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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/44770?offset=560</link>
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	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40369/phyloxml-xml-for-evolutionary-biology-and-comparative-genomics</guid>
	<pubDate>Sun, 08 Dec 2019 09:41:18 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40369/phyloxml-xml-for-evolutionary-biology-and-comparative-genomics</link>
	<title><![CDATA[phyloXML: XML for evolutionary biology and comparative genomics]]></title>
	<description><![CDATA[<p><a href="http://www.biomedcentral.com/1471-2105/10/356/">phyloXML</a><span>&nbsp;(</span><a href="http://www.phyloxml.org/examples_syntax/phyloxml_syntax_example_1.html">example</a><span>) is an&nbsp;</span><a href="http://en.wikipedia.org/wiki/XML">XML</a><span>&nbsp;language designed to describe phylogenetic trees (or networks) and associated data. PhyloXML provides elements for commonly used features, such as taxonomic information, gene names and identifiers, branch lengths, support values, and gene duplication and speciation events. Using these standardized elements allows interoperability between various applications and databases. Furthermore, both due to extensible nature of XML itself and the provision of &lt;property&gt; elements by phyloXML, extensibility as well as domain specific applications are ensured. The structure of phyloXML is described by&nbsp;</span><a href="http://en.wikipedia.org/wiki/XML_Schema_%28W3C%29">XML Schema Definition (XSD)</a><span>&nbsp;language.</span></p>
<p><a href="http://www.phyloxml.org/archaeopteryx-js/adh.html">http://www.phyloxml.org/archaeopteryx-js/adh.html</a></p><p>Address of the bookmark: <a href="http://www.phyloxml.org/" rel="nofollow">http://www.phyloxml.org/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/41394/ngsymposium-in-computational-biology</guid>
  <pubDate>Mon, 09 Mar 2020 06:00:30 -0500</pubDate>
  <link></link>
  <title><![CDATA[NGSymposium in Computational Biology]]></title>
  <description><![CDATA[
<p>We have a great pleasure to invite you to the NGSymposium in Computational Biology to celebrate the 5th anniversary of the NGSchool Summer Schools. This international conference will make way for exchanging knowledge and experiences between experienced and early-stage researchers as well as bioinformaticians. The meeting will be held on 31.07 - 1.08.2020 in Warsaw. It will be a satellite event to the #NGSchool2020: Statistical Learning in Genomics. It will cover a wide range of topics from basic and applied biomedical sciences: bioinformatics, genomics, transcriptomics, computational biology, Machine Learning.</p>

<p>Registration of active participants will be open from February, 27 12 PM CET to April 17, 23:59 CET. In registration forms you will be asked for providing us with some basic information about yourself. You will also be able to submit your abstract. You can save your registration form after filling it partially and come back later to supply more data e.g. upload an abstract. Your registration will be completed only with the payment of the registration fee reaching our accounts - please make sure to transfer the money in advance!</p>

<p>Registration of passive participants will be open after closing of registration of active participants.</p>

<p>Details an registration: https://ngschool.eu/conference/</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/42793/fully-funded-position-as-phd-research-fellow-in-genomicsbioinformatics</guid>
  <pubDate>Wed, 03 Feb 2021 04:18:57 -0600</pubDate>
  <link></link>
  <title><![CDATA[Fully funded position as PhD Research Fellow in genomics/bioinformatics]]></title>
  <description><![CDATA[
<p>A fully funded position as PhD Research Fellow in genomics/bioinformatics is available at the Section for Genetics and Evolutionary Biology (EVOGENE) at the Department of Biosciences, University of Oslo.</p>

<p>The fellowship will be for a period of 3 years, or for a period of 4 years, with 25 % compulsory work (e.g. teaching responsibilities at the department) contingent on the qualifications of the candidate and the teaching needs of the department.</p>

<p>Starting date no later than October 1, 2021.</p>

<p>More at https://www.jobbnorge.no/en/available-jobs/job/199984/phd-research-fellow-in-genomics-and-bioinformatics</p>
]]></description>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/44400/pevzner-lab</guid>
  <pubDate>Thu, 02 Nov 2023 05:39:26 -0500</pubDate>
  <link></link>
  <title><![CDATA[Pevzner Lab !]]></title>
  <description><![CDATA[
<p>The laboratory works on genome sequencing, immunoproteogenomics, antibiotics sequencing, and comparative genomics - computational technologies that enabled new applications and allowed scientists to attack biological problems that remained beyond the reach of previous techniques.</p>

<p>https://bioalgorithms.ucsd.edu/research4.html</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38233/kubeflow-an-open-community-driven-project-to-make-it-easy-to-deploy-and-manage-an-ml-stack-on-kubernetes</guid>
	<pubDate>Fri, 16 Nov 2018 15:05:14 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38233/kubeflow-an-open-community-driven-project-to-make-it-easy-to-deploy-and-manage-an-ml-stack-on-kubernetes</link>
	<title><![CDATA[Kubeflow: an open, community driven project to make it easy to deploy and manage an ML stack on Kubernetes]]></title>
	<description><![CDATA[<p><span>The Kubeflow project is dedicated to making deployments of machine learning (ML) workflows on Kubernetes simple, portable and scalable. Our goal is not to recreate other services, but to provide a straightforward way to deploy best-of-breed open-source systems for ML to diverse infrastructures. Anywhere you are running Kubernetes, you should be able to run Kubeflow.</span></p><p>Address of the bookmark: <a href="https://www.kubeflow.org/" rel="nofollow">https://www.kubeflow.org/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/45316/from-genes-to-algorithms-the-ai-revolution-in-bioinformatics</guid>
	<pubDate>Wed, 16 Sep 2026 02:23:40 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/45316/from-genes-to-algorithms-the-ai-revolution-in-bioinformatics</link>
	<title><![CDATA[From Genes to Algorithms: The AI Revolution in Bioinformatics]]></title>
	<description><![CDATA[<p>Imagine waking up to a message from your doctor saying your genetic profile has been analyzed and a small change in your DNA has been found that could raise your risk for a certain disease. Instead of being alarmed, you learn that the condition was caught early and your genetic information can help doctors find treatments that might work better for you. Not long ago, this would have seemed like science fiction. But thanks to the rapid progress of artificial intelligence (AI) and bioinformatics, it is becoming more realistic. Bioinformatics brings together biology, computer science, mathematics, and statistics to collect, manage, and analyze biological data. As new technologies produce huge amounts of genomic, transcriptomic, proteomic, and clinical data, traditional methods often cannot keep up. AI is now playing a bigger role in bioinformatics, helping researchers find patterns, make predictions, and understand biological systems in ways that were once out of reach.</p><p>Modern sequencing technologies have turned biology into a data-heavy science. The human genome has about three billion DNA base pairs, and sequencing can produce massive datasets quickly. Bioinformatics helps organize and interpret this information, allowing scientists to compare genomes, find genes, spot genetic differences, study gene expression, and understand diseases at the molecular level. Now, AI is changing how these datasets are analyzed. Machine learning and deep learning can find complex patterns in biological data and make predictions using large datasets. Rather than following only set rules, AI systems can learn from data and help researchers solve tough biological problems.</p><p>A key example of AI in bioinformatics is predicting protein structures. Proteins are vital for many functions in living things, and their three-dimensional shapes are closely tied to what they do. For a long time, figuring out these structures in the lab was slow and difficult. AI-based tools like AlphaFold have shown that deep learning can predict protein structures with impressive accuracy. These advances help speed up biological research and give scientists useful predictions to support their experiments. This shift means bioinformatics is moving from just analyzing biological data to predicting how biology works and designing new solutions.</p><p>AI is also expected to greatly influence drug discovery. Traditionally, developing a new drug is a long and costly process that involves finding biological targets, searching for possible drug molecules, testing how well they work, studying their properties, and running many experiments. AI can help researchers analyze large chemical and biological datasets, predict how molecules might interact with targets, find promising compounds, and estimate properties of drug candidates. Generative AI can even help design new molecules to test in the lab. This does not mean lab experiments will go away, but AI can help researchers focus on the best options and possibly speed up some parts of drug development.</p><p>Personalized medicine is another area where AI-driven bioinformatics could make a big difference. Each person has a unique mix of genetic, molecular, environmental, and lifestyle factors, so people with the same disease might respond differently to the same treatment. Bioinformatics lets researchers study individual biological data, and AI can combine many types of information, like genetic data, gene expression, protein levels, medical images, clinical records, and drug responses. In the future, this could help doctors look beyond just the disease and focus on the specific biology of each patient. This would support more personalized ways to diagnose, assess risk, and choose treatments.</p><p>As AI becomes more common, the job of bioinformaticians will likely change. Instead of spending most of their time on repetitive computer tasks, they may focus more on creating research questions, understanding AI results, checking predictions, and linking computer findings to lab experiments. Future professionals will need to know about molecular biology, genetics, statistics, programming, machine learning, data science, databases, and computational biology. But technical skills alone will not be enough. Being able to ask good scientific questions and carefully judge computer results will be even more important, since AI can make predictions, but scientists must decide if those predictions make sense and can be proven in the lab.</p><p>Even with its great potential, using AI in bioinformatics comes with big challenges. AI systems rely on the quality and variety of the data they are trained on. Biological and clinical datasets can have missing information, technical errors, inconsistent measurements, and may not represent all groups equally. A model that works well on one dataset might not work as well on another group or in a different setting. That is why data quality, proper validation, transparency, reproducibility, and careful model development are crucial for the future of AI in bioinformatics. Researchers also need to think about genetic privacy, data ownership, security, and using personal biological information responsibly. These concerns are especially important when AI predictions are used in healthcare.</p><p>The lab of the future may look very different from today&rsquo;s. Researchers might use AI to review scientific papers, find research questions, analyze large datasets, come up with ideas, and predict which experiments will be most helpful. Automated lab systems could then run these experiments, create new data, and send the results back to computer models. This would create a cycle of making guesses, predicting, experimenting, collecting data, and learning. This approach could speed up scientific discovery by helping researchers explore questions more efficiently. Bioinformatics could become a key link between computer predictions and real lab experiments.</p><p>In the end, the future of bioinformatics with AI will not be about replacing people with machines. It will be about humans and AI working together. Computers can handle huge amounts of biological data and spot patterns that a single person could not. But humans bring scientific understanding, creativity, critical thinking, ethical judgment, and the ability to see the bigger picture. AI might find a pattern in millions of genomes, but scientists need to figure out why it matters. An AI model could suggest a new drug, but researchers must check if it is safe and works well. A computer might find a genetic change, but doctors have to decide what it means for a real patient.</p><p>The future of bioinformatics is closely tied to the future of AI. As biological data grows and AI models get better, bioinformatics may shift from mainly analyzing data to predicting biological processes, designing new molecules, speeding up experiments, and supporting personalized healthcare. For students and researchers, this is an exciting chance to work where biology and technology meet. The most successful people will not just be those who use the latest AI tools, but those who understand biology well enough to ask good questions and judge the answers carefully. The future will not be about AI versus humans, but about people and AI working together to understand life in ways we never could before. The next big discovery may come from this partnership between a biological question, a computer model, a lab experiment, and human curiosity.</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/1973/webinar-wednesday-21-august-2013-at-noon-edt</guid>
	<pubDate>Sun, 11 Aug 2013 19:31:56 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/1973/webinar-wednesday-21-august-2013-at-noon-edt</link>
	<title><![CDATA[Webinar: Wednesday 21 August 2013 at Noon EDT]]></title>
	<description><![CDATA[<p>This webinar will describe the use of combinatorial pooling to reconstruct gene sequences within BACs. Recent work in barley has shown that this level of sequence knowledge is sufficient to support critical end-point objectives such as map-based cloning and marker-assisted breeding.</p><p>http://www.extension.org/pages/67926/upcoming-webinar:-selective-sequencing-through-combinatorial-pooling#.UggsVuHyPqU</p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/10392/research-associate-ra-at-institute-of-advanced-study-in-science-and-technology</guid>
  <pubDate>Mon, 05 May 2014 08:44:24 -0500</pubDate>
  <link></link>
  <title><![CDATA[Research Associate (RA) at INSTITUTE OF ADVANCED STUDY IN SCIENCE AND TECHNOLOGY]]></title>
  <description><![CDATA[
<p>INSTITUTE OF ADVANCED STUDY IN SCIENCE AND TECHNOLOGY<br />(An Autonomous Institute under Department of Science and Technology, Govt. of India)<br />Paschim Boragaon, Garchuk, Guwahati-781035</p>

<p>Appointment Adv.No.2</p>

<p>Applications in plain paper are invited from Indian citizens for one/two position each of Research Associate, Traineeship and Studentship for BIF facility, Division of Life Sciences, IASST.</p>

<p>Applications with complete Bio-data containing contact address, e-mail and phone number, two recent passport size photographs and attested copies of mark sheets, certificates etc., should be sent to the Registrar, IASST, Paschim Boragaon, Garchuk, Guwahati – 781035, Assam, so as to reach on or before 5/05/2014.</p>

<p>A. Research Associate:</p>

<p>Number of vacancies: 1 (One)</p>

<p>Qualifications:</p>

<p>PhD in Bioinformatics or allied disciplines with knowledge of Bioinformatics. The candidates who have submitted PhD thesis may also apply.</p>

<p>In case, candidates having PhD are not found, candidates having MSc in Bioinformatics or allied disciplines with sound knowledge of Bioinformatics will be preferred.</p>

<p>Remuneration: Candidate having PhD will get a consolidated remuneration of Rs. 22,000/- +HRA per month. MSc having NET/GATE/SLET qualified candidate will get a remuneration of Rs. 16,000/= and HRA and candidate with only MSc will get a remuneration of Rs.14,000/- and HRA.</p>

<p>Tenure:</p>

<p>The post is initially for one year and may be extended depending on the performance till the tenure of the project.</p>

<p>B. Traineeship:</p>

<p>Number of vacancies: 2 (Two)</p>

<p>Qualifications:</p>

<p>Candidate with a postgraduate degree in Bioinformatics/Biotechnology/Life sciences from a recognised University</p>

<p>Remuneration: Rs. 5000/month for 6 months</p>

<p>C. Studentship:</p>

<p>Number of vacancies: 2 (Two)</p>

<p>Qualifications:</p>

<p>Candidate pursuing M.Sc in bioinformatics in a recognised University.</p>

<p>Remuneration: Rs. 5000/month for 6 months</p>

<p>Advertisement:</p>

<p>http://iasst.gov.in/pdf/recruitment/advt%20no_2_24042014.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/11195/ncbi-gene-screencast</guid>
	<pubDate>Fri, 30 May 2014 06:21:18 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/11195/ncbi-gene-screencast</link>
	<title><![CDATA[NCBI Gene Screencast]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/WyFIf7YdM8A" frameborder="0" allowfullscreen></iframe>A short walkthrough of the NCBI Gene page]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27961/nearhgt</guid>
	<pubDate>Wed, 22 Jun 2016 05:41:57 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27961/nearhgt</link>
	<title><![CDATA[NearHGT]]></title>
	<description><![CDATA[<p>Horizontal gene transfer (HGT), the transfer of genetic material between organisms, is crucial for genetic innovation and the evolution of genome architecture. Existing HGT detection algorithms rely on a strong phylogenetic signal distinguishing the transferred sequence from ancestral (vertically derived) genes in its recipient genome. Detecting HGT between closely related species or strains is challenging, as the phylogenetic signal is usually weak and the nucleotide composition is normally nearly identical. Nevertheless, there is a great importance in detecting HGT between congeneric species or strains, especially in clinical microbiology, where understanding the emergence of new virulent and drug-resistant strains is crucial, and often time-sensitive.</p>
<p>We developed a novel, self-contained technique named&nbsp;<em>Near HGT</em>, based on the&nbsp;<em>synteny index</em>, to measure the divergence of a gene from its native genomic environment and used it to identify candidate HGT events between closely related strains. The method confirms candidate transferred genes based on the&nbsp;<em>constant relative mutability</em>&nbsp;(CRM). Using CRM, the algorithm assigns a confidence score based on &ldquo;unusual&rdquo; sequence divergence. A gene exhibiting exceptional deviations according to both synteny and mutability criteria, is considered a validated HGT product. We first employed the technique to a set of three&nbsp;<em>E. coli</em>&nbsp;strains and detected several highly probable horizontally acquired genes. We then compared the method to existing HGT detection tools using a larger strain data set.</p>
<p>When combined with additional approaches our new algorithm provides richer picture and brings us closer to the goal of detecting all newly acquired genes in a particular strain.</p>
<p><strong>Availability:</strong><span>&nbsp;The method is publicly available at</span><a href="http://research.haifa.ac.il/~ssagi/software/nearHGT.zip">http://research.haifa.ac.il/~ssagi/software/nearHGT.zip</a></p><p>Address of the bookmark: <a href="http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004408" rel="nofollow">http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1004408</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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