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<channel>
	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/5388?offset=90</link>
	<atom:link href="https://bioinformaticsonline.com/related/5388?offset=90" rel="self" type="application/rss+xml" />
	<description><![CDATA[]]></description>
	
	<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/44672/libraries-or-management-tools-for-high-throughput-sequencing-data</guid>
	<pubDate>Fri, 04 Oct 2024 02:45:06 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/44672/libraries-or-management-tools-for-high-throughput-sequencing-data</link>
	<title><![CDATA[Libraries or management tools for high throughput sequencing data]]></title>
	<description><![CDATA[<ul>
<li><a href="http://gatb.inria.fr/"><span>GATB</span></a>&nbsp;Library.&nbsp;The&nbsp;<span>Genome Analysis Toolbox with de-Bruijn graph.&nbsp;</span>A large part of tools developed by the GenScale team are based on this library.<br />These methods enable the analysis of data sets of any size on multi-core desktop computers, including very huge amount of reads data coming from any kind of organisms such as bacteria, plants, animals and even complex samples (<em>e.g.</em>&nbsp;metagenomes). Among them are (the full is available here:&nbsp;<a href="https://gatb.inria.fr/software/">https://gatb.inria.fr/software/</a>):</li>
<li><a href="https://github.com/morispi/LRez"><span>LRez</span></a>: C++ Library and toolkit for the barcode-based management and indexation of linked-read datasets.</li>
</ul><h2>Variant calling and/or genotyping</h2><ul>
<li><a href="https://gatb.inria.fr/software/discosnp/" title="DiscoSNP">DiscoSNP++ and&nbsp;discoSnpRAD</a>: Reference-free small variant discovery (SNPs and indels)</li>
<li><a href="https://gatb.inria.fr/software/mind-the-gap/" title="MindTheGap">MindTheGap</a>: Detection and assembly of large insertion variants</li>
<li><a href="https://gatb.inria.fr/software/takeabreak/" title="TakeABreak">TakeABreak</a>:&nbsp;reference-free inversion discovery tool</li>
<li><a href="https://github.com/llecompte/SVJedi">SVJedi</a>: Structural Variant genotyper with long read data</li>
<li><a href="https://github.com/SandraLouise/SVJedi-graph">SVJedi-graph</a>: Structural Variant genotyper with long read data using a variation graph</li>
</ul><h2>Sequence assembly</h2><ul>
<li><a href="https://github.com/cguyomar/MinYS">MinYS</a>: reference-guided genome assembly in metagenomics data</li>
<li><a href="https://github.com/anne-gcd/MTG-Link">MTG-link</a>: local assembly tool for linked-read data</li>
<li><a href="https://gatb.inria.fr/software/minia/" title="Minia">Minia</a>: De novo short read assembler</li>
<li><a href="https://gatb.inria.fr/de-novo-genome-assembly/">de-novo pipeline</a>:&nbsp;<em>de-novo</em>&nbsp;assembly pipeline (error correction / contigs / scaffolding) for genomes and meta-genomes</li>
<li><a href="https://gatb.inria.fr/software/mapsembler/" title="Mapsembler2">Mapsembler2</a>: Targeted assembly (not maintained)</li>
</ul><h2>Managing k-mers &amp; indexation</h2><ul>
<li><a href="https://github.com/lrobidou/findere">findere</a>:&nbsp;simple strategy for speeding up queries and for reducing false positive calls from any Approximate Membership Query data structure.
<ul>
<li><a href="https://github.com/lrobidou/fimpera">fimpera</a>&nbsp;extends findere adding the abundance information.</li>
</ul>
</li>
<li><a href="https://github.com/tlemane/kmtricks">kmtricks</a>:&nbsp;modular tool suite for counting kmers, and constructing Bloom filters or kmer matrices, for large collections of sequencing data.</li>
<li><a href="https://github.com/tlemane/kmindex">kmindex&nbsp;</a>is a tool for indexing and querying sequencing samples. It is built on top of kmtricks.</li>
<li><a href="https://github.com/pierrepeterlongo/back_to_sequences">back to sequences</a>: Find sequences (reads, unitigs, genes) related to a set of kmers in large datasets, in a matter of seconds.</li>
<li><a href="https://github.com/vicLeva/bqf">Backpack Quotient Filter</a>:&nbsp;k-mer indexing data structure with abundance</li>
<li><a href="http://github.com/GATB/rconnector">short read connector</a>:&nbsp;Detect similar reads from potentially large read set</li>
<li><a href="https://gatb.inria.fr/software/dsk/" title="DSK">DSK</a>:&nbsp;Count K-mer in sequences</li>
</ul><h2>Pangenome graph manipulation</h2><ul>
<li><a href="https://github.com/Tharos-ux/pancat">Pancat</a>: Pangenome Comparison and Analysis Toolkit</li>
<li><a href="https://pypi.org/project/gfagraphs/">GFAGraphs</a>: a Python library to handle pangenome graph files in GFA format.</li>
</ul><h2>Comparative metagenomics with k-mers</h2><ul>
<li><a href="https://github.com/GATB/simka">Simka and SimkaMin</a>:&nbsp;Comparative metagenomics for large-scale datasets</li>
<li><a href="https://team.inria.fr/genscale/high-throughput-sequence-analysis/compreads-metagenomic-data-analysis/">Comparead &amp; Commet</a>:&nbsp;comparison of metagenomic datasets</li>
</ul><h2>Species and bacterial strains identification</h2><ul>
<li><a href="https://github.com/gsiekaniec/ORI">ORI</a>: software using long nanopore reads to identify bacteria present in a sample at the strain level</li>
<li><a href="https://github.com/kevsilva/StrainFLAIR">StrainFLAIR</a>:&nbsp;STRAIN-level proFiLing using vArIation gRaph</li>
</ul><h2>General-purpose sequencing data manipulation</h2><ul>
<li><a href="https://team.inria.fr/genscale/ngs-software/gassst/">GASSST</a>:&nbsp;long read mapper</li>
<li><a href="https://gatb.inria.fr/software/leon/" title="Leon">Leon</a>: short read compressor (now included in GATB-core)</li>
<li><a href="https://gatb.inria.fr/software/bloocoo/" title="Bloocoo">Bloocoo</a>:&nbsp;short read corrector</li>
<li><a href="https://github.com/GATB/bcalm">BCALM</a>:&nbsp;Construct compacted de Bruijn graphs (unitigs)</li>
</ul><h2>&nbsp;Protein Structure</h2><ul>
<li><a href="https://team.inria.fr/genscale/protein-structure/a-purva-contact-map-overlap-solver/">A_Purva</a>:&nbsp;Contact Map Overlap solver</li>
<li><a href="https://team.inria.fr/genscale/protein-structure/md-jeep-distance-geomtry-solver/">MD-Jeep</a>:&nbsp;Distance Geometry solver</li>
<li><a href="https://team.inria.fr/genscale/csa-comparative-structural-alignment/">CSA</a>:&nbsp;Comparative Structural Alignment</li>
</ul><h2>Workflow</h2><ul>
<li><a href="https://team.inria.fr/genscale/workflows/slicee/">SLICEE</a>:&nbsp;parallel execution of bioinformatics workflows</li>
</ul><h3>Comparative Genomics</h3><ul>
<li><a href="https://team.inria.fr/genscale/comparative-genomics/cassis/">CASSIS</a>:&nbsp;detection of rearrangement breakpoints</li>
<li><a href="https://team.inria.fr/genscale/high-throughput-sequence-analysis/plast-intensive-sequence-comparison/">PLAST</a>:&nbsp;intensive bank-to-bank sequence comparison</li>
<li><a href="https://github.com/stephanierobin/DrjBreakpointFinder">DRJBreakpointFinder</a>: detection and precise localization of excision sites in proviral segments</li>
</ul>]]></description>
	<dc:creator>LEGE</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/32131/wgs-celera-assembler-version-83rc2</guid>
	<pubDate>Mon, 10 Apr 2017 04:45:40 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/32131/wgs-celera-assembler-version-83rc2</link>
	<title><![CDATA[WGS Celera Assembler version 8.3rc2]]></title>
	<description><![CDATA[<p>These are release notes for Celera Assembler version 8.3rc2, which was released on May 24, 2015.<br><br>This distribution package provides a stable, tested, documented version of the software.&nbsp; The distribution is usable on most Unix-like platforms, and some platforms have pre-compiled binary distributions ready for installation.<br><br>The source code package includes full source code (revision 4627), Makefiles, and scripts.&nbsp; A subset of the kmer package (http://kmer.sourceforge.net/, version r1994), used by some modules of Celera Assembler, is included.&nbsp; This distribution includes [http://samtools.sourceforge.net/ SAMtools], [http://www.cbcb.umd.edu/software/jellyfish/ Jellyfish 2.0], [https://github.com/pbjd/pbutgcns PBUTGCNS], [https://github.com/PacificBiosciences/pbdagcon PBDAGCON], [https://github.com/PacificBiosciences/BLASR BLASR], and parts of the [https://github.com/PacificBiosciences/FALCON/tree/v0.1.3 Falcon assembler].<br><br>Full documentation can be found online at http://wgs-assembler.sourceforge.net/.</p>
<p>Interesting scripts within it</p>
<p>urbe@urbo214b[bin] ls&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; []<br>-rwxrwxr-x 1 urbe urbe&nbsp; 11K Apr 10 11:41 addCNSToStore<br>-rwxrwxr-x 1 urbe urbe 575K Apr 10 11:41 addReadsToUnitigs<br>-rwxrwxr-x 1 urbe urbe 128K Apr 10 11:41 analyzeBest<br>-rwxrwxr-x 1 urbe urbe 257K Apr 10 11:41 analyzePosMap<br>-rwxrwxr-x 1 urbe urbe 1,5M Apr 10 11:41 analyzeScaffolds<br>-rwxrwxr-x 1 urbe urbe 224K Apr 10 11:41 asmOutputFasta<br>-rwxrwxr-x 1 urbe urbe 448K Apr 10 11:41 asmOutputStatistics<br>-rwxrwxr-x 1 urbe urbe 2,4K Apr 10 11:41 asmToAGP.pl<br>-rwxrwxr-x 1 urbe urbe 7,6M Apr 10 11:41 blasr<br>-rwxrwxr-x 1 urbe urbe 1,6M Apr 10 11:41 bogart<br>-rwxrwxr-x 1 urbe urbe 183K Apr 10 11:41 bogus<br>-rwxrwxr-x 1 urbe urbe 272K Apr 10 11:41 bogusness<br>-rwxrwxr-x 1 urbe urbe 247K Apr 10 11:41 buildPosMap<br>-rwxrwxr-x 1 urbe urbe 213K Apr 10 11:41 buildRefContigs<br>-rwxrwxr-x 1 urbe urbe 990K Apr 10 11:41 buildUnitigs<br>-rwxrwxr-x 1 urbe urbe&nbsp; 18K Apr 10 11:41 ca2ace.pl<br>-rwxrwxr-x 1 urbe urbe&nbsp; 12K Apr 10 11:41 caqc_help.ini<br>-rwxrwxr-x 1 urbe urbe&nbsp; 61K Apr 10 11:41 caqc.pl<br>-rwxrwxr-x 1 urbe urbe&nbsp; 23K Apr 10 11:41 cat-corrects<br>-rwxrwxr-x 1 urbe urbe&nbsp; 24K Apr 10 11:41 cat-erates<br>-rwxrwxr-x 1 urbe urbe 1,9M Apr 10 11:41 cgw<br>-rwxrwxr-x 1 urbe urbe 1,4M Apr 10 11:41 cgwDump<br>-rwxrwxr-x 1 urbe urbe 204K Apr 10 11:41 chimChe<br>-rwxrwxr-x 1 urbe urbe 201K Apr 10 11:40 chimera<br>-rwxrwxr-x 1 urbe urbe 220K Apr 10 11:41 classifyMates<br>-rwxrwxr-x 1 urbe urbe 201K Apr 10 11:41 classifyMatesApply<br>-rwxrwxr-x 1 urbe urbe 215K Apr 10 11:41 classifyMatesPairwise<br>-rwxrwxr-x 1 urbe urbe 366K Apr 10 11:41 computeCoverageStat<br>-rwxrwxr-x 1 urbe urbe 9,8K Apr 10 11:41 convert-fasta-to-v2.pl<br>-rwxrwxr-x 1 urbe urbe&nbsp; 48K Apr 10 11:41 convertOverlap<br>-rwxrwxr-x 1 urbe urbe 119K Apr 10 11:41 convertSamToCA<br>-rwxrwxr-x 1 urbe urbe&nbsp; 20K Apr 10 11:41 convertToPBCNS<br>-rwxrwxr-x 1 urbe urbe 197K Apr 10 11:41 correct-frags<br>-rwxrwxr-x 1 urbe urbe 259K Apr 10 11:41 correct-olaps<br>-rwxrwxr-x 1 urbe urbe 520K Apr 10 11:41 correctPacBio<br>-rwxrwxr-x 1 urbe urbe 540K Apr 10 11:41 ctgcns<br>-rwxrwxr-x 1 urbe urbe 162K Apr 10 11:40 deduplicate<br>-rwxrwxr-x 1 urbe urbe&nbsp; 37K Apr 10 11:41 demotePosMap<br>-rwxrwxr-x 1 urbe urbe 1,5M Apr 10 11:41 dumpCloneMiddles<br>-rwxrwxr-x 1 urbe urbe 124K Apr 10 11:41 dumpPBRLayoutStore<br>-rwxrwxr-x 1 urbe urbe 1,3M Apr 10 11:41 dumpSingletons<br>-rwxrwxr-x 1 urbe urbe 171K Apr 10 11:41 erate-estimate<br>-rwxrwxr-x 1 urbe urbe 221K Apr 10 11:40 estimate-mer-threshold<br>-rwxrwxr-x 1 urbe urbe 1,5M Apr 10 11:41 extendClearRanges<br>-rwxrwxr-x 1 urbe urbe 1,3M Apr 10 11:41 extendClearRangesPartition<br>-rwxrwxr-x 1 urbe urbe 205K Apr 10 11:40 extractmessages<br>-rwxrwxr-x 1 urbe urbe 7,2M Apr 10 11:41 falcon_sense<br>-rwxrwxr-x 1 urbe urbe 9,8K Apr 10 11:41 fastaToCA<br>-rwxrwxr-x 1 urbe urbe 124K Apr 10 11:40 fastqAnalyze<br>-rwxrwxr-x 1 urbe urbe 137K Apr 10 11:40 fastqSample<br>-rwxrwxr-x 1 urbe urbe&nbsp; 62K Apr 10 11:40 fastqSimulate<br>-rwxrwxr-x 1 urbe urbe 121K Apr 10 11:40 fastqSimulate-sort<br>-rwxrwxr-x 1 urbe urbe 246K Apr 10 11:40 fastqToCA<br>-rwxrwxr-x 1 urbe urbe 140K Apr 10 11:41 filterOverlap<br>-rwxrwxr-x 1 urbe urbe 341K Apr 10 11:40 finalTrim<br>-rwxrwxr-x 1 urbe urbe 228K Apr 10 11:41 fixUnitigs<br>-rwxrwxr-x 1 urbe urbe 147K Apr 10 11:40 fragmentDepth<br>-rwxrwxr-x 1 urbe urbe&nbsp; 29K Apr 10 11:41 fragsInVars<br>-rwxrwxr-x 1 urbe urbe 545K Apr 10 11:41 frgs2clones<br>-rwxrwxr-x 1 urbe urbe 398K Apr 10 11:40 gatekeeper<br>-rwxrwxr-x 1 urbe urbe 139K Apr 10 11:40 gatekeeperbench<br>-rwxrwxr-x 1 urbe urbe 167K Apr 10 11:40 gkpStoreCreate<br>-rwxrwxr-x 1 urbe urbe 147K Apr 10 11:40 gkpStoreDumpFASTQ<br>-rwxrwxr-x 1 urbe urbe 184K Apr 10 11:41 greedyFragmentTiling<br>-rwxrwxr-x 1 urbe urbe 1,6K Apr 10 11:41 greedy_layout_to_IUM<br>-rwxrwxr-x 1 urbe urbe 142K Apr 10 11:40 initialTrim<br>-rwxrwxr-x 1 urbe urbe 967K Apr 10 11:41 jellyfish<br>-rwxrwxr-x 1 urbe urbe 219K Apr 10 11:41 markRepeatUnique<br>-rwxrwxr-x 1 urbe urbe 273K Apr 10 11:40 markUniqueUnique<br>-rwxrwxr-x 1 urbe urbe 114K Apr 10 11:40 mercy<br>-rwxrwxr-x 1 urbe urbe 3,8K Apr 10 11:41 mergeqc.pl<br>-rwxrwxr-x 1 urbe urbe 422K Apr 10 11:40 merTrim<br>-rwxrwxr-x 1 urbe urbe 125K Apr 10 11:40 merTrimApply<br>-rwxrwxr-x 1 urbe urbe 376K Apr 10 11:40 meryl<br>-rwxrwxr-x 1 urbe urbe 176K Apr 10 11:41 metagenomics_ovl_analyses<br>-rwxrwxr-x 1 urbe urbe 297K Apr 10 11:41 olap-from-seeds<br>-rwxrwxr-x 1 urbe urbe 275K Apr 10 11:41 outputLayout<br>-rwxrwxr-x 1 urbe urbe 229K Apr 10 11:41 overlapInCore<br>-rwxrwxr-x 1 urbe urbe 144K Apr 10 11:40 overlap_partition<br>-rwxrwxr-x 1 urbe urbe 179K Apr 10 11:41 overlapStats<br>-rwxrwxr-x 1 urbe urbe 179K Apr 10 11:41 overlapStore<br>-rwxrwxr-x 1 urbe urbe 153K Apr 10 11:41 overlapStoreBucketizer<br>-rwxrwxr-x 1 urbe urbe 175K Apr 10 11:41 overlapStoreBuild<br>-rwxrwxr-x 1 urbe urbe&nbsp; 33K Apr 10 11:41 overlapStoreIndexer<br>-rwxrwxr-x 1 urbe urbe&nbsp; 48K Apr 10 11:41 overlapStoreSorter<br>-rwxrwxr-x 1 urbe urbe 604K Apr 10 11:40 overmerry<br>lrwxrwxrwx 1 urbe urbe&nbsp;&nbsp;&nbsp; 4 Apr 10 11:41 pacBioToCA -&gt; PBcR<br>-rwxrwxr-x 1 urbe urbe 131K Apr 10 11:41 PBcR<br>-rwxrwxr-x 1 urbe urbe 2,9M Apr 10 11:41 pbdagcon<br>-rwxrwxr-x 1 urbe urbe 1,9M Apr 10 11:41 pbutgcns<br>-rwxrwxr-x 1 urbe urbe 201K Apr 10 11:40 remove_fragment<br>-rwxrwxr-x 1 urbe urbe 153K Apr 10 11:40 removeMateOverlap<br>-rwxrwxr-x 1 urbe urbe 2,5K Apr 10 11:41 replaceUIDwithName-fastq<br>-rwxrwxr-x 1 urbe urbe 1,2K Apr 10 11:41 replaceUIDwithName-posmap<br>-rwxrwxr-x 1 urbe urbe 1,3M Apr 10 11:41 resolveSurrogates<br>-rwxrwxr-x 1 urbe urbe 139K Apr 10 11:41 rewriteCache<br>-rwxrwxr-x 1 urbe urbe 232K Apr 10 11:41 runCA<br>-rwxrwxr-x 1 urbe urbe&nbsp; 88K Apr 10 11:41 runCA-dedupe<br>-rwxrwxr-x 1 urbe urbe&nbsp; 14K Apr 10 11:41 runCA-overlapStoreBuild<br>-rwxrwxr-x 1 urbe urbe 3,6K Apr 10 11:41 run_greedy.csh<br>-rwxrwxr-x 1 urbe urbe 297K Apr 10 11:40 sffToCA<br>-rwxrwxr-x 1 urbe urbe&nbsp; 13K Apr 10 11:40 show-corrects<br>-rwxrwxr-x 1 urbe urbe 557K Apr 10 11:41 splitUnitigs<br>-rwxrwxr-x 1 urbe urbe 1,4M Apr 10 11:41 terminator<br>drwxrwxr-x 2 urbe urbe 4,0K Apr 10 11:41 TIGR<br>-rwxrwxr-x 1 urbe urbe 526K Apr 10 11:41 tigStore<br>-rwxrwxr-x 1 urbe urbe&nbsp; 35K Apr 10 11:41 tracearchiveToCA<br>-rwxrwxr-x 1 urbe urbe&nbsp; 35K Apr 10 11:41 tracedb-to-frg.pl<br>-rwxrwxr-x 1 urbe urbe&nbsp; 44K Apr 10 11:41 trimFastqByQVWindow<br>-rwxrwxr-x 1 urbe urbe&nbsp; 18K Apr 10 11:40 uidclient<br>-rwxrwxr-x 1 urbe urbe 589K Apr 10 11:41 unitigger<br>-rwxrwxr-x 1 urbe urbe&nbsp; 42K Apr 10 11:40 upgrade-v8-to-v9<br>-rwxrwxr-x 1 urbe urbe&nbsp; 42K Apr 10 11:40 upgrade-v9-to-v10<br>-rwxrwxr-x 1 urbe urbe&nbsp; 854 Apr 10 11:41 utg2fasta<br>-rwxrwxr-x 1 urbe urbe 731K Apr 10 11:41 utgcns<br>-rwxrwxr-x 1 urbe urbe 561K Apr 10 11:41 utgcnsfix<br><br><br></p><p>Address of the bookmark: <a href="http://wgs-assembler.sourceforge.net/wiki/index.php/Main_Page" rel="nofollow">http://wgs-assembler.sourceforge.net/wiki/index.php/Main_Page</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/35249/gpopsim-a-simulation-tool-for-whole-genome-genetic-data</guid>
	<pubDate>Wed, 17 Jan 2018 03:47:46 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/35249/gpopsim-a-simulation-tool-for-whole-genome-genetic-data</link>
	<title><![CDATA[GPOPSIM: a simulation tool for whole-genome genetic data]]></title>
	<description><![CDATA[<p><span>GPOPSIM is a simulation tool for pedigree, phenotypes, and genomic data, with a variety of population and genome structures and trait genetic architectures. It provides flexible parameter settings for a wide discipline of users, especially can simulate multiple genetically correlated traits with desired genetic parameters and underlying genetic architectures.</span></p><p>Address of the bookmark: <a href="https://github.com/SCAU-AnimalGenetics/GPOPSIM" rel="nofollow">https://github.com/SCAU-AnimalGenetics/GPOPSIM</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/40115/naegleria-fowleri-brain-eating-amoebae</guid>
	<pubDate>Thu, 10 Oct 2019 22:12:03 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/40115/naegleria-fowleri-brain-eating-amoebae</link>
	<title><![CDATA[Naegleria fowleri: brain eating amoebae]]></title>
	<description><![CDATA[<div><em>Naegleria fowleri</em>&nbsp;is a free living, universally distributed amoeba, which is mostly found in natural, stagnant, warm water bodies such as ponds, lakes, etc. It is also reported to be present even in indoor water bodies, such as swimming pools within a temperature range of 40&ndash;45&deg;C.&nbsp;</div><div>&nbsp;</div><div><img src="https://d.newsweek.com/en/full/351971/naegleria-fowleri.jpg" alt="image" width="720" height="634" style="border: 0px; border: 0px;">&nbsp;</div><div><em style="font-size: 12.8px;">N. fowleri</em>&nbsp;infects the central nervous system of human body by entering through the nose during swimming and outdoor baths in natural stagnant water bodies, leading to meningoencephalitis. It is a condition of inflammation of cerebral tissues and membranes of the brain and is mostly fatal in nature. Casualties due to N. fowleri infections are reported all across the globe including a few in India but only seven survivors in the entire world have been reported till 2015.</div><div>&nbsp;</div><div>You can find two genome assembly at&nbsp;</div><div><a href="https://www.ncbi.nlm.nih.gov/assembly/?term=naegleria%20fowleri">https://www.ncbi.nlm.nih.gov/assembly/?term=naegleria%20fowleri</a></div><div>&nbsp;</div><div>More at&nbsp;<a href="https://www.ncbi.nlm.nih.gov/search/all/?term=naegleria+fowleri">https://www.ncbi.nlm.nih.gov/search/all/?term=naegleria+fowleri</a></div>]]></description>
	<dc:creator>Neel</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41869/hs3d-homo-sapiens-splice-sites-dataset</guid>
	<pubDate>Fri, 12 Jun 2020 12:33:17 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41869/hs3d-homo-sapiens-splice-sites-dataset</link>
	<title><![CDATA[HS3D: Homo Sapiens Splice Sites Dataset]]></title>
	<description><![CDATA[<p>HS3D (Homo Sapiens Splice Sites Dataset) is a data set of Homo Sapiens Exon, Intron and Splice regions extracted from GenBank Rel.123. The aim of this data set is to give standardized material to train and to assess the prediction accuracy of computational approaches for gene identification and characterization. From the complete GenBank (Primate Sequences Division) Rel.123 (162,557 entries), entries of Human Nuclear DNA including Complete CDS and more than one Exon have been selected, and 4523 exons and 3802 introns have been extracted from these entries. Details about extracted exons and introns are reported (Locus, number, Start and End position in the entry, sequence, length, G+C content, presence of not AGCT data (nucleotide scan check)). Statistics are also reported (overall nucleotides, average G+C content, nucleotide scan check results, number of not GT starting / AG ending introns, minimum /&nbsp; &nbsp;maximum / average length, length standard deviation) . 3799+3799 donor and acceptor sites, as windows of 140 nucleotides around&nbsp; each splice site have been extracted. After discarding sequences not including canonical GT&ndash;AG junctions (65+74),&nbsp; including insufficient data (not enough material for a 140 nucleotide window) (686+589),&nbsp; including not AGCT bases (29+30), and redundant (218+226) there are 2796+ 2880 windows.&nbsp;</p>
<p>1. P.Pollastro, S.Rampone (2002). HS3D, a Dataset of Homo Sapiens Splice Regions, and its Extraction Procedure from a Major Public Database , International Journal of Modern Physics C, 13(8), 1105-1117. (please cite this paper)</p>
<p>2. P.Pollastro, S.Rampone (2003). HS3D: Homo Sapiens Splice Site Data Set , Nucleic Acids Research, 2003 Annual Database Issue.</p><p>Address of the bookmark: <a href="http://www.sci.unisannio.it/docenti/rampone/" rel="nofollow">http://www.sci.unisannio.it/docenti/rampone/</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
</item>
<item>
	<guid isPermaLink="true">https://bioinformaticsonline.com/blog/view/44791/hibc-human-intestinal-bacteria-collection</guid>
	<pubDate>Wed, 07 May 2025 05:49:19 -0500</pubDate>
	<link>https://bioinformaticsonline.com/blog/view/44791/hibc-human-intestinal-bacteria-collection</link>
	<title><![CDATA[HiBC: Human Intestinal Bacteria Collection]]></title>
	<description><![CDATA[<p>The human gut is home to trillions of microorganisms, forming one of the most complex and dynamic microbial ecosystems known to science. The <strong style="font-size: 12.8px;">Human Intestinal Bacteria Collection (HiBC)</strong><span style="font-size: 12.8px; font-weight: normal;"> is a pioneering initiative aimed at cataloging, preserving, and studying the diverse bacterial species that inhabit the human gastrointestinal tract. This curated collection serves as a critical resource for researchers working on microbiome-related health, disease, and therapeutics.</span></p><h2>What is HiBC?</h2><p>The Human Intestinal Bacteria Collection (HiBC) is a comprehensive, high-quality reference repository of bacterial isolates derived from human fecal samples. It focuses on anaerobic and facultative anaerobic bacteria that play pivotal roles in digestion, immune modulation, vitamin synthesis, and pathogen resistance. The collection includes both culturable strains and genomic data from unculturable taxa, bridging the gap between culture-dependent and -independent microbiome studies.</p><h2>Why is HiBC Important?</h2><ol>
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<p><strong>Understanding Microbiome-Host Interactions</strong><br /> HiBC enables deeper insight into the functions of specific bacterial taxa in the gut. With well-characterized isolates, researchers can conduct mechanistic studies to explore how certain bacteria influence metabolism, inflammation, or mental health.</p>
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<p><strong>Precision Probiotics and Therapeutics</strong><br /> By providing access to native human gut microbes, HiBC supports the development of next-generation probiotics, live biotherapeutic products (LBPs), and fecal microbiota transplantation (FMT) alternatives.</p>
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<p><strong>Standardization and Reproducibility</strong><br /> With standardized cultivation and genomic protocols, HiBC ensures consistency across microbiome research studies, improving reproducibility and comparability of findings.</p>
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<p><strong>Antimicrobial Resistance (AMR) Surveillance</strong><br /> HiBC includes metadata on antibiotic resistance genes (ARGs), helping track the spread of AMR in commensal gut bacteria and understanding its implications for human health.</p>
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</ol><h2>Key Features of HiBC</h2><ul>
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<p><strong>Culturable Bacteria Repository:</strong> A living collection of anaerobic and facultative strains isolated from healthy and diseased individuals worldwide.</p>
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<p><strong>Metadata-rich Entries:</strong> Each isolate is annotated with host details (age, health status, diet), geographical origin, phenotypic traits, and antibiotic susceptibility profiles.</p>
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<p><strong>Whole Genome Sequencing (WGS):</strong> High-quality genome assemblies for most strains to support functional and comparative genomics.</p>
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<p><strong>Interactive Database Access:</strong> User-friendly search and filtering options for strain selection based on taxonomy, function, or clinical relevance.</p>
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<p><strong>Cross-linking with Other Databases:</strong> Integration with NCBI, GOLD, and Human Microbiome Project (HMP) data for broader context and validation.</p>
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</ul><h2>Applications of HiBC</h2><ul>
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<p>Microbiome-based diagnostics and biomarker discovery</p>
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<p>Host-microbe interaction studies in gnotobiotic mouse models</p>
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<p>Gut microbiome modulation through diet, drugs, or engineered bacteria</p>
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<p>Longitudinal studies of gut flora across age, geography, and lifestyle</p>
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<p>Environmental and evolutionary microbiology of human-associated bacteria</p>
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</ul><h2>Accessing HiBC</h2><p>Researchers and interested parties can explore the HiBC database through its official website: <a href="https://www.hibc.rwth-aachen.de/" target="_new">https://www.hibc.rwth-aachen.de/</a>. The platform offers comprehensive information on bacterial isolates, including taxonomy, cultivation conditions, and genomic data, facilitating advanced research in human gut microbiome studies.</p><h2>Final Thoughts</h2><p>The <strong>HiBC</strong> is a cornerstone resource in the rapidly evolving field of microbiome research. As science moves toward personalized medicine and microbial therapeutics, having a reliable and diverse collection of human gut bacteria is not just useful &mdash; it's essential. Whether you're a microbiologist, clinician, computational biologist, or biotechnologist, HiBC offers tools to accelerate discovery and innovation in gut microbiome science.</p>]]></description>
	<dc:creator>BioStar</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/45309/ley-lab</guid>
  <pubDate>Fri, 11 Sep 2026 13:21:10 -0500</pubDate>
  <link></link>
  <title><![CDATA[Ley Lab !]]></title>
  <description><![CDATA[
<p>Research Program aims to elucidate how gut microbial species relate to genotypic differences between human individuals, to identify bacterial and archaeal species that share an evolutionary history with humans, and to determine the molecular basis of long-term host-microbial relationships. We approach these aims through a combination of population-level observations and laboratory-based molecular-level investigations. We link inter-microbial and microbial-host interactions at the molecular scale to patterns at population and evolutionary scales. </p>

<p>More at https://leylab.com/</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41158/carefully-opt-for-human-reference-genome</guid>
	<pubDate>Tue, 18 Feb 2020 07:43:32 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41158/carefully-opt-for-human-reference-genome</link>
	<title><![CDATA[Carefully opt for human reference genome]]></title>
	<description><![CDATA[<p><a href="http://lh3.github.io/2017/11/13/which-human-reference-genome-to-use" target="_blank">Heng Li posted several issues with the human reference genomes given in these resources</a> and suggests the following compressed FASTA file to be used as hg38/GRCh38 human reference genome.</p>
<p>if you map reads to GRCh38 or hg38, use the following:</p>
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<pre><code>ftp://ftp.ncbi.nlm.nih.gov/genomes/all/GCA/000/001/405/GCA_000001405.15_GRCh38/seqs_for_alignment_pipelines.ucsc_ids/GCA_000001405.15_GRCh38_no_alt_analysis_set.fna.gz
</code></pre>
</div>
</div>
<p>There are several other versions of GRCh37/GRCh38. What&rsquo;s wrong with them? Here are a collection of potential issues:</p>
<p>More at http://lh3.github.io/2017/11/13/which-human-reference-genome-to-use</p><p>Address of the bookmark: <a href="http://lh3.github.io/2017/11/13/which-human-reference-genome-to-use" rel="nofollow">http://lh3.github.io/2017/11/13/which-human-reference-genome-to-use</a></p>]]></description>
	<dc:creator>biogeek</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/41144/seqmule-automated-human-exomegenome-variants-detection</guid>
	<pubDate>Tue, 18 Feb 2020 03:22:54 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/41144/seqmule-automated-human-exomegenome-variants-detection</link>
	<title><![CDATA[SeqMule: Automated human exome/genome variants detection]]></title>
	<description><![CDATA[<p>SeqMule takes single-end or paird-end FASTQ or BAM files, generates a script consisting of more than 10 popular alignment, analysis tools and runs the script line by line. Users can change the pipeline or fine-tune the parameters by modifying its configuration file.</p><p>Address of the bookmark: <a href="https://doc-openbio.readthedocs.io/projects/seqmule/en/latest/" rel="nofollow">https://doc-openbio.readthedocs.io/projects/seqmule/en/latest/</a></p>]]></description>
	<dc:creator>BioStar</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/41231/phd-student-bio-informatician-in-computational-protein-modeling</guid>
  <pubDate>Sun, 23 Feb 2020 03:46:46 -0600</pubDate>
  <link></link>
  <title><![CDATA[PhD student / Bio-informatician in computational protein modeling]]></title>
  <description><![CDATA[
<p>PhD student / Bio-informatician in computational protein modeling<br />Job Profile<br />You will perform research on drug/protein interaction analysis in the context of lung cancer, using computational protein modeling. You will implement existing models predicting drug efficacy, related to EGFR-driven cancer. You will translate these models to novel oncogenes, including ROS1. You will validate these models against experimental data from a parallel project, with the final goal of deployment of your methods into clinical decision making. Your work will be embedded in an international network consisting of both academic partners and ROS1-NSCLC patient organizations.</p>

<p>Requirements</p>

<p>You are (or soon will be) a master in bio-informatics. You have strong ICT skills and you are eager to fully submerge into the world of protein modeling. You have good experience with Linux and one or more programming languages as well as knowledge of tertiary structure analysis. Candidates with a Master degree in one of the life sciences (Biomedical sciences, Biochemistry, Bio-engineering, Biostatistics, …), with relevant interest and extended experience in this field are also welcome. A general background cancer biology and genetics is needed. You are willing and eligible to apply for a personal PhD fellowship with the Flemish FWO (FWO.be). Therefore, it is required that you hold a master degree from a European university, and have not obtained your master diploma more than three years ago (see FWO website for detailed conditions). Proficiency in English, and good communication skills, both oral and written, are required. You are highly motivated, and you like to work in an interactive research team. You are willing to work on a 4-year PhD project starting beginning of 2020.</p>

<p>What we offer</p>

<p>We offer a one year position, as a PhD student, which can be extended up to 4 year upon positive evaluation, even if a personal fellowship application is not successful. Wages are according to the standard Flemish bursary levels for PhD students.</p>

<p>Interested?<br />For additional information please contact dr. Geert Vandeweyer. To apply, send a copy of your CV including details of your relevant skills and a motivation letter by e-mail to dr. Geert Vandeweyer (geert.vandeweyer@uantwerpen.be) before March 15, 2020.</p>

<p>Source:https://academicpositions.be/ad/university-of-antwerp/2020/phd-student-bio-informatician-in-computational-protein-modeling/141252?utm_source=jooble&amp;utm_medium=cpc&amp;utm_campaign=jooble</p>
]]></description>
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