BOL: My posts on The ResearchLabs

Prof. Dr. med. Andreas Ramming

Wed, 07 Aug 2019 03:25:48 -0500

In many autoimmune diseases, a misdirected immune response leads to chronic inflammation and subsequently to fibrotic and degenerative tissue remodeling. Therapeutic options are available for inflammatory joint diseases, but only about 40% of patients respond to these existing therapies on a permanent basis. In the remaining cases, these therapies miss their target from the beginning or later during the course of treatment failure. There are currently no causal therapies available for the treatment of fibrotic autoimmune diseases such as systemic sclerosis. Therefore, there is an urgent need to develop new therapeutic options for the treatment of fibrotic and synovitic autoimmune diseases. His group is therefore deal with the molecular mechanisms of these misdirected signaling pathways for the development of novel, targeted therapies

http://www.medizin3.uk-erlangen.de/forschung/arbeitsgruppen/matrixbiologie-entzuendliche-signalwege-in-arthritis-und-fibrose/

Prof. Dr. rer. nat. Jeanette Erdmann's Lab

Sun, 17 Dec 2017 10:29:18 -0600

Her prestigious lab working on Integrative and Experimental genomics to understand the underlying mechanism thats able to define an inherited predisposition of coronary artery disease (CAD) and myocardial infarction (MI) via GWAS, different Sequencing technologies and Functional genomics. Her lab is located at Institute for Cardio-genetics Universität zu Lübeck, Maria-Goeppert-Str. 1, 23562 Lübeck.

Tel +49 451 3101 8301
cardiogenetics(at)uni-luebeck.de

http://cardiogenetics-luebeck.de/

Genomic approaches to study global regulation of gene expression in the mouse immune system

Fri, 15 Dec 2017 22:10:12 -0600

This group seeks to elucidate the principles of protein structure evolution, higher order protein structure and protein folding, and the principles underlying protein complex formation and organization. We have a longstanding interest in understanding gene expression regulation, and in our wetlab at the Sanger Institute use mouse T helper cells as a model of cell differentiation.

This lab focuses on two main areas: (1) transcription factors and the regulation of gene expression, and (2) physical protein-protein interactions and protein complexes

This group also aim to elucidate transcriptional regulatory networks orchestrating T helper cell differentiation and plasticity. Using the T helper cell system, we want to answer questions such as: What is the hierarchy and kinetics of molecular events that contribute to changes in gene expression? Are the kinetics of these interactions graded or switch-like?

http://www.sanger.ac.uk/science/groups/teichmann-group

The Minerva Research Group for Bioinformatics

Tue, 27 May 2014 15:48:14 -0500

The focus of the bioinformatics group is to use computational approaches to gain an insight into genome evolution in primates.

http://www.eva.mpg.de/genetics/bioinformatics/overview.html?Fsize=0%2C%20%40%2F%27

Kelso Group
Department of Evolutionary Genetics
Max Planck Institute for Evolutionary Anthropology
Deutscher Platz 6
04103 Leipzig
Germany
Phone: +49 341 3550 500

Job:
http://www.eva.mpg.de/genetics/bioinformatics/jobs.html?Fsize=0%2C%2B%40

Science for Life Laboratory (SciLifeLab)-Sweden

Sat, 10 May 2014 06:22:30 -0500

Science for Life Laboratory (SciLifeLab) is a national center for molecular biosciences with focus on health and environmental research. The center combines frontline technical expertise with advanced knowledge of translational medicine and molecular bioscience. SciLifeLab is a national resource and a collaboration between four universities: Karolinska Institutet, KTH Royal Institute of Technology, Stockholm University and Uppsala University.

Webpage : https://www.scilifelab.se/about-us/
Opportunity: https://www.scilifelab.se/about-us/career/