavities in proteins structure, and quantitation of their volumes using Delaunay triangulation. Available also as PyMOL plugin</div><p><a href="http://www.bioinformatics.leeds.ac.uk/pocketfinder/" target="_blank">Pocket-Finder</a></p><div style="text-align: justify;">Automatic identification of pockets and cavities in proteins structure, and quantitation of their volumes.</div><p><a href="http://gecco.org.chemie.uni-frankfurt.de/pocketpicker/index.html" target="_blank">PocketPicker</a></p><div style="text-align: justify;">Grid-based technique for the analysis of protein pockets. PocketPicker available as a plugin for&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/pymol.htm">PyMOL</a></div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;"><h4>Binding Site Prediction</h4>
<p><a href="http://consurf.tau.ac.il/" target="_blank">ConSurf</a></p>
</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">Identification of functional regions in proteins by surface-mapping of phylogenetic information</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;"><a href="http://www-cryst.bioc.cam.ac.uk/~crescendo/crescendo.php" target="_blank">CRESCENDO</a></div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">Identification protein interaction sites. It uses sequence conservation patterns in homologous proteins to distinguish between residues that are conserved due to structural restraints from those due to functional restraints.&nbsp;&nbsp;</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;"><strong>Ligand Binding Sites</strong></div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;"><a href="http://www.sbg.bio.ic.ac.uk/~3dligandsite/" target="_blank">3DLigandSite</a></div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">The server utilizes protein-structure prediction to provide structural models of the binding site. Ligands bound to structures are superimposed onto the model and use to predict the binding site.</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">F<a href="http://cssb.biology.gatech.edu/skolnick/files/FINDSITE/" target="_blank">INDSITE</a></div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">A threading-based method for ligand-binding site prediction and functional annotation based on binding-site similarity across superimposed groups of threading templates.</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">
<p><a href="http://scoppi.biotec.tu-dresden.de/pocket/" target="_blank">LIGSITE<sup>csc</sup></a></p>
<div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;">Prediction of binding site by pocket identification using the Connolly surface and degree of conservation</div>
<p><a href="http://metapocket.eml.org/" target="_blank"></a></p>
</div><div style="text-align: justify;">&nbsp;</div><div style="text-align: justify;"><a href="http://metapocket.eml.org/" target="_blank">metaPocket</a>A meta server for ligand-binding site prediction. metaPocket use&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/binding.htm#ligsite">LIGSITE<sup>csc</sup></a>,&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/binding.htm#pass">PASS</a>,&nbsp;<a href="https://bip.weizmann.ac.il/toolbox/structure/binding.htm#qsite">Q-SiteFinder</a>&nbsp;and&nbsp;<a href="http://www.biochem.ucl.ac.uk/~roman/surfnet/surfnet.html" target="_blank">SURFNET</a></div>]]></description>
	<dc:creator>Poonam Mahapatra</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/43896/list-of-comparative-genomics-resources</guid>
	<pubDate>Tue, 28 Jun 2022 04:08:06 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/43896/list-of-comparative-genomics-resources</link>
	<title><![CDATA[List of comparative genomics resources !]]></title>
	<description><![CDATA[<div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1096638041"><span>3D-GENOMICS -- A Database to Compare Structural and Functional Annotations of Proteins between Sequenced Genomes</span></a></div><p>Compare structural and functional annotations of proteins between sequenced genomes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1100640374"><span>ARED Organism -- expansion of ARED reveals AU-rich element cluster variations between human and mouse</span></a></div><p>View AREs in the human transcriptome and study the comparative genomics of AREs in model organisms.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1234973128"><span>ATGC -- Alignable Tight Genomic Clusters Database</span></a></div><p>Find information about orthologous genes in prokaryotes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1174596104"><span>AnimalQTLdb -- a livestock QTL database tool set for positional QTL information mining and beyond</span></a></div><p>Search for publicly available QTL data on livestocks and animal species.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL20110518150135"><span>BGDB -- Bovine Genome Database</span></a></div><p>Find information about bovine genomics data.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1229012662"><span>COMPARE -- a multi-organism system for cross-species data comparison and transfer of information</span></a></div><p>A multi-organism web-based resource system designed to easily retrieve, correlate and interpret data across species.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1218141952"><span>CONDOR -- COnserved Non-coDing Orthologous Regions</span></a></div><p>A database resource of developmentally associated conserved non-coding elements.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1099057221"><span>CORG -- A database for COmparative Regulatory Genomics</span></a></div><p>Delineate conserved non-coding blocks from upstream regions of putative orthologous gene pairs from man, mouse, rat, fugu, Mus musculus, Danio rerio, and zebrafish.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1203608896"><span>COXPRESdb -- a database of coexpressed gene networks in mammals</span></a></div><p>Find coexpressed gene lists and networks in human and mouse.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1097763045"><span>CVTree -- A Phylogenetic Tree Reconstruction Tool Based on Whole Genomes</span></a></div><p>Construct phylogenetic tree of microorganisms based on oligopeptide content of their complete proteomes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1232729680"><span>CleanEST -- the cleansed EST libraries database</span></a></div><p>A novel database server that classifies GenBank's dbEST (database of expressed gene sequences) libraries and removes contaminants.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1256926144"><span>CoCoa -- COefficient of COAncestry software</span></a></div><p>Find information about the ancestral relationship between genes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1227549154"><span>CoGemiR -- a comparative genomics microRNA database</span></a></div><p>Provides an overview of the genomic organization of microRNAs and extent of conservation during evolution in different metazoan species.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1117678221"><span>Comparative Genometrics (CG) -- a database dedicated to biometric comparisons of whole genomes</span></a></div><p>Conduct comparative biometric analysis of chromosomes of different organisms.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1151007916"><span>DoTS -- Database Of Transcribed Sequences</span></a></div><p>Search for Indices of gene and transcripts in human and mouse.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1174510065"><span>DroSpeGe -- rapid access database for new Drosophila species genomes</span></a></div><p>Search and compare 12 new and old Drosophila genomes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1098208414"><span>ECR Browser -- A Tool for Visualizing and Accessing Data from Comparisons of Multiple Vertebrate Genomes</span></a></div><p>Access to whole genome alignments of human, mouse, rat and fish sequences.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1209738459"><span>EPGD -- Eukaryotic Paralog Group Database</span></a></div><p>Find eukaryotic paralog/paralogon information.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1232726869"><span>EVOG -- evolutionary visualizer for overlapping genes</span></a></div><p>Analyze the evolutionary process of overlapping genes when comparing different species.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1227633714"><span>GNAT -- Inter-species gene mention normalization (ISGN)</span></a></div><p>The first publicly available system reported to handle inter-species gene mention normalization.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1229438992"><span>GenColors -- annotation and comparative genomics of prokaryotes made easy</span></a></div><p>A web-based software/database system aimed at an improved and accelerated annotation of prokaryotic genomes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1151086258"><span>GeneNest gene indices</span></a></div><p>Visualize gene indices of human, mouse, Arabidopsis, Zebrafish, Drosophila and Sheep.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1174489378"><span>GenomeTrafac -- a whole genome resource for the detection of transcription factor binding site clusters associated with conventional and microRNA encoding genes conserved between mouse and human gene orthologs</span></a></div><p>Use comparative genomics approach to characterize gene models and identify putative cis-regulatory regions of RefSeq Gene Orthologs.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL20110518150753"><span>IKMC -- International Knockout Mouse Consortium web portal</span></a></div><p>Find information about mutated mouse genes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1209411604"><span>IMG/M -- Integrated Microbial Genomes/Metagenomes</span></a></div><p>A data management and analysis system for metagenomes</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1234976694"><span>ISED -- Influenza sequence and epitope database.</span></a></div><p>Search for influenza sequence, vaccine, and drug resistance information.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL20140710115515"><span>LAMDHI: The Search for Animal Models Starts Here</span></a></div><p>LAMHDI, the initiative to Link Animal Models to Human DIsease, is designed to accelerate the research process by providing biomedical researchers with a simple, comprehensive Web-based resource to find the best animal models for their research.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1228843803"><span>MANTIS -- a phylogenetic framework for multi-species genome comparisons</span></a></div><p>The missing link between multi-species full genome comparisons and functional analysis.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1099578148"><span>MBGD -- Microbial genome database for comparative analysis</span></a></div><p>Conduct comparative analysis of completely sequenced microbial genomes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1221077729"><span>MEGA -- Molecular Evolutionary Genetics Analysis</span></a></div><p>A biologist-centric software for evolutionary analysis of DNA and protein sequences.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1174596756"><span>MamPol -- a database of nucleotide polymorphism in the Mammalia class</span></a></div><p>Conduct single nucleotide polymorphisms diversity measurements among homologous sequences from the Mammalia class.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1266437314"><span>MicrobesOnline -- Prokaryotic Genome Database</span></a></div><p>Find information about 1000s of microbial genomes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1208461006"><span>Narcisse -- a mirror view of conserved syntenies</span></a></div><p>A database dedicated to the study of genome conservation.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1219772764"><span>OMA -- the Orthologous MAtrix project</span></a></div><p>Explore orthologous relations across 352 complete genomes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1209738741"><span>OPTIC -- orthologous and paralogous transcripts in clades</span></a></div><p>Browse complete genomes in several clades.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1209573208"><span>OrthoDB -- the hierarchical catalog of eukaryotic orthologs</span></a></div><p>Find groups of orthologous genes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1221231200"><span>OrthoMaM -- orthologous mammalian markers</span></a></div><p>A database of orthologous genomic markers for placental mammal phylogenetics.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1100009979"><span>PEDANT -- Protein Extraction, Description and ANalysis Tool</span></a></div><p>Conduct genome wide functional and structural analysis.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1174489475"><span>PReMod -- a database of genome-wide mammalian cis-regulatory module predictions</span></a></div><p>Conduct genome-wide cis-regulatory module (CRM) predictions for both the human and the mouse genomes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1151083092"><span>PhenomicDB -- Comparison of phenotypes of orthologous genes in human and model organisms</span></a></div><p>Compare phenotypes of a given gene or gene set in different model organisms.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1190899370"><span>Phylemon -- A suite of web tools for molecular evolution, phylogenetics and phylogenomics</span></a></div><p>Phylemon is a web server that integrates a selected suite of more than 20 different tools from the most popular stand-alone programs of phylogenetic and evolutionary analysis.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1232555615"><span>PhyloPat -- the phylogenetic pattern database</span></a></div><p>Use this database to see where in the evolution some phylogenetic lineages were started, and over which species they were contained.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1174510223"><span>Pristionchus.org -- a genome-centric database of the nematode satellite species Pristionchus pacificus</span></a></div><p>Search for genomic information on nematode satellite species Pristionchus pacificus.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1236367352"><span>ProtClustDB -- NCBI Protein Clusters Database</span></a></div><p>Find information about related protein sequences.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1209410278"><span>ProtozoaDB -- database of protozoan genomes</span></a></div><p>Database hosting genomics and post-genomics data from multiple protozoans.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1232554690"><span>Pseudofam -- the pseudogene families database</span></a></div><p>A database of pseudogene families based on the protein families from the Pfam database.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL20110518151439"><span>RIDM - RIKEN Integrated Database of Mammals</span></a></div><p>Find genomic information about mammals.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1272562567"><span>RegPrecise -- Regulon Prediction Database</span></a></div><p>Find information about predicted regulons in prokaryotic transcription regulation.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1272477473"><span>SALAD -- Surveyed contained motif ALignment diagram and the Associating Dendrogram</span></a></div><p>Perform systematic comparison of proteome data among species.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1229010765"><span>SGN -- SOL Genomics Network</span></a></div><p>A comparative map viewer dedicated to the biology of the Solanaceae family.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1256669040"><span>ShotgunFunctionalizeR -- R-package for functional comparison of metagenomes</span></a></div><p>Analyze data from functional analysis on fragmented microbial genetic material.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1256238439"><span>SnoopCGH -- Comparative Genomic Hybridization software</span></a></div><p>Visualize and explore comparative genomic hybridization data sets.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1174489598"><span>SwissRegulon -- a database of genome-wide annotations of regulatory sites</span></a></div><p>Search for genome-wide annotations of regulatory sites in yeast and prokaryotes genomes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1229013521"><span>TaxonGap -- a visualization tool for intra- and inter-species variation among individual biomarkers</span></a></div><p>Compare and select individual biomarkers.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1106063477"><span>The Adaptive Evolution Database (TAED) -- a phylogeny based tool for comparative genomics</span></a></div><p>Search for information on adaptive evolution in gene families of higher plants and chordate.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1216742716"><span>The CGView Server -- a comparative genomics tool for circular genomes</span></a></div><p>Generate graphical maps of circular genomes that show sequence features, base composition plots, analysis results and sequence similarity plots.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1099663588"><span>The ERGO -- Genome analysis and discovery system</span></a></div><p>Conduct a comprehensive analysis of genes and genomes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1177611772"><span>The Macaque Genome: Interactive Poster and Teaching Resource</span></a></div><p>An interactive online poster presentation on the Macaque genome, including high-quality images, video clips, and Web resources</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1103816940"><span>The TIGR Gene Indices -- clustering and assembling EST and known genes and integration with eukaryotic genomes</span></a></div><p>Search for annotated genetic information of expressed sequence tags (ESTs) in different eukaryotic organisms.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1043767169"><span>UniGene</span></a></div><p>Find mapping and expression information for a unigene cluster (ESTs and full-length mRNA sequences organized into clusters that each represent a unique known or putative gene)</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1216738072"><span>Uprobe -- universal overgo hybridization-based probe retrieval and design</span></a></div><p>A public online resource for identifying or designing 'universal' overgo-hybridization probes from conserved sequences that can be used to efficiently screen one or more genomic libraries from a designated group of species.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1098205291"><span>VISTA -- Computational Tools for Comparative Genomics</span></a></div><p>Comprehensive suite of programs and databases for comparative analysis of genomic sequences.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL20110518144404"><span>cBARBEL -- Catfish Breeder and Researcher Bioinformatics Entry Location</span></a></div><p>Find information about ictalurid catfish.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1209738040"><span>eggNOG -- evolutionary genealogy of genes: Non-supervised Orthologous Groups</span></a></div><p>Discover orthologous groups of genes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1234370319"><span>metaTIGER -- a metabolic gene evolution resource</span></a></div><p>Find metabolic networks and phylogenomic information on a taxonomically diverse range of eukaryotes.</p></div><div><div><a href="https://www.hsls.pitt.edu/obrc/index.php?page=URL1138901833"><span>xBASE -- a collection of online databases for bacterial comparative genomics</span></a></div><p>Conduct bacterial comparative genomics.</p></div>]]></description>
	<dc:creator>Shruti Paniwala</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/8265/list-of-generic-simulation-softwaretoolsresource-with-brief-description-and-homepage</guid>
	<pubDate>Mon, 10 Feb 2014 05:57:29 -0600</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/8265/list-of-generic-simulation-softwaretoolsresource-with-brief-description-and-homepage</link>
	<title><![CDATA[List of generic simulation software/tools/resource with brief description and homepage !!!]]></title>
	<description><![CDATA[<p>List of generic simulation software/tools/resource with brief description and homepage</p><p><img src="http://www.evolution-of-life.com/fileadmin/images/carousel/genetic.PNG" alt="image" style="border: 0px;"></p><p>ALF <br />A Simulation Framework for Genome Evolution <br />http://www.cbrg.ethz.ch/alf<br /><br />Bayesian Serial SimCoal <br />Bayesian Serial SimCoal, (BayeSSC) is a modification of SIMCOAL 1.0, a program written by Laurent Excoffier, John Novembre, and Stefan Schneider. <br />http://www.stanford.edu/group/hadlylab/ssc/index.html<br /><br />BEERS <br />BEERS was designed to benchmark RNA-Seq alignment algorithms and also algorithms that aim to reconstruct different isoforms and alternate splicing from RNA-Seq data <br />http://cbil.upenn.edu/beers/<br /><br />BOTTLENECK <br />Bottleneck is a program for detecting recent effective population size reductions from allele data frequencies <br />http://www.ensam.inra.fr/urlb/bottleneck/bottleneck.html<br /><br />BottleSim <br />BottleSim is a computer simulation program for simulating the process of population bottlenecks <br />http://chkuo.name/software/bottlesim.html<br /><br />CASS <br />Protein Sequence Simulation <br />http://www.wyomingbioinformatics.org/liberlesgroup/cass/<br /><br />CDPOP <br />CDPOP is a landscape genetics tool for simulating the emergence of spatial genetic structure in populations resulting from specified landscape processes governing organism movement behavior. <br />http://cel.dbs.umt.edu/cdpop<br /><br />CoalFace <br />CoalFace is a simulation of the coalescent process with the visual display of gene genealogies. <br />http://web.up.ac.za/default.asp?ipkcategoryid=3283<br /><br />CoaSim <br />CoaSim is a tool for simulating the coalescent process with recombination and geneconversion under various demographic models. <br />http://users-birc.au.dk/mailund/coasim/index.html<br /><br />cosi <br />The cosi package is written in C and is available as a tar file. <br />http://www.broadinstitute.org/~sfs/cosi/<br /><br />CS-PSeq-Gen <br />A program to simulate the evolution of protein sequences under the constraints of the information of a particular reconstructed phylogeny <br />http://bioserv.rpbs.univ-paris-diderot.fr/software/cs-pseq-gen.html<br /><br />DAWG <br />An application designed to simulate the evolution of recombinant DNA sequences in continuous time <br />http://scit.us/projects/dawg<br /><br />Easypop <br />EASYPOP is an individual based model intended to simulate datasets under a very broad range of conditions <br />http://www.unil.ch/dee/page36926_fr.html<br /><br />EggLib <br />EggLib is a C++/Python library and program package for evolutionary genetics and genomics. <br />http://egglib.sourceforge.net/<br /><br />EvolSimulator <br />A simulation test bed for hypotheses of genome evolution <br />http://acb.qfab.org/acb/evolsim/<br /><br />EvolveAGene <br />A realistic coding sequence simulation program that separates mutation from selection and allows the user to set selection conditions <br />http://bellinghamresearchinstitute.com/software/index.html<br /><br />fastsimcoal <br />A continuous-&not;‐time coalescent simulator of genomic diversity under arbitrarily complex evolutionary scenarios <br />http://cmpg.unibe.ch/software/fastsimcoal/<br /><br />FastSLINK <br />Simulation of Marker and Phenotype Data in Pedigrees <br />http://watson.hgen.pitt.edu/<br /><br />FFPopSim <br />C++/Python library for population genetics. <br />http://webdav.tuebingen.mpg.de/ffpopsim/<br /><br />FLUX SIMULATOR <br />The Flux Simulator aims at providing a deterministic in silico reproduction of the experimental pipelines for RNA-Seq, employing a minimal set of parameters. <br />http://flux.sammeth.net/simulator.html<br /><br />ForSim <br />ForSim: A Forward Evolutionary Computer Simulation <br />http://www.anthro.psu.edu/weiss_lab/research.shtml<br /><br />ForwSim <br />The program given below is based on the algorithm described in Padhukasahasram et al. 2008 to simulate genetic drift in a standard Wright-Fisher process. <br />http://badri-populationgeneticsimulators.blogspot.com/<br /><br />FPG <br />Forward Population Genetic simulation <br />http://genfaculty.rutgers.edu/hey/software#fpg<br /><br />FREGENE <br />FREGENE is a C++ program that simulates sequence-like data over large genomic regions in large diploid populations. <br />http://www.ebi.ac.uk/projects/bargen/download/fregen/documentation_html.html<br /><br />GAMETES <br />Genetic Architecture Model Emulator for Testing and Evaluating Software: Simulates complex SNP models with pure, strict epistatic interactions with n-loci. <br />http://sourceforge.net/projects/gametes/?source=navbar<br /><br />GASP <br />Genometric Analysis Simulation Program. A software tool for testing and investigating methods in statistical genetics by generating samples of family data based on user specified models. <br />http://research.nhgri.nih.gov/gasp/<br /><br />GemSIM <br />Next generation sequencing read simulator <br />http://sourceforge.net/projects/gemsim/<br /><br />GeneArtisan <br />Simulation of Markers in Case-Control Study Designs <br />http://www.rannala.org/?page_id=241<br /><br />GENOME <br />A rapid coalescent-based whole genome simulator <br />http://www.sph.umich.edu/csg/liang/genome/<br /><br />GenomePop2 <br />GenomePop2 is a specialization of the program GenomePop just to manage SNPs under more flexible and useful settings. If you need models with more than 2 alleles please use the GenomePop program version. <br />http://webs.uvigo.es/acraaj/genomepop2.htm<br /><br />GenomeSimla <br />GenomeSIMLA is currently under development- however, we have a beta release that we are asking to be tested <br />http://chgr.mc.vanderbilt.edu/genomesimla/<br /><br />GENS2 <br />Simulates interactions among two genetic and one environmental factor and also allows for epistatic interactions. <br />https://sourceforge.net/projects/gensim/<br /><br />GWAsimulator <br />A rapid whole genome simulation program <br />http://biostat.mc.vanderbilt.edu/wiki/main/gwasimulator<br /><br />HAP-SAMPLE <br />An association simulator for candidate regions or genome scans <br />http://www.hapsample.org/<br /><br />HAPGEN <br />A simulator for the simulation of case control datasets at SNP markers <br />https://mathgen.stats.ox.ac.uk/genetics_software/hapgen/hapgen2.html<br /><br />HapSim <br />A simulation tool for generating haplotype data with pre-specified allele frequencies and LD coefficients <br />http://cran.r-project.org/web/packages/hapsim/index.html<br /><br />HAPSIMU <br />A program that simulates heterogeneous populations with various known and controllable structures under the continuous migration model or the discrete model <br />http://l.web.umkc.edu/liujian/<br /><br />IBDsim <br />IBDSim is a computer package for the simulation of genotypic data under general isolation by distance models. <br />http://raphael.leblois.free.fr/<br /><br />indel-Seq-Gen <br />A biological sequence simulation program that simulates highly divergent DNA sequences and protein superfamilies <br />http://bioinfolab.unl.edu/~cstrope/isg/<br /><br />Indelible <br />A powerful and flexible simulator of biological evolution <br />http://abacus.gene.ucl.ac.uk/software/indelible/<br /><br />invertFREGENE <br />InvertFREGENE is a forward-in-time simulator of inversions in population genetic data <br />http://www.ebi.ac.uk/projects/bargen/<br /><br />kernalPop <br />A spatially explicit population genetic simulation engine <br />http://cran.r-project.org/src/contrib/archive/kernelpop/<br /><br />MaCS <br />Markovian Coalescent Simulator <br />http://www-hsc.usc.edu/~garykche/<br /><br />Mason <br />A package for the simulation of nucleotide data. <br />http://www.seqan.de/projects/mason/<br /><br />mbs <br />modifying Hudson's ms software to generate samples of DNA sequences with a biallelic site under selection <br />http://www.sendou.soken.ac.jp/esb/innan/innanlab/software.html<br /><br />Mendel's Accountant <br />Mendel's Accountant (MENDEL) is an advanced numerical simulation program for modeling genetic change over time and was developed collaboratively by Sanford, Baumgardner, Brewer, Gibson and ReMine <br />http://mendelsaccount.sourceforge.net/<br /><br />MetaSim <br />A tool to generate collections of synthetic reads that reflect the diverse taxonomical composition of typical metagenome data sets <br />http://ab.inf.uni-tuebingen.de/software/metasim/<br /><br />mlcoalsim <br />Multilocus Coalescent Simulations <br />http://code.google.com/p/mlcoalsim-v1/<br /><br />ms <br />The purpose of this program is to allow one to investigate the statistical properties of such samples, to evaluate estimators or statistical tests, and generally to aid in the interpretation of polymorphism data sets. <br />http://home.uchicago.edu/~rhudson1/source/mksamples.html<br /><br />msHOT <br />The purpose of this program is to allow one to investigate the statistical properties of such samples, to evaluate estimators or statistical tests, and generally to aid in the interpretation of polymorphism data sets. <br />http://home.uchicago.edu/~rhudson1/<br /><br />msms <br />A coalescent Simlation tool with selection. <br />http://www.mabs.at/ewing/msms/index.shtml<br /><br />MySSP <br />A program for the simulation of DNA sequence evolution across a phylogenetic tree <br />http://www.rosenberglab.net/software.php<br /><br />Nemo <br />A forward-time, individual-based, genetically explicit, and stochastic simulation program designed to study the evolution of genetic markers, life history traits, and phenotypic traits in a flexible (meta-)population framework. <br />http://nemo2.sourceforge.net/<br /><br />NetRecodon <br />Coalescent simulation of coding DNA sequences with recombination (inter and intracodon), migration and demography <br />http://code.google.com/p/netrecodon/<br /><br />PEDAGOG <br />Software for simulating eco-evolutionary population dynamics <br />https://bcrc.bio.umass.edu/pedigreesoftware/node/5<br /><br />phenosim <br />A tool to add phenotypes to simulated genotypes <br />http://evoplant.uni-hohenheim.de/doku.php?id=software:software<br /><br />PhyloSim <br />An R package for the Monte Carlo simulation of sequence evolution <br />http://bit.ly/rlsim-git<br /><br />pIRS <br />Profile-based Illumina pair-end reads simulator <br />https://code.google.com/p/pirs/<br /><br />ProteinEvolver <br />Simulation of protein evolution along phylogenies under structure-based substitution models <br />http://code.google.com/p/proteinevolver/<br /><br />QMSim <br />QTL and Marker Simulator <br />http://www.aps.uoguelph.ca/~msargol/qmsim/<br /><br />quantiNEMO <br />An individual-based program for the analysis of quantitative traits with explicit genetic architecture potentially under selection in a structured population <br />http://www2.unil.ch/popgen/softwares/quantinemo/<br /><br />RECOAL <br />Simulates new haplotype data from a reference population of haplotypes. <br />ftp://popgen.usc.edu/<br /><br />Recodon <br />Coalescent simulation of coding DNA sequences with recombination, migration and demography <br />http://code.google.com/p/recodon/<br /><br />rlsim <br />A package for simulating RNA-seq library preparation with parameter estimation <br />http://bit.ly/rlsim-git<br /><br />Rmetasim <br />Rmetasim is a front-end for the metasim engine that is implemented as a package that runs in the statistical computing environment R <br />http://linum.cofc.edu/software.html#metasim<br /><br />RNA Seq Simulator <br />RSS takes SAM alignment files from RNA-Seq data and simulates over dispersed, multiple replica, differential, non-stranded RNA-Seq datasets. <br />http://useq.sourceforge.net/cmdlnmenus.html#rnaseqsimulator<br /><br />Rose <br />Random model of sequence evolution <br />http://bibiserv.techfak.uni-bielefeld.de/rose/<br /><br />SelSim <br />SelSim is a program for Monte Carlo simulation of DNA polymorphism data for a recom- bining region within which a single bi-allelic site has experienced natural selection <br />http://www.well.ox.ac.uk/~spencer/selsim/<br /><br />Seq-Gen <br />An application for the Monte Carlo simulation of molecular sequence evolution along phylogenetic trees. <br />http://tree.bio.ed.ac.uk/software/seqgen/<br /><br />SEQPower <br />Statistical power analysis for sequence-based association studies <br />http://bioinformatics.org/spower/<br /><br />SeqSIMLA <br />SeqSIMLA can simulate sequence data with user-specified disease and quantitative trait models. Family or unrelated case-control data can be simulated. <br />http://seqsimla.sourceforge.net/<br /><br />Serial NetEvolve <br />A flexible utility for generating serially-sampled sequences along a tree or recombinant network <br />http://biorg.cis.fiu.edu/sne/<br /><br />SFS_CODE <br />SFS_CODE can perform forward population genetic simulations under a general Wright-Fisher model with arbitrary migration, demographic, selective, and mutational effects. <br />http://sfscode.sourceforge.net/sfs_code/index/index.html<br /><br />SIBSIM <br />Quantitative phenotype simulation in extended pedigrees <br />http://sourceforge.net/projects/sibsim/<br /><br />SIMCOAL2 <br />A coalescent program for the simulation of complex recombination patterns over large genomic regions under various demographic models <br />http://cmpg.unibe.ch/software/simcoal2/<br /><br />SimCopy <br />An R package simulating the evolution of copy number profiles along a tree. <br />http://bit.ly/simcopy<br /><br />SIMLA <br />SIMLA is a SIMuLAtion program that generates data sets of families for use in Linkage and Association studies. <br />http://www.chg.duke.edu/research/simla.html<br /><br />SimPed <br />A Simulation Program to Generate Haplotype and Genotype Data for Pedigree Structures <br />http://www.hgsc.bcm.tmc.edu/content/simped<br /><br />Simprot <br />A program to simulate protein evolution by substitution, insertion and deletion <br />http://www.uhnresearch.ca/labs/tillier/software.htm#3<br /><br />SimRare <br />Rare variant simulation and analysis tool <br />http://code.google.com/p/simrare/<br /><br />simuGWAS <br />A forward-time simulator that simulates realistic samples for genome-wide association studies. <br />http://simupop.sourceforge.net/cookbook/simucomplexdisease<br /><br />simuPOP <br />simuPOP is a general-purpose individual-based forward-time population genetics simulation environment. <br />http://simupop.sourceforge.net/<br /><br />SISSI <br />A software tool to generate data of related sequences along a given phylogeny, taking into account user defined system of neighbourhoods and instantaneous rate matrices. <br />http://www.cibiv.at/software/sissi/<br /><br />SNPsim <br />Coalescent simulation of hotspot recombination <br />http://code.google.com/p/phylosoftware/<br /><br />SPIP <br />SPIP simulates the transmission of genes from parents to offspring in a population having demographic structure defined by the user <br />http://swfsc.noaa.gov/textblock.aspx?division=fed&amp;id=3434<br /><br />Splatche <br />Spatial and Temporal Coalescences in Heterogeneous Environment <br />http://www.splatche.com/<br /><br />srv <br />Simulator of Rare Varaints (srv) is a simulator for the simulation of the introduction and evolution of (rare) genetic variants. <br />http://simupop.sourceforge.net/cookbook/simurarevariants<br /><br />SUP <br />SLINK/FastSLINK utility program <br />http://mlemire.freeshell.org/software.html<br /><br />TreesimJ <br />A flexible, forward-time population genetic simulator <br />http://code.google.com/p/treesimj/<br /><br />Vortex <br />VORTEX is an individual-based simulation model for population viability analysis (PVA). <br />http://www.vortex9.org/vortex.html<br /><br />References:</p><p>Image www.evolution-of-life.com</p><p>www.cancer.gov</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41442/gsp4pdb-a-web-tool-to-visualize-search-and-explore-protein-ligand-structural-patterns</guid>
	<pubDate>Sun, 15 Mar 2020 03:41:12 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41442/gsp4pdb-a-web-tool-to-visualize-search-and-explore-protein-ligand-structural-patterns</link>
	<title><![CDATA[GSP4PDB: a web tool to visualize, search and explore protein-ligand structural patterns]]></title>
	<description><![CDATA[<p><span><span>GSP4PDB is a user-friendly and efficient application to search and discover new patterns of protein-ligand interaction.</span></span></p>
<p><span>GSP4PDB</span><span>&nbsp;is part of the services provided by the&nbsp;</span><a href="https://structuralbio.utalca.cl/" target="_blank">Bioinformatic Group</a><span>&nbsp;of the&nbsp;</span><a href="http://www.utalca.cl/" target="_blank">University of Talca</a></p>
<p><a href="http://gdblab.com/gsp4pdb/gsp4pdb2/">http://gdblab.com/gsp4pdb/gsp4pdb2/</a></p>
<p>https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-020-3352-x</p><p>Address of the bookmark: <a href="http://gdblab.com/gsp4pdb/gsp4pdb2/" rel="nofollow">http://gdblab.com/gsp4pdb/gsp4pdb2/</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/11611/ten-recommendations-for-creating-usable-bioinformatics-command-line-software</guid>
	<pubDate>Sun, 08 Jun 2014 10:06:26 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/11611/ten-recommendations-for-creating-usable-bioinformatics-command-line-software</link>
	<title><![CDATA[Ten recommendations for creating usable bioinformatics command line software]]></title>
	<description><![CDATA[<p><span>Bioinformatics software varies greatly in quality. In terms of usability, the command line interface is the first experience a user will have of a tool. Unfortunately, this is often also the last time a tool will be used. Here I present ten recommendations for command line software author&rsquo;s tools to follow, which I believe would greatly improve the uptake and usability of their products, waste less user&rsquo;s time, and improve the quality of scientific analyses.</span></p><p>Address of the bookmark: <a href="http://www.gigasciencejournal.com/content/2/1/15?utm_content=buffer25ee0&amp;utm_medium=social&amp;utm_source=twitter.com&amp;utm_campaign=buffer" rel="nofollow">http://www.gigasciencejournal.com/content/2/1/15?utm_content=buffer25ee0&amp;utm_medium=social&amp;utm_source=twitter.com&amp;utm_campaign=buffer</a></p>]]></description>
	<dc:creator>RAJESH DETROJA</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/19636/google-genomics</guid>
	<pubDate>Thu, 18 Dec 2014 11:05:42 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/19636/google-genomics</link>
	<title><![CDATA[Google Genomics]]></title>
	<description><![CDATA[<ul>
<li>
<p><strong>Explore genetic variation interactively.</strong> Compare entire cohorts in seconds with SQL-like queries. Compute transition/transversion ratios, genome-wide association, allelic frequency and more.</p>
</li>
<li>
<p><strong>Process big genomic data easily.</strong> Run batch analyses like principal component analysis and Hardy-Weinberg equilibrium on as many samples as you like, in minutes or hours, with just a little code.</p>
</li>
<li>
<p><strong>Use Google's infrastructure and big data expertise.</strong> Store one genome or a million using Google Genomics and take advantage of the same infrastructure that powers Search, Maps, YouTube, Gmail and Drive.</p>
</li>
<li>
<p><strong>Support emerging global standards.</strong> Google Genomics is implementing the API defined by the Global Alliance for Genomics and Health for visualization, analysis and more. Compliant software can access Google Genomics, local servers, or any other implementation.</p>
</li>
</ul><p>Address of the bookmark: <a href="https://cloud.google.com/genomics/" rel="nofollow">https://cloud.google.com/genomics/</a></p>]]></description>
	<dc:creator>Tenzin Paul</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32379/enrichr-a-comprehensive-gene-set-enrichment-analysis</guid>
	<pubDate>Thu, 27 Apr 2017 05:42:09 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32379/enrichr-a-comprehensive-gene-set-enrichment-analysis</link>
	<title><![CDATA[Enrichr: a comprehensive gene set enrichment analysis]]></title>
	<description><![CDATA[<p><span>Enrichment analysis is a popular method for analyzing gene sets generated by genome-wide experiments. Here we present a significant update to one of the tools in this domain called Enrichr. Enrichr currently contains a large collection of diverse gene set libraries available for analysis and download. In total, Enrichr currently contains 180 184 annotated gene sets from 102 gene set libraries. New features have been added to Enrichr including the ability to submit fuzzy sets, upload BED files, improved application programming interface and visualization of the results as clustergrams. Overall, Enrichr is a comprehensive resource for curated gene sets and a search engine that accumulates biological knowledge for further biological discoveries. Enrichr is freely available at:&nbsp;</span><a href="http://amp.pharm.mssm.edu/Enrichr" target="">http://amp.pharm.mssm.edu/Enrichr</a><span>.</span></p>
<p>https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkw377</p><p>Address of the bookmark: <a href="http://amp.pharm.mssm.edu/Enrichr/" rel="nofollow">http://amp.pharm.mssm.edu/Enrichr/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/43563/apache-server-setting</guid>
	<pubDate>Fri, 29 Oct 2021 04:29:51 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/43563/apache-server-setting</link>
	<title><![CDATA[Apache server setting !]]></title>
	<description><![CDATA[<p>Apache is an open source web server that&rsquo;s available for Linux servers free of charge.</p>
<p>In this tutorial we&rsquo;ll be going through the steps of setting up an Apache server.</p>
<h3>What you&rsquo;ll learn</h3>
<ul>
<li>How to set up Apache</li>
<li>Some basic Apache configuration</li>
</ul><p>Address of the bookmark: <a href="https://ubuntu.com/tutorials/install-and-configure-apache#3-creating-your-own-website" rel="nofollow">https://ubuntu.com/tutorials/install-and-configure-apache#3-creating-your-own-website</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/44206/heatmap-draw</guid>
	<pubDate>Mon, 06 Mar 2023 04:24:57 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/44206/heatmap-draw</link>
	<title><![CDATA[Heatmap Draw !]]></title>
	<description><![CDATA[<p>Server for heatmap generation !</p>
<p>https://software.broadinstitute.org/morpheus/</p><p>Address of the bookmark: <a href="https://software.broadinstitute.org/morpheus/" rel="nofollow">https://software.broadinstitute.org/morpheus/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/37965/kobas-a-web-server-for-geneprotein-functional-annotation-and-functional-gene-set-enrichment</guid>
	<pubDate>Fri, 19 Oct 2018 09:36:11 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/37965/kobas-a-web-server-for-geneprotein-functional-annotation-and-functional-gene-set-enrichment</link>
	<title><![CDATA[KOBAS: a web server for gene/protein functional annotation and functional gene set enrichment]]></title>
	<description><![CDATA[<p><span>KOBAS 3.0 is a web server for gene/protein functional annotation (</span><a href="http://kobas.cbi.pku.edu.cn/annotate.php">Annotate</a><span>&nbsp;module) and functional gene set enrichment(Enrichment module). For Annotate module, it accepts gene list as input, including IDs or sequences, and generates annotations for each gene based on multiple databases about pathways, diseases, and Gene Ontology. For Enrichment module, it can accept either gene list or gene expression data as input, and generates enriched gene sets, corresponding name, p-value or a probability of enrichment and enrichment score based on results of multiple methods.</span></p><p>Address of the bookmark: <a href="http://kobas.cbi.pku.edu.cn/" rel="nofollow">http://kobas.cbi.pku.edu.cn/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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