BOL: Related items

Simka and SimkaMin are comparative metagenomics method dedicated to NGS datasets

Neel — Sat, 06 Jul 2019 13:56:10 -0500

Simka is a de novo comparative metagenomics tool. Simka represents each dataset as a k-mer spectrum and compute several classical ecological distances between them.

Developper: Gaëtan Benoit, PhD, former member of the Genscale team at Inria.

Contact: claire dot lemaitre at inria dot fr

Simka and SimkaMin are comparative metagenomics method dedicated to NGS datasets. https://gatb.inria.fr/software/simka/

Address of the bookmark: https://github.com/GATB/simka

Claus-Peter Stelzer Lab

Mon, 15 Mar 2021 15:24:41 -0500

Interested in various topics at the intersection of ecology and evolution. In my research I use rotifers as model organisms for experimental studies at the individual and population level. Rotifers are ideally suited for this, because populations of thousands can be kept in small containers in the lab, while single individuals can still be handled conveniently.

More at https://www.uibk.ac.at/limno/personnel/stelzer/index.html.en#research

Landry Lab

Thu, 17 Jul 2014 14:33:57 -0500

EVOLUTIONARY AND INTEGRATIVE CELL BIOLOGY

Our research is at the crossroad between cell biology, ecological genomics, systems biology, molecular evolution and population genetics. We study the architecture and evolution of protein and signalling networks.

More at http://landrylab.ibis.ulaval.ca/

Yannick Wurm Lab

Thu, 07 Aug 2014 18:02:37 -0500

Evolutionary genomics of social insects. Extensive theoretical work has explained how and why complex societies evolve. However, only little is known about the genes and molecular mechanisms responsible for social phenotypes. We have been identifying genes and mechanisms involved in the evolution of insect societies using modern genomics tools (Illumina, RNAseq, RADseq...). For example we recently:

1. sequenced and analyzed the genome of the invasive red fire ant Solenopsis invicta (PNAS 2011)

2. discovered that a fundamental social trait in this species (how many queens are accepted in the colony) is determined by variants of a social chromosome (Nature 2013).

3. described the gene expression changes that occur in a virgin queen when she is given the opportunity of replacing her mother (Mol Ecol 2010).

Homepage: http://yannick.poulet.org/

Alignment of closely related whole genomes/scaffolds

Rahul Nayak — Fri, 29 Jan 2016 10:37:27 -0600

With the relative ease and low cost of current generation sequencing technologies has led to a dramatic increase in the number of sequenced genomes for species across the tree of life. This increasing volume of data requires tools that can quickly compare multiple whole-genome sequences, millions of base pairs in length, to aid in the study of populations, pan-genomes, and genome evolution.This bookmaks have been created to report new tools for whole genome alignments.

Please report new whole genome alignment tools under comment sections.

Address of the bookmark: http://www.cs.utoronto.ca/~brudno/721.full.pdf

Lawley Lab

Mon, 09 May 2016 03:29:51 -0500

Lawley Lab are covered with a complex microbial community, known as our microbiota, which plays important roles in our physiology, immunity, metabolism and sustenance. Within the human gastrointestinal tract alone there are over 1,000 bacterial species, which amounts to approximately 10 times more cells than we harbor in our entire body and 200 times more genes than are found within our genome. Lawley Lab are really a 'supraorganism' consisting of our 'human' and 'microbial' selves.

More at http://www.sanger.ac.uk/science/groups/lawley-lab

CHARLES SWANTON LAB

Tue, 11 Dec 2018 08:09:22 -0600

They are using the latest DNA sequencing technology to read the genetic makeup of cancer cells within tumours in ever greater detail, teasing out patterns of evolution (evolutionary rule books), cancer heterogeneity and working out what changes have happened as a tumour evolves. We’re also investigating the processes that cause mutations and accelerate tumour evolution and working out how they might be stopped. And we are running evolutionary clinical trials with immune and targeted therapies to bring the benefits of our work to patients as quickly as possible.

https://www.crick.ac.uk/research/labs/charles-swanton

Postdoc position at Kiel University, Germany

Sat, 28 Aug 2021 01:16:55 -0500

In the Genomic Microbiology Group of Prof. Tal Dagan at the Institute
of Microbiology at Kiel University, Germany, a

Postdoc position (m/w/d)

in the field of computational evolutionary microbiology is available
for an initially limited period of 36 months at the earliest possible
date. The weekly working time corresponds to 100% of full employment
(If the legal requirements under collective bargaining law are met, the
tariff grouping is carried out up to pay scale 13 TV-L. The obligation
to teach amounts to 4 hours.

The Genomic Microbiology Group research interests are focused on
microbial genome evolution with an emphasis on the study of lateral gene
transfer. In our research we use both computational and experimental
approaches (see www.uni-kiel.de/genomik). The position offers the
opportunity to develop an independent research profile within the group
research focus. The successful applicant is expected to be involved
in teaching of bioinformatics and molecular evolution, including the
development of teaching materials (lectures/exercises/short videos).

Your profile:
· Doctoral or PhD degree in Molecular Evolution, Bioinformatics or
related fields.
· Knowledge and experience in programming (e.g., Python) and
biostatistical analysis (e.g., with R or MatLab).
· Any of the following expertise is an advantage: the analysis of
genomic or transcriptomic data, phylogenetic reconstruction,
comparative genomics.
· Good oral and written communication skills in English.
· Ability to teach in German is an advantage (alternatively, an
indication to do so from the 2nd year on).
· Skills and motivation to communicate and interact with other
scientists.

The Christian-Albrechts-University sees itself as a modern and
cosmopolitan employer. We welcome your application regardless of your age,
gender, cultural and social background, religion, ideology, disability
or sexual identity. We promote equality of the sexes.

The Christian-Albrechts-University is committed to the employment of
people with disabilities. Preference will be given to applications from
severely handicapped persons and persons of equal standing, provided
they are suitable.

We expressly welcome applications from people with a migration background.

For enquiries regarding the position, teaching obligations and research
topic please contact Prof. Tal Dagan: tdagan@ifam.uni-kiel.de.

Applications should be submitted by email to Mrs. Haacks
(dhaacks@ifam.uni-kiel.de) as a single PDF and include: (1) a letter of
motivation (max 1 page, Arial 11, line spacing 1.15), (2) CV, (3) PhD
certificate. Please use 'GMG postdoc application - [your name]'
as a subject.

Please, refrain from sending us application photos.

Application deadline: August 31 2021 or until the position is
filled. Interviews will take place during September/October 2021. The
planned starting date for the position is flexible (but in 2021).

Rotifers Lab

Wed, 08 Mar 2023 23:23:14 -0600

For scientists in the MBL’s Gribble Lab, the rotifer (Brachionus manjavacas) is used as a model organism to study evolution, stress responses, the biology of aging, and maternal effects. Rotifers are small, easy to grow in the lab, have a short lifespan, and share many of their genes with humans. That makes them ideal specimens in which to address questions relevant to human health as well as understand basic biological and evolutionary processes. Brachionus rotifers produces eggs that can be completely dried and frozen for decades, then hatch within a day when exposed to water and light.

https://www.mbl.edu/research/research-organisms/rotifer
https://gribblebiolab.org/

SOWDHAMINI Lab

Sun, 15 Sep 2013 09:19:12 -0500

Genome sequencing projects have enormous potential for benefiting human endeavors. However, just as acquiring a language's vocabulary does not enable one to speak it, databases that list the amino acid composition of proteins do not directly tell us much about these proteins' higher-level structure and function. The most productive way to indirectly exploit these databases has been to start with the small number of proteins that are fully-characterised and to assume that other "similar" proteins will have a related structure and function. Proteins with very similar amino acid sequence are "no-brainers", but the real test, which our group largely focuses on, is to detect the "essential" similarity in proteins whose non-critical sections have experienced random rearrangements during evolution. In such cases functionally similar proteins may have less than 25% sequence overlap.

More @ http://www.ncbs.res.in/sowdhamini/groups_sowdhamini.htm