BOL: Category: All

ShendureLab

Thu, 28 Dec 2017 09:57:50 -0600

The mission of our lab is to develop and apply new technologies and methods for genetics, genomics and molecular biology. Most of our work exploits next-generation DNA sequencing which is effectively emerging as a broadly enabling microscope for the measurement of biological phenomena. Our ongoing work generally falls into six areas. These are listed below as links to representative publications in each area.

Developing New Molecular Methods

Genomic Approaches to Developmental Biology

Massively Parallel Functional Genomics

Translating Genomics to the Clinic

Genetic Basis of Human Disease

Genome Sequencing Technologies

http://krishna.gs.washington.edu/index.html
http://www.gs.washington.edu/faculty/shendure.htm

Prof. Dr. rer. nat. Jeanette Erdmann's Lab

Sun, 17 Dec 2017 10:29:18 -0600

Her prestigious lab working on Integrative and Experimental genomics to understand the underlying mechanism thats able to define an inherited predisposition of coronary artery disease (CAD) and myocardial infarction (MI) via GWAS, different Sequencing technologies and Functional genomics. Her lab is located at Institute for Cardio-genetics Universität zu Lübeck, Maria-Goeppert-Str. 1, 23562 Lübeck.

Tel +49 451 3101 8301
cardiogenetics(at)uni-luebeck.de

http://cardiogenetics-luebeck.de/

Genomic approaches to study global regulation of gene expression in the mouse immune system

Fri, 15 Dec 2017 22:10:12 -0600

This group seeks to elucidate the principles of protein structure evolution, higher order protein structure and protein folding, and the principles underlying protein complex formation and organization. We have a longstanding interest in understanding gene expression regulation, and in our wetlab at the Sanger Institute use mouse T helper cells as a model of cell differentiation.

This lab focuses on two main areas: (1) transcription factors and the regulation of gene expression, and (2) physical protein-protein interactions and protein complexes

This group also aim to elucidate transcriptional regulatory networks orchestrating T helper cell differentiation and plasticity. Using the T helper cell system, we want to answer questions such as: What is the hierarchy and kinetics of molecular events that contribute to changes in gene expression? Are the kinetics of these interactions graded or switch-like?

http://www.sanger.ac.uk/science/groups/teichmann-group

Talkowski Laboratory

Mon, 11 Dec 2017 12:17:42 -0600

The Talkowski laboratory explores the impact of genomic alterations on human neurodevelopment and neuropsychiatric disorders, and the application of innovations in sequencing technology to genetic diagnostics. Mike received undergraduate degrees in Biology and Psychology and a Ph.D. in Human Genetics with a focus in genetic epidemiology and psychiatric genetics. He joined the Center for Human Genetic Research (CHGR) of Massachusetts General Hospital, the Department of Neurology in Harvard Medical School, and the Program in Medical and Population Genetics at the Broad Institute as a Postdoctoral Fellow with Dr. James Gusella, Director of the CHGR, in 2008 to study the genetic etiology of neurodevelopmental disorders, particularly autism spectrum disorders. He was appointed to the faculty of the CHGR and Harvard Medical School in 2011.

http://talkowski.mgh.harvard.edu

Salzberg lab

Mon, 15 May 2017 05:14:01 -0500

We are a computational biology lab that develops novel methods for analysis of DNA and RNA sequences. Our research includes software for aligning and assembling RNA-seq data, whole-genome assembly, and microbiome analysis. We work closely with biomedical scientists to apply these methods to current problems arising in a broad spectrum of biological and medical research areas. We’re also part of the Center for Computational Biology, a group of 20+ faculty members and their labs at Johns Hopkins working on computational, statistical, and mathematical methods that can turn massive genomic data sets into biologically and clinically useful information.

https://salzberg-lab.org/