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<channel>
	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/44472?offset=160</link>
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	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27257/busco-assessing-genome-assembly-and-annotation-completeness-with-benchmarking-universal-single-copy-orthologs</guid>
	<pubDate>Tue, 10 May 2016 07:46:24 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27257/busco-assessing-genome-assembly-and-annotation-completeness-with-benchmarking-universal-single-copy-orthologs</link>
	<title><![CDATA[BUSCO: Assessing genome assembly and annotation completeness with Benchmarking Universal Single-Copy Orthologs]]></title>
	<description><![CDATA[<ul>
<li><span>High-throughput genomics has revolutionized biological research, however, while the number of sequenced genomes grows by the day, quality assessment of the resulting assembled sequences remains complicated and mostly limited to technical measures like N50.&nbsp;</span></li>
<li></li>
<li><span>BUSCO provides measures for quantitative assessment of genome assembly, gene set, and transcriptome completeness based on evolutionarily informed expectations of gene content from near-universal single-copy orthologs selected from&nbsp;</span><a href="http://orthodb.org/">OrthoDB</a><span>.&nbsp;</span></li>
<li></li>
<li><span>BUSCO assessments are implemented in open-source software, with comprehensive lineage-specific sets of Benchmarking Universal Single-Copy Orthologs for arthropods, vertebrates, metazoans, fungi, eukaryotes, and bacteria.&nbsp;</span></li>
<li></li>
<li><span>These conserved orthologs are ideal candidates for large-scale phylogenomics studies, and the annotated BUSCO gene models built during genome assessments provide a comprehensive gene predictor training set for use as part of genome annotation pipelines.&nbsp;</span></li>
<li></li>
<li><span>BUSCO assessments offer intuitive metrics, based on evolutionarily informed expectations of gene content from hundreds of species, to gauge completeness of rapidly accumulating genomic data and satisfy an Iberian's quest for quality - "Busco calidad/qualidade".</span></li>
</ul><p>Address of the bookmark: <a href="http://busco.ezlab.org/" rel="nofollow">http://busco.ezlab.org/</a></p>]]></description>
	<dc:creator>Anjana</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27080/mrfast-micro-read-fast-alignment-search-tool</guid>
	<pubDate>Tue, 26 Apr 2016 03:50:06 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27080/mrfast-micro-read-fast-alignment-search-tool</link>
	<title><![CDATA[mrFAST:  Micro Read Fast Alignment Search Tool]]></title>
	<description><![CDATA[<p><span>mrFAST is a read mapper that is designed to map short reads to reference genome with a special emphasis on the discovery of structural variation and segmental duplications. mrFAST maps short reads with respect to user defined error threshold, including indels up to 4+4 bp. This manual, describes how to choose the parameters and tune mrFAST with respect to the library settings. mrFAST is designed to find&nbsp;</span><strong><span style="text-decoration: underline;">'all'</span></strong><span>&nbsp; mappings for a given set of reads, however it can return one "best" map location if the relevant parameter is invoked.</span></p>
<p><span>More at&nbsp;http://mrfast.sourceforge.net/manual.html</span></p><p>Address of the bookmark: <a href="http://mrfast.sourceforge.net/manual.html" rel="nofollow">http://mrfast.sourceforge.net/manual.html</a></p>]]></description>
	<dc:creator>Neel</dc:creator>
</item>

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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/27211/srbioinformatics-analyst-ngs-ocimumbio</guid>
  <pubDate>Mon, 02 May 2016 04:41:22 -0500</pubDate>
  <link></link>
  <title><![CDATA[Sr.Bioinformatics Analyst (NGS) @ OcimumBio]]></title>
  <description><![CDATA[
<p>Sr.Bioinformatics Analyst (NGS)</p>

<p>Experience Required: 3-5 years of experience<br />No of Positions : Multiple<br />Qualifications: Candidates with minimum qualification as M.Sc Bioinformatics with 3-5  years of experience in Life sciences R&amp;D or Pharma Industry.<br />Ph.D candidates with research experience in Bioinformatics with publications in International journal and minimum 2 years of  industry experience in clinical genomics will be preferred for this position.</p>

<p>Requirement:</p>

<p>1.  Must have basic understanding of molecular biology and Genomics.<br />2. Experience in application development or must have expertise in programming using either of Perl/Python.<br />3.  Experience in statistical programming using R/Bioconductor/Matlab.<br />4. Strong concept in statistical and mathematical modelling.<br />5.  Experience in designing and developing the bioinformatics pipeline.<br />6.  Must have minimum 2+ years of hands on experience in NSG data analysis such as RNA-Seq,Exome-Seq ,Chip-Seq and downstream analysis.<br />7. Knowledge in WGS ,WES, Targeted re-sequencing,GWAS and population genomics will be preferred.<br />8. Must have experience working on opensource software/Framework and commercial software for NGS data analysis and reporting.<br />9. Should be aware of handling big data and guiding team members on multiple projects simultaneously.<br />More at http://www.ocimumbio.com/careers1/<br />10. Should have experience coordinating with different groups of clinical research scientist for various project requirements.<br />11. Ability to work as team as well as independently with minimal support.</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27261/segemehl</guid>
	<pubDate>Tue, 10 May 2016 08:10:15 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27261/segemehl</link>
	<title><![CDATA[segemehl]]></title>
	<description><![CDATA[<p><span>segemehl is a software to map short sequencer reads to reference genomes. Unlike other methods, segemehl is able to detect not only mismatches but also insertions and deletions. Furthermore, segemehl is not limited to a specific read length and is able to map&nbsp;primer- or polyadenylation contaminated reads correctly.&nbsp; segemehl implements a matching strategy based on enhanced suffix arrays (ESA).&nbsp;</span></p>
<p><span>More at&nbsp;http://www.bioinf.uni-leipzig.de/Software/segemehl/</span></p>
<p><span>Manual&nbsp;http://www.bioinf.uni-leipzig.de/Software/segemehl/segemehl_manual_0_1_7.pdf</span></p><p>Address of the bookmark: <a href="http://hoffmann.bioinf.uni-leipzig.de/LIFE/segemehl.html" rel="nofollow">http://hoffmann.bioinf.uni-leipzig.de/LIFE/segemehl.html</a></p>]]></description>
	<dc:creator>Anjana</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/27235/supposedly-educational-r</guid>
	<pubDate>Tue, 03 May 2016 16:43:08 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/27235/supposedly-educational-r</link>
	<title><![CDATA[Supposedly Educational R]]></title>
	<description><![CDATA[<p>R 3.3.0 (codename &ldquo;Supposedly Educational&rdquo;)&nbsp;was <a href="http://r.789695.n4.nabble.com/R-3-3-0-is-released-td4720368.html" target="_blank">released today</a>.&nbsp;You can get the latest binaries version <strong><a href="http://cran.rstudio.com/" target="_blank">from here</a>.</strong>&nbsp;(or the .tar.gz&nbsp;<strong>source</strong> code from <a href="http://cran.r-project.org/src/base/R-3/R-3.3.0.tar.gz" target="_blank">here</a>).&nbsp;The full list of new features and bug fixes is provided below.</p><p>If you are using <strong>Windows&nbsp;</strong>you can easily upgrade to the latest version of R using <a href="http://cran.r-project.org/web/packages/installr/" target="_blank">the installr package</a>. Simply run the following code in Rgui:</p><div><table width="710">
<tbody>
<tr id="p613882">
<td id="p61388code2">
<pre><span style="color: #0000ff; font-weight: bold;">install.<span>packages</span></span><span style="color: #080;">(</span><span style="color: #ff0000;">"installr"</span><span style="color: #080;">)</span> <span style="color: #228b22;"># install </span>
setInternet2<span style="color: #080;">(</span>TRUE<span style="color: #080;">)</span>
installr<span style="color: #080;">::</span><span>updateR</span><span style="color: #080;">(</span><span style="color: #080;">)</span> <span style="color: #228b22;"># updating R.</span></pre>
</td>
</tr>
</tbody>
</table></div><p><span>Running &ldquo;updateR()&rdquo; will detect if there is a new R version available, and if so it will download+install it (etc.). There is also <a href="http://www.r-statistics.com/2015/06/a-step-by-step-screenshots-tutorial-for-upgrading-r-on-windows/" target="_blank">a&nbsp;step by step tutorial (with screenshots) on how to upgrade R on Windows, using the <em>installr</em></a>&nbsp;package. If you only see the option to upgrade to an older version of R, then change your mirror or try again in a few hours (it usually take around 24 hours for all CRAN mirrors to get the latest version of R).</span></p><p><em>I try to keep the <a href="https://github.com/talgalili/installr" target="_blank">installr</a> package updated and useful, so if you have any suggestions or remarks on the package &ndash; you are invited to <a href="https://github.com/talgalili/installr/issues" target="_blank">open an issue in the github page</a>.</em></p>]]></description>
	<dc:creator>Rahul Nayak</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/27250/lawley-lab</guid>
  <pubDate>Mon, 09 May 2016 03:29:51 -0500</pubDate>
  <link></link>
  <title><![CDATA[Lawley Lab]]></title>
  <description><![CDATA[
<p>Lawley Lab are covered with a complex microbial community, known as our microbiota, which plays important roles in our physiology, immunity, metabolism and sustenance. Within the human gastrointestinal tract alone there are over 1,000 bacterial species, which amounts to approximately 10 times more cells than we harbor in our entire body and 200 times more genes than are found within our genome. Lawley Lab are really a 'supraorganism' consisting of our 'human' and 'microbial' selves.</p>

<p>More at http://www.sanger.ac.uk/science/groups/lawley-lab</p>
]]></description>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/27311/release-notes-for-genome-workbench-2105</guid>
	<pubDate>Thu, 12 May 2016 13:49:41 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/27311/release-notes-for-genome-workbench-2105</link>
	<title><![CDATA[Release Notes for Genome Workbench 2.10.5]]></title>
	<description><![CDATA[<p>New Features in latest release</p><ul>
<li>New ProSplign tool integrated with Genome Workbench (<a href="https://www.ncbi.nlm.nih.gov/tools/gbench/tutorial13">Tutorial</a>,&nbsp;<a href="https://www.youtube.com/watch?v=V9UqKJprzAg&amp;feature=youtu.be" target="_blank">Video</a>)</li>
<li>New export function for BAM/cSRA coverage graphs (<a href="https://www.ncbi.nlm.nih.gov/tools/gbench/tutorial14">Tutorial</a>)</li>
<li>New export function for alignments GFF3 format ((<a href="https://www.ncbi.nlm.nih.gov/tools/gbench/tutorial15">Tutorial</a>))</li>
<li>Tree View: implemented new export mode based on selections (tutorial coming)</li>
<li>Tree View: added support for&nbsp;<a href="https://www.ncbi.nlm.nih.gov/tools/gbench/tutorial3/#distance_based_circular_trees">distance based circular trees</a></li>
<li>Tree View: new rooting mode (Midpoint Root) results in more balanced trees (<a href="https://www.ncbi.nlm.nih.gov/tools/gbench/tutorial3#reroot_tree">Tutorial</a>)</li>
<li>Tree View: added possibility to right-click on an edge between two nodes and "Place Root at Middle of Branch" &ndash; to re-root at mid-branch (<a href="https://www.ncbi.nlm.nih.gov/tools/gbench/tutorial3#reroot_tree">Tutorial</a>)</li>
</ul>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27323/cutadapt</guid>
	<pubDate>Fri, 13 May 2016 04:54:50 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27323/cutadapt</link>
	<title><![CDATA[cutadapt]]></title>
	<description><![CDATA[<p>Cutadapt finds and removes adapter sequences, primers, poly-A tails and other types of unwanted sequence from your high-throughput sequencing reads.</p>
<p>Cleaning your data in this way is often required: Reads from small-RNA sequencing contain the 3&rsquo; sequencing adapter because the read is longer than the molecule that is sequenced. Amplicon reads start with a primer sequence. Poly-A tails are useful for pulling out RNA from your sample, but often you don&rsquo;t want them to be in your reads.</p>
<p>Cutadapt helps with these trimming tasks by finding the adapter or primer sequences in an error-tolerant way. It can also modify and filter reads in various ways. Adapter sequences can contain IUPAC wildcard characters. Also, paired-end reads and even colorspace data is supported. If you want, you can also just demultiplex your input data, without removing adapter sequences at all.</p>
<p>Cutadapt comes with an extensive suite of automated tests and is available under the terms of the MIT license.</p>
<p>If you use cutadapt, please cite <a href="http://dx.doi.org/10.14806/ej.17.1.200">DOI:10.14806/ej.17.1.200</a> .</p><p>Address of the bookmark: <a href="https://cutadapt.readthedocs.io/en/stable/installation.html#quickstart" rel="nofollow">https://cutadapt.readthedocs.io/en/stable/installation.html#quickstart</a></p>]]></description>
	<dc:creator>Radha Agarkar</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/27344/orffinder-with-smart-blast</guid>
	<pubDate>Tue, 17 May 2016 01:43:15 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/27344/orffinder-with-smart-blast</link>
	<title><![CDATA[ORFfinder with smart BLAST]]></title>
	<description><![CDATA[<p><span>ORF Finder</span></p><p><span><a href="http://www.ncbi.nlm.nih.gov/orffinder">ORFfinder</a><span>&nbsp;is a graphical analysis tool for finding open reading frames (ORFs). We&rsquo;ve been working on a few updates, and we&rsquo;d like to find out what you think about them. Read on to find out what you can do with the new ORFfinder.</span></span></p><p>Smart BLAST (https://ncbiinsights.ncbi.nlm.nih.gov/2015/07/29/smartblast/)</p><p>Select one or a group of ORFs and BLAST several databases at once, and use the newly developed&nbsp;<a href="http://blast.ncbi.nlm.nih.gov/smartblast/">SmartBLAST</a>&nbsp;to verify protein names.&nbsp;Looking for the traditional results from&nbsp;<a href="http://blast.ncbi.nlm.nih.gov/Blast.cgi">BLAST</a>? They&rsquo;re there too.</p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27427/rcircos-an-r-package-for-circos-2d-track-plots</guid>
	<pubDate>Fri, 20 May 2016 11:01:13 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27427/rcircos-an-r-package-for-circos-2d-track-plots</link>
	<title><![CDATA[RCircos: an R package for Circos 2D track plots]]></title>
	<description><![CDATA[<p>RCircos package provides a simple and flexible way to make Circos 2D track plots with R and could be easily integrated into other R data processing and graphic manipulation pipelines for presenting large-scale multi-sample genomic research data. It can also serve as a base tool to generate complex Circos images.</p>
<p>More at https://bitbucket.org/henryhzhang/rcircos/src</p><p>Address of the bookmark: <a href="https://bitbucket.org/henryhzhang/rcircos/src" rel="nofollow">https://bitbucket.org/henryhzhang/rcircos/src</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

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