BOL: Related items

Yannick Wurm Lab

Thu, 07 Aug 2014 18:02:37 -0500

Evolutionary genomics of social insects. Extensive theoretical work has explained how and why complex societies evolve. However, only little is known about the genes and molecular mechanisms responsible for social phenotypes. We have been identifying genes and mechanisms involved in the evolution of insect societies using modern genomics tools (Illumina, RNAseq, RADseq...). For example we recently:

1. sequenced and analyzed the genome of the invasive red fire ant Solenopsis invicta (PNAS 2011)

2. discovered that a fundamental social trait in this species (how many queens are accepted in the colony) is determined by variants of a social chromosome (Nature 2013).

3. described the gene expression changes that occur in a virgin queen when she is given the opportunity of replacing her mother (Mol Ecol 2010).

Homepage: http://yannick.poulet.org/

Manolis Kellis Lab

Sun, 31 Jan 2016 20:51:06 -0600

A major focus of our lab is understanding the effects of genetic variation on molecular phenotypes and human disease. We develop methods for integrating diverse functional genomic datasets of transcription, chromatin modifications, regulator binding, and their changes across multiple conditions to interpret genetic associations, identify causal variants, and predict the effects of genetic perturbations.

More at http://compbio.mit.edu

Andi

Jit — Fri, 13 May 2016 05:16:35 -0500

This is the andi program for estimating the evolutionary distance between closely related genomes. These distances can be used to rapidly infer phylogenies for big sets of genomes. Because andi does not compute full alignments, it is so efficient that it scales even up to thousands of bacterial genomes.

This readme covers all necessary instructions for the impatient to get andi up and running. For extensive instructions please consult the manual.

More at https://github.com/evolbioinf/andi/

Address of the bookmark: http://bioinformatics.oxfordjournals.org/content/early/2015/01/13/bioinformatics.btu815.full

PostDoc in Germany @ EvolutionaryTheory

Mon, 03 Aug 2026 06:50:26 -0500

We are seeking a postdoctoral researcher to join the group of Jonathan Henshaw at the University of Freiburg in Germany (https://www.henshaw-lab.com/). We are a primarily theoretical lab working on a broad set of topics in evolutionary biology, with a particular focus on the evolution of animal behaviour. We develop both individual-based simulations and mathematical models (e.g., using evolutionary game theory, adaptive dynamics and quantitative genetics). We put a strong emphasis on a supportive and inclusive working environment. As a postdoc in our lab, you would have considerable freedom to shape the direction of your projects within these broad areas of interest.

More at https://evoldir.net/brian/evoldir/PostDocs//UniFreiburg_Germany.EvolutionaryTheory

The Sheppard Lab

Fri, 09 Aug 2024 02:48:34 -0500

Ineos Oxford Institute of Antimicrobial Research – Department of Biology – University of Oxford

Our research centres on the use of genetics/genomics and phenotypic studies to address complex questions in the ecology, epidemiology and evolution of microbes. Our most recent interest focuses upon comparative genome analysis to describe the core and flexible genome of pathogenic bacteria (Campylobacter, Acinetobacter, Escherichia coli, Helicobacter, Staphylococcus and Streptococcus suis) and how this is related to population genetic structuring, the maintenance of species, and the evolution of host/niche adaptation and virulence.

More at https://sheppardlab.com/research/

Genomic Basis of Evolutionary Innovations (GEvol)

BioStar — Sat, 06 Dec 2025 06:11:00 -0600

The Priority Programme (SPP 2349) funded by German Science Foundation (DFG) started 2022: „Genomic Basis of Evolutionary Innovations (GEvol)“

GEvol is unique as it will use, for the first time, a large taxonomic group to focus on one goal: to characterise the dynamics and mechanisms of genomic innovations underlying novel traits using comparative evolutionary genomics (and related data).
Thus, projects participating in GEvol we will ask fundamental evolutionary questions such as:
1. At what level is evolution repeatable?
2. How does genomic plasticity interfere with phenotypic plasticity during evolution?
3. How do inter- and intra-specific interactions influence genomic architectures?
4. How predictable is phenotypic variation given some knowledge about the dynamics and mechanisms of underlying genome evolution?

Address of the bookmark: https://g-evol.uni-muenster.de/open-positions/

Comparative genomics of gene expression lab

Wed, 09 Sep 2026 03:35:46 -0500

The core expertise of the lab is comparative genomics. We combine evolutionary bioinformatics and molecular biology to understand the mechanism, function and evolution of genes.
We study the processes of gene expression and protein synthesis, and we are particularly interested in the phenomenon of translational recoding (programmed exceptions to the genetic code). For more information, see Research.

More at https://www.mariottigenomicslab.com/

Yeaman Lab

Wed, 16 Sep 2026 04:01:26 -0500

The natural world is a diverse place. To contend with highly variable environments, organisms have evolved a wide range of traits and behaviours as adaptations to their environment. From armour plating in stickleback to trade-offs between growth rate and cold tolerance in lodgepole pine, organisms have found many different genetic solutions to the challenge of existing in their environment. In my lab, we study a range of questions asking how such complex adaptations evolve:
How is the genetic basis of local adaptation shaped by the interplay between natural selection and dispersal?
Does the architecture of genome evolve to facilitate further adaptation?
How can we use genomic technologies and bioinformatics to study adaptation?
How do organisms adapt to rapidly changing environments?

To attempt to answer these questions about the basics of how evolution works, we use a combination of computational biology, analytical theory, comparative genomics.

More at https://yeamanlab.weebly.com

Mulan: Multiple-sequence local alignment and visualization for studying function and evolution

Jit — Fri, 24 Aug 2018 09:50:01 -0500

Mulan: Multiple-sequence local alignment and visualization for studying function and evolution

Mulan (http://mulan.dcode.org/), a novel method and a network server for comparing multiple draft and finished-quality sequences to identify functional elements conserved over evolutionary time. Mulan brings together several novel algorithms: the TBA multi-aligner program for rapid identification of local sequence conservation, and the multiTF program for detecting evolutionarily conserved transcription factor binding sites in multiple alignments. In addition, Mulan supports two-way communication with the GALA database; alignments of multiple species dynamically generated in GALA can be viewed in Mulan, and conserved transcription factor binding sites identified with Mulan/multiTF can be integrated and overlaid with extensive genome annotation data using GALA.

Address of the bookmark: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC540288/

What is the hologenome concept of evolution?

Jit — Wed, 03 Feb 2021 12:23:54 -0600

All multicellular organisms are colonized by microbes, but a gestalt study of the composition of microbiome communities and their influence on the ecology and evolution of their macroscopic hosts has only recently become possible. One approach to thinking about the topic is to view the host–microbiome ecosystem as a “holobiont”.

Address of the bookmark: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198262/