https://www.hiv.lanl.gov/components/sequence/HIV/search/search.html

Address of the bookmark: https://www.hiv.lanl.gov/components/sequence/HIV/search/search.html

The enzyme portal integrates many resources, most of them hosted by EBI and also external ones such as BioPortal. Its main goal is to provide information about enzymes in a suitable format, with a usable interface designed for intended users. Instead of reinventing the wheel, it makes use of available and reliable resources to that end.

Related Literature:

http://nar.oxfordjournals.org/content/41/D1/D773.full

http://www.biomedcentral.com/1471-2105/14/103

Address of the bookmark: http://www.ebi.ac.uk/enzymeportal/

https://link.springer.com/epdf/10.1186/s12864-018-5330-5?author_access_token=ICASEpyMAQaxLlKw--fyCG_BpE1tBhCbnbw3BuzI2RMA57KLmXk5bZabRUiDQzRFHXd6hjm4kWSiLV3mU5XVMitqXUwFMSo4x5vbfty0EDQ9PW1sd1h923_TYXkvJ5niSwAyZ7BklJ0ujFAFhcKtjw%3D%3D

Address of the bookmark: https://webs.iiitd.edu.in/raghava/humcfs/

More at https://software.broadinstitute.org/gatk/download/bundle

ftp://ftp.ncbi.nlm.nih.gov/snp/organisms/human_9606/VCF/GATK/.

ftp://ftp.broadinstitute.org/bundle/hg38/hg38bundle/

Address of the bookmark: https://console.cloud.google.com/storage/browser/genomics-public-data/resources/broad/hg38/v0?pli=1

More recently, we've been enthused about using k-mer based similarity measures and computing and searching k-mer-based sketch search databases for all the things.

But I haven't spent too much talking about using k-mers for taxonomy, although that has become an ahem area of interest recently, if you read into our papers a bit.

In this blog post I'm going to fix this by doing a little bit of a literature review and waxing enthusiastic about other people's work. Then in a future blog post I'll talk about how we're building off of this work in fun! and interesting? ways!

Address of the bookmark: http://ivory.idyll.org/blog/2017-something-about-kmers.html

General information.

Field terminator is "\t|\t"

Row terminator is "\t|\n"

nodes.dmp file consists of taxonomy nodes. The description for each node includes the following

fields:

tax_id -- node id in GenBank taxonomy database

  parent tax_id -- parent node id in GenBank taxonomy database

  rank -- rank of this node (superkingdom, kingdom, ...) 

  embl code -- locus-name prefix; not unique

  division id -- see division.dmp file

  inherited div flag  (1 or 0) -- 1 if node inherits division from parent

  genetic code id -- see gencode.dmp file

  inherited GC  flag  (1 or 0) -- 1 if node inherits genetic code from parent

  mitochondrial genetic code id -- see gencode.dmp file

  inherited MGC flag  (1 or 0) -- 1 if node inherits mitochondrial gencode from parent

  GenBank hidden flag (1 or 0)            -- 1 if name is suppressed in GenBank entry lineage

  hidden subtree root flag (1 or 0)       -- 1 if this subtree has no sequence data yet

  comments -- free-text comments and citations

Taxonomy names file (names.dmp):

tax_id -- the id of node associated with this name

name_txt -- name itself

unique name -- the unique variant of this name if name not unique

name class -- (synonym, common name, ...)

Divisions file (division.dmp):

division id -- taxonomy database division id

division cde -- GenBank division code (three characters)

division name -- e.g. BCT, PLN, VRT, MAM, PRI...

comments

Genetic codes file (gencode.dmp):

genetic code id -- GenBank genetic code id

abbreviation -- genetic code name abbreviation

name -- genetic code name

cde -- translation table for this genetic code

starts -- start codons for this genetic code

Deleted nodes file (delnodes.dmp):

tax_id -- deleted node id

Merged nodes file (merged.dmp):

old_tax_id                              -- id of nodes which has been merged

new_tax_id                              -- id of nodes which is result of merging

Citations file (citations.dmp):

cit_id -- the unique id of citation

cit_key -- citation key

pubmed_id -- unique id in PubMed database (0 if not in PubMed)

medline_id -- unique id in MedLine database (0 if not in MedLine)

url -- URL associated with citation

text -- any text (usually article name and authors).

-- The following characters are escaped in this text by a backslash:

-- newline (appear as "\n"),

-- tab character ("\t"),

-- double quotes ('\"'),

-- backslash character ("\\").

taxid_list -- list of node ids separated by a single space

For example, you can run a search in Assembly and use check boxes (see left side of screenshot below) to refine the set of genome assemblies of interest. Then, just open the “Download assemblies” menu, choose the source database (GenBank or RefSeq), choose the file type, and start the download. An archive file will be saved to your computer that can be expanded into a folder containing your selected genome data files.

More at https://ncbiinsights.ncbi.nlm.nih.gov/2017/05/08/genome-data-download-made-easy/

he CMG-biotools system presents a stand-alone interface for comparative microbial genomics. The package is a customized operating system, based on Xubuntu 10.10, available through the open source Ubuntu project. The system can be installed on a virtual computer, allowing the user to run the system alongside any other operating system. Source codes for all programs are provided under GNU license, which makes it possible to transfer the programs to other systems if so desired. We here demonstrate the package by comparing and analyzing the diversity within the class Negativicutes, represented by 31 genomes including 10 genera. The analyses include 16S rRNA phylogeny, basic DNA and codon statistics, proteome comparisons using BLAST and graphical analyses of DNA structures.

 Paper: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0060120

Address of the bookmark: http://www.cbs.dtu.dk/biotools/CMGtools/