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	<title><![CDATA[BOL: Related items]]></title>
	<link>https://bioinformaticsonline.com/related/9695?</link>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/4943/molecular-genetics-lecture</guid>
	<pubDate>Fri, 27 Sep 2013 04:24:45 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/4943/molecular-genetics-lecture</link>
	<title><![CDATA[Molecular Genetics Lecture]]></title>
	<description><![CDATA[<p><span>"Robert Sapolsky makes interdisciplinary connections between behavioral biology and molecular genetic influences. He relates protein synthesis and point mutations to microevolutionary change, and discusses conflicting theories of gradualism and punctuated equilibrium and the influence of epigenetics on development theories."&nbsp;</span></p>
<p><span>"<span><strong>Robert Sapolsky</strong> is an American neuroendocrinologist, professor of biology, neuroscience, and neurosurgery at Stanford University, researcher and author" ----Wikipedia</span></span></p><p>Address of the bookmark: <a href="http://www.youtube.com/watch?v=_dRXA1_e30o" rel="nofollow">http://www.youtube.com/watch?v=_dRXA1_e30o</a></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4961/genetics-epigenetics-and-disease</guid>
	<pubDate>Fri, 27 Sep 2013 11:32:55 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4961/genetics-epigenetics-and-disease</link>
	<title><![CDATA[Genetics, epigenetics and disease]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/SHpfkNRscOc" frameborder="0" allowfullscreen></iframe>Royal Society GlaxoSmithKline Prize Lecture given by Professor Adrian Bird CBE FMedSci FRS on Tuesday 22 January 2013.

Adrian Bird CBE FMedSci FRS is the Buchanan Chair of Genetics at the University of Edinburgh.

The human genome sequence has been available for more than a decade, but its significance is still not fully understood. While most human genes have been identified, there is much to learn about the DNA signals that control them. This lecture described an unusually short DNA sequence, just two base pairs long, CG, which occurs in several chemically different forms. Defects in signalling by CG are implicated in disease. For example, the autism spectrum disorder Rett syndrome is caused by loss of a protein that reads methylated CG and affects the activity of genes.

The Royal Society GlaxoSmithKline Prize Lecture is awarded for original contributions to medical and veterinary sciences published within ten years from the date of the award.]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/news/view/10966/genxpro-gmbh</guid>
	<pubDate>Thu, 22 May 2014 07:18:35 -0500</pubDate>
	<link>https://bioinformaticsonline.com/news/view/10966/genxpro-gmbh</link>
	<title><![CDATA[GenXPro GmbH]]></title>
	<description><![CDATA[<p><strong>GenXPro</strong>&nbsp;GMbH is service provider for entire spectrum of nucleotide-based information&nbsp;of any biological sample. By combining intelligent data reduction techniques and&nbsp;latest next generation sequencing technologies, our service portfolio provides most accurate and cost efficient solutions for&nbsp;transcriptomic-, genomic- or epigenomic research.</p><p><span><span><strong><span>GENXPRO GMBH</span>,&nbsp;</strong></span></span><span>ALTENH&Ouml;FERALLEE 3,&nbsp;</span><span>60438 FRANKFURT MAIN,&nbsp;</span><span>GERMANY</span></p><p><span><span><strong>Website</strong></span>:&nbsp;<a href="http://www.genxpro.info/products_and_services/"></a><a href="http://www.genxpro.info/products_and_services/">http://www.genxpro.info/products_and_services/</a></span></p><p><span><strong>PHONE</strong>: +49 (0)69- 95 73 97 10,&nbsp;FAX: +49 (0)69- 95 73 97 06</span></p><p><span>EMAIL: info@genxpro.de</span></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/researchlabs/view/28036/prof-chandrasekhar-kanduri-laboratory</guid>
  <pubDate>Fri, 24 Jun 2016 16:59:43 -0500</pubDate>
  <link></link>
  <title><![CDATA[Prof. Chandrasekhar Kanduri Laboratory]]></title>
  <description><![CDATA[
<p>Our lab has been interested in understanding how long noncoding RNAs control tumor initiation and progression, in addition to use them as potential biomarkers in diagnosis and therapy. We have been using neuroblastoma, a childhood cancer, as a model system to understand the functional role of long noncoding RNAs in cancer development and progression. By using new RNA sequencing technology on neuroblastoma tumors from a large group of Swedish children including both high-risk and low-risk neuroblastomas (108), we have identified several long noncoding RNAs that could have potential role in diagnosis and therapy. We are currently exploring the functional role of these differentially expressed long noncoding RNA in nuroblastoma progression and development.</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/4042/a-brief-introduction-to-genetics</guid>
	<pubDate>Wed, 28 Aug 2013 06:49:38 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/4042/a-brief-introduction-to-genetics</link>
	<title><![CDATA[A Brief Introduction to Genetics]]></title>
	<description><![CDATA[<iframe src="http://player.vimeo.com/video/20898800?byline=0" width="" height="" frameborder="0" webkitAllowFullScreen allowFullScreen></iframe>A Brief Introduction to Genetics is a short documentary film that explores the history of genetics & genomics and the underlying concepts that provide the foundational knowledge that today's research is built upon. The film describes the history of genetics, from Gregor Mendel, to concepts such as DNA and the genetic code. Having introduced the fundamental ideas of genetics, the film moves on to describe the current techniques used to study genetics. Finally, the film explores the connection of these core concepts to genomics and bioinformatics.]]></description>
	
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	<guid isPermaLink="true">https://bioinformaticsonline.com/videolist/watch/13267/the-genome-10k-project</guid>
	<pubDate>Tue, 29 Jul 2014 09:11:04 -0500</pubDate>
	<link>https://bioinformaticsonline.com/videolist/watch/13267/the-genome-10k-project</link>
	<title><![CDATA[The Genome 10K Project]]></title>
	<description><![CDATA[<iframe width="" height="" src="https://www.youtube-nocookie.com/embed/B57xDIGtCT0" frameborder="0" allowfullscreen></iframe>https://genome10k.soe.ucsc.edu

The Genome 10K project aims to assemble a genomic zoo—a collection of DNA sequences representing the genomes of 10,000 vertebrate species, approximately one for every vertebrate genus. The trajectory of cost reduction in DNA sequencing suggests that this project will be feasible within a few years. Capturing the genetic diversity of vertebrate species would create an unprecedented resource for the life sciences and for worldwide conservation efforts.

The growing Genome 10K Community of Scientists (G10KCOS), made up of leading scientists representing major zoos, museums, research centers, and universities around the world, is dedicated to coordinating efforts in tissue specimen collection that will lay the groundwork for a large-scale sequencing and analysis project.]]></description>
	
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  <guid isPermaLink='true'>https://bioinformaticsonline.com/opportunity/view/18580/faculty-positions-at-central-university-of-punjab-bathinda</guid>
  <pubDate>Wed, 22 Oct 2014 10:45:37 -0500</pubDate>
  <link></link>
  <title><![CDATA[Faculty Positions at CENTRAL UNIVERSITY OF PUNJAB, BATHINDA]]></title>
  <description><![CDATA[
<p>Advertisement No. T/NT-01 (2014)</p>

<p>Faculty Positions<br />The Central University of Punjab (CUP), Bathinda will be having the Schools and Departments as given in Table-I. The University invites applications from eligible candidates for the posts of Professors (Pay Band Rs. 37400-67000 with AGP of Rs. 10, 000/-), Associate Professors (Pay Band Rs.37400-67000 with AGP of Rs. 9,000/-) and Assistant Professors (Pay Band Rs.15600-39100 with AGP of Rs. 6,000/-)</p>

<p>POSITION AVAILABLE IN THE AREA OF SPECIALIZTION</p>

<p>3. Bioinformatics,</p>

<p>Procedure to apply: Application forms along with API form complete in all respect along with necessary documents and application fee of Rs. 750/-. (Rs. 250/- for Scheduled Caste/Scheduled Tribe/Person with disabilities) should be sent to:</p>

<p>Registrar (Officiating)<br />Central University of Punjab<br />City Campus, Mansa Road<br />Bathinda-151 001</p>

<p>Application forms from the prospective candidates are accepted upto November 10, 2014.</p>

<p>Based on the qualification of the candidates and the need of the university, the applications received will be processed through appropriately constituted selection committees shortly. Minimum qualification can be relaxed in case of exceptionally outstanding candidate. For further details visit www.cup.ac.in; www.centralunipunjab.com; www.cup.edu.in</p>

<p>The candidate should download the application form available at website www.cup.ac.in;<br />www.centralunipunjab.com; and submit it complete in all respects on or before 10th November 2014.</p>

<p>Those who have applied earlier need to submit Academic Performance Index (API) form, 5 copies of Summary of the Application Form (available at: www.cup.ac.in; www.centralunipunjab.com and Updated CV if not updated recently (without application fee).</p>

<p>http://cup.edu.in/Faculty_details_and_general_instructions.pdf</p>

<p>http://cup.edu.in/Final%20Application%20and%20summary%20Sheet%20and%20Api%20form.pdf</p>
]]></description>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/pages/view/34146/phylogenetic-molecular-genetics-terms-and-definitions</guid>
	<pubDate>Tue, 08 Aug 2017 08:20:31 -0500</pubDate>
	<link>https://bioinformaticsonline.com/pages/view/34146/phylogenetic-molecular-genetics-terms-and-definitions</link>
	<title><![CDATA[Phylogenetic &amp; Molecular Genetics Terms and Definitions]]></title>
	<description><![CDATA[<p><strong>analog </strong>-- A feature that appears similar in two taxa which have originated from two different ancestors.</p><p><strong>ancestor</strong> -- Any organism, population, or species from which some other organism, population, or species is descended by reproduction.</p><p><strong>apomorphy </strong>-- specialized (=derived) characters of an organism.</p><p><strong>basal group</strong> -- The earliest diverging group within a clade; for instance, to hypothesize that sponges are basal animals is to suggest that the lineage(s) leading to sponges diverged from the lineage that gave rise to all other animals.</p><p><strong>biological classification </strong>-- The orderly arrangement of organisms in hierarchical system that ideally reflects evolutionary history.</p><p><strong>cDNA</strong> -- Complementary DNA; DNA that is synthesized, by reverse transcriptase, from a Messenger RNA template ( Messenger RNA contains the coded information for protein synthesis).</p><p><strong>character</strong> -- Heritable trait possessed by an organism.</p><p><strong>character state</strong> -- characters are usually described in terms of their states, for example: "hair present" vs. "hair absent," where "hair" is the character, and "present" and "absent" are its states.</p><p><strong>clade</strong> -- A monophyletic taxon; a group of organisms which includes the most recent common ancestor of all of its members and all of the descendants of that most recent common ancestor. From the Greek word "klados", meaning branch or twig.</p><p><strong>cladogenesis</strong> -- The development of a new clade; the splitting of a single lineage into two distinct lineages; speciation.</p><p><strong>cladogram</strong> -- A diagram, resulting from a cladistic analysis, which depicts a hypothetical branching sequence of lineages leading to the taxa under consideration. The points of branching within a cladogram are called nodes. All taxa occur at the endpoints of the cladogram.</p><p><strong>convergence</strong> -- Similarities which have arisen independently in two or more organisms that are not closely related. Contrast with homology.&nbsp;</p><p><strong>crown group</strong> -- All the taxa descended from a major cladogenesis event, recognized by possessing the clade's synapomorphy. See: stem group.</p><p><strong>derived</strong> -- Describes a character state that is present in one or more subclades, but not all, of a clade under consideration. A derived character state is inferred to be a modified version of the primitive condition of that character, and to have arisen later in the evolution of the clade. For example, "presence of hair" is a primitive character state for all mammals, whereas the "hairlessness" of whales is a derived state for one subclade within the Mammalia.</p><p><strong>diversity</strong> -- Term used to describe numbers of taxa, or variation in morphology.&nbsp;</p><p><strong>evolution</strong> -- Darwin's definition: descent with modification. The term has been variously used and abused since Darwin to include everything from the origin of man to the origin of life.</p><p><strong>evolutionary tree</strong> -- A diagram which depicts the hypothetical phylogeny of the taxa under consideration. The points at which lineages split represent ancestor taxa to the descendant taxa appearing at the terminal points of the cladogram.</p><p><strong>expressed sequence tag (EST)</strong> -- A partial coding sequence isolated at random from a cDNA library, used for identification and mapping of coding sequences, for discovery of new genes and (by reference to sequence data banks) for discovery of identities with other genes.</p><p><strong>extinction</strong> -- When all the members of a clade or taxon die, the group is said to be extinct.</p><p><strong>genetic marker -- </strong>A DNA sequence that can be recognized and thus used to characterize the larger DNA sequence and the chromosome in which it occurs.&nbsp;</p><p><strong>homolog </strong>-- A feature that appears similar in two or more taxa with a common ancestor that also possessed that feature.</p><p><strong>homology</strong> -- Two structures are considered homologous when they are inherited from a common ancestor which possessed the structure. This may be difficult to determine when the structure has been modified through descent.</p><p><strong>hypothesis</strong> -- A concept or idea that can be falsified by various scientific methods.</p><p><strong>ingroup</strong> -- In a cladistic analysis, the set of taxa which are hypothesized to be more closely related to each other than any are to the outgroup.</p><p><strong>lineage</strong> -- Any continuous line of descent; any series of organisms connected by reproduction by parent of offspring.</p><p><strong>monophyletic</strong> -- Term applied to a group of organisms which includes the most recent common ancestor of all of its members and all of the descendants of that most recent common ancestor. A monophyletic group is called a clade.</p><p><strong>outgroup</strong> -- In a cladistic analysis, any taxon used to help resolve the polarity of characters, and which is hypothesized to be less closely related to each of the taxa under consideration than any are to each other.</p><p><strong>paraphyletic</strong> -- Term applied to a group of organisms which includes the most recent common ancestor of all of its members, but not all of the descendants of that most recent common ancestor.</p><p><strong>parsimony</strong> -- Refers to a rule used to choose among possible cladograms, which states that the cladogram implying the least number of changes in character states is the best.</p><p><strong>phylogenetics</strong> -- Field of biology that deals with the relationships between organisms. It includes the discovery of these relationships, and the study of the causes behind this pattern.</p><p><strong>phylogeny</strong> -- The evolutionary relationships among organisms; the patterns of lineage branching produced by the true evolutionary history of the organisms being considered.</p><p><strong>plesiomorphy</strong> -- A primitive character state for the taxa under consideration.</p><p><strong>polarity of characters</strong> -- The states of characters used in a cladistic analysis, either original or derived. Original characters are those acquired by an ancestor deeper in the phylogeny than the most recent common ancestor of the taxa under consideration. Derived characters are those acquired by the most recent common ancestor of the taxa under consideration.</p><p><strong>polyphyletic</strong> -- Term applied to a group of organisms which does not include the most recent common ancestor of those organisms; the ancestor does not possess the character shared by members of the group.</p><p><strong>primitive</strong> -- Describes a character state that is present in the common ancestor of a clade. A primitive character state is inferred to be the original condition of that character within the clade under consideration. For example, "presence of hair" is a primitive character state for all mammals, whereas the "hairlessness" of whales is a derived state for one subclade within the Mammalia.</p><p><strong>radiation</strong> -- Event of rapid cladogenesis, believed to occur under conditions where a new feature permits a lineage to move into a new niche or new habitat, and is then called an adaptive radiation.</p><p><strong>rank</strong> -- In traditional taxonomy, taxa are ranked according to their level of inclusiveness. Thus a genus contains one or more species, a family includes one or more genera, and so on.</p><p><strong>relatedness</strong> -- Two clades are more closely related when they share a more recent common ancestor between them than they do with any other clade.</p><p><strong>repetitive DNA</strong> -- Sequences of DNA that are found to be repeated, sometimes thousands of times over.&nbsp;&nbsp;</p><p><strong>reticulation</strong> -- Joining of separate lineages on a phylogenetic tree, generally through hybridization or through lateral gene transfer. Fairly common in certain land plant clades; reticulation is thought to be rare among metazoans.</p><p><strong>selection</strong> -- Process which favors one feature of organisms in a population over another feature found in the population. This occurs through differential reproduction -- those with the favored feature produce more offspring than those with the other feature, such that they become a greater percentage of the population in the next generation.</p><p><strong>sister group</strong> -- The two clades resulting from the splitting of a single lineage.</p><p><strong>stem group</strong> -- All the taxa in a clade preceding a major cladogenesis event. They are often difficult to recognize because they may not possess synapomorpies found in the crown group.</p><p><strong>sympleisiomorphy</strong> &ndash; A ancestral character shared by the taxa under consideration</p><p><strong>synapomorphy</strong> -- A character which is derived, and because it is shared by the taxa under consideration, is used to infer common ancestry (shared derived state).</p><p><strong>synteny</strong> -- Portions of chromosomes in which gene order is conserved.&nbsp;</p><p><strong>systematics</strong> -- Field of biology that deals with the diversity of life. Systematics is usually divided into the two areas of phylogenetics and taxonomy.</p><p><strong>taxon</strong> -- Any named group of organisms, not necessarily a clade</p><p><strong>taxonomy</strong> -- The science of naming and classifying organisms.&nbsp;</p>]]></description>
	<dc:creator>Poonam Mahapatra</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/5402/key-bioinformatics-scientists</guid>
	<pubDate>Wed, 09 Oct 2013 13:37:07 -0500</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/5402/key-bioinformatics-scientists</link>
	<title><![CDATA[Key Bioinformatics Scientists]]></title>
	<description><![CDATA[<p>Address of the bookmark: <a href="http://www.iscb.org/iscb-leadership-a-staff-/officers-and-board-directors" rel="nofollow">http://www.iscb.org/iscb-leadership-a-staff-/officers-and-board-directors</a></p>]]></description>
	<dc:creator>Rahul Agarwal</dc:creator>
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	<guid isPermaLink="true">https://bioinformaticsonline.com/bookmarks/view/40711/vg-variation-graph-data-structures-interchange-formats-alignment-genotyping-and-variant-calling-methods</guid>
	<pubDate>Tue, 28 Jan 2020 03:53:24 -0600</pubDate>
	<link>https://bioinformaticsonline.com/bookmarks/view/40711/vg-variation-graph-data-structures-interchange-formats-alignment-genotyping-and-variant-calling-methods</link>
	<title><![CDATA[VG: variation graph data structures, interchange formats, alignment, genotyping, and variant calling methods]]></title>
	<description><![CDATA[<p><em>Variation graphs</em>&nbsp;provide a succinct encoding of the sequences of many genomes. A variation graph (in particular as implemented in vg) is composed of:</p>
<ul>
<li><em>nodes</em>, which are labeled by sequences and ids</li>
<li><em>edges</em>, which connect two nodes via either of their respective ends</li>
<li><em>paths</em>, describe genomes, sequence alignments, and annotations (such as gene models and transcripts) as walks through nodes connected by edges</li>
</ul><p>Address of the bookmark: <a href="https://github.com/vgteam/vg" rel="nofollow">https://github.com/vgteam/vg</a></p>]]></description>
	<dc:creator>Jit</dc:creator>
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