BOL: Related items

animated 3d cells in the body

Mon, 21 Oct 2013 06:28:18 -0500

cutting edge medical animation of cells

Influenza animation - flu virus mechanism

Thu, 17 Oct 2013 19:43:13 -0500

Animation of the mechanism of an influenza virus and how Crucell's antibodies target the HA1 proteins on the virus and prevent further spread of influenza. Client: Crucell Direction, Design & Animation: Daniel Lim, 2Preform Music & Sound Design: Javier Barrero, Logical Disorder Production Company: David Hager, All Terrain Media

Fertilization (Conception)

Fri, 22 Nov 2013 03:00:35 -0600

View more AMAZING medical animations at http://www.nucleuslibrary.com To download FREE medical animations of pregnancy and birth, visit http://www.prenateperl.com/yt2012 This 3D medical animation shows human fertilization, also known as conception. Fertilization is the epic story of a single sperm facing incredible odds to unite with an egg and form a new human life. The sperm's journey is visualized with rich detail and narrative to convey a fresh understanding of a classic physiological tale. This medical animation portrays the process of human fertilization. Shown at a cellular level magnification, sperm struggle through many obstacles in the female reproductive tract to reach the egg. Visualized at the molecular level, genetic material from the egg and a single sperm combines to form a new human being.

Pharmacogenomics at Mayo Clinic

Mon, 14 Oct 2013 16:21:45 -0500

The right drug, at the right dose, for the right patient. Mayo Clinic uses the latest technologies to understand how drugs will work in individual patients, maximizing drug efficacy and minimizing the potential for side effects.

Retrovirus Replication 3D Animation

Sat, 26 Oct 2013 09:07:25 -0500

The example used is the HIV Lentivirus. This video does a great job describing "complex" retrovirus transcription in a visually appealing way that is sufficient in detail for upper level coursework and possibly graduate coursework. * Modes of action for some anti-viral drugs are also described. NOTE: The viral genome in the form of DNA stays in the cell's chromosome! This is the predominant reason for the persistence of retroviral infections.

Janet Iwasa: How animations can help scientists test a hypothesis

Sun, 10 Aug 2014 15:26:04 -0500

3D animation can bring scientific hypotheses to life. Molecular biologist (and TED Fellow) Janet Iwasa introduces a new open-source animation software designed just for scientists. TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world's leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design -- plus science, business, global issues, the arts and much more. Find closed captions and translated subtitles in many languages at http://www.ted.com/translate Follow TED news on Twitter: http://www.twitter.com/tednews Like TED on Facebook: https://www.facebook.com/TED Subscribe to our channel: http://www.youtube.com/user/TEDtalksDirector

Flow cytometry data analysis

Rahul Agarwal — Sat, 07 Sep 2013 18:09:48 -0500

Flow cytometry is a biophysical laser based instrument used in various purposes like cell counting, cell sorting, biomarker detection, etc.

Single Cell RNAseq data analysis tutorial !!

Robert M Willioms — Mon, 27 Nov 2017 16:24:29 -0600

A major breakthrough (replaced microarrays) in the late 00’s and has been widely used since
Measures the average expression level for each gene across a large population of input cells
Useful for comparative transcriptomics, e.g. samples of the same tissue from different species
Useful for quantifying expression signatures from ensembles, e.g. in disease studies
Insufficient for studying heterogeneous systems, e.g. early development studies, complex tissues (brain)
Does not provide insights into the stochastic nature of gene expression

Following are the useful links:

Single Cell RNAseq data analysis Tutorial

A step-by-step workflow for low-level analysis of single-cell RNA-seq data

A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor

SCell: single-cell RNA-seq analysis software

https://github.com/diazlab/SCell

Beta-Poisson model for single-cell RNA-seq data analyses

https://github.com/nghiavtr/BPSC

Sincera: A Computational Pipeline for Single Cell RNA-Seq Profiling Analysis

https://research.cchmc.org/pbge/sincera.html

SC3 – consensus clustering of single-cell RNA-Seq data

http://biorxiv.org/content/early/2016/09/02/036558

Citrus: A toolkit for single cell sequencing analysis

http://biorxiv.org/content/early/2016/09/14/045070

Single-Cell Resolution of Temporal Gene Expression during Heart Development

http://www.cell.com/developmental-cell/fulltext/S1534-5807(16)30682-7

Scalable latent-factor models applied to single-cell RNA-seq data separate biological drivers from confounding effects

http://biorxiv.org/content/early/2016/11/15/087775

Single cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes

http://genome.cshlp.org/content/early/2016/11/18/gr.212720.116.abstract

SCODE: An efficient regulatory network inference algorithm from single-cell RNA-Seq during differentiation

http://biorxiv.org/content/early/2016/11/21/088856

SCOUP is a probabilistic model to analyze single-cell expression data during differentiation

https://github.com/hmatsu1226/SCOUP

scLVM is a modelling framework for single-cell RNA-seq data

https://github.com/PMBio/scLVM

Selective Locally linear Inference of Cellular Expression Relationships (SLICER) algorithm for inferring cell trajectories

https://github.com/jw156605/SLICER

SinQC: A Method and Tool to Control Single-cell RNA-seq Data Quality

http://www.morgridge.net/SinQC.html

TSCAN: Pseudo-time reconstruction and evaluation in single-cell RNA-seq analysis

https://github.com/zji90/TSCAN

Visualization and cellular hierarchy inference of single-cell data using SPADE

http://www.nature.com/nprot/journal/v11/n7/full/nprot.2016.066.html

OEFinder: Identify ordering effect genes in single cell RNA-seq data

https://github.com/lengning/OEFinder

Cancer Growth Animation

Fri, 20 Sep 2013 06:16:51 -0500

This video demonstrates how cancer growth happens in human body.

Microbiome - Making better use of bacteria

Mon, 14 Oct 2013 16:22:42 -0500

Bacterial cells outnumber human cells 10-to-1 in the average person. Bacterial genes outnumber human genes 100-to-1. Mayo Clinic and the Center for Individualized Medicine are working to understand these diverse populations and design better diagnoses and therapies that can be individualized to the patient. Diseases, such as clostridium difficile, celiac disease, and gluten sensitivities, are being studied. We're also gaining more insight in the many connections between digestive bacteria and autoimmune disorders, like diabetes, rheumatoid arthritis and multiple sclerosis.