BOL: Category: All

MAB Lab

Sun, 15 Sep 2013 09:28:09 -0500

Seamless integration of a series of biological processes finally manifests as what we perceive as "Life". In order to gain insights about life and its manifestations in different forms (from single cell to multicellular forms), we seek to understand the underlying mechanistic basis of biological processes at the molecular level and integrate them at the systems level. Towards this, we employ a combination of approaches encompassing Bioinformatics & Computational Biology, Biochemical and Biophysical approaches and X-ray crystallography. Our current research interests pertains to RNA Biology and Molecular Evolution.

More @ http://www.iitg.ernet.in/banand/index.html

Bioinformatics Infrastructure Facility

Sun, 15 Sep 2013 09:22:25 -0500

The Bioinformatics Infrastructure Facility has started working in the year 2007 at Presidency College, Kolkata. It is one of the premier institutes of India and boasts of a rich heritage and great alumni. The Infrastructure Facility has a dedicated team headed by Sayak Ganguli and ably supported by Priayanka Dhar. The coordinator of the facility is Abhijit Datta of the Post Graduate Department of Botany. The lab mainly focusses on the analysis of the RNA Induced Silencing Complex. Recent highlights include the presentation of a paper at the RNAi World Congress.

More @ http://bioinfo-presiuniv.edu.in/index.php

SOWDHAMINI Lab

Sun, 15 Sep 2013 09:19:12 -0500

Genome sequencing projects have enormous potential for benefiting human endeavors. However, just as acquiring a language's vocabulary does not enable one to speak it, databases that list the amino acid composition of proteins do not directly tell us much about these proteins' higher-level structure and function. The most productive way to indirectly exploit these databases has been to start with the small number of proteins that are fully-characterised and to assume that other "similar" proteins will have a related structure and function. Proteins with very similar amino acid sequence are "no-brainers", but the real test, which our group largely focuses on, is to detect the "essential" similarity in proteins whose non-critical sections have experienced random rearrangements during evolution. In such cases functionally similar proteins may have less than 25% sequence overlap.

More @ http://www.ncbs.res.in/sowdhamini/groups_sowdhamini.htm

Huber Lab

Mon, 09 Sep 2013 21:57:03 -0500

The Huber group develops computational and statistical methods to design and analyse novel experimental approaches in genetics and cell biology.

Future projects and goals

Large-scale systematic maps of gene-gene and gene-environment interactions by automated phenotyping, using image analysis, machine learning, sparse model building and causal inference.
DNA-, RNA- and ChIP-Seq and their applications to gene expression regulation: statistical and computational foundations.
Cancer genomics, genomes as biomarkers, cancer phylogeny.
Image analysis for systems biology: measuring the dynamics of cell cycle and of cell migration of individual cells under normal conditions and many different perturbations (RNAi, drugs).

More @ http://www.embl.de/research/units/genome_biology/huber/index.html

Medical Epigenomics Lab

Fri, 06 Sep 2013 10:05:31 -0500

The Medical Epigenomics Lab is part of the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences. The lab is directed by Christoph Bock, who is a Principal Investigator at CeMM and a Guest Professor in Medical University of Vienna's Department of Laboratory Diagnostics.

More at http://www.medical-epigenomics.org/