BOL: Related items

Postdoc at UBasel Comparative Single Cell Genomics

Fri, 13 Dec 2024 12:46:19 -0600

A fully funded 4-year Postdoc position is available in the lab of Patrick
Tschopp at the University of Basel, Switzerland, study the molecular and
tissue-scale dynamics during the embryonic formation of the vertebrate
skeleton and compare it across different vertebrate species with distinct
habitats.

We are looking for a highly motivated candidate with a PhD degree in
Bioinformatics or a related field. Candidates are expected to have a
strong background in evolutionary biology and/or comparative functional
genomics. Additional experiences in single cell functional genomics
analyses, statistics and computational data analyses are a plus, as is
an interest in comparative developmental (EvoDevo) questions.

We offer a dynamic and interactive research environment with state-of-the
art research facilities, good research funding and internationally
competitive salaries.

The Tschopp lab (www.evolution.unibas.ch/tschopp/research/)
studies the gene regulatory mechanisms of cell type
specification and evolution in vertebrates. See also our
preprints at https://doi.org/10.1101/2024.03.26.586769 and
https://doi.org/10.1101/2024.11.28.625862 Applications should include
a motivation letter, a CV, a list of publications, a statement about
research interests, as well as the names and contact details of at
least two referees. Applications (in the form of a single .pdf file)
should be sent to Patrick Tschopp (patrick.tschopp@unibas.ch); review
of applications will begin on January 1st 2025, and will continue until
the position is filled.

Postdoc in Comparative Single Cell Genomics at University of Basel

Fri, 06 Dec 2024 23:41:20 -0600

We offer a dynamic and interactive research environment with state-of-the
art research facilities, good research funding and internationally
competitive salaries.

Patrick Tschopp

Liberles Research Group

Wed, 12 Aug 2026 03:39:53 -0500

The Liberles Research Group works in the areas of computational comparative genomics, and molecular evolution. The central theme in the research group is the detection and characterization of the lineage-specific divergence of protein-encoding genes. Much of the work in the group is done in a phylogenetic context. Ultimately, we want to ask the question, “What makes each species unique at the genomic level?” and “what are the processes driving the functional divergence of genomes?”.

More at https://sites.temple.edu/liberles/

When Genes Leave Clues: Reading the Evolutionary Footprints of Life

LEGE — Fri, 11 Sep 2026 13:47:07 -0500

Imagine walking through a forest and finding two sets of footprints that always appear, disappear, and reappear together. You might wonder whether the animals are connected. In genomics, genes leave similar footprints across evolution. When two genes repeatedly occur together—or disappear together—across different species, their shared evolutionary history can provide clues about their function.

This idea, known as phylogenetic profiling, is the foundation of Profylo (https://github.com/MartinSchoenstein/Profylo), an open-source Python toolkit developed for comparing evolutionary profiles and discovering co-evolving genes. Profylo brings together seven profile-comparison methods and four approaches for identifying co-evolving gene clusters, making it easier to explore hidden functional relationships within genomes.

The study demonstrates that even a simple matrix of gene presence and absence can reveal meaningful biological patterns. By following these evolutionary footprints, researchers can generate new hypotheses about unknown genes, pathways, and molecular interactions. In a world where genomes are being sequenced faster than ever, tools like Profylo offer an exciting way to let evolution itself become a guide to understanding gene function.

More at https://link.springer.com/article/10.1007/s00239-025-10280-6

Statistics of current Sequencing and Bioinformatics market

Rahul Agarwal — Wed, 21 Aug 2013 08:29:21 -0500

This survey conducted by Oxford Gene Technology, provider of innovative genetics research and biomarker solutions to advance molecular medicine, has released the results from a recent survey of researchers using next generation sequencing. (Source:http://www.news-medical.net/news/20130821/Oxford-Gene-Technology-releases-next-generation-sequencing-survey-results.aspx )

Address of the bookmark: http://www.ogt.com/assets/0000/3190/NGS_Survey_2013_Infographic_Web.pdf

Bioinformatics market in India

Rahul Agarwal — Fri, 23 Aug 2013 07:08:49 -0500

Key Topics Covered in the Report:

The market size of the Indian Bioinformatics Industry , FY’2007-FY’2013
Market segmentation of India bioinformatics industry by application by sectors, FY’2007-FY’2013
Market Segmentation of India bioinformatics industry by products and services,FY’2007-FY’2013
Market Segmentation of India bioinformatics industry by applications of bioinformatics ,FY’2007-FY’2013
India bioinformatics industry trends and developments
Government regulations and initiatives of India bioinformatics industry
Major bioinformatics research institutes in India
Market Share of leading players in bioinformatics industry in India,FY’2013
Company profiles of major players in India bioinformatics industry
Future outlook and projections on the basis of revenue in India bioinformatics market, FY’2014-FY’2018

(Source: Ken Research)

Address of the bookmark: http://www.kenresearch.com/healthcare/biotechnology/india-bioinformatics-industry-research-report/392-91.html

Molecular Genetics Lecture

Rahul Agarwal — Fri, 27 Sep 2013 04:24:45 -0500

"Robert Sapolsky makes interdisciplinary connections between behavioral biology and molecular genetic influences. He relates protein synthesis and point mutations to microevolutionary change, and discusses conflicting theories of gradualism and punctuated equilibrium and the influence of epigenetics on development theories."

"Robert Sapolsky is an American neuroendocrinologist, professor of biology, neuroscience, and neurosurgery at Stanford University, researcher and author" ----Wikipedia

Address of the bookmark: http://www.youtube.com/watch?v=_dRXA1_e30o

Bioinformatics infrastructure speed up Indian agriculture

Rahul Agarwal — Tue, 07 Jan 2014 12:44:44 -0600

"Realizing the paradigm shift it can bring about, the government is focusing on increased bioinformatics intervention in agri-sciences. Currently under process, the national grid on bioinformatics is expected make much better sense out of huge genomic" -

http://www.biospectrumindia.com/biospecindia/features/203849/supercomputing-indian-agriculture-fast-track-mode/page/1

Science for Life Laboratory (SciLifeLab)-Sweden

Sat, 10 May 2014 06:22:30 -0500

Science for Life Laboratory (SciLifeLab) is a national center for molecular biosciences with focus on health and environmental research. The center combines frontline technical expertise with advanced knowledge of translational medicine and molecular bioscience. SciLifeLab is a national resource and a collaboration between four universities: Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University.

Webpage : https://www.scilifelab.se/about-us/
Opportunity: https://www.scilifelab.se/about-us/career/

Webinar on Streamlining large scale analysis using the Strand NGS Pipeline Manager on 24 Feb 2016

Yeshodari — Fri, 05 Feb 2016 06:43:28 -0600

Live Webinar on Streamlining large scale NGS data analysis using the Strand NGS Pipeline Manager on 24 Feb 2016

Abstract: Strand NGS includes comprehensive workflows for DNA-Seq, RNA-Seq, Small RNA-Seq, ChIP-Seq, MeDIP-Seq, and Methyl-Seq analysis. Each workflow includes a quality assessment and filter section, followed by a workflow-specific analysis section. The pipeline functionality in Strand NGS allows users to execute a sequence of analysis steps with specific parameters - all without any manual intervention. This simplifies the analysis in large scale sequencing projects where every sample needs to be processed identically.

In this webinar we will discuss the pre-packaged pipelines present in Strand NGS. The packaged pipelines have well-chosen default parameters and are suitable for users analyzing data for the first time in the tool. We will also show how advanced users can customize pipelines and share them with other Strand NGS users. Finally, we will show a brief glimpse of an elaborate pipeline that aligns reads, filters poor-quality matches, computes coverage metrics, identifies variants, checks for sample cross-contamination, and emails quality reports - all from within Strand NGS.

Speaker: Dr. Vamsi Veeramachaneni, Vice President - Bioinformatics, Strand Life Sciences

Details: Session 1: 2:30 PM IST, Session 2 : 10:30 PM IST
Register here: http://www.strand-ngs.com/webinar_registration