BOL: Related items

Bioinformatics -- Understanding of living systems through information science

Wed, 14 Aug 2013 11:50:17 -0500

Recently, the progress of the Human Genome Project, aiming to decode all human DNA sequences, has highlighted a research field called bioinformatics. In this new field, computers and techniques from information science are not just used as tools to advance life science research; they're expected to have a major impact on how we think about the life sciences. Q. The main feature of bioinformatics is, it utilizes computers to analyze life. One is example is the genome. In all organisms, DNA contains genetic information, and this is called the genome. But the amount of information involved is huge, so recently, it's been read using next-generation sequencers, and analyzed by computers. In bioinformatics research, what we do is utilize those genome information to investigate the principles of life. As an organism evolves, its genome sequence changes through sudden mutations. Additionally, at the genome level, mutations called rearrangements, such as inversions, transpositions, and duplications, occur. The genome comparison system developed by the Sakakibara Lab calculates homologous sequences called anchors, which are conserved between species. If the genome is considered as a long text, then anchors can be thought of as words. Q. We're coming to understand the genomes of various organisms - not just humans, but monkeys, chimpanzees, bacteria, and so on. The first method used to analyze a genome is comparing it with the genomes of other organisms, to see where it's the same and where it's different. In that way, the content of the genome is decoded bit by bit, using computers. By contrast, in our method, we've developed software called Murasaki, which we also use to analyze large genomes, by comparing them with those of other organisms. The Sakakibara Lab uses a next-generation sequencer at Keio University, along with a cluster machine with hundreds of CPUs. In this way, the Lab is analyzing genome mutations that cause cancer, and the genome of the natto production strain Bacillus subtilis. Until now, genome analysis could only be done in national-scale projects. But now, next-generation sequencer development has made genome analysis possible in an ordinary lab. In a world-first achievement, the Sakakibara Lab has decoded the natto bacillus genome, through analysis using Keio's next-generation sequencer. Q. In the future, biology and the life sciences may become almost entirely information science and computer science. And in healthcare, that may enable us, for example, to predict whether individuals are susceptible to cancer, or to certain lifestyle-related diseases, by understanding their personal genome data. So, I think it's amply possible that we can make use of such information effectively, to help people live longer and be free from disease, by thinking about their lifestyle habits. Bioinformatics is only two decades old. In this field, many areas are still unknown. Professor Sakakibara, having been involved since the beginning, will continue tackling new, challenging research projects.

Bioinformatics Project Assistant Level II position at CSIR - Institute of Himalayan Bioresource Technology, Palampur (H.P.)

Thu, 17 May 2018 01:53:17 -0500

Walk-in-Interview is scheduled to be held on the date as mentioned below for selection of Suitable candidates in the following areas under the DBT sponsored project on purely temporary basis for the duration of the project(s) or till completion of projects whichever is earlier:

Project Title:
"Exploration of RBP-RNA interactions to reveal the post-transcriptional regulatory impact, and development of related tools and resource server".

Position: Project Assistant Level II (1 position)
Age : 28 years as on 14.06.2018
Salary : Rs.25,000/- P.M.

as per the funds provisions in the respective projects.

Eligibility Criteria :
Essential Qualifications: M.Sc. in Bioinformatics / Computational Biology or any area of Bioinformatics with 55% marks.

Essential Qualifications: M.Sc. in any area of Life Sciences with 55% marks with Diploma in any area of Bloinformatics.

Essential Qualifications: B.Tech. / M.Tech. in Bioinformatics / Computer Science with 55% marks.

Selection Procedure : Walk In Interview

Date : 14 June, 2018
Time : 9:30 A.M.
Venue : CSIR-IHBT Palampur (H.P.)

For more info refer to following doc:

http://ihbt.res.in/components/com_chronoforms5/chronoforms/uploads/Recruitment/20180516114701_Advt15_2018.pdf

Bioinformatics Infrastructure Facility

Sun, 15 Sep 2013 09:22:25 -0500

The Bioinformatics Infrastructure Facility has started working in the year 2007 at Presidency College, Kolkata. It is one of the premier institutes of India and boasts of a rich heritage and great alumni. The Infrastructure Facility has a dedicated team headed by Sayak Ganguli and ably supported by Priayanka Dhar. The coordinator of the facility is Abhijit Datta of the Post Graduate Department of Botany. The lab mainly focusses on the analysis of the RNA Induced Silencing Complex. Recent highlights include the presentation of a paper at the RNAi World Congress.

More @ http://bioinfo-presiuniv.edu.in/index.php

Applied Statistics for Bioinformatics using R

Neel — Thu, 30 Aug 2018 03:45:39 -0500

The purpose of this book is to give an introduction into statistics in order to solve some problems of bioinformatics. Statistics provides procedures to explore and visualize data as well as to test biological hypotheses. The book intends to be introductory in explaining and programming elementary statistical concepts, thereby bridging the gap between high school levels and the specialized statistical literature

PLOS Computational Biology: Translational Bioinformatics educational resources

Jitendra Narayan — Fri, 16 Aug 2013 12:24:56 -0500

PLOS present collection of Education articles: “Translational Bioinformatics”. This collection is presented as an online “book” which could serve as a reference tool for a graduate level introductory course, marking a step in an exciting new direction for the Education section of the journal.

Blog : http://blogs.plos.org/biologue/2012/12/28/translational-bioinformatics-plos-computational-biology-presents-an-educational-resource-for-an-emerging-field/

Educational Material : http://www.ploscollections.org/article/browseIssue.action?issue=info:doi/10.1371/issue.pcol.v03.i11

Address of the bookmark: http://www.ploscollections.org/article/browseIssue.action?issue=info:doi/10.1371/issue.pcol.v03.i11

BETSY: A new backward-chaining expert system for automated development of pipelines in Bioinformatics

Jit — Mon, 17 Dec 2018 18:46:51 -0600

The BETSY provides a command-line interface and available at https://github.com/jefftc/changlab. A user first searches in the knowledge base for desired output and then BETSY develops an initial workflow to produce that data which is later examined by the user. The user can optimize the parameters, the algorithm to preprocess the data, and normalize it depending on the task.

Currently, BETSY consists of modules required for the microarray and next-generation sequencing data [4] such as expression analysis, classification, peak calling, and visualization.

Address of the bookmark: https://github.com/jefftc/changlab

Translational Bioinformatics: Transforming 300 Billion Points of Data

Tue, 20 Aug 2013 19:03:47 -0500

Translational Bioinformatics: Transforming 300 Billion Points of Data into Diagnostics, Therapeutics, and New Insights into Disease Air date: Wednesday, June 20, 2012, 3:00:00 PM Time displayed is Eastern Time, Washington DC Local Description: There is an urgent need to translate genome-era discoveries into clinical utility, but the difficulties in making bench-to-bedside translations haven't been well described. The nascent field of translational bioinformatics may help. Dr. Butte's lab at Stanford University builds and applies tools that convert more than 300 billion points of molecular, clinical, and epidemiological data (measured by researchers and clinicians over the past decade) into diagnostics, therapeutics, and new insights into disease. Dr. Butte, a bioinformatician and pediatric endocrinologist, will highlight his lab's work on using publicly available molecular measurements to find new uses for drugs, discovering new treatable mechanisms of disease in type 2 diabetes, and evaluating patients presenting with whole genomes sequenced. The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. For more information, visit: The NIH Director's Wednesday Afternoon Lecture Series Author: Atul Butte, M.D., Ph.D., Stanford University Runtime: 01:07:42 Permanent link: http://videocast.nih.gov/launch.asp?17321

Tenure Track position in Bioinformatics at Institute of Neurobiology, UNAM, Querétaro, México

Mon, 10 Jun 2019 00:48:54 -0500

The Institute of Neurobiology UNAM (www.inb.unam.mx) offers a tenure-track position at the level of Assistant Professor (Investigador Asociado C) to develop an original research program in Bioinformatics with applications to neuroscience and to establish multidisciplinary collaboration with other members of the Institute. Applicants are expected to have a doctorate degree, postdoctoral experience related to bioinformatics or genome biology, and a strong track record of peer-reviewed publications. No previous experience in neuroscience is required.

Interested applicants must submit CV and addresses of three references to ataulfo@unam.mx.

Tenure Track position in Genomic Sciences

Laboratorio Internacional de Investigación sobre el Genoma Humano, UNAM Juriquilla, Querétaro, México

The International Laboratory for Human Genome Research, LIIGH-UNAM (www.liigh.unam.mx) offers a tenure-track position at the level of Assistant Professor (Investigador Asociado C) to perform research, teaching and formation of human resources in the area of: “Genomics of Mendelian Diseases”

Applicants are expected to have a doctorate degree, postdoctoral experience related to the above mentioned area and a strong track record of peer-reviewed publications. Interested applicants must submit CV, email addresses of three references, and a three-page project to Dr. Rafael Palacios, Coordinator of LIIGH-UNAM (palacios@liigh.unam.mx) before June 21, 2019 ………………………………………………………………

Tenure Track position in Genomic Sciences

Laboratorio Internacional de Investigación sobre el Genoma Humano, UNAM Juriquilla, Querétaro, México

Applicants are expected to have a doctorate degree, postdoctoral experience related to the above mentioned area and a strong track record of peer-reviewed publications. Interested applicants must submit CV, email addresses of three references, and a three-page statement of research interests to Dr. Rafael Palacios, Coordinator of LIIGH-UNAM (palacios@liigh.unam.mx) before June 21, 2019

Bioinformatician Dreams

Jitendra Narayan — Wed, 21 Aug 2013 10:50:45 -0500

Bioinformatician life is interconnected, they always dream for a powerful server, little more space on server as they are generating lots of data per run, dream to publish results in good impact journals, meetings reminders :) and research analysis off course!!!

Industrial Training in Computer Aided Drug Designing (CADD)

RASA Life Sciences — Wed, 13 Nov 2019 05:00:44 -0600

Learn More about Computer Aided Drug Designing (CADD)!!!

#rasalsi #rasa In our Industrial program you will get Knowledge on RNA Seq, CHIP Seq,

Batch Starts From 18^th November 2019

#hurryup #registernow #enquirenow The primary goal of the industrial training program is to provide students with necessary skills making with employable. RASA LSI trains students with the enhanced skills required for them to excel in jobs in biotechnology, pharmaceuticals, BioIT and related industry sectors. At Rasa you will learn from industry leaders how to apply these skills in life science & have a command over software developing process by using various methodologies. For Registration visit us on: https://www.rasalsi.com/index.php/front-page/industrial-training/