https://bioinformaticsonline.com/snippets/view/43403/oneliner-to-convert-lower-case-to-sequence-masked-with-ns? https://bioinformaticsonline.com/snippets/view/43403/oneliner-to-convert-lower-case-to-sequence-masked-with-ns Tue, 28 Sep 2021 04:47:05 -0500 https://bioinformaticsonline.com/snippets/view/43403/oneliner-to-convert-lower-case-to-sequence-masked-with-ns perl -pe '/^[^>]/ and $_=~ s/[a-z]/N/g' genomic.fna > genomic.N-masked.fna awk '{if(/^[^>]/)gsub(/[a-z]/,"N");print $0}' genomic.fna > genomic.N-masked.fna]]> Surabhi Chaudhary