LAST can:
Handle big sequence data, e.g:
Compare two vertebrate genomes
Align billions of DNA reads to a genome
Indicate the reliability of each aligned column.
Use sequence quality data properly.
Compare DNA to proteins, with frameshifts.
Compare PSSMs to sequences
Calculate th...
Tags: LAST, Bioinformatics, Mapping, Match, Align, Sequences, Compare
Quickly #Finding #Orthologs as Reciprocal Best #Hits with #BLAT, #LAST, and #UBLAST: How Much Do We Miss? http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0101850
Tags: Finding, Orthologs, Hits, BLAT, LAST, UBLAST