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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/44783?offset=60</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44503/entire-human-genome-sequencing</guid>
	<pubDate>Tue, 02 Apr 2024 01:19:29 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44503/entire-human-genome-sequencing</link>
	<title><![CDATA[Entire Human Genome Sequencing !]]></title>
	<description><![CDATA[<p>Cost-effective whole human genome sequencing has revolutionized the landscape of genetic research and personalized medicine by making comprehensive genetic analysis accessible to a wider population. Through advancements in sequencing technologies, such as next-generation sequencing (NGS), costs have significantly decreased, enabling researchers and healthcare providers to analyze an individual's complete genetic makeup with greater efficiency and affordability. This has profound implications for disease diagnosis, prognosis, and treatment, as it allows for the identification of genetic predispositions and the customization of healthcare interventions based on an individual's unique genetic profile. Moreover, as the cost continues to decline, the potential for population-scale genomic studies and large-scale screening programs becomes increasingly feasible, promising to further enhance our understanding of human genetics and improve healthcare outcomes on a global scale.</p><p>Here are few companies:</p><p>https://mynucleus.com/</p><p>https://myome.com/</p><p>https://nebula.org/whole-genome-sequencing-dna-test/</p>]]></description>
	<dc:creator>LEGE</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/1972/page-lab-at-whitehead-institute-mit</guid>
  <pubDate>Sun, 11 Aug 2013 17:24:05 -0500</pubDate>
  <link></link>
  <title><![CDATA[Page Lab at Whitehead Institute, MIT]]></title>
  <description><![CDATA[
<p>They study the foundations of mammalian reproduction, with particular focus on sex chromosome biology and evolution, the fetal origins of gametes, and infertility.  </p>

<p>PI webpage : http://pagelab.wi.mit.edu/david_page.html</p>

<p>Ted Presentation : http://www.youtube.com/watch?v=nQcgD5DpVlQ</p>

<p>Lab webpage: http://pagelab.wi.mit.edu/index.html</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/12883/breaking-chromosomes-to-study-cancer</guid>
	<pubDate>Fri, 18 Jul 2014 05:42:09 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/12883/breaking-chromosomes-to-study-cancer</link>
	<title><![CDATA[Breaking chromosomes to study cancer !!!]]></title>
	<description><![CDATA[<p>Chromosomes are present in every cell of our body and they contain the information the body needs to develop and function properly. This information is carried in genes that are arranged along the chromosomes. There are usually 46 chromosomes in every cell. These chromosomes come in pairs, one from our mother and one from our father. The chromosomes can be sorted into 23 pairs by looking at them down a microscope.</p><p>Most people who have a balanced translocation have the right amount of chromosome material but it has been rearranged in some way. This may happen if two chromosomes swap pieces (a reciprocal translocation). In other cases two whole chromosomes may become stuck together (a Robertsonian translocation). This page describes what happens when someone has a reciprocal translocation. <br /><br />Reciprocal chromosomal translocations occur following double-strand breaks (DSBs) in DNA when a section of one chromosome is exchanged with that of another, non-homologous chromosome. These exchanges may produce a dysfunctional fusion gene that disrupts cell growth and survival pathways, such as the translocations seen in leukemia and childhood sarcomas. <br /><br />Chromosomal translocations have been well studied in cancer cell lines which are associated with two types of cancer, acute myeloid leukemia and Ewing's sarcoma, but determining how they contribute to cancer development is complicated by additional mutations and altered gene expression profiles in these cultured cells. Now, Juan Carlos Ramirez, head of the Viral Vector Facility at the Fundacion Centro Nacional de Investigaciones Cardiovasculares (CNIC) and his colleagues Raul Torres at CNIC and Sandra Rodriguez-Peralez at the Spanish National Cancer Center (CNIO) in Madrid, Spain have used a new genome editing tool, CRISPR-Cas9, to induce chromosomal translocations for the first time in a human cell line and in primary cells. The study's authors conclude by stating that the use of this technology will allow for the clarification of how and why chromosomal translocation occurs, which without doubt will allow new anti-cancer therapeutic strategies to be tackled.</p><p>Using RNA-Guided Endonuclease (RGEN) technology or CRISPR/Cas9 genome engineering technology, CNIO and CNIC researchers have shown that it is possible to obtain such chromosomal translocations. The CRISPR-Cas9 system is extremely simple to introduce a cut at the desired locus, easier to design, and cheaper than many other systems. Using the CRISPR-Cas9 system, Ramirez and his colleagues reproduced the translocations observed in Ewing&rsquo;s Sarcoma (ES) and Acute Myeloid Leukemia (AML) patient cell lines in HEK293 cells and also generated the ES translocation in human mesenchymal stem cells and the AML translocation in umbilical cord blood cells.</p><p>By focusing on chromosomal translocation without the confounding characteristics of established cell lines, these new cells lines should help answer the fundamental question of what causes a cell to become cancerous. Ramirez and his team now look forward to modeling other chromosome translocations in a variety of cell types.</p><p>Reference:</p><p>http://en.wikipedia.org/wiki/Chromosomal_translocation</p><p>http://www.nature.com/ncomms/2014/140603/ncomms4964/abs/ncomms4964.html<br /><br /></p>]]></description>
	<dc:creator>Jit</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/19648/mit-computational-biology-group</guid>
  <pubDate>Thu, 18 Dec 2014 14:47:01 -0600</pubDate>
  <link></link>
  <title><![CDATA[MIT Computational Biology Group]]></title>
  <description><![CDATA[
<p>My research group consists primarily of computer science graduate students and postdocs with expertise in algorithms, statistical inferences and machine learning, and sharing a passion for understanding fundamental biological problems.</p>

<p>We work in a highly interdisciplinary environment at the interface of Computer Science and Biology. Since its inception, our lab has eagerly engaged in collaborative research partnerships with biological and experimental collaborators, facilitated by our affiliation with the Broad Institute and the Computational and Systems Biology initiative (CSBi) at MIT, our participation in the Epigenome Roadmap, ENCODE, and modENCODE consortia, and by several other ongoing collaborations at MIT, Harvard, and the Harvard Medical School affiliated hospitals.</p>

<p>http://compbio.mit.edu/</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/23149/raphael-lab</guid>
  <pubDate>Sat, 04 Jul 2015 19:05:29 -0500</pubDate>
  <link></link>
  <title><![CDATA[Raphael Lab]]></title>
  <description><![CDATA[
<p>Raphael Lab research is focused on Bioinformatics and Computational Biology.</p>

<p>Current research interests include next-generation DNA sequencing, structural variation, genome rearrangements in cancer and evolution, and network analysis of somatic mutations in cancer. Earlier research included topics in comparative genomics, multiple sequence alignment, and motif finding.</p>

<p>More athttp://compbio.cs.brown.edu/</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26571/pattern-searching-in-a-single-genome</guid>
	<pubDate>Mon, 07 Mar 2016 05:02:51 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26571/pattern-searching-in-a-single-genome</link>
	<title><![CDATA[Pattern Searching in a Single Genome]]></title>
	<description><![CDATA[<p>Pattern searching holds much importance for biologists , for the understanding of DNA ( and its functionality) can be more than a matter of satisfying curiosity , but also give answers to many issuess uchas medical conditions . However,there are a number of ways of searching with in a single chromosome.</p><p>Address of the bookmark: <a href="https://www.stats.ox.ac.uk/__data/assets/pdf_file/0018/5373/LintonFinalReport.pdf" rel="nofollow">https://www.stats.ox.ac.uk/__data/assets/pdf_file/0018/5373/LintonFinalReport.pdf</a></p>]]></description>
	<dc:creator>Aasha</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/38634/eyechrom-visualizing-chromosome-count-data-from-plants</guid>
	<pubDate>Tue, 08 Jan 2019 10:20:54 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/38634/eyechrom-visualizing-chromosome-count-data-from-plants</link>
	<title><![CDATA[EyeChrom: Visualizing Chromosome Count Data From Plants]]></title>
	<description><![CDATA[<p><span>It's goal is to show chromosmal data per genus. Select the genus, and the plot will show the records found for it in the Chromosome Counts Database. note: Report an issue via Gihub: github.com/roszenil/CCDBcurator and github.com/RodrigoRivero/EyeChrom</span></p>
<p>https://bsapubs.onlinelibrary.wiley.com/doi/pdf/10.1002/aps3.1207</p><p>Address of the bookmark: <a href="http://eyechrom.com:3838/EyeChrom/" rel="nofollow">http://eyechrom.com:3838/EyeChrom/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/1897/genetic-test-in-india</guid>
	<pubDate>Sun, 11 Aug 2013 10:54:35 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/1897/genetic-test-in-india</link>
	<title><![CDATA[Genetic Test in India]]></title>
	<description><![CDATA[<p>1.<strong>Xcode Life Sciences Pvt. Ltd.</strong><br /><span>6B, Eldorado,&nbsp;</span><br /><span>112, Nungambakkam High Road,</span><br /><span>Nungambakkam, Chennai 600034</span><br /><span>Tamil Nadu, India&nbsp;</span></p><p>2.<span><strong>Mapmygenome&trade;</strong><br /></span><span>Royal Demeure,HUDA Techno Enclave,<br />Plot No. 12/2, Sector-1 500 081&nbsp;<br />Madhapur,Hyderabad<br />AP, India</span></p><p>3.<strong>&nbsp;DNA Labs India</strong></p><p><strong><a href="http://www.dnalabsindia.com/lab.php">http://www.dnalabsindia.com/lab.php</a></strong></p><p>&nbsp;</p><p>4.<strong>MedGenome Labs Pvt Ltd</strong><br /><span>(Division of SciGenom Labs Pvt Ltd.)</span><br /><span>Plot no: 43A,SDF, 3rd floor</span><br /><span>A Block,CSEZ, Kakanad, Cochin</span><br /><span>Kerala - 682037&nbsp;</span><br /><span>Phone: 0484 - 2413399</span><br /><span>Fax: 0484 - 2413398</span><br /><span>Email:&nbsp;</span><a href="mailto:info@medgenome.com">info@medgenome.com</a></p><p>5.<strong>Narayana Nethralaya</strong></p><p><span>Narayana Hrudayalaya Campus</span><br /><span>Narayana Health City</span><br /><span># 258/A, Bommasandra, Hosur Road,&nbsp;</span><br /><span>Bangalore - 560 099 - INDIA.</span><br /><span>TEL: +91-80-66660655-0658&nbsp;</span><br /><span>FAX: +91-80-66660650&nbsp;</span><br /><span>Mobile: 9902 821128 (Emergency Only)</span><br /><span>e-mail:&nbsp;</span><a href="mailto:info@narayananethralaya.com">info@narayananethralaya.com</a></p><p>6.<strong>BioAxis DNA Research Centre Private Limited</strong><br />13-51,Sri Lakshmi Nagar colony,<br />Besides Big Bazar, Near Kamineni Hospitals<br />GSI Post BandalGuda (L B Nagar) Hydeabad-500068<br />Andhra Pradesh (<strong>India</strong>).<br />Phone :&nbsp;+91-40-24034503/+91-9246338983</p><p>7.<strong>Gene Guiide</strong></p><p>8th Floor, Embassy Towers, 7 Bungalows Rd, Versova, Andheri West, Mumbai-61&nbsp;<br />&nbsp;09167 117799&nbsp;<br />&nbsp;<a href="mailto:info@geneguiide.com" target="_blank">info@geneguiide.com</a>&nbsp;</p><p>See more at: http://www.geneguiide.com</p><p>8.<strong>INDIAN BIOSCIENCES</strong><br />Regd. Office:<br />G-2 (Ground Floor Rear), Kailash Colony, New Delhi - 110048, India.<br />Phone: +91 (0)11 29236088, Email: info@inbdna.com.</p><p>9.<strong>SRL Limited</strong></p><p>GP-26, MARUTI INDUSTRIAL ESTATE,</p><p>UDYOG VIHAR,SECTOR-18,</p><p>GURGAON - 122015</p><p>Tel: 0124-3001243 / 0124-3001209</p><p><strong>SRL Limited</strong><br />VASANT VIHAR, 8, PALAM MARG,<br />NEW DELHI - 110057<br />Tel: 011 - 4229 5333&nbsp;</p><p><strong>Website:</strong>&nbsp;<a href="http://www.srlworld.com/" target="_blank">http://www.srlworld.com</a><br /><strong>National Customer care number:</strong><br />Call Toll Free : 1800-222-660/1800-102-8282&nbsp;<br /><strong>E-mail id:</strong>&nbsp;<a href="mailto:customercare@srl.in">customercare@srl.in</a></p><p>10.<strong>Tata Memorial Centre</strong>,</p><p>Advanced Centre for Treatment, Research and Education in Cancer</p><p>Kharghar, Navi Mumbai - 410 210, INDIA.</p><p>Tel: +91-22-2740 5000</p><p>Fax: +91-22-2740 5085</p><p>E-mail: mail@actrec.gov.in</p><p style="text-align: center;">&nbsp;</p><p style="text-align: center;"><span style="font-size: large;"><a href="mailto:office@actrec.gov.in"></a></span></p><p>&nbsp;</p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/11603/ncbi-webinar</guid>
	<pubDate>Sun, 08 Jun 2014 02:47:01 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/11603/ncbi-webinar</link>
	<title><![CDATA[NCBI Webinar]]></title>
	<description><![CDATA[<p>In less than two weeks, NCBI will offer a webinar entitled "Introducing 3 NCBI Resources to Navigate Testing for Disease Linked Variants: MedGen, GTR and ClinVar". This webinar will delve into the lifecycle of genetic testing and teach attendees how to navigate the NIH Genetic Testing Registry, ClinVar, and MedGen resources. These resources can be used to prepare for clinical cases, access detailed information about orderable genetic tests, interpret test results, and more.</p><p>More at https://attendee.gotowebinar.com/register/8452228815737989634</p>]]></description>
	<dc:creator>Jit</dc:creator>
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/914/welch-lab</guid>
  <pubDate>Mon, 15 Jul 2013 18:21:13 -0500</pubDate>
  <link></link>
  <title><![CDATA[Welch Lab]]></title>
  <description><![CDATA[
<p>They are based in the Department of Genetics at the University of Cambridge. </p>

<p>The research covers diverse areas of evolutionary biology, and molecular evolution in particular. It combines theoretical and empirical approaches, and particularly evolutionary inference from genome sequence data.</p>

<p>Links @ http://www.gen.cam.ac.uk/research/welch/GroupPage/Home.html</p>
]]></description>
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