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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/45270?offset=40</link>
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	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/26993/lastz</guid>
	<pubDate>Mon, 18 Apr 2016 04:41:55 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/26993/lastz</link>
	<title><![CDATA[LASTZ]]></title>
	<description><![CDATA[<p>LASTZ is a program for aligning DNA sequences, a pairwise aligner. Originally designed to handle sequences the size of human chromosomes and from different species, it is also useful for sequences produced by NGS sequencing technologies such as Roche 454.</p>
<p>More at http://www.bx.psu.edu/~rsharris/lastz/</p>
<p>Thesis: http://www.bx.psu.edu/~rsharris/rsharris_phd_thesis_2007.pdf</p><p>Address of the bookmark: <a href="http://www.bx.psu.edu/~rsharris/lastz/" rel="nofollow">http://www.bx.psu.edu/~rsharris/lastz/</a></p>]]></description>
	<dc:creator>Abhi</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27094/smash-an-alignment-free-method-to-find-and-visualise-rearrangements-between-pairs-of-dna-sequences</guid>
	<pubDate>Tue, 26 Apr 2016 12:18:49 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27094/smash-an-alignment-free-method-to-find-and-visualise-rearrangements-between-pairs-of-dna-sequences</link>
	<title><![CDATA[Smash: An alignment-free method to find and visualise rearrangements between pairs of DNA sequences]]></title>
	<description><![CDATA[<p><strong>Smash is a completely alignment-free method/tool to find and visualise genomic rearrangements</strong><span>. The detection is based on&nbsp;</span><strong>conditional exclusive compression</strong><span>, namely using a FCM (Markov model), of high context order (typically 20). For visualisation, Smash outputs a&nbsp;</span><strong>SVG image</strong><span>, with an&nbsp;</span><strong>ideogram</strong><span>output architecture, where the patterns are represented with several&nbsp;</span><strong>HSV values</strong><span>&nbsp;(only value varies). The method can perform both in small- and large-scale. Nevertheless is more directed to large-scale since that the main aim of the research is to&nbsp;</span><strong>know where the large-scale [chromosomal by chromosome] of several primates was equal/different, having at a glance a map of the entire genomes</strong><span>.</span></p><p>Address of the bookmark: <a href="http://bioinformatics.ua.pt/software/smash/" rel="nofollow">http://bioinformatics.ua.pt/software/smash/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>

<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/42326/edanchin-lab</guid>
  <pubDate>Thu, 19 Nov 2020 08:00:07 -0600</pubDate>
  <link></link>
  <title><![CDATA[Edanchin Lab]]></title>
  <description><![CDATA[
<p>My main topics of interest are:</p>

<p>The impact of non tree-like evolution such as horizontal gene transfers and hybridization on species biology<br />Evolution and adaptation of animals in the absence of sexual reproduction and the underlying mechanisms<br />Genomic signatures of adaptation to a parasitic life-style</p>

<p>More at https://edanchin.org/</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/44700/professorsenior-lecturer-of-comparative-genomics-university-of-glasgow</guid>
  <pubDate>Fri, 06 Dec 2024 05:16:09 -0600</pubDate>
  <link></link>
  <title><![CDATA[Professor/Senior Lecturer of Comparative Genomics @ University of Glasgow]]></title>
  <description><![CDATA[
<p>University of Glasgow<br />College of Medical, Veterinary and Life Sciences<br />School of Biodiversity, One Health and Veterinary Medicine</p>

<p>Professor/Senior Lecturer of Comparative Genomics<br />Vacancy Ref: 153610<br />Salary: Professor, Grade 10 will be within the Professorial range and<br />subject to negotiation<br />Senior Lecturer, Grade 9, 57,696 - 64,914 per annum</p>

<p>The School of Biodiversity, One Health and Veterinary Medicine has an<br />exciting opportunity to appoint a Professor/Senior Lecturer in Comparative<br />Genomics. You will make a substantial and positive contribution to the<br />strategic direction of the School/College through leading and contributing<br />to research of international standard, high quality teaching at both<br />undergraduate and postgraduate level, securing research funding, and<br />providing academic leadership and management within the School/College.</p>

<p>Applications are invited from candidates of international standing with<br />an appropriate record of academic achievement in comparative genomics<br />and associated omics technologies. We are looking for a candidate who<br />will complement our existing strengths in clinical veterinary medicine,<br />evolutionary biology, and animal physiology, with a demonstrable interest<br />in using domestic mammals among their study systems. We are particularly<br />interested in applications from candidates with a track record of<br />studying health related traits and their underlying genomic basis in<br />companion animals. Traits of specific interest include those related<br />to metabolism, ageing, and disease (e.g. cancer, autoimmune diseases,<br />neuromuscular disorders).</p>

<p>The School of Biodiversity, One Health and Veterinary Medicine is home to<br />researchers studying organismal biology and animal health across a diverse<br />range of systems, approaches and disciplines with existing strengths<br />in infectious disease, physiology, ageing, veterinary epidemiology, and<br />evolution among others. You will be based on the University of Glasgow's<br />Garscube campus, where the majority of veterinary teaching and research<br />infrastructure is located. This includes the Small Animal Hospital (a<br />recent 15M investment) and our Veterinary Diagnostic Services, offering<br />excellent opportunities for collaborative research at the clinical and<br />translational interface, especially with respect to companion animals.</p>

<p>We welcome applications from candidates with a Scottish Credit and<br />Qualification Framework level 12 (PhD) in animal biology, genomics and<br />health or related discipline with an extensive and established reputation<br />in research and significant teaching experience within the subject area.</p>

<p>This post is full time and open ended.</p>

<p>Visit our website for further information on The University of<br />Glasgow's, School of Biodiversity, One Health &amp; Veterinary Medicine,<br />https://www.gla.ac.uk/schools/bohvm/</p>

<p>Informal Enquiries should be directed to Professor Roman Biek,<br />Roman.Biek@glasgow.ac.uk</p>

<p>Apply online at:<br />https://my.corehr.com/pls/uogrecruit/erq_jobspec_version_4.jobspec?p_id=153610</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27333/satsuma-highly-sensitive-whole-genome-synteny-alignments</guid>
	<pubDate>Fri, 13 May 2016 05:25:26 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27333/satsuma-highly-sensitive-whole-genome-synteny-alignments</link>
	<title><![CDATA[SATSUMA : Highly sensitive whole-genome synteny alignments.]]></title>
	<description><![CDATA[<p>Satsuma is a whole-genome synteny alignment program. It takes two genomes, computes alignments, and then keeps only the parts that are orthologous, i.e. following the conserved order and orientation of features, such as protein coding genes, non-coding genes, or neutral sequences. Satsuma does not require any pre-processing, such as repeat masking, since it will automatically detect ambiguous mappings.<br> <br> Satsuma has parallelization built-in and is designed to run on multi-core architectures. The run-time for aligning two bird-size genomes (~1.2 Gb) is around two days on 24 CPUs. <br> <br> You can find the manual <a href="http://satsuma.sourceforge.net/manual.html">here</a>.<br> Download the latest source code from <a href="https://sourceforge.net/projects/satsuma/">here.</a><br> Stable versions can also be downloaded from the <a href="https://www.broadinstitute.org/science/programs/genome-biology/spines">Broad Institute's</a> web site.<br> <br> An incomplete list of questions and answers (yes, these have really been asked by our users! Please feel free to add your own by e-mailing us) is <a href="http://satsuma.sourceforge.net/faq.html">here</a>.<br> <br> If you use Satsuma in your research, please cite:<br> <a href="http://bioinformatics.oxfordjournals.org/content/26/9/1145.long">Grabherr, M. G., Russell, P., Meyer, M., Mauceli, E., Alf&ouml;ldi, J., Di Palma, F., &amp; Lindblad-Toh, K. (2010). Genome-wide synteny through highly sensitive sequence alignment: Satsuma. Bioinformatics, 26(9), 1145-51</a>.</p>
<p><strong>Tutorial at http://evomics.org/learning/genomics/satsuma/</strong></p><p>Address of the bookmark: <a href="http://satsuma.sourceforge.net/" rel="nofollow">http://satsuma.sourceforge.net/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/30102/prism</guid>
	<pubDate>Sat, 10 Dec 2016 15:19:40 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/30102/prism</link>
	<title><![CDATA[PRISM]]></title>
	<description><![CDATA[<p><span>PRISM is a software for split read (reads which span across a structrual variant -- SV ) mapping and SV calling from the mapping result. PRISM is able to detect small insertions and abitrary size deletions, inversions and tandom duplications with the direction of discordant read pairs. PRISM_CTX is a tool for detecting inter-chromosome trans-location events.&nbsp;</span><br><br><span>PRISM and PRISM_CTX were originally designed and written by&nbsp;</span><a href="http://www.cs.toronto.edu/~brudno">Michael Brudno</a><span>&nbsp;and Yue Jiang, The original PRISM publication can be found&nbsp;</span><a href="http://bioinformatics.oxfordjournals.org/content/early/2012/07/31/bioinformatics.bts484.abstract">here</a><span>.&nbsp;</span><br><br><span>The authors may be contacted via e-mail at:&nbsp;</span><em>prism at cs.toronto.edu</em><span>.&nbsp;</span><br><br><span>Additional information is available in the&nbsp;</span><a href="http://compbio.cs.toronto.edu/prism/PRISM_README">PRISM README</a><span>&nbsp;file and&nbsp;</span><a href="http://compbio.cs.toronto.edu/prism/PRISM_CTX_README">PRISM_CTX README</a><span>&nbsp;file.&nbsp;</span></p>
<p>http://compbio.cs.toronto.edu/prism/</p><p>Address of the bookmark: <a href="http://compbio.cs.toronto.edu/prism/" rel="nofollow">http://compbio.cs.toronto.edu/prism/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/45278/the-day-we-began-reading-the-dna-of-the-world</guid>
	<pubDate>Sat, 05 Sep 2026 01:43:21 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/45278/the-day-we-began-reading-the-dna-of-the-world</link>
	<title><![CDATA[The Day We Began Reading the DNA of the World]]></title>
	<description><![CDATA[<div>Picture waking up and knowing that in one lab, a scientist is reading the DNA of a whale. In another, a team is sequencing a rare plant. Meanwhile, researchers in India are decoding the genomes of different human populations.</div><div>&nbsp;</div><div>Many organisms. Many countries. All share one remarkable goal: to understand the genetic story of life.</div><div>DNA is nature's instruction manual, written with just four letters: A, T, C, and G. For years, scientists could only read small sections of this huge book. Now, new sequencing technology lets us read entire genomes like never before.</div><div>&nbsp;</div><div>One of the most ambitious projects is the Earth BioGenome Project (EBP). Its goal is to create reference genomes for about 1.5 million known eukaryotic species. This project links genome research across continents, species, and scientific fields.</div><div>&nbsp;</div><div>But this story goes beyond just animals and plants.</div><div>&nbsp;</div><div><strong>A New Chapter in Human Genomics</strong></div><div>&nbsp;</div><div>Large human genome projects are changing how we understand our own genetic diversity.</div><div>India's GenomeIndia project has sequenced thousands of people from different populations. This work is uncovering genetic variation that global databases have often missed.</div><div>&nbsp;</div><div>Similar population-scale effSimilar large-scale projects are happening worldwide. The All of Us Research Program in the United States, Europe's 1+ Million Genomes initiative, South Korea's national genomic data program, and projects in Saudi Arabia, Australia, and Singapore are all building huge genomic resources.collect DNA.</div><div>&nbsp;</div><div>The real goal is to link genomes with health, disease, and other biological information. This creates a base for more accurate research and, in time, more personalized medicine.</div><div>&nbsp;</div><div><strong>A Race Against Time</strong></div><div>&nbsp;</div><div>There is also an important twist.</div><div>&nbsp;</div><div>We are sequencing Earth's biodiversity even as many species face growing environmental threats.</div><div>A genome alone cannot save a species, but it does keep important information about its biology, evolution, and genetic diversity. This knowledge helps scientists understand risks, guide conservation, and find traits that could help agriculture or medicine.</div><div>&nbsp;</div><div>Projects like the Darwin Tree of Life, which studies species in Britain and Ireland, and the African BioGenome Project, which is growing genomics work across Africa, are key parts of this worldwide effort.</div><div>&nbsp;</div><div>Projects to Watch</div><ol>
<li>Earth BioGenome Project (EBP) - A global effort to sequence and annotate roughly 1.5 million known eukaryotic species and create a comprehensive reference library of Earth's biodiversity.</li>
<li>Vertebrate Genomes Project (VGP) - Focuses on producing high-quality reference genomes for vertebrate species, providing a major foundation for the wider Tree of Life.</li>
<li>Darwin Tree of Life - A UK and Ireland initiative aiming to sequence approximately 70,000 species, creating a detailed genomic map of regional biodiversity.</li>
<li>African BioGenome Project (AfricaBP) - A pan-African initiative focused on sequencing Africa's biodiversity while strengthening genomics and bioinformatics capacity across the continent.</li>
<li>European Reference Genome Atlas (ERGA) - A European effort to generate high-quality reference genomes for Europe's biodiversity and connect national sequencing efforts.</li>
<li>Canada BioGenome Project - Building reference genomes for Canadian biodiversity, supporting conservation, research and the study of ecosystems.</li>
<li>California Conservation Genomics Project - Uses genomics to understand and protect California's biodiversity and help inform conservation decisions.</li>
<li>Bat1K - An ambitious global effort to sequence the genomes of all known bat species, helping scientists study their evolution, longevity, immunity and unique biology.</li>
<li>Bird 10,000 (B10K) - A global project aiming to create genome resources covering the world's bird diversity and reconstruct avian evolutionary history.</li>
<li>Global Invertebrate Genomics Alliance (GIGA) - Builds genomic resources for the enormous and genetically diverse world of invertebrates.</li>
<li>GenomeIndia - India's national human-genome initiative, designed to capture the country's extraordinary population diversity and create a reference resource for Indian genomics.</li>
<li>All of Us Research Program - A US national research program combining genomic information with health and lifestyle data at population scale.</li>
<li>1+ Million Genomes / Genome of Europe - A European effort to enable secure, cross-border use of genomic and health data and develop genome-scale resources involving more than one million people.</li>
<li>Korea National Integrated Bio Big Data Project - South Korea's large-scale national effort combining genomic and health information from a very large population cohort.</li>
<li>Saudi Genome Program - A national genomics initiative focused on genetic diseases, population genomics and precision medicine in Saudi Arabia.</li>
<li>Australian Genomics / Genomics Health Futures Mission - Australia's growing investment in genomic medicine, rare disease research and population-scale health genomics.</li>
</ol><div><strong>The Library of Life</strong></div><div>&nbsp;</div><div>The fuThe future of genomics is not just about sequencing one genome at a time. Now, it is about creating a worldwide network of genomes&mdash;human and non-human, individual and species&mdash;linked by powerful databases and advanced computational tools.ine a library without shelves.</div><div>&nbsp;</div><div>In this library, the books are genomes. The pages are made of DNA. Scientists and machines are the readers. And this library is still being written. Each genome sequenced today adds a new page to the story of life and helps us better understand our place in it.</div>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/19087/dcgor</guid>
	<pubDate>Sat, 08 Nov 2014 14:54:28 -0600</pubDate>
	<link>https://bioinformaticsonline.com/news/view/19087/dcgor</link>
	<title><![CDATA[dcGOR]]></title>
	<description><![CDATA[<p>An R package for analysing ontologies and protein domain annotations has been published in PLoS Computational Biology (http://dx.doi.org/10.1371/journal.pcbi.1003929). The package is distributed as part of CRAN (http://cran.r-project.org/package=dcGOR), and also at GitHub for version control.<br /><br />The dedicated website is available in http://supfam.org/dcGOR, from which several demos are also provided:<br /><br />1. Analysing SCOP domains: http://supfam.org/dcGOR/demo-Fang.html<br /><br />2. Analysing Pfam domains: http://supfam.org/dcGOR/demo-Basu.html<br /><br />3. Analysing InterPro domains: http://supfam.org/dcGOR/demo-Customisation.html<br /><br />&nbsp;</p>]]></description>
	<dc:creator>Martin Jones</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/27090/canu-assembling-large-genomes-with-single-molecule-sequencing-and-locality-sensitive-hashing</guid>
	<pubDate>Tue, 26 Apr 2016 11:38:10 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/27090/canu-assembling-large-genomes-with-single-molecule-sequencing-and-locality-sensitive-hashing</link>
	<title><![CDATA[CANU: Assembling Large Genomes with Single-Molecule Sequencing and Locality Sensitive Hashing.]]></title>
	<description><![CDATA[<p>Canu is a fork of the&nbsp;<a href="http://wgs-assembler.sourceforge.net/wiki/index.php?title=Main_Page" title="Celera Assembler">Celera Assembler</a>&nbsp;designed for high-noise single-molecule sequencing (such as the PacBio RSII or Oxford Nanopore MinION). The software is currently alpha level, feel free to use and report issues encountered.</p>
<p>Canu is a hierachical assembly pipeline which runs in four steps:</p>
<ul>
<li>Detect overlaps in high-noise sequences using&nbsp;<a href="https://github.com/marbl/MHAP" title="MHAP">MHAP</a></li>
<li>Generate corrected sequence consensus</li>
<li>Trim corrected sequences</li>
<li>Assemble trimmed corrected sequences</li>
</ul>
<p>Read the&nbsp;<a href="http://canu.readthedocs.org/" title="docs">documentation</a></p>
<p>New release https://github.com/marbl/canu/releases</p><p>Address of the bookmark: <a href="https://github.com/marbl/canu" rel="nofollow">https://github.com/marbl/canu</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/27344/orffinder-with-smart-blast</guid>
	<pubDate>Tue, 17 May 2016 01:43:15 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/27344/orffinder-with-smart-blast</link>
	<title><![CDATA[ORFfinder with smart BLAST]]></title>
	<description><![CDATA[<p><span>ORF Finder</span></p><p><span><a href="http://www.ncbi.nlm.nih.gov/orffinder">ORFfinder</a><span>&nbsp;is a graphical analysis tool for finding open reading frames (ORFs). We&rsquo;ve been working on a few updates, and we&rsquo;d like to find out what you think about them. Read on to find out what you can do with the new ORFfinder.</span></span></p><p>Smart BLAST (https://ncbiinsights.ncbi.nlm.nih.gov/2015/07/29/smartblast/)</p><p>Select one or a group of ORFs and BLAST several databases at once, and use the newly developed&nbsp;<a href="http://blast.ncbi.nlm.nih.gov/smartblast/">SmartBLAST</a>&nbsp;to verify protein names.&nbsp;Looking for the traditional results from&nbsp;<a href="http://blast.ncbi.nlm.nih.gov/Blast.cgi">BLAST</a>? They&rsquo;re there too.</p>]]></description>
	<dc:creator>Jit</dc:creator>
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