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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/4943?offset=190</link>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/914/welch-lab</guid>
  <pubDate>Mon, 15 Jul 2013 18:21:13 -0500</pubDate>
  <link></link>
  <title><![CDATA[Welch Lab]]></title>
  <description><![CDATA[
<p>They are based in the Department of Genetics at the University of Cambridge. </p>

<p>The research covers diverse areas of evolutionary biology, and molecular evolution in particular. It combines theoretical and empirical approaches, and particularly evolutionary inference from genome sequence data.</p>

<p>Links @ http://www.gen.cam.ac.uk/research/welch/GroupPage/Home.html</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/1466/iscb-asia-2013-translational-bioinformatics-conference</guid>
  <pubDate>Thu, 08 Aug 2013 06:31:32 -0500</pubDate>
  <link></link>
  <title><![CDATA[ISCB-Asia 2013 Translational Bioinformatics Conference]]></title>
  <description><![CDATA[
<p>ISCB-Asia 2013<br />Translational Bioinformatics Conference<br />Seoul, Korea<br />October 2 - 4, 2013</p>

<p>For more information visit: http://www.snubi.org/TBC2013/</p>
]]></description>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/1491/2013-nextgen-genomics-bioinformatics-technologies-ngbt-conference-new-delhi-india</guid>
  <pubDate>Thu, 08 Aug 2013 16:21:16 -0500</pubDate>
  <link></link>
  <title><![CDATA[2013 NextGen Genomics &amp; Bioinformatics Technologies (NGBT) Conference, New Delhi, INDIA]]></title>
  <description><![CDATA[
<p>2013 NextGen Genomics &amp; Bioinformatics Technologies (NGBT) Conference</p>

<p>SciGenom Research Foundation (SGRF) and Institute of Genomics and Integrative Biology (IGIB) are pleased to host the Next-Generation Sequencing and Bioinformatics for Genomics &amp; Healthcare conference.</p>

<p>In the ten years since the first human reference genome was completed for US$3 billion the sequencing technologies have radically changed leading to great reduction in sequencing cost. Today a human genome can be sequenced for under US$ 5000 in less than two weeks. It is expected that by the end of 2015 the cost of sequencing a human genome will drop to below thousand dollars. The next generation sequencing technologies over the past five years have enabled a large number of genomic studies that impact human health and disease. Also, this has made possible the growth of microbial, animal and plant genomics studies. While the data production has increased at a rapid pace challenges remain in analyzing and understanding the data. The conference will cover the next generation sequencing (NGS) technologies, bioinformatics for NGS and applications of NGS in many areas including personalized medicine.</p>

<p>For more info : http://www.scigenomconferences.com/2013/default.php</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/file/view/1970/indias-own-first-drug-from-biocon</guid>
	<pubDate>Sun, 11 Aug 2013 16:05:39 -0500</pubDate>
	<link>https://bioinformaticsonline.com/file/view/1970/indias-own-first-drug-from-biocon</link>
	<title><![CDATA[India&#039;s own first drug - from Biocon.]]></title>
	<description><![CDATA[<p><span><span>Psoriasis is immune-mediated disease that effects the skin. the Disease on an average affects about 10-20 million Indians and it attacks the immune system of human beings. In generally occurs, when the immune system mistakes a normal skin cell for a pathogen, and sends out faulty signals that cause overproduction of new skin cells. <a href="http://en.wikipedia.org/wiki/Psoriasis">More at &gt;&gt;</a><br /></span></span></p><p><span><span>Biocon, India's largest publicly-held biotechnology firm, launched its second novel 'lab-to-market' molecule,<strong> Alzumab</strong>, to treat chronic plaque <strong>psoriasis</strong> at a cost 50 per cent lower than the existing one. </span></span></p><p><span><span><span><span>Biocon is bringing Alzumab (a biologic) in the form of a vial after working on it for nearly a decade. The work had initially started in a joint effort with the Center of Molecular Immunology, Havana, but Biocon took control of the programme soon after and also bought out its partner a few years ago. Biocon tell to the media that genotypic played a critical role in functional studies and clinical trial Genomics. </span></span><br /><br />The Biocon drug, at around&nbsp;₹ 7,500 a vial, will cost half as much as the currently available drugs - from Pfizer and J&amp;J - to treat psoriasis, a skin disease that causes rough red areas where the skin comes off in small pieces. A patient is usually prescribed to consume more than 40 vials in a 24-week course.<br /><br /></span></span></p>]]></description>
	<dc:creator>Jitendra Narayan</dc:creator>
	<enclosure url="https://bioinformaticsonline.com/file/download/1970" length="90484" type="image/jpeg" />
</item>

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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/2335/embo-practical-course-bioinformatics-large-scale-data-at-shenzhen-china</guid>
  <pubDate>Wed, 14 Aug 2013 09:50:56 -0500</pubDate>
  <link></link>
  <title><![CDATA[EMBO Practical Course, Bioinformatics, large-scale data, at Shenzhen, China]]></title>
  <description><![CDATA[
<p>This international advanced course will provide training on bioinformatics and statistics methods for genomic research. It will give insight into how biological knowledge can be generated from high-throughput sequencing (DNA-Seq, RNA-seq, ChIP-seq) experiments and will illustrate how to analyze such data. The course covers both the underlying statistical and algorithmic concepts, and the practice of how to automate and code such analyses using the scripting language R.</p>

<p>17 Nov 2013 -22 Nov 2013</p>

<p>More at http://events.embo.org/13-large-scale-data/</p>

<p>Online Registration: https://www.conference-service.com/pc13-47/welcome.cgi</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/2882/phylogenetics</guid>
	<pubDate>Fri, 23 Aug 2013 03:53:43 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/2882/phylogenetics</link>
	<title><![CDATA[Phylogenetics]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/fQwI90bkJl4" frameborder="0" allowfullscreen></iframe>006 - Phylogenetics

Paul Andersen discusses the specifics of phylogenetics.  The evolutionary relationships of organisms are discovered through both morphological and molecular data.  A specific type of phylogenetic tree, the cladogram, is also covered.

Intro Music Atribution
Title: I4dsong_loop_main.wav
Artist: CosmicD
Link to sound: http://www.freesound.org/people/CosmicD/sounds/72556/
Creative Commons Atribution License]]></description>
	
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/4657/giovanni-parmigiani-lab</guid>
  <pubDate>Fri, 20 Sep 2013 13:21:41 -0500</pubDate>
  <link></link>
  <title><![CDATA[Giovanni Parmigiani Lab]]></title>
  <description><![CDATA[
<p>Scientific Interests:</p>

<p>Models and software for predicting who is at risk of carrying genetic variants that confer susceptibility to cancer. Application to breast, ovarian, colorectal, pancreatic and skin cancer.</p>

<p>Statistical methods for the analysis of high throughput genomic data: analysis of cancer genome sequencing projects; integration of genomic information across technologies; cross-study validation of genomics results.</p>

<p>Statistical methods for comparative effectiveness research: comprehensive models for lifetime history of chronic disease outcomes; Bayesian meta-analysis; Bayesian causal inference; decision analysis.</p>

<p>Bayesian modeling and computation: multilevel models; decision theoretic approaches to inference; sequential experimental design and their application to adaptive and multistage studies in clinical and epidemiological research.</p>

<p>http://bcb.dfci.harvard.edu/~gp/index.html</p>

<p>http://scholar.google.com/citations?user=OlpYP3UAAAAJ&amp;hl=en</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4959/evolution-and-cancer</guid>
	<pubDate>Fri, 27 Sep 2013 11:28:49 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4959/evolution-and-cancer</link>
	<title><![CDATA[Evolution and Cancer]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/j3uKOcNwYBw" frameborder="0" allowfullscreen></iframe>Air date:  Wednesday, January 04, 2012, 3:00:00 PM
Time displayed is Eastern Time, Washington DC Local  
 
Category:  Wednesday Afternoon Lectures  
Description:  There is a broad consensus that cancer is the result of somatic cells having serially gained, by a series of mutations, the ability to grow independently, to recruit resources from the circulation and the stroma, to invade local tissues, and to found anatomically distant metastases, ultimately killing the host. From the point of view of the cancer-causing somatic cell population, this is evolution driven by mutation and selection. Genomics has resulted in a parallel consensus that the central functions of all eukaryotes are highly conserved, not only at the level of individual protein functions, but also complex biological pathways and systems. These ideas motivated a comparison between results of molecular genetic studies of experimental evolution in yeast and the molecular genetic phenomena associated with tumorigenesis and tumor progression. We find some very striking similarities, including recurring genomic rearrangements, alterations of the regulation of specific growth-promoting genes, population-genetic features that affect the fitness trajectories of growth rate variants in evolving populations, and physiological and metabolic similarities derived from the conservation of the basic plan of growth and cell multiplication among all eukaryotes. It is hoped that some of the insights from yeast will aid the interpretation of sequence changes found in tumors, especially in the urgent necessity to distinguish 'driver' from 'passenger' mutations." 

David Botstein's fundamental contributions to modern genetics include the development of genetic methods for understanding biological functions and the discovery of the functions of many yeast and bacterial genes. In 1980, Botstein and three colleagues proposed a method for mapping human genes that laid the groundwork for the Human Genome Project. The basic principle of the mapping scheme was to develop, by recombinant DNA techniques, random single-copy DNA probes capable of detecting DNA sequence polymorphisms when hybridized to restriction digests, or specific fragments, of an individual's DNA. The method was used in subsequent years to identify several human disease genes, such as Huntington's and BRCA1. Variations of this method enabled the sequencing phase of the Human Genome Project. 

In the 1990s Botstein, having moved to Stanford University School of Medicine, collaborated with Patrick O. Brown of Stanford in exploiting DNA microarrays to study genome-wide gene expression patterns in yeast and in human cancers. This required developing a new statistical method and graphical interface, widely used today to interpret genomic data. Botstein also has helped to create, with Michael Ashburner and Gerald Rubin, a bioinformatics initiative to unify the representation of gene and gene product attributes across all species, called Gene Ontology. He graduated from Harvard College and earned his doctorate from the University of Michigan. He worked at Massachusetts Institute of Technology from 1967 to 1988; served as vice president for science at Genentech from 1988 to 1990; chaired the Department of Genetics at the Stanford University School of Medicine from 1990 to 2003; and joined the Princeton University faculty in 2003. He has sat on numerous editorial boards and was the founding editor of Molecular Biology of the Cell. Among recent major awards, Bostein won the Peter Gruber Foundation Prize in Genetics in 2003, the Apple Science Innovator Award in 2008, and the Albany Medical Center Prize in 2010. 

The NIH Wednesday Afternoon Lecture Series includes weekly scientific talks by some of the top researchers in the biomedical sciences worldwide. 

For more information, visit: The NIH Director's Wednesday Afternoon Lecture Series  
Author:  Dr. David Botstein, Princeton University  
Runtime:  00:59:58  

Permanent link:  http://videocast.nih.gov/launch.asp?17046]]></description>
	
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<item>
  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/5623/yau-group</guid>
  <pubDate>Tue, 15 Oct 2013 13:05:15 -0500</pubDate>
  <link></link>
  <title><![CDATA[Yau Group]]></title>
  <description><![CDATA[
<p>Yau Group are a new research group based at the Wellcome Trust Centre for Human Genetics and the Department of Statistics at the University of Oxford.</p>

<p>Yau Group develops statistical and computational methods for the analysis of genomic datasets with a particular interest in cancer sequencing applications and the use of Bayesian Statistics.</p>

<p>Yau Group are currently have projects in somatic mutation analysis of heterogeneous cancers, data fusion or integration techniques and single cell genomics.</p>

<p>More @ http://www.well.ox.ac.uk/~cyau/index.html</p>
]]></description>
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<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/6052/university-of-california-irvine-center-for-complex-biological-systems</guid>
	<pubDate>Mon, 04 Nov 2013 17:10:29 -0600</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/6052/university-of-california-irvine-center-for-complex-biological-systems</link>
	<title><![CDATA[University of California, Irvine - Center for Complex Biological Systems]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/chPJ6OdVl4o" frameborder="0" allowfullscreen></iframe>The University of California Irvine's Center for Complex Biological Systems got its start just as there was a revolution in biology. Systems Biology requires that scientists work across many disciplines including engineering, physics and mathematics. The Center specializes in helping form the kinds of teams that will propel biological research into the future. It is also proud to be able to train students in the new interdisciplinary approach.

http://ccbs.uci.edu]]></description>
	
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